Paul D Brown

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi request reprint Prospective study of quality of life in adults with newly diagnosed high-grade gliomas
    Paul D Brown
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    J Neurooncol 76:283-91. 2006
  2. pmc The neurocognitive effects of radiation in adult low-grade glioma patients
    Paul D Brown
    Division of Radiation Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Neuro Oncol 5:161-7. 2003
  3. ncbi request reprint Irradiation of the inguinal lymph nodes in patients of differing body habitus: a comparison of techniques and resulting normal tissue complication probabilities
    Paul D Brown
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN, USA
    Med Dosim 29:217-22. 2004
  4. ncbi request reprint Adult patients with supratentorial pilocytic astrocytomas: a prospective multicenter clinical trial
    Paul D Brown
    Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 58:1153-60. 2004
  5. doi request reprint Adjuvant whole brain radiotherapy: strong emotions decide but rational studies are needed
    Paul D Brown
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 70:1305-9. 2008
  6. pmc Phase I/II trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North Central Cancer Treatment Group Study N0177
    Paul D Brown
    Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Clin Oncol 26:5603-9. 2008
  7. ncbi request reprint Detrimental effects of tumor progression on cognitive function of patients with high-grade glioma
    Paul D Brown
    Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 24:5427-33. 2006
  8. ncbi request reprint Importance of baseline mini-mental state examination as a prognostic factor for patients with low-grade glioma
    Paul D Brown
    Division of Radiation Ocology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 59:117-25. 2004
  9. ncbi request reprint Will improvement in quality of life (QOL) impact fatigue in patients receiving radiation therapy for advanced cancer?
    Paul Brown
    Department of Oncology, Mayo Clinic Rochester, Rochester, MN 55905, USA
    Am J Clin Oncol 29:52-8. 2006
  10. doi request reprint A prospective study of quality of life in adults with newly diagnosed high-grade gliomas: comparison of patient and caregiver ratings of quality of life
    Paul D Brown
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Oncol 31:163-8. 2008

Detail Information

Publications92

  1. ncbi request reprint Prospective study of quality of life in adults with newly diagnosed high-grade gliomas
    Paul D Brown
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    J Neurooncol 76:283-91. 2006
    ..To assess baseline quality of life (QOL) and its prognostic importance for adults with newly diagnosed high-grade gliomas, we analyzed QOL and outcome data prospectively collected in three phase II high-grade glioma protocols...
  2. pmc The neurocognitive effects of radiation in adult low-grade glioma patients
    Paul D Brown
    Division of Radiation Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Neuro Oncol 5:161-7. 2003
    ..The weight of evidence suggests only sporadic, limited neurocognitive damage from focal radiotherapy at the doses usually prescribed for low-grade gliomas...
  3. ncbi request reprint Irradiation of the inguinal lymph nodes in patients of differing body habitus: a comparison of techniques and resulting normal tissue complication probabilities
    Paul D Brown
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN, USA
    Med Dosim 29:217-22. 2004
    ..Technique 1 for ectomorphs and mesomorphs and techniques 2 and 6 for endomorphs were optimal techniques for providing relatively homogeneous dose distributions within the target area while minimizing the dose to the femoral heads...
  4. ncbi request reprint Adult patients with supratentorial pilocytic astrocytomas: a prospective multicenter clinical trial
    Paul D Brown
    Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 58:1153-60. 2004
    ..Supratentorial pilocytic astrocytomas in adults are uncommon. A prospective clinical trial was conducted to obtain clinical and outcome data in these patients...
  5. doi request reprint Adjuvant whole brain radiotherapy: strong emotions decide but rational studies are needed
    Paul D Brown
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 70:1305-9. 2008
    ..Currently, two Phase III trials are underway, one in Europe and one in North America, that will determine the effect of adjuvant WBRT on patients' quality of life, neurocognitive function, and survival...
  6. pmc Phase I/II trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North Central Cancer Treatment Group Study N0177
    Paul D Brown
    Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Clin Oncol 26:5603-9. 2008
    ..Erlotinib, a selective EGFR inhibitor, was combined with temozolomide (TMZ) and radiotherapy (RT) in a phase I/II trial...
  7. ncbi request reprint Detrimental effects of tumor progression on cognitive function of patients with high-grade glioma
    Paul D Brown
    Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 24:5427-33. 2006
    ..To assess the cognitive performance of high-grade glioma patients, prospectively collected cognitive performance data were analyzed...
  8. ncbi request reprint Importance of baseline mini-mental state examination as a prognostic factor for patients with low-grade glioma
    Paul D Brown
    Division of Radiation Ocology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 59:117-25. 2004
    ....
  9. ncbi request reprint Will improvement in quality of life (QOL) impact fatigue in patients receiving radiation therapy for advanced cancer?
    Paul Brown
    Department of Oncology, Mayo Clinic Rochester, Rochester, MN 55905, USA
    Am J Clin Oncol 29:52-8. 2006
    ..In this project, we examined the impact that participation in a randomized controlled trial of a multidisciplinary intervention designed to impact overall QOL had on fatigue for advanced cancer patients actively receiving treatment...
  10. doi request reprint A prospective study of quality of life in adults with newly diagnosed high-grade gliomas: comparison of patient and caregiver ratings of quality of life
    Paul D Brown
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Oncol 31:163-8. 2008
    ..To examine whether a caregiver can provide reliable proxy quality of life (QOL) ratings of their adult significant other with a newly diagnosed high-grade glioma...
  11. doi request reprint Predictors of survival in contemporary practice after initial radiosurgery for brain metastases
    Anna Likhacheva
    Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Int J Radiat Oncol Biol Phys 85:656-61. 2013
    ..The purpose of this study was to determine whether, following multivariate adjustment, the number and volume of BM held prognostic significance in a cohort of patients initially treated with SRS alone...
  12. pmc Effect of tumor subtype on survival and the graded prognostic assessment for patients with breast cancer and brain metastases
    Paul W Sperduto
    University of Minnesota Gamma Knife, Minneapolis Radiation Oncology, Minneapolis, MN, USA
    Int J Radiat Oncol Biol Phys 82:2111-7. 2012
    ..The diagnosis-specific Graded Prognostic Assessment (GPA) was published to clarify prognosis for patients with brain metastases. This study refines the existing Breast-GPA by analyzing a larger cohort and tumor subtype...
  13. pmc Randomized trial of radiation therapy plus procarbazine, lomustine, and vincristine chemotherapy for supratentorial adult low-grade glioma: initial results of RTOG 9802
    Edward G Shaw
    Department of Radiation Oncology, Wake Forest University School of Medicine, 2000 W First St, Winston Salem, NC 27104, USA
    J Clin Oncol 30:3065-70. 2012
    ....
  14. pmc Validation of EORTC prognostic factors for adults with low-grade glioma: a report using intergroup 86-72-51
    Thomas B Daniels
    Department of Radiation Oncology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 81:218-24. 2011
    ..We sought to independently validate this prognostic index with a separate prospectively collected data set (Intergroup 86-72-51)...
  15. ncbi request reprint Oncodiagnosis panel: 2002. Primary glial neoplasm or less likely an intracranial abscess
    Paul D Brown
    Department of Oncology, Mayo Clinic, 200 SW 1st St, Rochester, MN 55905, USA
    Radiographics 23:1591-611. 2003
  16. ncbi request reprint Effects of radiotherapy on cognitive function in patients with low-grade glioma measured by the folstein mini-mental state examination
    Paul D Brown
    Mayo Clinic, Division of Radiation Oncology, Rochester, MN 55905, USA
    J Clin Oncol 21:2519-24. 2003
    ..To assess the neurocognitive effects of cranial radiotherapy on patients with low-grade gliomas, we analyzed cognitive performance data collected in a prospective, intergroup clinical trial...
  17. doi request reprint Long-term follow-up of dose-adapted and reduced-field radiotherapy with or without chemotherapy for central nervous system germinoma
    Ashley W Jensen
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 77:1449-56. 2010
    ..To update our institutional experience with neoadjuvant chemotherapy and minimized radiotherapy vs. radiation monotherapy for intracranial germinoma...
  18. doi request reprint Brain metastases from melanoma: is there a role for concurrent temozolomide in addition to whole brain radiation therapy?
    Steven E Schild
    Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ 85259, USA
    Am J Clin Oncol 33:633-6. 2010
    ..This study was performed to evaluate the addition of temozolomide (TMZ) to whole brain radiotherapy (WBRT) for brain metastases from melanoma...
  19. ncbi request reprint A prospective study of quality of life in adults with newly diagnosed high-grade gliomas: the impact of the extent of resection on quality of life and survival
    Paul D Brown
    Division of Radiation Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Neurosurgery 57:495-504; discussion 495-504. 2005
    ..To describe the quality of life (QOL) over time for adults with newly diagnosed high-grade gliomas and to examine the relationship between QOL and outcome data collected in three prospective cooperative group clinical trials...
  20. doi request reprint Adult low-grade glioma: 19-year experience at a single institution
    Ryan S Youland
    College of Medicine Departments of Pathology Neurosurgery Neurology Radiation Oncology, Mayo Clinic, Rochester, MN Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
    Am J Clin Oncol 36:612-9. 2013
    ..To determine prognostic factors and optimal timing of postoperative radiation therapy (RT) in adult low-grade gliomas...
  21. ncbi request reprint Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: results of North Central Cancer Treatment Group protocol N0177
    Sunil Krishnan
    Department of Radiation Oncology, Mayo Clinic College of Medicine, Rochester, MN, USA
    Int J Radiat Oncol Biol Phys 65:1192-9. 2006
    ..To evaluate the toxicity and maximum tolerated dose (MTD) of erlotinib plus radiation therapy (RT) in patients with glioblastoma multiforme (GBM) in a multicenter phase I trial...
  22. ncbi request reprint Improving the quality of life of geriatric cancer patients with a structured multidisciplinary intervention: a randomized controlled trial
    Maria I Lapid
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN 55905, USA
    Palliat Support Care 5:107-14. 2007
    ..To examine the potential impact of elderly age on response to participation in a structured, multidisciplinary quality-of-life (QOL) intervention for patients with advanced cancer undergoing radiation therapy...
  23. doi request reprint The effect of tumor subtype on the time from primary diagnosis to development of brain metastases and survival in patients with breast cancer
    Paul W Sperduto
    Minneapolis Radiation Oncology, University of Minnesota Gamma Knife, Minneapolis, MN, USA
    J Neurooncol 112:467-72. 2013
    ..Patients with Basal and HER2 tumor subtypes have short TPDBM. Prospective studies are needed to determine if screening brain MRIs are indicated in patients with Basal or HER2 subtypes...
  24. doi request reprint Factors associated with endocrine deficits after stereotactic radiosurgery of pituitary adenomas
    James L Leenstra
    Department of Radiation Oncology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Neurosurgery 67:27-32; discussion 32-3. 2010
    ..To analyze the factors associated with anterior pituitary deficits after pituitary adenoma stereotactic radiosurgery (SRS)...
  25. pmc Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic
    David A Schomas
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Neuro Oncol 11:437-45. 2009
    ..Postoperative RT was associated with improved OS and PFS and is recommended for patients after subtotal resection or biopsy...
  26. ncbi request reprint Treatment options for brain metastases from melanoma
    Robert R McWilliams
    Division of Medical Oncology, Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Expert Rev Anticancer Ther 5:809-20. 2005
    ..Future directions include combined modality therapy, the incorporation of novel agents and careful consideration of the structure of clinical trials for this disease...
  27. ncbi request reprint Central neurocytoma: management recommendations based on a 35-year experience
    James L Leenstra
    Department of Radiation Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 67:1145-54. 2007
    ..METHODS AND MATErials: The data from 45 patients with central neurocytomas diagnosed between 1971 and 2003 were retrospectively evaluated. Various combinations of surgery, radiotherapy (RT), and chemotherapy had been used for treatment...
  28. ncbi request reprint Gamma knife radiosurgery of radiation-induced intracranial tumors: local control, outcomes, and complications
    Ashley W Jensen
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 62:32-7. 2005
    ..To determine local control (LC) and complication rates for patients who underwent radiosurgery for radiation-induced intracranial tumors...
  29. doi request reprint CHOD/BVAM chemotherapy and whole-brain radiotherapy for newly diagnosed primary central nervous system lymphoma
    Nadia N Laack
    Department of Radiation Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Int J Radiat Oncol Biol Phys 81:476-82. 2011
    ....
  30. pmc North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme
    Jann N Sarkaria
    Mayo Clinic Rochester, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 81:468-75. 2011
    ..On the basis of promising preclinical data, the safety and tolerability of therapy with the mTOR inhibitor RAD001 in combination with radiation (RT) and temozolomide (TMZ) was evaluated in this Phase I study...
  31. ncbi request reprint Cognitive function after radiotherapy for supratentorial low-grade glioma: a North Central Cancer Treatment Group prospective study
    Nadia N Laack
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 63:1175-83. 2005
    ..To evaluate the effects of cranial radiotherapy (RT) on cognitive function in patients with supratentorial low-grade glioma...
  32. ncbi request reprint Measuring spiritual quality of life in patients with cancer
    Mary E Johnson
    Department of Chaplain Services, Mayo Clinic, Rochester, MN 55905, USA
    J Support Oncol 5:437-42. 2007
    ....
  33. ncbi request reprint A higher radiotherapy dose is associated with more durable palliation and longer survival in patients with metastatic melanoma
    Kenneth R Olivier
    Department of Radiation Oncology, University of Florida Health Science Center, Gainesville, Florida 32610 0385, USA
    Cancer 110:1791-5. 2007
    ..Oncologists are often reluctant to recommend radiotherapy (RT) to palliate metastatic melanoma due to a perception that this tumor is "radioresistant." The Mayo Clinic experience was analyzed to determine the efficacy of palliative RT...
  34. ncbi request reprint Cognitive rehabilitation and problem-solving to improve quality of life of patients with primary brain tumors: a pilot study
    Dona E C Locke
    Division of Psychology, Mayo Clinic, Scottsdale, AZ 85259, USA
    J Support Oncol 6:383-91. 2008
    ....
  35. doi request reprint Randomized controlled trial of maintaining quality of life during radiotherapy for advanced cancer
    Matthew M Clark
    Department of Psychiatry and Psychology, Mayo Clinic Rochester, Rochester, Minnesota 55905, USA
    Cancer 119:880-7. 2013
    ..Psychosocial interventions often address only 1 domain of quality of life (QOL), are offered to patients with early-stage cancer, do not include the caregiver, and are delivered after cancer treatment has been completed...
  36. doi request reprint Single-fraction radiosurgery of benign intracranial meningiomas
    Bruce E Pollock
    Department of Neurological Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Neurosurgery 71:604-12; discussion 613. 2012
    ..Stereotactic radiosurgery (SRS) of benign intracranial meningiomas is an accepted management option for well-selected patients...
  37. doi request reprint Proton beam radiotherapy versus three-dimensional conformal stereotactic body radiotherapy in primary peripheral, early-stage non-small-cell lung carcinoma: a comparative dosimetric analysis
    O Kenneth Macdonald
    Department of Radiation Oncology, Mayo Clinic, 200 1st Street S W, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 75:950-8. 2009
    ..We analyzed the dosimetric differences between PT and SBRT in treating primary peripheral early-stage non-small-cell lung cancer...
  38. ncbi request reprint Gamma knife radiosurgery for patients with nonfunctioning pituitary adenomas: results from a 15-year experience
    Bruce E Pollock
    Department of Neurological Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 70:1325-9. 2008
    ..To evaluate the efficacy and complications of stereotactic radiosurgery for patients with nonfunctioning pituitary adenomas (NFA)...
  39. doi request reprint Systemic lupus erythematosus, radiotherapy, and the risk of acute and chronic toxicity: the Mayo Clinic Experience
    Melva E Pinn
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 71:498-506. 2008
    ..To determine the acute and chronic toxic effects of radiotherapy in patients with systemic lupus erythematosus (SLE)...
  40. pmc The relationship between six-month progression-free survival and 12-month overall survival end points for phase II trials in patients with glioblastoma multiforme
    Karla V Ballman
    Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Neuro Oncol 9:29-38. 2007
    ..Finally, there was a strong association between progression-free survival status and overall survival. PFS6 seems to be a reasonable end point for phase II trials in patients with recurrent glioblastoma...
  41. doi request reprint Early pulmonary toxicity following lung stereotactic body radiation therapy delivered in consecutive daily fractions
    Michael C Stauder
    Department of Radiation Oncology, Mayo Clinic, Rochester, USA
    Radiother Oncol 99:166-71. 2011
    ..Identify the incidence of early pulmonary toxicity in a cohort of patients treated with lung stereotactic body radiation therapy (SBRT) on consecutive treatment days...
  42. pmc Validation of single-item linear analog scale assessment of quality of life in neuro-oncology patients
    Dona E C Locke
    Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, Arizona 85259, USA
    J Pain Symptom Manage 34:628-38. 2007
    ..The data suggest that the single-item LASA scales are valid for assessing QOL of cancer patients and are an appropriate alternative when a shorter instrument is warranted...
  43. doi request reprint Gamma knife radiosurgery for patients with prolactin-secreting pituitary adenomas
    Shota Tanaka
    Department of Neurological Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    World Neurosurg 74:147-52. 2010
    ..To evaluate the efficacy of stereotactic radiosurgery (SRS) for patients with prolactin (PRL)-secreting pituitary adenomas that were refractory to medical management...
  44. doi request reprint Stereotactic radiosurgery for recurrent or unresectable pilocytic astrocytoma
    Christopher L Hallemeier
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA
    Int J Radiat Oncol Biol Phys 83:107-12. 2012
    ..To report the outcomes in patients with recurrent or unresectable pilocytic astrocytoma (PA) treated with Gamma Knife stereotactic radiosurgery (SRS)...
  45. doi request reprint Stereotactic body radiation therapy in spinal metastases
    Kamran A Ahmed
    Mayo Medical School, College of Medicine, Mayo Clinic, Rochester, MN, USA
    Int J Radiat Oncol Biol Phys 82:e803-9. 2012
    ..Based on reports of safety and efficacy, stereotactic body radiotherapy (SBRT) for treatment of malignant spinal tumors was initiated at our institution. We report prospective results of this population at Mayo Clinic...
  46. pmc Combination of temsirolimus (CCI-779) with chemoradiation in newly diagnosed glioblastoma multiforme (GBM) (NCCTG trial N027D) is associated with increased infectious risks
    Jann N Sarkaria
    Mayo Clinic Rochester, 200 First Street SW, Rochester, MN 55905, USA
    Clin Cancer Res 16:5573-80. 2010
    ..The mammalian target of rapamycin (mTOR) functions within the phosphoinositide 3-kinase/Akt signaling pathway as a critical modulator of cell survival...
  47. pmc Radiation-induced optic neuritis after pituitary adenoma radiosurgery in a patient with multiple sclerosis: case report
    Thomas B Daniels
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    J Neurooncol 93:263-7. 2009
    ..To describe a rare case of optic neuritis onset after Gamma Knife stereotactic radiosurgery...
  48. doi request reprint Melanoma-induced brain metastases
    Robert R McWilliams
    Division of Medical Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Expert Rev Anticancer Ther 8:743-55. 2008
    ..Future directions include combined-modality therapy, the incorporation of novel agents, and careful consideration of the structure of clinical trials for this disease...
  49. ncbi request reprint Organ preservation for advanced laryngeal carcinoma
    Robert L Foote
    Department of Radiation Oncology, Mayo Clinic College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Head Neck 28:689-96. 2006
    ..Inclusion of patients with mobile vocal cords on larynx preservation trials may lead to overstatement of larynx preservation (LPR) and survival (OS) rates...
  50. ncbi request reprint Oncodiagnosis panel: 2002. Patient's symptoms not related to the lesion seen in the MR images
    Paul D Brown
    Department of Oncology, Mayo Clinic, 200 SW 1st St, Rochester, MN 55905, USA
    Radiographics 23:1591-611. 2003
  51. ncbi request reprint Properly selected patients with multiple brain metastases may benefit from aggressive treatment of their intracranial disease
    Bruce E Pollock
    Department of Neurological Surgery, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    J Neurooncol 61:73-80. 2003
    ....
  52. ncbi request reprint A pilot study of high-dose intraarterial cisplatin chemotherapy with concomitant accelerated radiotherapy for patients with previously untreated T4 and selected patients with T3N0-N3M0 squamous cell carcinoma of the upper aerodigestive tract
    Robert L Foote
    Division of Radiation Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA
    Cancer 103:559-68. 2005
    ....
  53. ncbi request reprint Innovation in the management of brain metastases
    Ravi D Rao
    Department of Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Oncology (Williston Park) 21:473-81; discussion 482, 484, 489. 2007
    ..Novel therapies to enhance radiation responsiveness are also under investigation. In the current review, we discuss recent developments in the management of patients with brain metastases...
  54. doi request reprint Temozolomide use in adult patients with gliosarcoma: an evolving clinical practice
    Gary V Walker
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 97, Houston, TX 77030, USA
    J Neurooncol 112:83-9. 2013
    ..Patients diagnosed in the TMZ era in the SEER database display an improved OS, although the explanation for this finding requires further elucidation...
  55. ncbi request reprint Treatment of brain metastases from melanoma
    Robert R McWilliams
    Division of Medical Oncology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 78:1529-36. 2003
    ..Chemotherapy may be gaining a role with newer agents that penetrate the blood-brain barrier. Combined modality therapy appears to be the future direction of treatment of multiple metastases...
  56. doi request reprint Willingness of cancer patients to help family members to quit smoking
    Yolanda I Garces
    Department of Radiation Oncology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Psychooncology 20:724-9. 2011
    ..As a first step in this line of research, we sought to explore interest in playing a supportive role for smoking cessation as well as correlates of such interest among cancer survivors...
  57. ncbi request reprint Choroid plexus papillomas: a single institutional experience
    Sunil Krishnan
    Division of Radiation Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Neurooncol 68:49-55. 2004
    ..To determine the long-term outcome of resected choroid plexus papillomas (CPPs)...
  58. ncbi request reprint Radiosurgery as primary management for meningiomas extending into the internal auditory canal
    Bruce E Pollock
    Department of Neurological Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Stereotact Funct Neurosurg 82:98-103. 2004
    ..Radiosurgery is an excellent alternative to surgical excision for meningiomas in this location, especially if a subtotal resection is likely or a hearing-sacrificing operation such as a translabyrinthine approach is contemplated...
  59. ncbi request reprint Cognitive sequelae of brain radiation in adults
    Nadia N Laack
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Semin Oncol 31:702-13. 2004
    ..Further studies need to be undertaken to elucidate the degree and cause of cognitive decline in adult patients undergoing multimodality therapy for cranial tumors...
  60. ncbi request reprint Radiosurgery for cranial base chordomas and chondrosarcomas
    Sunil Krishnan
    Division of Radiation Oncology, Department of Oncology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Neurosurgery 56:777-84; discussion 777-84. 2005
    ..To evaluate the efficacy and toxicity of radiosurgery in the treatment of cranial base chordoma and chondrosarcoma...
  61. pmc Low-grade gliomas in older patients: long-term follow-up from Mayo Clinic
    David A Schomas
    Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA
    Cancer 115:3969-78. 2009
    ..Low-grade gliomas (LGGs) are uncommon in older patients, and long-term clinical behavior and prognostic factors are not well defined in this group...
  62. ncbi request reprint Informed consent in advanced laryngeal cancer
    Robert L Foote
    Department of Radiation Oncology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Head Neck 29:230-5. 2007
    ..This study was designed to evaluate the relationship between the informed consent process and the treatment received by patients with advanced laryngeal cancer...
  63. ncbi request reprint Repeat radiosurgery for idiopathic trigeminal neuralgia
    Bruce E Pollock
    Department of Neurological Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 61:192-5. 2005
    ..Although frequently performed, the efficacy and safety of repeat trigeminal neuralgia radiosurgery is not well described...
  64. ncbi request reprint Oncodiagnosis panel: 2002. Optic nerve glioma or optic nerve meningioma
    Paul D Brown
    Department of Oncology, Mayo Clinic, 200 SW 1st St, Rochester, MN 55905, USA
    Radiographics 23:1591-611. 2003
  65. ncbi request reprint A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma
    Robert B Jenkins
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer Res 66:9852-61. 2006
    ..Like combined 1p/19q deletion, the 1;19 translocation is associated with superior OS and progression-free survival in low-grade glioma patients...
  66. ncbi request reprint A study on the radiation tolerance of the optic nerves and chiasm after stereotactic radiosurgery
    Scott L Stafford
    Division of Radiation Oncology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 55:1177-81. 2003
    ..To evaluate the risk of clinically significant radiation optic neuropathy (RON) for patients having stereotactic radiosurgery of benign tumors adjacent to the optic apparatus...
  67. ncbi request reprint Phase II trial of procarbazine, lomustine, and vincristine as initial therapy for patients with low-grade oligodendroglioma or oligoastrocytoma: efficacy and associations with chromosomal abnormalities
    Jan C Buckner
    Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Clin Oncol 21:251-5. 2003
    ....
  68. ncbi request reprint Oncodiagnosis panel: 2002. Metastatic NSCLC
    Paul D Brown
    Department of Oncology, Mayo Clinic, 200 SW 1st St, Rochester, MN 55905, USA
    Radiographics 23:1591-611. 2003
  69. pmc Recurrence following neurosurgeon-determined gross-total resection of adult supratentorial low-grade glioma: results of a prospective clinical trial
    Edward G Shaw
    Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Neurosurg 109:835-41. 2008
    ..In 1998, the Radiation Therapy Oncology Group initiated a Phase II study of observation for adults < 40 years old with cerebral low-grade glioma who underwent a neurosurgeon-determined gross-total resection (GTR)...
  70. ncbi request reprint Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response
    Jann N Sarkaria
    Department of Radiation Oncology, Laboratory Medicine and Pathology, and Biostatistics, Mayo Clinic, Rochester, Minnesota, USA
    Clin Cancer Res 12:2264-71. 2006
    ..The intent of the current study was to address this relationship using several EGFR-amplified glioblastoma xenografts in an orthotopic athymic mouse model...
  71. ncbi request reprint Quality of life of caregivers of patients with advanced-stage cancer
    Matthew M Clark
    Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA
    Am J Hosp Palliat Care 23:185-91. 2006
    ..Further investigation is warranted in this area, including interventions specifically designed and targeted to both reduce caregiver burden and to improve caregiver QOL...
  72. ncbi request reprint Long-term results of irradiation for paraganglioma
    Aaron J Krych
    Mayo Clinic College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 65:1063-6. 2006
    ..Few data exist regarding long-term tumor control and late effects after EBRT or SRS...
  73. ncbi request reprint Stereotactic radiosurgery for brainstem metastases: Survival, tumor control, and patient outcomes
    Aamir Hussain
    Department of Radiation Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 67:521-4. 2007
    ..Patients with brainstem metastases have limited treatment options. In this study, we reviewed outcomes after stereotactic radiosurgery (SRS) in the management of patients with brainstem metastases...
  74. ncbi request reprint A historical prospective cohort study of carotid artery stenosis after radiotherapy for head and neck malignancies
    Paul D Brown
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 63:1361-7. 2005
    ..To determine carotid artery stenosis incidence after radiotherapy for head-and-neck neoplasms...
  75. ncbi request reprint Multiple sclerosis, brain radiotherapy, and risk of neurotoxicity: the Mayo Clinic experience
    Robert C Miller
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN55905, USA
    Int J Radiat Oncol Biol Phys 66:1178-86. 2006
    ..The aim of this study was a retrospective assessment of neurotoxicity in patients with multiple sclerosis (MS) receiving external beam radiotherapy (EBRT) to the brain...
  76. doi request reprint Pituitary tumor type affects the chance of biochemical remission after radiosurgery of hormone-secreting pituitary adenomas
    Bruce E Pollock
    Departments of Neurological Surgery and Radiation Oncology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Neurosurgery 62:1271-6; discussion 1276-8. 2008
    ..Confounding variables include histology, radiation dose, use of pituitary-suppressive medications, and length of follow-up...
  77. ncbi request reprint Stereotactic radiosurgery for patients with "radioresistant" brain metastases
    Paul D Brown
    Division of Radiation Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Neurosurgery 51:656-65; discussion 665-7. 2002
    ..Our aim was to evaluate the efficacy of stereotactic radiosurgery (SRS) for the treatment of patients with brain metastases that have been determined to be "radioresistant" on the basis of histological examination...
  78. doi request reprint Prognosis and treatment of spinal cord astrocytoma
    Kiernan J Minehan
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 73:727-33. 2009
    ..To identify the prognostic factors for spinal cord astrocytoma and determine the effects of surgery and radiotherapy on outcome...
  79. ncbi request reprint Radiosurgery for arteriovenous malformations of the basal ganglia, thalamus, and brainstem
    Bruce E Pollock
    Department of Neurologic Surgery, Division of Radiation Oncology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    J Neurosurg 100:210-4. 2004
    ..The goal of this paper was to study these outcomes...
  80. ncbi request reprint Radiosurgery of growth hormone-producing pituitary adenomas: factors associated with biochemical remission
    Bruce E Pollock
    Department of Neurological Surgery, Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Neurosurg 106:833-8. 2007
    ..The authors reviewed outcomes after stereotactic radiosurgery for patients with acromegaly and analyzed factors associated with biochemical remission...
  81. pmc Phase II NCCTG trial of RT + irinotecan and adjuvant BCNU plus irinotecan for newly diagnosed GBM
    Kurt A Jaeckle
    Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, FL 32224, USA
    J Neurooncol 99:73-80. 2010
    ..This regimen was not significantly active and radiosensitization was not observed. Non-EIAC patients with UGT1A1*28 variant alleles appear particularly sensitive to toxicity from irinotecan...
  82. pmc Reversible, strokelike migraine attacks in patients with previous radiation therapy
    J D Bartleson
    Departments of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Neuro Oncol 5:121-7. 2003
    ..Radiation-induced vascular changes could provoke the episodes, with or without an underlying migraine diathesis. Recognition of this syndrome can help avoid invasive testing...
  83. ncbi request reprint Evaluation of gamma knife radiosurgery in the treatment of oligodendrogliomas and mixed oligodendroastrocytomas
    Atom Sarkar
    Department of Neurologic Surgery and the Division of Radiation Oncology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    J Neurosurg 97:653-6. 2002
    ..The goal of this study was to evaluate the safety and efficacy of radiosurgery in the management of patients with oligodendrogliomas (ODGs) or mixed oligoastrocytomas (OGAs)...
  84. ncbi request reprint Outcome in adult low-grade glioma: the impact of prognostic factors and treatment
    David Schiff
    Neuro Oncology Center, University of Virginia Health Sciences Center, Box 800432, Charlottesville, VA 22908 0432, USA
    Neurology 69:1366-73. 2007
    ..We review contemporary knowledge regarding prognostic factors, our current evidence-based understanding of the roles and timing of radiation and chemotherapy, and ongoing clinical trials that will further elucidate management of LGGs...
  85. ncbi request reprint A methodology to determine margins by EPID measurements of patient setup variation and motion as applied to immobilization devices
    Joann I Prisciandaro
    Division of Radiation Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Med Phys 31:2978-88. 2004
    ..Finally, this methodology provides direct evidence of treatment variation and thus can demonstrate with confidence, the superiority of one technique over another...
  86. ncbi request reprint Chronic toxicity risk after radiotherapy for patients with systemic sclerosis (systemic scleroderma) or systemic lupus erythematosus: association with connective tissue disorder severity
    Douglas G Gold
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Radiother Oncol 87:127-31. 2008
    ..Building on our prior experience, we postulated that disease severity, as measured by the number of organ systems involved, may predict chronic radiation toxicity risk...
  87. ncbi request reprint Role and relevance of neurocognitive assessment in clinical trials of patients with CNS tumors
    Christina A Meyers
    Department of Neuro Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 24:1305-9. 2006
    ..Including this aspect of patient evaluation in addition to survival and time to tumor progression will yield better risk-versus-benefit assessments as well as provide a basis for improving interventions...
  88. ncbi request reprint Utility of PET/CT imaging performed early after surgical resection in the adjuvant treatment planning for head and neck cancer
    Stephanie A Shintani
    Department of Otolaryngology Head and Neck Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
    Int J Radiat Oncol Biol Phys 70:322-9. 2008
    ..To evaluate the utility of positron emission tomography (PET)/computed tomography (CT) early after surgical resection and before postoperative adjuvant radiation therapy...
  89. ncbi request reprint Central nervous system tumors
    Jan C Buckner
    Division of Medical Oncology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 82:1271-86. 2007
    ..This article provides an overview of current diagnostic and treatment approaches for patients with primary and metastatic brain tumors...
  90. ncbi request reprint Is there a role for radiation therapy in the management of Hürthle cell carcinoma?
    Robert L Foote
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 56:1067-72. 2003
    ..To determine the role that radiation therapy may have in the management of resected, unresectable, and metastatic Hürthle cell carcinoma...
  91. ncbi request reprint Resolution of diabetes insipidus following gamma knife surgery for a solitary metastasis to the pituitary stalk. Case report
    Mark P Piedra
    Mayo Medical School, Division of Radiation Oncology and Endocrinology, Rochester, Minnesota 55905, USA
    J Neurosurg 101:1053-6. 2004
    ..Three months after GKS the patient was able to reduce the medication she required for the DI. There was no evidence of pituitary failure and no negative effect on her vision...
  92. ncbi request reprint Low-grade gliomas: the debate continues
    Paul D Brown
    Department of Oncology, Mayo Clinic Rochester, MN 55905, USA
    Curr Oncol Rep 8:71-7. 2006
    ..In this article we review the pertinent LGG literature published over the past few years and its impact on the management of LGGs...