Jeremy E Wilusz
Affiliation: Massachusetts Institute of Technology
- A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tailsJeremy E Wilusz
Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Genes Dev 26:2392-407. 2012..These results provide new insights into how transcripts that lack poly(A) tails are stabilized and regulated and suggest that RNA triple-helical structures likely have key regulatory functions in vivo...
- tRNAs marked with CCACCA are targeted for degradationJeremy E Wilusz
Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Science 334:817-21. 2011..We conjecture that CCACCA addition is a universal mechanism for controlling tRNA levels and preventing errors in translation...