J E Blair

..Although the majority of patients in our study with isolated IgM reactivity by EIA had probable or confirmed coccidioidomycosis, this result must be interpreted with caution for asymptomatic patients...

..We describe a facilitated peer mentoring program in our institution's department of medicine...

..Treatment may alleviate some of the symptoms of coccidioidomycosis originally attributed to the concomitant liver disease...

..The prevalence of coccidioidal antibodies was low among potential organ donor candidates, but the risk of donor-derived coccidioidomycosis remains unknown and further study is warranted...

..Immunosuppressed persons who contract coccidioidomycosis, however, are at increased risk for disseminated infection...

..This review summarizes recent findings of studies and case reports about coccidioidomycosis in transplant recipients...

..Transplant recipients may have quiescent disseminated coccidioidomycosis that is reactivated by immunosuppression after withdrawal of suppressive antifungal therapy...

..Malaria is the most common cause of febrile illness in travelers returning from endemic areas, and prompt evaluation is essential to initiating timely treatment. Various resources are available to assist in this evaluation...

..This article summarizes the pathogenesis, epidemiology, clinical manifestations, diagnostic studies, and treatment of coccidioidal meningitis, and highlights new information regarding this devastating infection...

..In recent years, the incidence of coccidioidomycosis has increased in areas of endemicity, and previous studies have found the highest incidence of coccidioidal infection in Arizona among persons in older age groups...

..4%). Close surveillance and targeted prophylaxis are safe and effective alternatives to universal prophylaxis for CM in patients undergoing liver transplantation in an endemic area...

..The infection was limited to skin and soft tissue, and treatment consisted of local debridement and liposomal amphotericin B. Outcome was successful...

..Treatment options include amphotericin B or azoles. Secondary prophylaxis is recommended because relapse is frequent...

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..We present the first successful case of a kidney transplant in a patient after treatment for coccidioidal meningitis without post-transplant reactivation of the coccidioidal infection...

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..Symptoms and signs mistakenly attributed to terminal liver disease may actually be caused by coccidioidomycosis...

..Up-to-date travel health resources, including sites on the World Wide Web, can assist physicians in advising patients about immunizations and other preventive measures recommended for travel to endemic areas...

..We discuss the most common clinical manifestations, the best way to make the diagnosis, and the treatment of common infections...

..This patient survived with oral antifungal therapy. Coccidioidomycosis was not a frequent event in liver transplant recipients from areas of low endemicity who relocated to our highly endemic area...

..Lack of mentoring has been suggested as a possible contributor to this difference...

..This approach has many similarities to the construction of a quilt during a "quilting bee."..

..This review describes the presentation, evaluation, and basic treatment of infectious syndromes caused by these bacterial, viral, protozoal, fungal, and parasitic zoonoses...

..We provide clinical, diagnostic, and management approaches for clinicians in nonendemic areas who might encounter coccidioidomycosis in transplant recipients...

..There are limited reports of 2009 H1N1 influenza in transplant recipients. We report on our experience with hospitalized transplant recipients with 2009 H1N1 influenza virus...

..The clinical features and treatment recommendations are summarized. Medical practitioners need to be alert to the possibility of coccidioidomycosis in persons with recent travel to or residence in an area where the disease is endemic...

..This article reviews the types and locations of disseminated infections, as well as diagnostic studies and treatment of this difficult-to-treat manifestation of coccidioidomycosis...

..bantiana fungal infections have become more common in recent years. Aggressive and continuous treatment with voriconazole may offer an improved chance of survival in these patients...

..The fungal infection can result in pulmonary sequelae, including nodules, cavities, and complications requiring treatment by the thoracic surgeon...

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..Future patient outcomes may improve with early identification of patients who have risk factors for invasive fungal infections and with the development of new molecular diagnostic techniques for early detection...

..A multitude of new contraceptive agents are now available. We review new hormonal contraceptive options and discuss newer oral agents, extended-cycle contraception, and innovative delivery methods...

..Although there are no established approaches to preventing coccidioidomycosis among these patients, studies are underway examining the use of prophylactic azole antifungals with documented prior coccidioidal infection...

..Treatment for acute rejection and induction with antithymocyte globulin did not appear to increase the risk of subsequent coccidioidomycosis...

..Coccidioidomycosis is a common cause of CAP in our patient population. In the absence of distinguishing clinical features, coccidioidal pneumonia can be identified only with appropriate laboratory studies...

..CONCLUSIONS: Male genitourinary coccidioidomycosis is rare but it should be considered in the differential diagnosis of patients with exposure to the endemic area who present with prostatitis or epididymitis...

..The risk of coccidioidal infection among transplant recipients visiting in or relocating to an endemic area is low, and routine prophylaxis for this group is not recommended...

..In the elderly, pericardiectomy may be complicated by coagulopathy and septic shock. Despite potential toxicity, use of antifungal therapy early postoperatively offers the best chance for survival...

..Coccidioidomycosis is an endemic fungal infection of the southwestern United States that causes considerable morbidity and mortality in transplant recipients, often as the result of reactivated infection...

..Anatomical issues, diagnostic studies, and data related to treatment of this form of extrapulmonary coccidioidomycosis are reviewed in this article...

..Immunosuppressed persons have the ability to mount a serologic response to coccidioidomycosis, but in some circumstances, multiple methods may be required to improve detection...

..Corticosteroids, immunosuppressive medications, and tumor necrosis factor inhibitors (TNFIs) appeared to be risk factors for symptomatic, but not disseminated coccidioidomycosis...

..32/65 [49%], respectively; P = .004). Coccidioides fungemia is an uncommon manifestation of fulminant, disseminated coccidioidomycosis. Survival is poorest in immunocompromised patients or those not receiving antifungal therapy...

..No false-positive IgM assays were observed. We conclude that the false-positive rate of the EIA IgM is low, and that an isolated positive EIA IgM should prompt further follow-up and diagnostic testing...

..The association of brachial plexopathy with Q fever infection, described in other rare instances, may merit consideration in individual cases, depending on clinical context...

..Future studies should evaluate the efficacy of tight glycemic control on the outcome of coccidioidal infection...

..A prospective evaluation is required to address the optimal use of coccidioidal serologic tests, antifungal protocols, and secondary prophylaxis in these patients...

..The infection was fatal in 4 of the 6 patients whose cases we reviewed. We conclude that coccidioidal endocarditis is an uncommon manifestation of Coccidioides infection that connotes a poor prognosis...

..Presentation can mimic bacterial infection or malignant neoplasm, leading to delayed or inappropriate treatment. We describe an unusual ulcerative lesion of the eyelid that led to a diagnosis of disseminated coccidioidomycosis...

..CONCLUSION: Routine use of SBD in patients undergoing liver transplantation is not associated with significant benefit...

..Our hope is that the practical suggestions offered here will prove useful to the next generation of women physicians and that each subsequent generation will become ever more successful in filling these roles...

..This article reviews migraine prevention strategies with an emphasis on specific therapies for each stage of a woman's life...