Research Topics
Species | MYLES S WOLFSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
Research Grants
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Detail Information
Publications
Obesity and preeclampsia: the potential role of inflammationM Wolf
Renal Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Obstet Gynecol 98:757-62. 2001..We determined whether first-trimester elevation of serum C-reactive protein, an index of systemic inflammation, was associated with preeclampsia...
Beyond minerals and parathyroid hormone: role of active vitamin D in end-stage renal diseaseMyles Wolf
Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Semin Dial 18:302-6. 2005..Several of these nontraditional actions are reviewed with an emphasis on those that might impact hemodialysis outcomes...
Circulating levels of the antiangiogenic marker sFLT-1 are increased in first versus second pregnanciesMyles Wolf
Renal Unit, Department of Medicine, Massachusetts General Hospital and the Renal Division, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston 02114, USA
Am J Obstet Gynecol 193:16-22. 2005..Additional studies are needed to verify these findings and to further examine ethnic differences in angiogenesis factors and their potential impact on the incidence of preeclampsia...
Differential risk of hypertensive disorders of pregnancy among Hispanic womenMyles Wolf
Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Am Soc Nephrol 15:1330-8. 2004..The initial presentation of hypertension during pregnancy in Hispanic women most likely represents early preeclampsia...
Inflammation and glucose intolerance: a prospective study of gestational diabetes mellitusMyles Wolf
Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Diabetes Care 27:21-7. 2004..Although gestational diabetes mellitus (GDM) and type 2 diabetes share certain pathophysiological mechanisms, few studies have examined inflammation and risk of GDM...
First-trimester C-reactive protein and subsequent gestational diabetesMyles Wolf
Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Diabetes Care 26:819-24. 2003..We tested the hypothesis that increased inflammation, measured early in pregnancy, is associated with the subsequent development of gestational diabetes mellitus (GDM), a precursor of type 2 diabetes...
Insulin resistance but not inflammation is associated with gestational hypertensionMyles Wolf
Renal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Mass 02114, USA
Hypertension 40:886-91. 2002..Furthermore, important mechanistic differences exist in the pathogenesis of gestational hypertension comparing nulliparous and multiparous women...
Clinical research career development: the individual perspectiveMyles Wolf
Renal Unit, Department of Medicine, Massachusetts General Hospital, USA
Acad Med 77:1084-8. 2002..These important advances provide much-needed support, but additional work must be done. In the absence of further reform, academic medicine's mission to train tomorrow's clinical investigators will erode further...
First trimester insulin resistance and subsequent preeclampsia: a prospective studyMyles Wolf
Renal Unit, Departments of Medicine and Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 87:1563-8. 2002..First trimester SHBG levels may be a useful biomarker for preeclampsia, especially among lean women who otherwise would be perceived to be at low risk...
Chronic kidney disease, hypovitaminosis D, and mortality in the United StatesRajnish Mehrotra
Division of Nephrology and Hypertension, Department of Medicine, Los Angeles Biomedical Research Institute, Torrance, California 90502, USA
Kidney Int 76:977-83. 2009..Randomized, controlled trials are needed to conclusively determine whether vitamin D supplementation reduces mortality...
FGF23 or PTH: which comes first in CKD ?Tamara Isakova
Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA
Kidney Int 78:947-9. 2010..However, almost 6000 papers later, fundamental pathophysiological concepts remain unclear, particularly regarding the early pathogenesis of disordered mineral metabolism...
Research Grants
- Role of FGF-23 in Mineral Metabolism Across the Spectum of Chronic Kidney DiseaseMyles Wolf; Fiscal Year: 2007....
