Debra Barton

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. doi Pilot study of Panax quinquefolius (American ginseng) to improve cancer-related fatigue: a randomized, double-blind, dose-finding evaluation: NCCTG trial N03CA
    Debra L Barton
    Mayo Clinic and Mayo Foundation, 200 First Street, SW, Rochester, MN 55905, USA
    Support Care Cancer 18:179-87. 2010
  2. pmc Gabapentin for the management of hot flashes in prostate cancer survivors: a longitudinal continuation Study-NCCTG Trial N00CB
    Amanda R Moraska
    Mayo Clinic Rochester, Rochester, Minnesota 55905, USA
    J Support Oncol 8:128-32. 2010
  3. ncbi Randomized controlled trial to evaluate transdermal testosterone in female cancer survivors with decreased libido; North Central Cancer Treatment Group protocol N02C3
    Debra L Barton
    Department of Medical Oncology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Natl Cancer Inst 99:672-9. 2007
  4. pmc The use of Ginkgo biloba for the prevention of chemotherapy-related cognitive dysfunction in women receiving adjuvant treatment for breast cancer, N00C9
    Debra L Barton
    Mayo Clinic Rochester, Rochester, MN 55905, USA
    Support Care Cancer 21:1185-92. 2013
  5. doi Clinical trials in integrative therapies
    Debra L Barton
    Mayo Clinic Cancer Center, Rochester, MN 55905, USA
    Semin Oncol Nurs 28:10-28. 2012
  6. ncbi Venlafaxine for the control of hot flashes: results of a longitudinal continuation study
    Debra Barton
    Mayo Clinic in Rochester, MN, USA
    Oncol Nurs Forum 29:33-40. 2002
  7. ncbi Can complementary and alternative medicine clinical cancer research be successfully accomplished? The Mayo Clinic-North Central Cancer Treatment Group experience
    Debra L Barton
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Soc Integr Oncol 4:143-52. 2006
  8. pmc A double-blind, placebo-controlled trial of a topical treatment for chemotherapy-induced peripheral neuropathy: NCCTG trial N06CA
    Debra L Barton
    Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN 55905, USA
    Support Care Cancer 19:833-41. 2011
  9. pmc Phase III, placebo-controlled trial of three doses of citalopram for the treatment of hot flashes: NCCTG trial N05C9
    Debra L Barton
    Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 28:3278-83. 2010
  10. ncbi Libido as part of sexuality in female cancer survivors
    Debra Barton
    Mayo Clinic Cancer Center, Rochester, MN, USA
    Oncol Nurs Forum 31:599-609. 2004

Collaborators

Detail Information

Publications51

  1. doi Pilot study of Panax quinquefolius (American ginseng) to improve cancer-related fatigue: a randomized, double-blind, dose-finding evaluation: NCCTG trial N03CA
    Debra L Barton
    Mayo Clinic and Mayo Foundation, 200 First Street, SW, Rochester, MN 55905, USA
    Support Care Cancer 18:179-87. 2010
    ..This pilot trial sought to investigate whether any of three doses of American ginseng (Panax quinquefolius) might help cancer-related fatigue. A secondary aim was to evaluate toxicity...
  2. pmc Gabapentin for the management of hot flashes in prostate cancer survivors: a longitudinal continuation Study-NCCTG Trial N00CB
    Amanda R Moraska
    Mayo Clinic Rochester, Rochester, Minnesota 55905, USA
    J Support Oncol 8:128-32. 2010
    ..These findings suggest that low-dose gabapentin is moderately efficacious for at least 12 weeks of hot flash treatment in men undergoing androgen deprivation therapy for prostate cancer and seems to be well tolerated. (NCT00028572)..
  3. ncbi Randomized controlled trial to evaluate transdermal testosterone in female cancer survivors with decreased libido; North Central Cancer Treatment Group protocol N02C3
    Debra L Barton
    Department of Medical Oncology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Natl Cancer Inst 99:672-9. 2007
    ..Transdermal testosterone therapy has been associated with increased libido among estrogen-replete women who report low libido...
  4. pmc The use of Ginkgo biloba for the prevention of chemotherapy-related cognitive dysfunction in women receiving adjuvant treatment for breast cancer, N00C9
    Debra L Barton
    Mayo Clinic Rochester, Rochester, MN 55905, USA
    Support Care Cancer 21:1185-92. 2013
    ....
  5. doi Clinical trials in integrative therapies
    Debra L Barton
    Mayo Clinic Cancer Center, Rochester, MN 55905, USA
    Semin Oncol Nurs 28:10-28. 2012
    ..To review clinical trials in natural products and mind-body therapies for oncology symptom management, to discuss issues related to developing clinical trials in this area, and outline examples of rigorous and innovative study design...
  6. ncbi Venlafaxine for the control of hot flashes: results of a longitudinal continuation study
    Debra Barton
    Mayo Clinic in Rochester, MN, USA
    Oncol Nurs Forum 29:33-40. 2002
    ..To evaluate the intermediate term efficacy and toxicity of the use of venlafaxine for the control of hot flashes...
  7. ncbi Can complementary and alternative medicine clinical cancer research be successfully accomplished? The Mayo Clinic-North Central Cancer Treatment Group experience
    Debra L Barton
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Soc Integr Oncol 4:143-52. 2006
    ..Well-designed and adequately powered studies can be implemented, and large numbers of patients can be accrued. The resulting research evaluations can be published in peer-reviewed medical journals...
  8. pmc A double-blind, placebo-controlled trial of a topical treatment for chemotherapy-induced peripheral neuropathy: NCCTG trial N06CA
    Debra L Barton
    Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN 55905, USA
    Support Care Cancer 19:833-41. 2011
    ..The purpose of this double-blind randomized placebo-controlled trial was to evaluate a novel compounded topical gel for this problem...
  9. pmc Phase III, placebo-controlled trial of three doses of citalopram for the treatment of hot flashes: NCCTG trial N05C9
    Debra L Barton
    Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 28:3278-83. 2010
    ..Therefore, there is a continued need for rigorous evaluation to identify effective nonhormonal options for hot flash relief...
  10. ncbi Libido as part of sexuality in female cancer survivors
    Debra Barton
    Mayo Clinic Cancer Center, Rochester, MN, USA
    Oncol Nurs Forum 31:599-609. 2004
    ..To present the state of knowledge and a suggested program of research related to one part of sexual functioning in female cancer survivors: libido...
  11. doi Oral agents in cancer treatment: the context for adherence
    Debra Barton
    Oncology, Mayo Clinic, 200 First Street SW, Charlton 6 133, Rochester, MN 55905, USA
    Semin Oncol Nurs 27:104-15. 2011
    ..To review oral agents approved for cancer, discuss their mechanism of action and/or molecular targets, and outline side effects and challenges that impact adherence...
  12. pmc The use of Valeriana officinalis (Valerian) in improving sleep in patients who are undergoing treatment for cancer: a phase III randomized, placebo-controlled, double-blind study (NCCTG Trial, N01C5)
    Debra L Barton
    Mayo Clinic Rochester, Rochester, MN 55905, USA
    J Support Oncol 9:24-31. 2011
    ..However, exploratory analyses revealed improvement in some secondary outcomes, such as fatigue. Further research with valerian exploring physiologic effects in oncology symptom management may be warranted...
  13. ncbi Making sense of the evidence regarding nonhormonal treatments for hot flashes
    Debra Barton
    Clin J Oncol Nurs 8:39-42. 2004
    ..This algorithm includes nonhormonal options of the antidepressants available in addition to gabapentin, an antiseizure medication. A short review of the evidence for possible complementary therapies also is included...
  14. ncbi Phase III comparison of depomedroxyprogesterone acetate to venlafaxine for managing hot flashes: North Central Cancer Treatment Group Trial N99C7
    Charles L Loprinzi
    Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Clin Oncol 24:1409-14. 2006
    ..This current trial compared a single intramuscular dose of medroxyprogesterone acetate (MPA), depot preparation, versus daily oral venlafaxine as treatment for hot flashes...
  15. pmc Newer antidepressants and gabapentin for hot flashes: an individual patient pooled analysis
    Charles L Loprinzi
    Division of Medical Oncology, Mayo Clinic, 200 First St Southwest, Rochester MN 55905, USA
    J Clin Oncol 27:2831-7. 2009
    ..This current project was developed to conduct an individual patient pooled analysis of the data from these published clinical trials...
  16. pmc Phase III, randomized, double-blind, placebo-controlled study of long-acting methylphenidate for cancer-related fatigue: North Central Cancer Treatment Group NCCTG-N05C7 trial
    Amanda R Moraska
    Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 28:3673-9. 2010
    ..Fatigue is one of the most common symptoms experienced by patients with cancer. This trial was developed to evaluate the efficacy of long-acting methylphenidate for improving cancer-related fatigue and to assess its toxicities...
  17. pmc Pilot evaluation of a stellate ganglion block for the treatment of hot flashes
    Deirdre R Pachman
    Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Support Care Cancer 19:941-7. 2011
    ....
  18. ncbi Centrally active nonhormonal hot flash therapies
    Charles L Loprinzi
    Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Am J Med 118:118-23. 2005
    ..The most efficacious and clinically appropriate agents for use are newer antidepressants and gabapentin. Continued evaluation of the efficacy and toxicity of these agents is ongoing...
  19. doi Concerns across the survivorship trajectory: results from a survey of cancer survivors
    Sheryl Ness
    Mayo Clinic College of Medicine, Rochester, MN, USA
    Oncol Nurs Forum 40:35-42. 2013
    ..To evaluate the most prevalent physical, social, emotional, and spiritual concerns of cancer survivors...
  20. ncbi Pilot evaluation of bupropion for the treatment of hot flashes
    Domingo G Perez
    Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Palliat Med 9:631-7. 2006
    ..These data suggest that bupropion should not be further investigated as a remedy for hot flashes...
  21. ncbi Menopausal symptoms following tamoxifen treatment for breast cancer
    Debra L Barton
    Mayo Clinic Cancer Center, Rochester, Minnesota, USA
    Oncology (Williston Park) 22:46-8. 2008
    ..Hot flashes negatively impacted the patient's mood, stress level, sleep, and relationship with her husband. Breathing exercises and pharmacological management with a low-dose antidepressant alleviated the problem...
  22. ncbi Levetiracetam for the treatment of hot flashes: a phase II study
    Susan Thompson
    Division of Medical Oncology, Mayo Clinic College of Medicine, 200 First Street S W, Rochester, MN 55905, USA
    Support Care Cancer 16:75-82. 2008
    ..The objectives of this pilot trial were to assess the potential efficacy and safety of levetiracetam for the treatment of hot flashes, a major cause of morbidity among breast cancer survivors...
  23. doi Chemotherapy-induced peripheral neuropathy: prevention and treatment strategies
    Sherry Wolf
    Department of Medical Oncology, Mayo Clinic, Rochester, MN, USA
    Eur J Cancer 44:1507-15. 2008
    ..Lastly, paclitaxel causes a unique acute pain syndrome which has been hypothesised to be caused by neurologic injury. No drugs, to date, have been proven to prevent this toxicity...
  24. ncbi Pilot evaluation of mirtazapine for the treatment of hot flashes
    Domingo G Perez
    Mayo Clinic, Rochester, Minnesota 55905, USA
    J Support Oncol 2:50-6. 2004
    ....
  25. ncbi Pilot evaluation of citalopram for the relief of hot flashes
    Debra L Barton
    Mayo Clinic, Rochester, Minnesota 55905, USA
    J Support Oncol 1:47-51. 2003
    ..This pilot trial suggests that citalopram may be an effective non-hormonal treatment for hot flashes in women who can tolerate it...
  26. ncbi Efficacy of complementary and alternative medicine therapies in relieving cancer pain: a systematic review
    Aditya Bardia
    Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
    J Clin Oncol 24:5457-64. 2006
    ..This is a systematic review of randomized controlled trials (RCTs) evaluating CAM therapies for cancer-related pain...
  27. doi Symptom management in premenopausal patients with breast cancer
    Charles L Loprinzi
    Department of Medical Oncology, Mayo Clinic, Rochester, MN, USA
    Lancet Oncol 9:993-1001. 2008
    ..Although some effective treatments can counteract symptoms related to cancer or treatments, research is needed to expand evidence-based care in premenopausal survivors of breast cancer...
  28. ncbi Phase III double-blind, randomized, placebo-controlled crossover trial of black cohosh in the management of hot flashes: NCCTG Trial N01CC1
    Barbara A Pockaj
    Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Clin Oncol 24:2836-41. 2006
    ..Hot flashes can cause significant morbidity in postmenopausal women undergoing or finished with breast cancer treatment. Black cohosh has been used to treat hot flashes, but definitive clinical data about efficacy have been equivocal...
  29. ncbi Tamoxifen-associated hot flashes in women
    Domingo G Perez
    Division of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN
    Support Cancer Ther 4:152-6. 2007
    ....
  30. ncbi Depomedroxyprogesterone acetate for hot flashes
    Debra Barton
    Mayo Clinic, Rochester, MN 55905, USA
    J Pain Symptom Manage 24:603-7. 2002
    ..Reported side effects were minimal. This experience suggests that treatment with depomedroxyprogesterone may be an effective and well-tolerated option for the treatment of hot flashes...
  31. ncbi Pilot evaluation of flaxseed for the management of hot flashes
    Sandhya Pruthi
    Division of General Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Soc Integr Oncol 5:106-12. 2007
    ..This study suggests that dietary therapy decreases hot flash activity in women not taking estrogen therapy. This reduction is greater than what would be expected with placebo...
  32. ncbi Pilot evaluation of gabapentin for treating hot flashes
    L Loprinzi
    Division of Medical Oncology, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 77:1159-63. 2002
    ..To obtain pilot prospective data regarding the efficacy and tolerability of gabapentin for alleviating hot flashes...
  33. ncbi Pathophysiology and treatment of hot flashes
    Tait D Shanafelt
    Department of Oncology, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 77:1207-18. 2002
    ..The use of clonidine, methyldopa, and belladonna should be discouraged because of their modest efficacy and adverse effects...
  34. ncbi A critical review of complementary therapies for cancer-related fatigue
    Amit Sood
    Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Integr Cancer Ther 6:8-13. 2007
    ..To review the available literature on the use of complementary and alternative medicine (CAM) treatments for cancer-related fatigue with an aim to develop directions for future research...
  35. ncbi Pilot evaluation of paroxetine for treating hot flashes in men
    Charles L Loprinzi
    Division of Medical Oncology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 79:1247-51. 2004
    ..To provide prospective information on the potential utility of paroxetine for treating hot flashes In men receiving androgen ablation therapy for prostate cancer...
  36. ncbi Phase III trial of gabapentin alone or in conjunction with an antidepressant in the management of hot flashes in women who have inadequate control with an antidepressant alone: NCCTG N03C5
    Charles L Loprinzi
    Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 25:308-12. 2007
    ..No data have been available to address whether the combination of both agents would more effectively alleviate hot flashes, compared with gabapentin alone, in patients with inadequate hot flash control with an antidepressant alone...
  37. ncbi Pilot evaluation of black cohosh for the treatment of hot flashes in women
    Barbara A Pockaj
    Department of Surgery, Mayo Clinic, Scottsdale, Arizona 85259, USA
    Cancer Invest 22:515-21. 2004
    ..Hot flashes cause significant morbidity in postmenopausal women, including women with breast cancer. We undertook a pilot study to estimate the effectiveness of black cohosh to reduce hot flashes...
  38. ncbi Pilot evaluation of citalopram for the treatment of hot flashes in women with inadequate benefit from venlafaxine
    Charles L Loprinzi
    Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Palliat Med 8:924-30. 2005
    ....
  39. doi Newer antidepressants for hot flashes--should their efficacy still be up for debate?
    Charles L Loprinzi
    Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Menopause 16:184-7. 2009
    ..These two studies have repeatedly been put forward as evidence that newer antidepressants are not definitively proven to reduce hot flashes...
  40. ncbi Symptom control trials: a 20-year experience
    Charles L Loprinzi
    Division of Medical Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Support Oncol 5:119-25, 128. 2007
    ....
  41. ncbi Evaluation of shark cartilage in patients with advanced cancer: a North Central Cancer Treatment Group trial
    Charles L Loprinzi
    Department of Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 56301, USA
    Cancer 104:176-82. 2005
    ..Secondary research goals were to evaluate toxicities, tolerability, and quality of life associated with this shark cartilage product...
  42. doi Challenges of oral medications in patients with advanced breast cancer
    Frances M Palmieri
    Breast Clinic and Breast Cancer Program, Mayo Clinic, Jacksonville, FL 32224, USA
    Semin Oncol Nurs 23:S17-22. 2007
    ..To list methods that nurses can use to monitor and ensure compliance with an oral agent for the treatment of metastatic breast cancer...
  43. doi Mayo Clinic and North Central Cancer Treatment Group hot flash studies: a 20-year experience
    Charles L Loprinzi
    Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Menopause 15:655-60. 2008
    ..This project was designed to provide an overview of hot flash studies conducted over the past two decades at the Mayo Clinic and in the North Central Cancer Treatment Group...
  44. ncbi Chemotherapy-induced ovarian failure: manifestations and management
    Julian R Molina
    Department of Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Drug Saf 28:401-16. 2005
    ....
  45. ncbi Acupuncture for hot flashes: a randomized, sham-controlled clinical study
    Ann Vincent
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Menopause 14:45-52. 2007
    ....
  46. ncbi Current management of menopausal symptoms in cancer patients
    Debra L Barton
    Gynecologic Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Oncology (Williston Park) 16:67-72, 74; discussion 75-6, 79-80. 2002
    ..The issue of cognitive dysfunction is also addressed. For most of the problems associated with menopause, viable, effective options are available for cancer survivors...
  47. ncbi Novel approaches to preventing chemotherapy-induced cognitive dysfunction in breast cancer: the art of the possible
    Debra Barton
    Mayo Clinic, Division of Medical Oncology, Rochester, MN 55905, USA
    Clin Breast Cancer 3:S121-7. 2002
    ..Possible anecdotal strategies to consider include hormonal interventions, antioxidants, monoamine oxidase inhibitors, growth factors, dopamine agonists, cholinesterase inhibitors, antiinflammatory agents, and behavioral interventions..
  48. doi Husbands' perspective of living with wives' ovarian cancer
    Julie Ann Ponto
    Graduate Program in Nursing, Winona State University, Mayo Clinic, Division of Nursing Research, MN 55904, USA
    Psychooncology 17:1225-31. 2008
    ..The purpose of this qualitative study was to describe the experience of ovarian cancer from the husband's perspective...
  49. ncbi Use of methylphenidate in patients with cancer
    Amit Sood
    Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
    Am J Hosp Palliat Care 23:35-40. 2006
    ....
  50. ncbi Stellate-ganglion block: a new treatment for hot flushes?
    Charles L Loprinzi
    Lancet Oncol 9:506-7. 2008
  51. ncbi Whose opinion counts?
    Charles L Loprinzi
    J Clin Oncol 24:5183-5. 2006