Research Topics
Species | S AminSummaryAffiliation: Mayo Clinic Country: USA Publications
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Detail Information
Publications
Mechanical factors and bone health: effects of weightlessness and neurologic injuryShreyasee Amin
Division of Rheumatology, College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Curr Rheumatol Rep 12:170-6. 2010..It also discusses the potential mechanisms through which mechanical stimuli are postulated to act on bone tissue...
Osteoporosis in menS Amin
Division of Rheumatology, Mayo Clinic, Rochester, Minnesota, USA
Rheum Dis Clin North Am 27:19-47. 2001..The efficacy of drug therapies for osteoporosis in men requires greater attention. Currently, a large multicenter study is underway in the United States and should provide much needed insight into the epidemiology of osteoporosis in men...
Association of hip strength estimates by finite-element analysis with fractures in women and menShreyasee Amin
Division of Rheumatology, Department of Internal Medicine, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
J Bone Miner Res 26:1593-600. 2011..Furthermore, an estimated hip strength below 3000 N may represent a critical level of systemic skeletal fragility in both sexes that warrants further investigation...
High serum IGFBP-2 is predictive of increased bone turnover in aging men and womenShreyasee Amin
Division of Rheumatology, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
J Bone Miner Res 22:799-807. 2007..Studying an age-stratified community-based sample of 344 men and 276 women, IGFBP-2 was the strongest predictor of increased bone resorption among the IGF/IGFBPs studied...
Estradiol, testosterone, and the risk for hip fractures in elderly men from the Framingham StudyShreyasee Amin
Boston University Clinical Epidemiology Research and Training Unit, Department of Medicine, Boston University School of Medicine, Boston, Mass, USA
Am J Med 119:426-33. 2006..We examined whether low estradiol increases the risk for future hip fracture among men and explored whether testosterone levels influence this risk...
Quadriceps strength and the risk of cartilage loss and symptom progression in knee osteoarthritisShreyasee Amin
College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Arthritis Rheum 60:189-98. 2009..To determine the effect of quadriceps strength in individuals with knee osteoarthritis (OA) on loss of cartilage at the tibiofemoral and patellofemoral joints (assessed by magnetic resonance imaging [MRI]) and on knee pain and function...
The relationship between cartilage loss on magnetic resonance imaging and radiographic progression in men and women with knee osteoarthritisShreyasee Amin
Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Arthritis Rheum 52:3152-9. 2005....
Male osteoporosis: epidemiology and pathophysiologyShreyasee Amin
Division of Rheumatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Curr Osteoporos Rep 1:71-7. 2003....
Occupation-related squatting, kneeling, and heavy lifting and the knee joint: a magnetic resonance imaging-based study in menShreyasee Amin
College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
J Rheumatol 35:1645-9. 2008....
Knee adduction moment and development of chronic knee pain in eldersShreyasee Amin
Division of Rheumatoilogy, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
Arthritis Rheum 51:371-6. 2004..To determine whether the adduction moment at the knee during locomotor activity contributes to the development of future chronic knee pain...
A potentially deleterious role of IGFBP-2 on bone density in aging men and womenShreyasee Amin
Division of Rheumatology, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
J Bone Miner Res 19:1075-83. 2004..IGFBP-2, which increases with age in both men and women, was the strongest, most consistent predictor of BMD among the IGF/IGFBPs studied...
Pregnancy and rheumatoid arthritis: insights into the immunology of fetal tolerance and control of autoimmunityShreyasee Amin
Division of Rheumatology, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Curr Rheumatol Rep 13:449-55. 2011....
Complete anterior cruciate ligament tear and the risk for cartilage loss and progression of symptoms in men and women with knee osteoarthritisS Amin
Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN 55905, United States
Osteoarthritis Cartilage 16:897-902. 2008....
Cigarette smoking and the risk for cartilage loss and knee pain in men with knee osteoarthritisS Amin
Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Ann Rheum Dis 66:18-22. 2007..To examine the effects of smoking on cartilage loss and pain at the knee in individuals with knee osteoarthritis...
Determinants of forearm strength in postmenopausal womenL J Melton
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, 200 First Street Southwest, Rochester, MN, 55905, USA
Osteoporos Int 22:3047-54. 2011..The specific formula for this bone strength surrogate (-555.2 + 8.1 × [trabecular vBMD] + 19.6 × [cortical area] + 4.2 × [total cross-sectional area]) should be validated and tested in fracture risk assessment...
Change in joint space width: hyaline articular cartilage loss or alteration in meniscus?D J Hunter
Boston University Clinical Epidemiology Research and Training Unit, Arthritis Center, and Boston Medical Center, Boston, Massachusetts 02118, USA
Arthritis Rheum 54:2488-95. 2006..To explore the relative contribution of hyaline cartilage morphologic features and the meniscus to the radiographic joint space...
Sclerostin levels during growth in childrenS Kirmani
Endocrine Research Unit, Guggenheim 7 11, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Osteoporos Int 23:1123-30. 2012..Serum sclerostin levels are associated with cortical porosity, suggesting that changes in sclerostin production during growth may play a role in defining cortical structure...
Trabecular bone deficits among Vietnamese immigrantsL J Melton
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA
Osteoporos Int 22:1627-31. 2011....
Assessing forearm fracture risk in postmenopausal womenL J Melton
Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA
Osteoporos Int 21:1161-9. 2010....
Relationship of femoral neck areal bone mineral density to volumetric bone mineral density, bone size, and femoral strength in men and womenB Srinivasan
Endocrine Research Unit, Mayo Clinic, Guggenheim 7, 200 First Street SW, Rochester, MN 55905, USA
Osteoporos Int 23:155-62. 2012....
The association of meniscal pathologic changes with cartilage loss in symptomatic knee osteoarthritisD J Hunter
Boston Medical Center, Boston, Massachusetts, USA
Arthritis Rheum 54:795-801. 2006..To explore the role of meniscal tears and meniscal malposition as risk factors for subsequent cartilage loss in subjects with symptomatic osteoarthritis (OA)...
Comparison of sex steroid measurements in men by immunoassay versus mass spectroscopy and relationships with cortical and trabecular volumetric bone mineral densityS Khosla
Endocrine Research Unit, Division of Rheumatology, Department of Laboratory Medicine, and Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Osteoporos Int 19:1465-71. 2008..In men, measurement of serum testosterone and estradiol levels with immunoassays correlated with mass spectroscopic measurements, and correlations of sex steroids with volumetric bone mineral density were similar...
Relation of vertebral deformities to bone density, structure, and strengthL Joseph Melton
Division of Epidemiology, Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
J Bone Miner Res 25:1922-30. 2010..Thus significantly impaired bone density, structure, and strength compared with controls indicate that many grade 1 deformities do represent early osteoporotic fractures, with corresponding implications for clinical decision making...
Robust QCT/FEA models of proximal femur stiffness and fracture load during a sideways fall on the hipDan Dragomir-Daescu
Division of Engineering, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Ann Biomed Eng 39:742-55. 2011..The predicted stiffness (cross-validation R (2) = 0.87), fracture load (cross-validation R (2) = 0.85), and fracture patterns (83% agreement) correlated well with experimental data...
Contributions of bone density and structure to fracture risk assessment in men and womenL Joseph Melton
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Osteoporos Int 16:460-7. 2005..Because of the strong correlations, however, some judgment can be used in selecting the variables easiest to measure...
Oral bisphosphonate therapy and osteonecrosis of the jaw: what to tell the concerned patientSreenivas Koka
Metabolic Bone Disease Core Group, Division of Prosthodontics, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Int J Prosthodont 20:115-22. 2007..Within this context, management concepts and guidelines are presented to help the dental clinician allay concerns about BONJ expressed by patients receiving oral bisphosphonate therapy...
Osteoporosis in menSundeep Khosla
Endocrine Research Unit, Guggenheim 7, College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
Endocr Rev 29:441-64. 2008..Increasing awareness of osteoporosis in men among physicians and the lay public is critical for the prevention of fractures in our aging male population...
Osteoarthritis and bone mineral density: what is the relation and why does it matter?Shreyasee Amin
J Rheumatol 29:1348-9. 2002
A population-based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and menB Lawrence Riggs
Endocrine Research Unit, Division of Endocrinology and Metabolism, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
J Bone Miner Res 23:205-14. 2008..Cortical bone loss began in perimenopause in women and later in life in men. In contrast, trabecular bone loss began in young adulthood in both sexes...
Does reduced skeletal loading account for age-related bone loss?L Joseph Melton
Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
J Bone Miner Res 21:1847-55. 2006..However, in a population-based study of 375 women and 325 men (age, 21-97 years), we failed to find a close correspondence between these variables and changes in bone strength with aging...
Low levels of vitamin D and worsening of knee osteoarthritis: results of two longitudinal studiesDavid T Felson
Boston University School of Medicine, Boston, Massachusetts 02118, USA
Arthritis Rheum 56:129-36. 2007..To confirm reports that 25-hydroxyvitamin D (25[OH]D) deficiency is associated with an increased risk of joint space narrowing or cartilage loss in osteoarthritis (OA)...
Central bone marrow lesions in symptomatic knee osteoarthritis and their relationship to anterior cruciate ligament tears and cartilage lossGabriela Hernández-Molina
Boston University School of Medicine, Boston, Massachusetts 02118, USA
Arthritis Rheum 58:130-6. 2008....
Relation of serum serotonin levels to bone density and structural parameters in womenUlrike I Mödder
Endocrine Research Unit, College of Medicine, Mayo Clinic, Rochester, MN, USA
J Bone Miner Res 25:415-22. 2010..Collectively, our data provide support for a physiologic role for circulating serotonin in regulating bone mass in humans...
Structural determinants of vertebral fracture riskL Joseph Melton
Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Bone Miner Res 22:1885-92. 2007..Vertebral fractures are more strongly associated with specific bone density, structure, and strength parameters than with areal BMD, but all of these variables are correlated...
Endogenous sex hormones and cardiovascular disease incidence in menJohan Arnlov
National Heart, Lung, and Blood Institute s Framingham Heart Study, National Institutes of Health, Bethesda, Maryland, USA
Ann Intern Med 145:176-84. 2006..Yet, prospective studies relating sex hormones to CVD incidence in men have yielded inconsistent results...
Circulating osteogenic cells: characterization and relationship to rates of bone loss in postmenopausal womenAnita Undale
Endocrine Research Unit, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
Bone 47:83-92. 2010..Our study also provides "proof-of-concept" for the use of PB lin-/AP+ cells in clinical-investigative studies, and identifies several pathways that could potentially regulate rates of bone loss in postmenopausal women...
Bone structure at the distal radius during adolescent growthSalman Kirmani
College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
J Bone Miner Res 24:1033-42. 2009..Whether these deficits are more severe in children who sustain forearm fractures or persist into later life warrants further study...
Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging study of knee osteoarthritisDavid J Hunter
Boston University Clinical Epidemiology Research and Training Unit, Boston, Massachusetts, USA
Arthritis Rheum 54:1529-35. 2006..These questions were tested using longitudinal magnetic resonance imaging (MRI) data in a natural history study of symptomatic knee osteoarthritis (OA)...
Structural factors associated with malalignment in knee osteoarthritis: the Boston osteoarthritis knee studyDavid J Hunter
Clinical Epidemiology Research and Training Unit, Arthritis Center, Boston University, MA 02118, USA
J Rheumatol 32:2192-9. 2005..One of the mechanical influences on cartilage loss is limb alignment. We explored the structural factors associated with malalignment in subjects with symptomatic OA...
Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal womenL Joseph Melton
Division of Epidemology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
J Bone Miner Res 22:1442-8. 2007..Bone structure, strength and load-strength ratios contribute to forearm fracture risk independently of areal BMD...
The comparative efficacy of drug therapies used for the management of corticosteroid-induced osteoporosis: a meta-regressionShreyasee Amin
Department of Medicine, Boston Medical Center, Massachusetts, USA
J Bone Miner Res 17:1512-26. 2002..In summary, bisphosphonates are the most effective of evaluated agents for managing corticosteroid-induced osteoporosis. The efficacy of bisphosphonates is enhanced further with concomitant use of vitamin D...
