Hang Zhao

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi TLR4 is a negative regulator in noninfectious lung inflammation
    Hang Zhao
    Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    J Immunol 184:5308-14. 2010
  2. doi High MW hyaluronan inhibits smoke inhalation-induced lung injury and improves survival
    Pei Ming Huang
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Respirology 15:1131-9. 2010
  3. doi TLR4 through IFN-β promotes low molecular mass hyaluronan-induced neutrophil apoptosis
    Shaw Wei Leu
    Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, MA 02114, USA
    J Immunol 186:556-62. 2011
  4. pmc High-molecular-weight hyaluronan--a possible new treatment for sepsis-induced lung injury: a preclinical study in mechanically ventilated rats
    Yung Yang Liu
    Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, 55 Fruit Street Boston, MA 02114, USA
    Crit Care 12:R102. 2008
  5. doi Low molecular weight (LMW) heparin inhibits injury-induced femoral artery remodeling in mouse via upregulating CD44 expression
    Gaofeng Zhao
    Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Vasc Surg 53:1359-1367.e3. 2011
  6. doi Protective effect of suberoylanilide hydroxamic acid against LPS-induced septic shock in rodents
    Yongqing Li
    Department of Surgery, Division of Trauma, Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts 02114, USA
    Shock 32:517-23. 2009

Collaborators

Detail Information

Publications6

  1. doi TLR4 is a negative regulator in noninfectious lung inflammation
    Hang Zhao
    Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    J Immunol 184:5308-14. 2010
    ..These data provide a molecular level explanation for the function of TLR4 in LMW HA (200 kDa)-induced lung inflammation, as inhibition of the beta form of pro-IL-1 promotes an anti-inflammatory response...
  2. doi High MW hyaluronan inhibits smoke inhalation-induced lung injury and improves survival
    Pei Ming Huang
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Respirology 15:1131-9. 2010
    ..We hypothesized that treatment with HMW HA would block smoke inhalation lung injury by inhibiting smoke-induced lung inflammation and airway epithelial cell apoptosis...
  3. doi TLR4 through IFN-β promotes low molecular mass hyaluronan-induced neutrophil apoptosis
    Shaw Wei Leu
    Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, MA 02114, USA
    J Immunol 186:556-62. 2011
    ..Thus, TLR4 plays a novel homeostatic role in noninfectious lung inflammation by accelerating the elimination of inflammatory neutrophils...
  4. pmc High-molecular-weight hyaluronan--a possible new treatment for sepsis-induced lung injury: a preclinical study in mechanically ventilated rats
    Yung Yang Liu
    Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, 55 Fruit Street Boston, MA 02114, USA
    Crit Care 12:R102. 2008
    ..High-molecular-weight hyaluronan (HMW HA), in contrast, has been found to be anti-inflammatory. We hypothesized that HMW HA would inhibit lung injury associated with sepsis and mechanical ventilation...
  5. doi Low molecular weight (LMW) heparin inhibits injury-induced femoral artery remodeling in mouse via upregulating CD44 expression
    Gaofeng Zhao
    Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Vasc Surg 53:1359-1367.e3. 2011
    ..Studies have shown that LMW heparin could bind to CD44. We hypothesized that LMW heparin might modulate CD44 expression thereby decreasing vascular remodeling...
  6. doi Protective effect of suberoylanilide hydroxamic acid against LPS-induced septic shock in rodents
    Yongqing Li
    Department of Surgery, Division of Trauma, Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts 02114, USA
    Shock 32:517-23. 2009
    ..We report for the first time that administration of SAHA (50 mg/kg) significantly attenuates a variety of inflammatory markers and improves long-term survival after a lethal LPS insult...