Research Topics
| Jeremy E WiluszSummaryAffiliation: Massachusetts Institute of Technology Country: USA Publications
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Detail Information
Publications
A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tailsJeremy E Wilusz
Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Genes Dev 26:2392-407. 2012..These results provide new insights into how transcripts that lack poly(A) tails are stabilized and regulated and suggest that RNA triple-helical structures likely have key regulatory functions in vivo...
tRNAs marked with CCACCA are targeted for degradationJeremy E Wilusz
Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Science 334:817-21. 2011..We conjecture that CCACCA addition is a universal mechanism for controlling tRNA levels and preventing errors in translation...
