Joanna M Biernacka

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc Replication of genome wide association studies of alcohol dependence: support for association with variation in ADH1C
    Joanna M Biernacka
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, United States of America
    PLoS ONE 8:e58798. 2013
  2. pmc Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence
    Joanna M Biernacka
    Divisions of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
    Int J Neuropsychopharmacol 16:271-8. 2013
  3. doi request reprint Pharmacogenomics of antidepressant induced mania: a review and meta-analysis of the serotonin transporter gene (5HTTLPR) association
    Joanna M Biernacka
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
    J Affect Disord 136:e21-9. 2012
  4. pmc Assessment of genotype imputation methods
    Joanna M Biernacka
    Department of Health Sciences Research, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905 USA
    BMC Proc 3:S5. 2009
  5. pmc Exploring causality via identification of SNPs or haplotypes responsible for a linkage signal
    Joanna M Biernacka
    Department of Medical Genetics, University of Cambridge, UK
    Genet Epidemiol 31:727-40. 2007
  6. pmc A composite-likelihood approach for identifying polymorphisms that are potentially directly associated with disease
    Joanna M Biernacka
    Department of Health Sciences Research, Division of Biostatistics, Mayo Clinic, Rochester, MN 55905, USA
    Eur J Hum Genet 17:644-50. 2009
  7. doi request reprint Alcohol craving as a predictor of relapse
    Terry D Schneekloth
    Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Addict 21:S20-6. 2012
  8. doi request reprint Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states
    Victor M Karpyak
    Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Neuropsychopharmacol 16:975-85. 2013
  9. doi request reprint Trazodone and alcohol relapse: a retrospective study following residential treatment
    Bhanu Prakash Kolla
    Department of Psychiatry, Mayo Clinic, Rochester, Minnesota, USA
    Am J Addict 20:525-9. 2011
  10. doi request reprint Association of GATA4 sequence variation with alcohol dependence
    Victor M Karpyak
    Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
    Addict Biol 19:312-5. 2014

Collaborators

Detail Information

Publications39

  1. pmc Replication of genome wide association studies of alcohol dependence: support for association with variation in ADH1C
    Joanna M Biernacka
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, United States of America
    PLoS ONE 8:e58798. 2013
    ..Further studies should investigate the association of other polymorphisms in this gene with alcohol dependence and related alcohol-use phenotypes...
  2. pmc Genome-wide gene-set analysis for identification of pathways associated with alcohol dependence
    Joanna M Biernacka
    Divisions of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
    Int J Neuropsychopharmacol 16:271-8. 2013
    ..These findings demonstrate the utility of GSA in the study of complex disease, and suggest specific directions for further research into the genetic architecture of alcohol dependence...
  3. doi request reprint Pharmacogenomics of antidepressant induced mania: a review and meta-analysis of the serotonin transporter gene (5HTTLPR) association
    Joanna M Biernacka
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
    J Affect Disord 136:e21-9. 2012
    ..This review and meta-analysis evaluates the evidence for association between the serotonin transporter gene promoter polymorphism (5HTTLPR) and AIM...
  4. pmc Assessment of genotype imputation methods
    Joanna M Biernacka
    Department of Health Sciences Research, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905 USA
    BMC Proc 3:S5. 2009
    ..However, in both situations, none of the imputation-based tests provide the same level of evidence of association as the complete data at SNPs strongly associated with disease...
  5. pmc Exploring causality via identification of SNPs or haplotypes responsible for a linkage signal
    Joanna M Biernacka
    Department of Medical Genetics, University of Cambridge, UK
    Genet Epidemiol 31:727-40. 2007
    ..We study properties of the proposed methods by simulation and apply them to type 1 diabetes data for ASPs and their parents at candidate SNP and microsatellite marker loci in the Insulin (INS) gene region...
  6. pmc A composite-likelihood approach for identifying polymorphisms that are potentially directly associated with disease
    Joanna M Biernacka
    Department of Health Sciences Research, Division of Biostatistics, Mayo Clinic, Rochester, MN 55905, USA
    Eur J Hum Genet 17:644-50. 2009
    ..We use simulations to demonstrate that the proposed method can lead to substantial power increases over the earlier single SNP analyses...
  7. doi request reprint Alcohol craving as a predictor of relapse
    Terry D Schneekloth
    Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Am J Addict 21:S20-6. 2012
    ..This study evaluated craving intensity measured with the Penn Alcohol Craving Scale (PACS) at admission and discharge from residential treatment as a predictive factor of relapse after treatment...
  8. doi request reprint Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states
    Victor M Karpyak
    Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Neuropsychopharmacol 16:975-85. 2013
    ..These findings support the hypothesis that sequence variation in the PDYN gene contributes to both alcohol dependence and the induction of negative craving in alcohol-dependent subjects...
  9. doi request reprint Trazodone and alcohol relapse: a retrospective study following residential treatment
    Bhanu Prakash Kolla
    Department of Psychiatry, Mayo Clinic, Rochester, Minnesota, USA
    Am J Addict 20:525-9. 2011
    ..Our retrospective study of a complex patient population discharged from a residential treatment setting did not find an association between trazodone use at discharge and relapse rates at 6 months...
  10. doi request reprint Association of GATA4 sequence variation with alcohol dependence
    Victor M Karpyak
    Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
    Addict Biol 19:312-5. 2014
    ..009) but no association with rs13273672. Further studies are needed to identify potential causal GATA4 variation(s) and the functional mechanism(s) contributing to this association. ..
  11. doi request reprint Genetic susceptibility loci, environmental exposures, and Parkinson's disease: a case-control study of gene-environment interactions
    Sun Ju Chung
    Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
    Parkinsonism Relat Disord 19:595-9. 2013
    ..Here we investigated the interactions between SNPs in those three susceptibility genes and environmental exposures (pesticides application, tobacco smoking, coffee drinking, and alcohol drinking) also associated with PD susceptibility...
  12. doi request reprint Do interactions between SNCA, MAPT, and LRRK2 genes contribute to Parkinson's disease susceptibility?
    Joanna M Biernacka
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55095, USA
    Parkinsonism Relat Disord 17:730-6. 2011
    ..Here we investigated the association of PD with interactions between variants of these genes...
  13. doi request reprint Variants in estrogen-related genes and risk of Parkinson's disease
    Sun Ju Chung
    Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
    Mov Disord 26:1234-42. 2011
    ..Our results confirm the association of PRDM2 variants with Parkinson's disease susceptibility, especially in women...
  14. pmc Genomic determinants of motor and cognitive outcomes in Parkinson's disease
    Sun Ju Chung
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Parkinsonism Relat Disord 18:881-6. 2012
    ..Little is known regarding genetic factors associated with motor or cognitive outcomes in Parkinson's disease (PD)...
  15. pmc CYP2C19 variation and citalopram response
    David A Mrazek
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Pharmacogenet Genomics 21:1-9. 2011
    ..Citalopram is metabolized by three CYP enzymes. CYP2C19 and CYP3A4 play a primary role in citalopram metabolism, whereas CYP2D6 plays a secondary role...
  16. doi request reprint Gender differences in the relationship between depressive symptoms and cravings in alcoholism
    Nelli Boykoff
    Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Am J Addict 19:352-6. 2010
    ..78). Further prospective study is encouraged to evaluate whether depressive symptoms and concomitant alcohol cravings in women are a marker for relief cravings and, as such, a target symptom for treatment intervention...
  17. pmc A retrospective study of gender differences in depressive symptoms and risk of relapse in patients with alcohol dependence
    Osama A Abulseoud
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55902, USA
    Am J Addict 22:437-42. 2013
    ..The aim of this study was to investigate potential gender differences in situations associated with heavy alcohol drinking...
  18. doi request reprint Utilization of residential alcoholism treatment in bipolar disorder
    Daniel K Hall-Flavin
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Addict 20:40-4. 2011
    ..Future studies are encouraged to better understand utilization rates of addiction treatment among patients with bipolar disorder and to identify clinical correlates that predispose bipolar women to high-dose drinking. ..
  19. pmc Single versus multiple imputation for genotypic data
    Brooke L Fridley
    Department of Health Sciences Research, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA
    BMC Proc 3:S7. 2009
    ..This limited study involving four regions indicates that, contrary to expectations, multiple imputations may not be necessary...
  20. doi request reprint Interaction of SLC6A4 and DRD2 polymorphisms is associated with a history of delirium tremens
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Addict Biol 15:23-34. 2010
    ..This study provides the first evidence to implicate the interaction between serotonin and dopamine neurotransmission in the etiology of DT. Replication is necessary to verify this potentially important finding...
  21. pmc Sequence variations of the human MPDZ gene and association with alcoholism in subjects with European ancestry
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Alcohol Clin Exp Res 33:712-21. 2009
    ..Mpdz gene variations are known contributors of acute alcohol withdrawal severity and seizures in mice...
  22. pmc Functional role of the polymorphic 647 T/C variant of ENT1 (SLC29A1) and its association with alcohol withdrawal seizures
    Jeong Hyun Kim
    Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
    PLoS ONE 6:e16331. 2011
    ..Interestingly, in humans, the ENT1 (SLC29A1) gene contains a non-synonymous single nucleotide polymorphism (647 T/C; rs45573936) that might be involved in the functional change of ENT1...
  23. pmc Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependence
    Victor M Karpyak
    Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
    Addict Biol 17:798-806. 2012
    ..The statistically significant association of alcohol dependence with genetic variation in the NMDA-dependent AMPA receptor trafficking cascade indicates a need for further investigation of the role of this pathway in alcohol dependence...
  24. pmc Use of the gamma method for self-contained gene-set analysis of SNP data
    Joanna M Biernacka
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Eur J Hum Genet 20:565-71. 2012
    ..We also applied all of the considered GSA methods to data from a pharmacogenomic study of cisplatin, and obtained evidence suggesting that the glutathione metabolism GS is associated with cisplatin drug response...
  25. pmc Common variants in PARK loci and related genes and Parkinson's disease
    Sun Ju Chung
    Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA
    Mov Disord 26:280-8. 2011
    ..Our results confirm the association of MAPT and SNCA genes with PD susceptibility but show limited association of other PARK loci and related genes with PD...
  26. doi request reprint Effect of cytochrome P450 enzyme polymorphisms on pharmacokinetics of venlafaxine
    Donald E McAlpine
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Ther Drug Monit 33:14-20. 2011
    ....
  27. pmc Identification of genes and haplotypes that predict rheumatoid arthritis using random forests
    Rui Tang
    Department of Health Sciences Research, 200 First Street Southwest, Mayo Clinic, Rochester, Minnesota 55905, USA
    BMC Proc 3:S68. 2009
    ..Although RFs are a promising approach for genetic data analysis, extensions beyond simple single-nucleotide polymorphism analyses and modifications to improve computational feasibility are needed...
  28. pmc SNP interaction detection with Random Forests in high-dimensional genetic data
    Stacey J Winham
    Department of Health Sciences Research, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA
    BMC Bioinformatics 13:164. 2012
    ....
  29. pmc FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder
    Katarzyna A Ellsworth
    Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA
    Pharmacogenet Genomics 23:156-66. 2013
    ....
  30. pmc Joint linkage and association analysis for identification of potentially causal polymorphisms in GAW15 data
    Joanna M Biernacka
    Institute of Human Genetics, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK
    BMC Proc 1:S36. 2007
    ..We compare the power of several methods for testing the null hypothesis that association with a particular variant can explain the observed linkage signal, and discuss scenarios under which the various methods may be advantageous...
  31. doi request reprint Pretransplant psychiatric and substance use comorbidity in patients with cholangiocarcinoma who received a liver transplant
    Terry D Schneekloth
    Department of Psychiatry and Psychology, Mayo Clinic Rochester, MN, USA
    Psychosomatics 53:116-22. 2012
    ..We assessed for pretransplant psychopathology and substance use disorders in liver transplant recipients with cholangiocarcinoma to better characterize this patient group...
  32. pmc Identification of gene-gene interaction using principal components
    Jia Li
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Harwick 776, Rochester, Minnesota 55905, USA
    BMC Proc 3:S78. 2009
    ..However, further study is needed to evaluate the power and the feasibility for a whole genome-wide association analysis using the principal components approach...
  33. pmc Gene set analysis of SNP data: benefits, challenges, and future directions
    Brooke L Fridley
    Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Eur J Hum Genet 19:837-43. 2011
    ..This paper provides an overview of GSA, highlighting the key challenges, potential solutions, and directions for ongoing research...
  34. ncbi request reprint Perils and pitfalls of permutation tests for distinguishing the effects of neighbouring polymorphisms
    Joanna M Biernacka
    Department of Medical Genetics, University of Cambridge, Cambridge Institute for Medical Research, Cambridge, UK
    Genet Epidemiol 30:582-9. 2006
    ..2005], which does not rely on haplotyping, and results in correct type 1 errors and potentially high power when assumptions of random mating, Hardy-Weinberg Equilibrium, and multiplicative effects of disease alleles are satisfied...
  35. pmc Gene-environment interactions in genome-wide association studies: current approaches and new directions
    Stacey J Winham
    Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
    J Child Psychol Psychiatry 54:1120-34. 2013
    ....
  36. pmc Linkage and association analysis of GAW15 simulated data: fine-mapping of chromosome 6 region
    Pimphen Charoen
    University of Cambridge, Diabetes and Inflammation Laboratory, Department of Medical Genetics, CIMR, Addenbrookes Hospital, Cambridge, CB2 2XY, UK
    BMC Proc 1:S23. 2007
    ....
  37. ncbi request reprint Using linkage and association to identify and model genetic effects: summary of GAW15 Group 4
    Qiong Yang
    Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Boston, MA 02118, USA
    Genet Epidemiol 31:S34-42. 2007
    ..Finally, modeling the disease using association evidence conditional on linkage may improve understanding of the etiology of disease...
  38. ncbi request reprint Tests for the presence of two linked disease susceptibility genes
    Joanna M Biernacka
    Department of Public Health Sciences, University of Toronto, Toronto, Canada
    Genet Epidemiol 29:389-401. 2005
    ..Power to detect the presence of two linked disease genes increased with the number of affected sib pairs, greater IBD sharing at the two loci, and larger distance between the two loci...
  39. ncbi request reprint Simultaneous localization of two linked disease susceptibility genes
    Joanna M Biernacka
    Department of Public Health Sciences, University of Toronto, Toronto, Canada
    Genet Epidemiol 28:33-47. 2005
    ..Joint localization of two disease genes improves with increased excess allele sharing at the disease gene loci, increased distance between the disease genes, and increased number of affected sib pairs in the sample...