J W Winkelman
Affiliation: Massachusetts General Hospital
- Sensory symptoms in restless legs syndrome: the enigma of painJohn W Winkelman
Brigham and Women s Hospital, Division of Sleep Medicine, 221 Longwood Ave, Boston, MA 02115, United States Electronic address
Sleep Med 14:934-42. 2013..Future studies are needed to better understand the experiential and biologic aspects of altered sensory experiences in RLS. ..
- Randomized polysomnography study of gabapentin enacarbil in subjects with restless legs syndromeJohn W Winkelman
Brigham and Women s Hospital Sleep Health Center, Brighton, Massachusetts, USA
Mov Disord 26:2065-72. 2011....
- Lack of hippocampal volume differences in primary insomnia and good sleeper controls: an MRI volumetric study at 3 TeslaJohn W Winkelman
Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
Sleep Med 11:576-82. 2010..Loss of HV in PI might be due to chronic hyperarousal and/or chronic sleep debt. The aim of this study was to replicate the earlier pilot report while employing a larger sample, more rigorous screening criteria, and objective sleep data...
- Polysomnographic and health-related quality of life correlates of restless legs syndrome in the Sleep Heart Health StudyJohn W Winkelman
Harvard Medical School, Boston, MA, USA
Sleep 32:772-8. 2009..The objective of this study was to analyze sleep by PSG in a population-based sample with symptoms of RLS...
- Reduced brain GABA in primary insomnia: preliminary data from 4T proton magnetic resonance spectroscopy (1H-MRS)John W Winkelman
Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, 1505 Commonwealth Avenue, Brighton, MA 02135, USA
Sleep 31:1499-506. 2008..Proton magnetic resonance spectroscopy (1H-MRS) can non-invasively determine GABA levels in human brain. Our objective was to assess GABA levels in unmedicated individuals with PI, using 1H-MRS...
- Efficacy and safety of pramipexole in restless legs syndromeJ W Winkelman
Division of Sleep Medicine, Brigham and Women s Hospital Sleep Health Center, 1505 Commonwealth Avenue, Brighton, MA 02135, USA
Neurology 67:1034-9. 2006..Pramipexole was well tolerated: The most frequent adverse events with higher occurrence in the pramipexole group were nausea (19.0% vs 4.7%) and somnolence (10.1% vs 4.7%)..
- Clinical and polysomnographic features of sleep-related eating disorderJ W Winkelman
Sleep Disorders Center, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
J Clin Psychiatry 59:14-9. 1998..However, no current nosology accurately characterizes these patients. Physicians should be aware of the existence of the disorder and the value of referring patients with sleep-related eating disorder to a sleep disorders center...
- Schizophrenia, obesity, and obstructive sleep apneaJ W Winkelman
Sleep Disorders Program, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02459, USA
J Clin Psychiatry 62:8-11. 2001..This study evaluated the risk factors for obstructive sleep apnea in psychiatric patients...
- The evoked heart rate response to periodic leg movements of sleepJ W Winkelman
Sleep Disorders Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
Sleep 22:575-80. 1999..It appears premature to conclude that periodic leg movements of sleep not associated with visible EEG arousal are clinically insignificant...
- Myoglobin, creatine kinase MB, and cardiac troponin-I to assess reperfusion after thrombolysis for acute myocardial infarction: results from TIMI 10AM J Tanasijevic
Clinical Laboratories, Brigham and Women s Hospital, Boston, MA 02115, USA
Am Heart J 134:622-30. 1997..The availability of a reliable, noninvasive serum marker of reperfusion may permit early identification of patients with occlusion after thrombolysis who might benefit from further interventions...
- Considering the causes of RLSJ W Winkelman
Departments of Medicine and Psychiatry, Harvard Medical School, Boston, MA, USA
Eur J Neurol 13:8-14. 2006..How these three identified aetiological factors, namely dopaminergic dysfunction, impaired iron homeostasis and genetic disposition, are inter-related in the genesis of RLS remains unclear...