Karla V Ballman

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc The relationship between six-month progression-free survival and 12-month overall survival end points for phase II trials in patients with glioblastoma multiforme
    Karla V Ballman
    Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Neuro Oncol 9:29-38. 2007
  2. doi request reprint Genetics and genomics: gene expression microarrays
    Karla V Ballman
    Division of Biostatistics, Mayo Clinic, Rochester, MN 55905, USA
    Circulation 118:1593-7. 2008
  3. ncbi request reprint Faster cyclic loess: normalizing RNA arrays via linear models
    Karla V Ballman
    Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Bioinformatics 20:2778-86. 2004
  4. pmc Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model
    Gaspar J Kitange
    Department of Radiation Oncology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    J Neurooncol 92:23-31. 2009
  5. pmc Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models
    Ling Cen
    Department of Radiation Oncology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Neuro Oncol 15:735-46. 2013
  6. doi request reprint CHOD/BVAM chemotherapy and whole-brain radiotherapy for newly diagnosed primary central nervous system lymphoma
    Nadia N Laack
    Department of Radiation Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Int J Radiat Oncol Biol Phys 81:476-82. 2011
  7. pmc Expression of CD74 in high grade gliomas: a potential role in temozolomide resistance
    Gaspar J Kitange
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    J Neurooncol 100:177-86. 2010
  8. ncbi request reprint Phase III trial of carmustine and cisplatin compared with carmustine alone and standard radiation therapy or accelerated radiation therapy in patients with glioblastoma multiforme: North Central Cancer Treatment Group 93-72-52 and Southwest Oncology Group
    Jan C Buckner
    Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Clin Oncol 24:3871-9. 2006
  9. pmc Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial
    Christopher L Corless
    Christopher L Corless, Violetta Kolesnikova, Charles D Blanke, Michael C Heinrich, Oregon Health and Science University, Portland, OR Karla V Ballman, Mayo Clinic, Rochester, MN Cristina R Antonescu and Ronald P DeMatteo, Memorial Sloan Kettering Cancer Center Robert G Maki, Mt Sinai School of Medicine, New York, NY Peter W T Pisters and Shreyaskumar Patel, University of Texas MD Anderson Cancer Center, Houston, TX Martin E Blackstein, Mount Sinai Hospital, Toronto, Ontario, Canada George D Demetri, Dana Farber Cancer Institute, Boston, MA Margaret von Mehren, Fox Chase Cancer Institute, Philadelphia, PA Martin D McCarter, University of Colorado School of Medicine, Aurora, CO and Kouros Owzar, Duke University School of Medicine, Durham, NC
    J Clin Oncol 32:1563-70. 2014
  10. ncbi request reprint How much of the increased incidence of heart failure in rheumatoid arthritis is attributable to traditional cardiovascular risk factors and ischemic heart disease?
    Cynthia S Crowson
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Arthritis Rheum 52:3039-44. 2005

Detail Information

Publications80

  1. pmc The relationship between six-month progression-free survival and 12-month overall survival end points for phase II trials in patients with glioblastoma multiforme
    Karla V Ballman
    Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Neuro Oncol 9:29-38. 2007
    ..Finally, there was a strong association between progression-free survival status and overall survival. PFS6 seems to be a reasonable end point for phase II trials in patients with recurrent glioblastoma...
  2. doi request reprint Genetics and genomics: gene expression microarrays
    Karla V Ballman
    Division of Biostatistics, Mayo Clinic, Rochester, MN 55905, USA
    Circulation 118:1593-7. 2008
  3. ncbi request reprint Faster cyclic loess: normalizing RNA arrays via linear models
    Karla V Ballman
    Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Bioinformatics 20:2778-86. 2004
    ..Our goal was to develop a normalization technique that yields results similar to cyclic loess normalization and with speed comparable to quantile normalization...
  4. pmc Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model
    Gaspar J Kitange
    Department of Radiation Oncology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    J Neurooncol 92:23-31. 2009
    ..These data highlight one potential limitation of the evaluation of MGMT methylation by MS-PCR assay and suggest that more detailed evaluation of methylation at individual CpG sites relative to TMZ response may be worth pursuing...
  5. pmc Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models
    Ling Cen
    Department of Radiation Oncology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Neuro Oncol 15:735-46. 2013
    ..Temozolomide (TMZ) is important chemotherapy for glioblastoma multiforme (GBM), but the optimal dosing schedule is unclear...
  6. doi request reprint CHOD/BVAM chemotherapy and whole-brain radiotherapy for newly diagnosed primary central nervous system lymphoma
    Nadia N Laack
    Department of Radiation Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    Int J Radiat Oncol Biol Phys 81:476-82. 2011
    ....
  7. pmc Expression of CD74 in high grade gliomas: a potential role in temozolomide resistance
    Gaspar J Kitange
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    J Neurooncol 100:177-86. 2010
    ..Collectively, these findings suggest that CD74 is expressed in a subset of high grade gliomas and may contribute to TMZ resistance...
  8. ncbi request reprint Phase III trial of carmustine and cisplatin compared with carmustine alone and standard radiation therapy or accelerated radiation therapy in patients with glioblastoma multiforme: North Central Cancer Treatment Group 93-72-52 and Southwest Oncology Group
    Jan C Buckner
    Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Clin Oncol 24:3871-9. 2006
    ....
  9. pmc Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial
    Christopher L Corless
    Christopher L Corless, Violetta Kolesnikova, Charles D Blanke, Michael C Heinrich, Oregon Health and Science University, Portland, OR Karla V Ballman, Mayo Clinic, Rochester, MN Cristina R Antonescu and Ronald P DeMatteo, Memorial Sloan Kettering Cancer Center Robert G Maki, Mt Sinai School of Medicine, New York, NY Peter W T Pisters and Shreyaskumar Patel, University of Texas MD Anderson Cancer Center, Houston, TX Martin E Blackstein, Mount Sinai Hospital, Toronto, Ontario, Canada George D Demetri, Dana Farber Cancer Institute, Boston, MA Margaret von Mehren, Fox Chase Cancer Institute, Philadelphia, PA Martin D McCarter, University of Colorado School of Medicine, Aurora, CO and Kouros Owzar, Duke University School of Medicine, Durham, NC
    J Clin Oncol 32:1563-70. 2014
    ..We sought to determine the pathologic and molecular factors associated with patient outcome...
  10. ncbi request reprint How much of the increased incidence of heart failure in rheumatoid arthritis is attributable to traditional cardiovascular risk factors and ischemic heart disease?
    Cynthia S Crowson
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Arthritis Rheum 52:3039-44. 2005
    ....
  11. pmc Effects of the 5 alpha-reductase inhibitor dutasteride on gene expression in prostate cancer xenografts
    Lucy J Schmidt
    Department of Urology Research, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Prostate 69:1730-43. 2009
    ..In this study, we sought to determine how dutasteride is functioning at the molecular level, using a prostate cancer xenograft model...
  12. ncbi request reprint Ischemic stroke after heart failure: a community-based study
    Brandi J Witt
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine and Mayo Foundation, Rochester, MN, USA
    Am Heart J 152:102-9. 2006
    ..Although HF remains a highly fatal disease, the excess mortality imparted from stroke is unknown...
  13. ncbi request reprint Contribution of congestive heart failure and ischemic heart disease to excess mortality in rheumatoid arthritis
    Paulo J Nicola
    Dept of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Arthritis Rheum 54:60-7. 2006
    ....
  14. pmc A tissue biomarker panel predicting systemic progression after PSA recurrence post-definitive prostate cancer therapy
    Tohru Nakagawa
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America
    PLoS ONE 3:e2318. 2008
    ..We hypothesized that an expression biomarker panel can predict which men with a rising PSA would benefit from further therapy...
  15. pmc Characterization and gene expression profiling in glioma cell lines with deletion of chromosome 19 before and after microcell-mediated restoration of normal human chromosome 19
    Kristen L Drucker
    Department of Laboratory Medicine and Pathology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Genes Chromosomes Cancer 48:854-64. 2009
    ..This suggests that one or more of these candidates may play a role in glioma formation or progression...
  16. doi request reprint Phase II evaluation of gefitinib in patients with newly diagnosed Grade 4 astrocytoma: Mayo/North Central Cancer Treatment Group Study N0074
    Joon H Uhm
    Division of Neuro Oncology, Department of Neurology, Mayo Clinic Rochester, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 80:347-53. 2011
    ..In the current study, we evaluated gefitinib, a potent EGFR inhibitor, in the treatment of adults with newly diagnosed GBM...
  17. ncbi request reprint Prospective study of quality of life in adults with newly diagnosed high-grade gliomas
    Paul D Brown
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    J Neurooncol 76:283-91. 2006
    ..To assess baseline quality of life (QOL) and its prognostic importance for adults with newly diagnosed high-grade gliomas, we analyzed QOL and outcome data prospectively collected in three phase II high-grade glioma protocols...
  18. ncbi request reprint A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma
    Robert B Jenkins
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Cancer Res 66:9852-61. 2006
    ..Like combined 1p/19q deletion, the 1;19 translocation is associated with superior OS and progression-free survival in low-grade glioma patients...
  19. ncbi request reprint Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: results of North Central Cancer Treatment Group protocol N0177
    Sunil Krishnan
    Department of Radiation Oncology, Mayo Clinic College of Medicine, Rochester, MN, USA
    Int J Radiat Oncol Biol Phys 65:1192-9. 2006
    ..To evaluate the toxicity and maximum tolerated dose (MTD) of erlotinib plus radiation therapy (RT) in patients with glioblastoma multiforme (GBM) in a multicenter phase I trial...
  20. ncbi request reprint Cardiovascular death in rheumatoid arthritis: a population-based study
    Hilal Maradit-Kremers
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Arthritis Rheum 52:722-32. 2005
    ..To determine whether systemic inflammation confers any additional risk for cardiovascular death among patients with rheumatoid arthritis (RA), after adjusting for traditional cardiovascular risk factors and comorbidities...
  21. pmc Androgen modulation of coregulator expression in prostate cancer cells
    Hannelore V Heemers
    Departments of Urology Research Biochemistry and Molecular Biology, Mayo Clinic, 200 First Street Southwest, Rochester, Minnesota 55905
    Mol Endocrinol 23:572-83. 2009
    ....
  22. pmc Long-term results of adjuvant imatinib mesylate in localized, high-risk, primary gastrointestinal stromal tumor: ACOSOG Z9000 (Alliance) intergroup phase 2 trial
    Ronald P Dematteo
    Memorial Sloan Kettering Cancer Center, New York, NY Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN Oregon Health Sciences University, Portland, OR Fox Chase Cancer Center, Philadelphia, PA University of Colorado School of Medicine, Aurora, CO Stanford University School of Medicine, Stanford CA Mt Sinai School of Medicine, New York, NY University of Texas MD Anderson Cancer Center, Houston, TX Dana Farber Cancer Institute, Boston, MA and Alliance Statistics and Data Center, Duke University, Durham, NC
    Ann Surg 258:422-9. 2013
    ..To conduct the first adjuvant trial of imatinib mesylate for treatment of gastrointestinal stromal tumor (GIST)...
  23. ncbi request reprint A prospective study of quality of life in adults with newly diagnosed high-grade gliomas: the impact of the extent of resection on quality of life and survival
    Paul D Brown
    Division of Radiation Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Neurosurgery 57:495-504; discussion 495-504. 2005
    ..To describe the quality of life (QOL) over time for adults with newly diagnosed high-grade gliomas and to examine the relationship between QOL and outcome data collected in three prospective cooperative group clinical trials...
  24. doi request reprint A prospective study of quality of life in adults with newly diagnosed high-grade gliomas: comparison of patient and caregiver ratings of quality of life
    Paul D Brown
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Clin Oncol 31:163-8. 2008
    ..To examine whether a caregiver can provide reliable proxy quality of life (QOL) ratings of their adult significant other with a newly diagnosed high-grade glioma...
  25. pmc Validation of single-item linear analog scale assessment of quality of life in neuro-oncology patients
    Dona E C Locke
    Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, Arizona 85259, USA
    J Pain Symptom Manage 34:628-38. 2007
    ..The data suggest that the single-item LASA scales are valid for assessing QOL of cancer patients and are an appropriate alternative when a shorter instrument is warranted...
  26. ncbi request reprint Glucocorticoids and cardiovascular events in rheumatoid arthritis: a population-based cohort study
    John M Davis
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Arthritis Rheum 56:820-30. 2007
    ..To determine the relationship between glucocorticoid exposure and cardiovascular (CV) events in patients with rheumatoid arthritis (RA)...
  27. ncbi request reprint Increased unrecognized coronary heart disease and sudden deaths in rheumatoid arthritis: a population-based cohort study
    Hilal Maradit-Kremers
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Arthritis Rheum 52:402-11. 2005
    ....
  28. ncbi request reprint Ototoxicity of cisplatin plus standard radiation therapy vs. accelerated radiation therapy in glioblastoma patients
    Nicole E Marshall
    Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Neurooncol 77:315-20. 2006
    ..To assess the effect of cisplatin (CDDP) plus concurrent radiation therapy on hearing loss...
  29. ncbi request reprint The incidence of stroke after myocardial infarction: a meta-analysis
    Brandi J Witt
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minn 55905, USA
    Am J Med 119:354.e1-9. 2006
    ..We reviewed cohort studies reporting the incidence of stroke after MI to better define the risk of ischemic stroke in an unselected population...
  30. ncbi request reprint Detrimental effects of tumor progression on cognitive function of patients with high-grade glioma
    Paul D Brown
    Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 24:5427-33. 2006
    ..To assess the cognitive performance of high-grade glioma patients, prospectively collected cognitive performance data were analyzed...
  31. ncbi request reprint The risk of congestive heart failure in rheumatoid arthritis: a population-based study over 46 years
    Paulo J Nicola
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Arthritis Rheum 52:412-20. 2005
    ..We examined the risk and determinants of congestive heart failure (CHF) in patients with RA...
  32. ncbi request reprint Comparative efficacy of monophasic and biphasic waveforms for transthoracic cardioversion of atrial fibrillation and atrial flutter
    Osnat T Gurevitz
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
    Am Heart J 149:316-21. 2005
    ..This study sought to determine the relative efficacy of biphasic waveforms compared with monophasic waveforms in the treatment of atrial arrhythmias...
  33. ncbi request reprint Joint estimation of calibration and expression for high-density oligonucleotide arrays
    Ann L Oberg
    Division of Biostatistics, Department of Health Sciences Research, Mayo Clinic College of Medicine 200 First Street SW, Rochester, MN 55905, USA
    Bioinformatics 22:2381-7. 2006
    ..The need for normalization in microarray experiments has been well documented in the literature. Currently, many analysis methods treat normalization and analysis as a series of steps, with summarized data carried forward to the next step...
  34. ncbi request reprint The incidence of ischemic stroke in chronic heart failure: a meta-analysis
    Brandi J Witt
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine and Mayo Foundation, Rochester, Minnesota 55905, USA
    J Card Fail 13:489-96. 2007
    ..We will summarize the ischemic stroke rate at various time points during follow-up among adults with chronic heart failure...
  35. ncbi request reprint Prostate cancer cells use genetic and epigenetic mechanisms for progression to androgen independence
    Horacio Murillo
    Urology Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Genes Chromosomes Cancer 45:702-16. 2006
    ..This article contains Supplementary Material available at http://www.interscience.wiley.com/jpages/1045-2257/suppmat...
  36. ncbi request reprint Prognosis in patients with anaplastic oligoastrocytoma is associated with histologic grade
    Jan C Buckner
    Division of Medical Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Neurooncol 84:279-86. 2007
    ..Anaplastic oligoastrocytomas (AOA) are relatively uncommon high-grade gliomas. While oligodendroglial elements are thought to be associated with better outcomes, the magnitude of the difference is not clear...
  37. ncbi request reprint Long-term prognosis of inducible ventricular flutter: not an innocent finding
    Osnat Gurevitz
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Am Heart J 147:649-54. 2004
    ..The prognostic significance of ventricular flutter (VFL) induced during programmed electrical stimulation (PES) is currently unknown...
  38. ncbi request reprint Risk factor implications of incidentally discovered uncomplicated bundle branch block
    Wayne L Miller
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Mayo Clin Proc 80:1585-90. 2005
    ..To evaluate the long-term outcome of a community-based patient population with incidentally discovered asymptomatic and uncomplicated bundle branch block (BBB)...
  39. ncbi request reprint Validation of a genomic classifier that predicts metastasis following radical prostatectomy in an at risk patient population
    R Jeffrey Karnes
    Department of Urology, Mayo Clinic, Rochester, Minnesota Electronic address
    J Urol 190:2047-53. 2013
    ..We report a validation study of a genomic classifier that predicts metastasis after radical prostatectomy in a high risk population...
  40. ncbi request reprint Whole-brain radiotherapy and high-dose methylprednisolone for elderly patients with primary central nervous system lymphoma: Results of North Central Cancer Treatment Group (NCCTG) 96-73-51
    Nadia N Laack
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 65:1429-39. 2006
    ..The aim of this study was to evaluate the efficacy, toxicity, and survival of whole-brain radiotherapy-treated (WBRT) and high-dose methylprednisolone (HDMP)-treated in elderly patients with primary central nervous system lymphoma (PCNSL)...
  41. ncbi request reprint Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response
    Jann N Sarkaria
    Department of Radiation Oncology, Laboratory Medicine and Pathology, and Biostatistics, Mayo Clinic, Rochester, Minnesota, USA
    Clin Cancer Res 12:2264-71. 2006
    ..The intent of the current study was to address this relationship using several EGFR-amplified glioblastoma xenografts in an orthotopic athymic mouse model...
  42. ncbi request reprint Inhibition of fatty acid synthase activity in prostate cancer cells by dutasteride
    Lucy J Schmidt
    Department of Urology Research, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Prostate 67:1111-20. 2007
    ....
  43. pmc Validation of neuroradiologic response assessment in gliomas: measurement by RECIST, two-dimensional, computer-assisted tumor area, and computer-assisted tumor volume methods
    Evanthia Galanis
    Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Neuro Oncol 8:156-65. 2006
    ....
  44. ncbi request reprint Clinical predictors of exercise capacity 1 year after cardiac transplantation
    Tat Chi Leung
    Division of Cardiovascular Disease, Mayo Clinic and Foundation, Rochester, Minnesota, USA
    J Heart Lung Transplant 22:16-27. 2003
    ..However, clinical variables predictive of post-transplant exercise capacity have not been well defined. The objective of the present study was to identify clinical features predictive of post-transplant exercise capacity...
  45. pmc Effect of body mass index on tumor characteristics and disease-free survival in patients from the HER2-positive adjuvant trastuzumab trial N9831
    Jennifer A Crozier
    Department of Internal Medicine, Mayo Clinic, Jacksonville, Florida 32224, USA
    Cancer 119:2447-54. 2013
    ..The authors hypothesized that there would be a correlation between BMI and clinical outcome in patients with early stage, human epidermal receptor 2 (HER2)-positive breast cancer enrolled in the N9831 adjuvant trial...
  46. ncbi request reprint Atrial fibrillation after surgical correction of mitral regurgitation in sinus rhythm: incidence, outcome, and determinants
    Steven J Kernis
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
    Circulation 110:2320-5. 2004
    ..The incidence, determinants, and outcome of postoperative atrial fibrillation (AF) after surgery for mitral regurgitation (MR) are poorly defined but may have important implications for timing of mitral valve surgery...
  47. ncbi request reprint Polymorphisms in GLTSCR1 and ERCC2 are associated with the development of oligodendrogliomas
    Ping Yang
    Department of Health Sciences Research, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    Cancer 103:2363-72. 2005
    ..The authors have previously described a 150-kilobase minimal deletion region in gliomas that maps to 19q13.33 and contains 3 novel candidate genes (GLTSCR1, EHD2, and GLTSCR2)...
  48. ncbi request reprint Current strategies in treatment of oligodendroglioma: evolution of molecular signatures of response
    Kurt A Jaeckle
    Mayo Clinic, Rochester, NY, USA
    J Clin Oncol 24:1246-52. 2006
    ....
  49. ncbi request reprint A historical prospective cohort study of carotid artery stenosis after radiotherapy for head and neck malignancies
    Paul D Brown
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 63:1361-7. 2005
    ..To determine carotid artery stenosis incidence after radiotherapy for head-and-neck neoplasms...
  50. ncbi request reprint Discrepancies between the upper limit of vulnerability and defibrillation threshold: prevalence and clinical predictors
    Osnat T Gurevitz
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    J Cardiovasc Electrophysiol 14:728-32. 2003
    ..Significant discrepancies between ULV and DFT are infrequent. The aim of this study was to characterize patients with such discrepancies...
  51. ncbi request reprint Gender differences in C-reactive protein concentrations-confirmation with two sensitive methods
    Joseph P McConnell
    Department of Laboratory, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Clin Chem Lab Med 40:56-9. 2002
    ..0001), was independent of age differences as assessed by multiple regression analysis. The observed gender differences have important implications for the establishment of cut-off points for cardiovascular risk stratification...
  52. pmc Phase II NCCTG trial of RT + irinotecan and adjuvant BCNU plus irinotecan for newly diagnosed GBM
    Kurt A Jaeckle
    Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, FL 32224, USA
    J Neurooncol 99:73-80. 2010
    ..This regimen was not significantly active and radiosensitization was not observed. Non-EIAC patients with UGT1A1*28 variant alleles appear particularly sensitive to toxicity from irinotecan...
  53. ncbi request reprint B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma
    Scott E Strome
    Department of Otolaryngology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Cancer Res 63:6501-5. 2003
    ..These data support B7-H1 blockade as a new approach to enhance the efficacy of T-cell immunotherapy...
  54. pmc Usefulness of immunosuppression for giant cell myocarditis
    Leslie T Cooper
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA
    Am J Cardiol 102:1535-9. 2008
    ..Additionally, withdrawal of immunosuppression can be associated with fatal GCM recurrence...
  55. ncbi request reprint Partial normalization of the heart rate response to exercise after cardiac transplantation: frequency and relationship to exercise capacity
    Ray W Squires
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 77:1295-300. 2002
    ..To determine the frequency of partial normalization of the heart rate response to graded exercise and its relationship to exercise capacity in cardiac transplant recipients...
  56. pmc P-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response
    Andrea K McCollum
    Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Cancer Res 68:7419-27. 2008
    ..Taken together, our results indicate that targeting of Hsp27 and Hsp70 should be exploited to increase the clinical efficacy of Hsp90-directed therapy...
  57. ncbi request reprint Elevated expressions of osteopontin and tenascin C in ascending aortic aneurysms are associated with trileaflet aortic valves as compared with bicuspid aortic valves
    Ramanath Majumdar
    Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN 55905, USA
    Cardiovasc Pathol 16:144-50. 2007
    ..The objective of this investigation was to compare the patterns of gene expression in aortas between TAV and BAV patients with the aim of identifying markers for AscAAs...
  58. ncbi request reprint Prognostic importance of low body mass index in relation to cardiovascular mortality in rheumatoid arthritis
    Hilal Maradit Kremers
    Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Arthritis Rheum 50:3450-7. 2004
    ..This study compared the effect of BMI on cardiovascular mortality in a population-based cohort of subjects with RA with that in a cohort of individuals without RA from the same population...
  59. doi request reprint Cancer registries: a novel alternative to long-term clinical trial follow-up based on results of a comparative study
    Qian Shi
    Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN 55905, USA
    Clin Trials 7:686-95. 2010
    ..Data collection and review were identified as major contributors to the cost of randomized clinical trials (RCTs)...
  60. pmc Evaluation of the value of attribution in the interpretation of adverse event data: a North Central Cancer Treatment Group and American College of Surgeons Oncology Group investigation
    Shauna L Hillman
    Mayo Clinic, Rochester, MN 55905, USA
    J Clin Oncol 28:3002-7. 2010
    ..In March 1998, Common Toxicity Criteria (CTC) version 2.0 introduced the collection of attribution of adverse events (AEs) to study drug. We investigate whether attribution adds value to the interpretation of AE data...
  61. ncbi request reprint A prospective, case-control study of tobacco dependence in thromboangiitis obliterans (Buerger's Disease)
    Leslie T Cooper
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
    Angiology 57:73-8. 2006
    ..03). In contrast to case reports of extreme tobacco dependence in the TAO population, the degree of tobacco dependence in subjects with TAO is similar to that in subjects with CAD...
  62. ncbi request reprint A comparison of surgical resection and stereotactic radiosurgery in the treatment of solitary brain metastases
    BRIAN PATRICK O'NEILL
    Department of Neurology, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 55:1169-76. 2003
    ..To determine whether neurosurgery (NS) or stereotactic radiosurgery (RS) provided better local tumor control and enhanced patient survival...
  63. ncbi request reprint Cognitive function after radiotherapy for supratentorial low-grade glioma: a North Central Cancer Treatment Group prospective study
    Nadia N Laack
    Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Int J Radiat Oncol Biol Phys 63:1175-83. 2005
    ..To evaluate the effects of cranial radiotherapy (RT) on cognitive function in patients with supratentorial low-grade glioma...
  64. ncbi request reprint PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer
    Donkena Krishna Vanaja
    Department of Urology, Mayo Clinic Foundation, Rochester, Minnesota 55905, USA
    Clin Cancer Res 12:1128-36. 2006
    ..We analyzed the expression of genes to identify reliable molecular markers in the diagnosis and progression of prostate cancer...
  65. ncbi request reprint Functional gene expression analysis of clonal plasma cells identifies a unique molecular profile for light chain amyloidosis
    Roshini S Abraham
    Division of Hematology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Blood 105:794-803. 2005
    ..This study provides new insight into the molecular profile of clonal plasma cells and its functional relevance in the pathogenesis of light chain amyloidosis...
  66. ncbi request reprint Hormone replacement therapy and risk of acute myocardial infarction in postmenopausal women with diabetes mellitus
    Apoor S Gami
    Department of Internal Medicine, The Mayo Alliance for Clinical Trials, Rochester, Minnesota 55905, USA
    Am J Cardiol 91:1275-7. 2003
  67. pmc Obstructive sleep apnea and the risk of sudden cardiac death: a longitudinal study of 10,701 adults
    Apoor S Gami
    Section of Electrophysiology and Pacing, Midwest Heart Specialists Advocate Medical Group, Elmhurst, Illinois, USA
    J Am Coll Cardiol 62:610-6. 2013
    ..This study sought to identify the risk of sudden cardiac death (SCD) associated with obstructive sleep apnea (OSA)...
  68. ncbi request reprint Frequency of development of idiopathic dilated cardiomyopathy among relatives of patients with idiopathic dilated cardiomyopathy
    Virginia V Michels
    Department of Medical Genetics, Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA
    Am J Cardiol 91:1389-92. 2003
  69. ncbi request reprint Early effects of pharmacological androgen deprivation in human prostate cancer
    Maria Mercader
    Department of Urology, Mayo Clinic, Rochester, MN 55905, USA
    BJU Int 99:60-7. 2007
    ....
  70. ncbi request reprint Long-term outcomes of out-of-hospital cardiac arrest after successful early defibrillation
    T Jared Bunch
    Department of Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
    N Engl J Med 348:2626-33. 2003
    ..Programs focusing on early defibrillation have improved the rate of survival to hospital discharge. We conducted a population-based analysis of the long-term outcome and quality of life of survivors...
  71. ncbi request reprint Early-onset peripheral arterial occlusive disease: clinical features and determinants of disease severity and location
    Simone Barretto
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Vasc Med 8:95-100. 2003
    ..Low HDL-cholesterol and female sex were associated with disease severity. An aggressive approach to diagnosis and treatment may be warranted as atherosclerosis in other arterial beds was prevalent in half of the patients...
  72. ncbi request reprint Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid
    Emmanouil S Brilakis
    Division of Cardiovascular Diseases, Department of Internal Medicine, W16 Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Atherosclerosis 168:315-22. 2003
    ..On multivariate analysis, the MTRR genotypes were not associated with serum homocysteine or with significant CAD...
  73. ncbi request reprint Obstructive sleep apnea and the recurrence of atrial fibrillation
    Ravi Kanagala
    Mayo Clinic, 200 First St SW, Rochester, Minn 55905, USA
    Circulation 107:2589-94. 2003
    ..We tested the hypothesis that patients with untreated obstructive sleep apnea (OSA) would be at increased risk for recurrence of atrial fibrillation (AF) after cardioversion...
  74. ncbi request reprint Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma
    Christopher E Pelloski
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 25:2288-94. 2007
    ..We sought to evaluate the clinical significance of GBM subtypes as defined by EGFRvIII status...
  75. ncbi request reprint Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease
    Ilan S Weisberg
    Department of Human Genetics, McGill University Health Center Montreal Children s Hospital, 4060 Ste Catherine West, Room 200, Montreal, Canada H3Z 2Z3
    Atherosclerosis 167:205-14. 2003
    ....
  76. ncbi request reprint Long-term survival and amputation risk in thromboangiitis obliterans (Buerger's disease)
    Leslie T Cooper
    J Am Coll Cardiol 44:2410-1. 2004
  77. ncbi request reprint The utility of positron emission tomography in staging of potentially operable carcinoma of the thoracic esophagus: results of the American College of Surgeons Oncology Group Z0060 trial
    Bryan F Meyers
    Department of Surgery, Washington University School of Medicine, St Louis, MO
    J Thorac Cardiovasc Surg 133:738-45. 2007
    ....
  78. ncbi request reprint Age dependence of the influence of methylenetetrahydrofolate reductase genotype on plasma homocysteine level
    Loretta D Spotila
    Department of Bioscience and Biotechnology, College of Arts and Sciences, Drexel University, Philadelphia, PA, USA
    Am J Epidemiol 158:871-7. 2003
    ..Failure to examine younger patients separately may explain why some studies have found no association between the genotype and cardiovascular disease...
  79. ncbi request reprint Long-term outcome of patients who received implantable cardioverter defibrillators for stable ventricular tachycardia
    Michael Glikson
    Sheba Medical Center, Tel Hashomer, Israel
    J Cardiovasc Electrophysiol 15:658-64. 2004
    ..The goal of this study was to estimate future risk of unstable ventricular arrhythmias in patients who received ICDs for stable VT...