Timothy Wilens

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Impact of substance use disorder on ADHD and its treatment
    Timothy E Wilens
    Department of Pediatric Psychopharmacology, Massachusetts General Hospital, USA
    J Clin Psychiatry 68:e20. 2007
  2. pmc Effect of prior stimulant treatment for attention-deficit/hyperactivity disorder on subsequent risk for cigarette smoking and alcohol and drug use disorders in adolescents
    Timothy E Wilens
    Pediatric Psychopharmacology Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Arch Pediatr Adolesc Med 162:916-21. 2008
  3. ncbi request reprint Substance use among ADHD adults: implications of late onset and subthreshold diagnoses
    Stephen V Faraone
    Department of Psychiatry, SUNY Upstate Medical University, Syracuse, New York 13210, USA
    Am J Addict 16:24-32; quiz 33-4. 2007
  4. ncbi request reprint Do individuals with ADHD self-medicate with cigarettes and substances of abuse? Results from a controlled family study of ADHD
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Am J Addict 16:14-21; quiz 22-3. 2007
  5. ncbi request reprint Stimulants and sudden death: what is a physician to do?
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Pediatrics 118:1215-9. 2006
  6. pmc Difficulties in emotional regulation and substance use disorders: a controlled family study of bipolar adolescents
    Timothy E Wilens
    Massachusetts General Hospital, Pediatric Psychopharmacology Unit, Boston, MA 02114, USA
    Drug Alcohol Depend 132:114-21. 2013
  7. pmc Correlates of alcohol use in adults with ADHD and comorbid alcohol use disorders: exploratory analysis of a placebo-controlled trial of atomoxetine
    Timothy E Wilens
    Massachusetts General Hospital, Boston, MA 02114, USA
    Curr Med Res Opin 27:2309-20. 2011
  8. pmc Family-based association study of the BDNF, COMT and serotonin transporter genes and DSM-IV bipolar-I disorder in children
    Eric Mick
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    BMC Psychiatry 9:2. 2009
  9. ncbi request reprint Long-term atomoxetine treatment in adolescents with attention-deficit/hyperactivity disorder
    Timothy E Wilens
    Massachusetts General Hospital, Department of Psychiatry, Boston, Massachusetts, USA
    J Pediatr 149:112-9. 2006
  10. ncbi request reprint An open-label study of the tolerability of mixed amphetamine salts in adults with attention-deficit/hyperactivity disorder and treated primary essential hypertension
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA
    J Clin Psychiatry 67:696-702. 2006

Research Grants

  1. Substance Abuse in ADHD Girls
    Timothy Wilens; Fiscal Year: 2006
  2. Atomoxetine in Adolescents with ADHD and SUD
    Timothy Wilens; Fiscal Year: 2007
  3. Juvenile Bipolar Disorder and Substance Abuse
    Timothy Wilens; Fiscal Year: 2007
  4. Juvenile Bipolar Disorder and Substance Abuse
    Timothy Wilens; Fiscal Year: 2009
  5. LONG TERM DRUG ABUSE IN ADHD
    Timothy Wilens; Fiscal Year: 2002
  6. Juvenile Bipolar Disorder and Substance Abuse
    Timothy E Wilens; Fiscal Year: 2010

Detail Information

Publications106 found, 100 shown here

  1. ncbi request reprint Impact of substance use disorder on ADHD and its treatment
    Timothy E Wilens
    Department of Pediatric Psychopharmacology, Massachusetts General Hospital, USA
    J Clin Psychiatry 68:e20. 2007
    ..SUD also complicates the diagnosis of adult ADHD. Fortunately, pharmacologic treatment of ADHD does not appear to increase the risk for development of SUD in ADHD patients...
  2. pmc Effect of prior stimulant treatment for attention-deficit/hyperactivity disorder on subsequent risk for cigarette smoking and alcohol and drug use disorders in adolescents
    Timothy E Wilens
    Pediatric Psychopharmacology Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Arch Pediatr Adolesc Med 162:916-21. 2008
    ..To examine the effects of early stimulant treatment on subsequent risk for cigarette smoking and substance use disorders (SUDs) in adolescents with attention-deficit/hyperactivity disorder (ADHD)...
  3. ncbi request reprint Substance use among ADHD adults: implications of late onset and subthreshold diagnoses
    Stephen V Faraone
    Department of Psychiatry, SUNY Upstate Medical University, Syracuse, New York 13210, USA
    Am J Addict 16:24-32; quiz 33-4. 2007
    ..In contrast, subthreshold ADHD seems to be a milder form of the disorder, or perhaps a heterogeneous group of true ADHD cases and false positives...
  4. ncbi request reprint Do individuals with ADHD self-medicate with cigarettes and substances of abuse? Results from a controlled family study of ADHD
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Am J Addict 16:14-21; quiz 22-3. 2007
    ..More than one-third of adolescents and young adults endorsed using cigarettes and substances for self medication. Studies clarifying the role of self-medication in substance use disorders are necessary...
  5. ncbi request reprint Stimulants and sudden death: what is a physician to do?
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Pediatrics 118:1215-9. 2006
    ..Recently, a US Food and Drug Administration advisory committee raised concerns about cardiovascular risks and sudden death in children and adolescents with attention-deficit/hyperactivity disorder who are receiving stimulants...
  6. pmc Difficulties in emotional regulation and substance use disorders: a controlled family study of bipolar adolescents
    Timothy E Wilens
    Massachusetts General Hospital, Pediatric Psychopharmacology Unit, Boston, MA 02114, USA
    Drug Alcohol Depend 132:114-21. 2013
    ..To this end, we examined to what extent DESR was associated with SUD in a high-risk sample of adolescents with and without BD...
  7. pmc Correlates of alcohol use in adults with ADHD and comorbid alcohol use disorders: exploratory analysis of a placebo-controlled trial of atomoxetine
    Timothy E Wilens
    Massachusetts General Hospital, Boston, MA 02114, USA
    Curr Med Res Opin 27:2309-20. 2011
    ..Attention-deficit/hyperactivity disorder (ADHD) and substance use disorder are often comorbid in adults. The effects of ADHD treatment on comorbid alcohol use disorder have not been extensively studied...
  8. pmc Family-based association study of the BDNF, COMT and serotonin transporter genes and DSM-IV bipolar-I disorder in children
    Eric Mick
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    BMC Psychiatry 9:2. 2009
    ..In this report we test for association with genes coding brain-derived neurotrophic factor (BDNF), the serotonin transporter (SLC6A4), and catechol-O-methyltransferase (COMT)...
  9. ncbi request reprint Long-term atomoxetine treatment in adolescents with attention-deficit/hyperactivity disorder
    Timothy E Wilens
    Massachusetts General Hospital, Department of Psychiatry, Boston, Massachusetts, USA
    J Pediatr 149:112-9. 2006
    ..To determine the efficacy and safety of atomoxetine in adolescent subjects treated for attention-deficit/hyperactivity disorder (ADHD) for up to 2 years...
  10. ncbi request reprint An open-label study of the tolerability of mixed amphetamine salts in adults with attention-deficit/hyperactivity disorder and treated primary essential hypertension
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA
    J Clin Psychiatry 67:696-702. 2006
    ....
  11. pmc Does conduct disorder mediate the development of substance use disorders in adolescents with bipolar disorder? A case-control family study
    Timothy E Wilens
    Massachusetts General Hospital, Pediatric Psychopharmacology Unit, Boston, MA 02114, USA
    J Clin Psychiatry 70:259-65. 2009
    ..However, because bipolar disorder and CD are frequently comorbid in the young, the impact of CD in mediating SUD in bipolar disorder youth remains unclear...
  12. pmc An open study of adjunct OROS-methylphenidate in children and adolescents who are atomoxetine partial responders: I. Effectiveness
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    J Child Adolesc Psychopharmacol 19:485-92. 2009
    ..This study evaluated the effectiveness of adding OROS methylphenidate (MPH) to children who are partial responders to atomoxetine (ATMX) in the treatment of attention-deficit/hyperactivity disorder (ADHD)...
  13. ncbi request reprint Characteristics of adolescents and young adults with ADHD who divert or misuse their prescribed medications
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    J Am Acad Child Adolesc Psychiatry 45:408-14. 2006
    ..As part of a 10-year longitudinal study of youths with ADHD, the authors evaluated medication diversion or misuse at the last follow-up period...
  14. ncbi request reprint ABT-089, a neuronal nicotinic receptor partial agonist, for the treatment of attention-deficit/hyperactivity disorder in adults: results of a pilot study
    Timothy E Wilens
    Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Biol Psychiatry 59:1065-70. 2006
    ..This pilot study was designed to evaluate ABT-089, a neuronal nicotinic receptor partial agonist, as treatment for adult attention-deficit/hyperactivity disorder (ADHD)...
  15. doi request reprint Varying the wear time of the methylphenidate transdermal system in children with attention-deficit/hyperactivity disorder
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Am Acad Child Adolesc Psychiatry 47:700-8. 2008
    ..The objectives of this study were to determine the efficacy, duration of action, and safety of methylphenidate transdermal system worn for variable times by children (ages 6-12) diagnosed with ADHD...
  16. ncbi request reprint Do children and adolescents with ADHD respond differently to atomoxetine?
    Timothy E Wilens
    Massachusetts General Hospital, Boston, MA 02114 3117, USA
    J Am Acad Child Adolesc Psychiatry 45:149-57. 2006
    ..Here the authors report data contrasting the efficacy and tolerability of atomoxetine between children and adolescents with attention-deficit/hyperactivity disorder (ADHD)...
  17. ncbi request reprint Multisite controlled study of OROS methylphenidate in the treatment of adolescents with attention-deficit/hyperactivity disorder
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, YAW 6 6A, 32 Fruit Street, Boston, MA 02114, USA
    Arch Pediatr Adolesc Med 160:82-90. 2006
    ..Despite the persistence of attention-deficit/hyperactivity disorder (ADHD) into adolescence, little is known about the efficacy and tolerability of stimulant medications in this age group...
  18. ncbi request reprint An open trial of adjunctive donepezil in attention-deficit/hyperactivity disorder
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, YAW 6A, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Child Adolesc Psychopharmacol 15:947-55. 2005
    ..We sought to determine if donepezil, used adjunctively to stimulant medication, would improve residual symptoms of ADHD and EF deficits...
  19. pmc Presenting ADHD symptoms, subtypes, and comorbid disorders in clinically referred adults with ADHD
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, YAW 6A, 55 Fruit Street, Boston, MA 02114, USA
    J Clin Psychiatry 70:1557-62. 2009
    ..Comorbidity among adults with ADHD is also of great interest due to the high rates of psychiatric comorbidity, which can lead to a more persistent ADHD among adults...
  20. ncbi request reprint The clinical dilemma of using medications in substance-abusing adolescents and adults with attention-deficit/hyperactivity disorder: what does the literature tell us?
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Pediatric Psychopharmacology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    J Child Adolesc Psychopharmacol 15:787-98. 2005
    ..The role of pharmacological treatment for ADHD in these comorbid individuals remains unclear...
  21. doi request reprint A controlled trial of the methylphenidate transdermal system on before-school functioning in children with attention-deficit/hyperactivity disorder
    Timothy E Wilens
    Massachusetts General Hospital, 55 Fruit St, YAW 6900, Boston, MA 02114, USA
    J Clin Psychiatry 71:548-56. 2010
    ..Our aim was to examine the effects of the methylphenidate transdermal system (MTS) on before-school ADHD symptoms and functioning in children with ADHD...
  22. ncbi request reprint Mechanism of action of agents used in attention-deficit/hyperactivity disorder
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 67:32-8. 2006
    ..Elucidating the various mechanisms of action of ADHD medications may lead to better choices in matching potential response to the characteristics (e.g., genotype) of individuals...
  23. doi request reprint Atomoxetine treatment of adults with ADHD and comorbid alcohol use disorders
    Timothy E Wilens
    Massachusetts General Hospital, 55 Fruit Street, YAW 6900, Boston, MA 02114, USA
    Drug Alcohol Depend 96:145-54. 2008
    ..The study aim was to determine if atomoxetine was superior to placebo in improving ADHD and alcohol use in recently abstinent adults with ADHD and comorbid alcohol use disorder...
  24. pmc Further evidence of an association between adolescent bipolar disorder with smoking and substance use disorders: a controlled study
    Timothy E Wilens
    Massachusetts General Hospital, Pediatric Psychopharmacology Unit, Boston, MA 02114, USA
    Drug Alcohol Depend 95:188-98. 2008
    ..Clinicians should carefully screen adolescents with bipolar disorder for substance and cigarette use...
  25. ncbi request reprint The nature of the relationship between attention-deficit/hyperactivity disorder and substance use
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Department of Psychiatry, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 68:4-8. 2007
    ..Individuals with SUD and ADHD have a more severe and complicated course of SUD. Pharmacotherapeutic treatment of ADHD in children reduces the risk for later cigarette smoking and SUD in adulthood...
  26. doi request reprint Misuse and diversion of stimulants prescribed for ADHD: a systematic review of the literature
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Am Acad Child Adolesc Psychiatry 47:21-31. 2008
    ..The purpose of this systematic review of the literature is to evaluate the extent and characteristics of stimulant misuse and diversion in attention-deficit/hyperactivity disorder (ADHD) and non-ADHD individuals...
  27. pmc A randomized controlled trial of a novel mixed monoamine reuptake inhibitor in adults with ADHD
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Behav Brain Funct 4:24. 2008
    ..abstract:..
  28. ncbi request reprint When ADHD and substance use disorders intersect: relationship and treatment implications
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Curr Psychiatry Rep 9:408-14. 2007
    ..In contrast, medication treatment alone of adults with ADHD and current SUD is inadequate for both ADHD and SUD. Stimulant diversion continues to be of concern, particularly in older adolescents and young adults...
  29. pmc Neuronal nicotinic receptor agonists for the treatment of attention-deficit/hyperactivity disorder: focus on cognition
    Timothy E Wilens
    Massachusetts General Hospital, Pediatric Psychopharmacology Research Unit, Yawkey Center for Outpatient Care Yaw 6A, Boston, MA 02114, USA
    Biochem Pharmacol 74:1212-23. 2007
    ..Further understanding of the effects of novel neuronal nAChR agonists on specific aspects of cognitive functioning in ADHD is required to assess the full potential of this approach...
  30. ncbi request reprint Association of bipolar and substance use disorders in parents of adolescents with bipolar disorder
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, and Department of Psychiatry, Harvard Medical School, Boston, Massachusetts 02114, USA
    Biol Psychiatry 62:129-34. 2007
    ..We have previously shown that juvenile bipolar disorder (BPD) is a risk for substance use disorders (SUD). Here we examine the expression of both disorders in families of youth with BPD to evaluate the familial risk mechanism...
  31. doi request reprint Effects of methylphenidate on the catecholaminergic system in attention-deficit/hyperactivity disorder
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychopharmacol 28:S46-53. 2008
    ..Overall, the changes in catecholaminergic tone clinically manifest as improvements in attention deficit, distractibility, and motor hyperactivity in patients with ADHD...
  32. ncbi request reprint Attention deficit hyperactivity disorder and substance use disorders
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Psychiatry 163:2059-63. 2006
  33. pmc Concordance between cigarette smoking and the modified Fagerström Tolerance Questionnaire in controlled studies of ADHD
    Timothy E Wilens
    Pediatric Psychopharmacology Program, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Am J Addict 17:491-6. 2008
    ..68). Clinicians and researchers using the mFTQ in adolescents and young adults should consider a cutoff score of 3 to be indicative of cigarette smoking...
  34. pmc Understanding attention-deficit/hyperactivity disorder from childhood to adulthood
    Timothy E Wilens
    Timothy E Wilens, MD, Pediatric Psychopharmacology Unit, YAW 6A, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    Postgrad Med 122:97-109. 2010
    ..Pharmacotherapy, including stimulants, noradrenergic agents, α-agonists, and antidepressants, plays a fundamental role in the long-term management of ADHD...
  35. pmc The intersection of attention-deficit/hyperactivity disorder and substance abuse
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, and Center for Addiction Medicine, Massachusetts General Hospital, Department of Psychiatry, Harvard Medical School, Boston, MA 02114, USA
    Curr Opin Psychiatry 24:280-5. 2011
    ..In this report more recent work exploring the developmental relationship between ADHD and SUDs and associated concurrent disorders is discussed...
  36. pmc An update on the pharmacotherapy of attention-deficit/hyperactivity disorder in adults
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Child Psychiatry Service, Massachusetts General Hospital, Boston, MA, USA
    Expert Rev Neurother 11:1443-65. 2011
    ..The aggregate literature shows that the stimulants and catecholaminergic nonstimulants investigated had a clinically significant beneficial effect on treating ADHD in adults...
  37. ncbi request reprint A clinical perspective of attention-deficit/hyperactivity disorder into adulthood
    Timothy E Wilens
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    J Clin Psychiatry 65:1301-13. 2004
    ..Attention-deficit/hyperactivity disorder (ADHD) is a common psychiatric disorder that affects all age groups. Recent data on the clinical presentation, comorbidity, neurobiology, and treatment are reviewed...
  38. ncbi request reprint Blood pressure changes associated with medication treatment of adults with attention-deficit/hyperactivity disorder
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, MA 02114, USA
    J Clin Psychiatry 66:253-9. 2005
    ..To evaluate the effects of medications used in the treatment of adults with attention-deficit/hyperactivity disorder (ADHD) on blood pressure and pulse...
  39. pmc Does ADHD predict substance-use disorders? A 10-year follow-up study of young adults with ADHD
    Timothy E Wilens
    Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston MA 02114, USA
    J Am Acad Child Adolesc Psychiatry 50:543-53. 2011
    ..The main aims of this study were to identify clinically meaningful characteristics of children that predicted the future development of SUDs and to see whether the role of these characteristics varied by sex...
  40. ncbi request reprint Bupropion XL in adults with attention-deficit/hyperactivity disorder: a randomized, placebo-controlled study
    Timothy E Wilens
    Pediatric Psychopharmacology Research, Yawkey Center for Outpatient Care, Massachusetts General Hospital, Boston, Massachusetts 021143 3117, USA
    Biol Psychiatry 57:793-801. 2005
    ..This study evaluated the efficacy and safety of an extended-release, once-daily formulation of bupropion (XL) in the treatment of adults with ADHD...
  41. ncbi request reprint Attention-deficit/hyperactivity disorder and the substance use disorders: the nature of the relationship, subtypes at risk, and treatment issues
    Timothy E Wilens
    Substance Abuse Services, Pediatric Psychopharmacology Clinic, Massachusetts General Hospital, Boston 02114, USA
    Psychiatr Clin North Am 27:283-301. 2004
    ..Given the prevalence and major morbidity and impairment caused by SUD and ADHD. prevention and treatment strategies for these patients need to be developed and evaluated further...
  42. ncbi request reprint Impact of ADHD and its treatment on substance abuse in adults
    Timothy E Wilens
    Department of Psychiatry, Harvard Medical School, Substance Abuse Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston 02114 3117, USA
    J Clin Psychiatry 65:38-45. 2004
    ..Careful monitoring of patients during treatment is necessary to ensure compliance with the treatment plan...
  43. ncbi request reprint Patterns of comorbidity and dysfunction in clinically referred preschool and school-age children with bipolar disorder
    Timothy E Wilens
    Johnson and Johnson Center for the Study of Pediatric Psychopathology, Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Child Adolesc Psychopharmacol 13:495-505. 2003
    ..This study reports on the clinical characteristics, psychiatric comorbidity, and functioning of preschoolers identified with BPD who were referred to a pediatric psychiatric clinic...
  44. ncbi request reprint Attention-deficit/hyperactivity disorder in adults
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114 3139, USA
    JAMA 292:619-23. 2004
  45. ncbi request reprint Characteristics of adults with attention deficit hyperactivity disorder plus substance use disorder: the role of psychiatric comorbidity
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, MA, USA
    Am J Addict 14:319-27. 2005
    ..Clinicians need to be attentive to other psychiatric disorders that may occur in the large group of adults with ADHD + SUD...
  46. pmc Safety and efficacy of ABT-089 in pediatric attention-deficit/hyperactivity disorder: results from two randomized placebo-controlled clinical trials
    Timothy E Wilens
    Massachusetts General Hospital, Pediatric Psychopharmacology Unit, 55 Fruit Street, Boston, MA 02114, USA
    J Am Acad Child Adolesc Psychiatry 50:73-84.e1. 2011
    ..To assess the safety and efficacy of ABT-089, a novel α(4)β(2) neuronal nicotinic receptor partial agonist, vs. placebo in children with attention-deficit/hyperactivity disorder (ADHD)...
  47. ncbi request reprint ADHD treatment with once-daily OROS methylphenidate: final results from a long-term open-label study
    Timothy Wilens
    Massachusetts General Hospital, Pediatric Psychopharmacology, Boston, MA 02114, USA
    J Am Acad Child Adolesc Psychiatry 44:1015-23. 2005
    ..This article presents final results from an open-label, multisite study of a once-daily formulation of methylphenidate (MPH), OROS MPH...
  48. ncbi request reprint Influence of parental SUD and ADHD on ADHD in their offspring: preliminary results from a pilot-controlled family study
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Addict 14:179-87. 2005
    ..Replication studies clarifying the nature and strength of the association are necessary...
  49. ncbi request reprint Alcohol, drugs, and attention-deficit/ hyperactivity disorder: a model for the study of addictions in youth
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    J Psychopharmacol 20:580-8. 2006
    ..ADHD is an important antecedent disorder in children and adolescents worthy of further targeted preventive efforts to diminish the risk for cigarette smoking and SUD...
  50. pmc Do executive function deficits predict later substance use disorders among adolescents and young adults?
    Timothy E Wilens
    Clinical and Research Program in Pediatric Psychopharmacology, PediatricPsychopharmacology Unit, Massachusetts General Hospital, 55 Parkman Street, Boston, MA 02114, USA
    J Am Acad Child Adolesc Psychiatry 50:141-9. 2011
    ..Therefore, we examined whether earlier EFD was a risk factor for subsequent cigarette smoking and SUD and further explored the relationship between EFD and SUD...
  51. doi request reprint A controlled trial of extended-release guanfacine and psychostimulants for attention-deficit/hyperactivity disorder
    Timothy E Wilens
    Massachusetts General Hospital, Boston, MA, USA
    J Am Acad Child Adolesc Psychiatry 51:74-85.e2. 2012
    ....
  52. ncbi request reprint Risk of substance use disorders in adolescents with bipolar disorder
    Timothy E Wilens
    Pediatric Psychopharmacology Unit, Child Psychiatric Service, Massachusetts General Hospital, and Harvard Medical School, Boston, MA 02114, USA
    J Am Acad Child Adolesc Psychiatry 43:1380-6. 2004
    ..Considering the public health importance of this issue, the authors now report on a controlled study of adolescents with and without BPD to evaluate the risk of SUD...
  53. ncbi request reprint Evidence-based pharmacotherapy for attention-deficit hyperactivity disorder
    Joseph Biederman
    Massachusetts General Hospital, ACC 725, Boston, MA 02114, USA
    Int J Neuropsychopharmacol 7:77-97. 2004
    ..Further, more research is needed on the efficacy of treatment for comorbid ADHD, use of combined medications, and the combination of medication and psychosocial treatment...
  54. doi request reprint Cardiovascular effects of longer-term, high-dose OROS methylphenidate in adolescents with attention deficit hyperactivity disorder
    Paul Hammerness
    Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02138, USA
    J Pediatr 155:84-9, 89.e1. 2009
    ..To examine the effects of high doses of extended-release methylphenidate (OROS MPH) on cardiovascular variables in adolescents with attention deficit hyperactivity disorder (ADHD)...
  55. pmc Comorbidity in pediatric bipolar disorder
    Gagan Joshi
    Pervasive Developmental Disorders Program, Clinical and Research Programs in Pediatric Psychopharmacology, Massachusetts General Hospital, Harvard Medical School, 32 Fruit Street, Boston, MA 02114, USA
    Child Adolesc Psychiatr Clin N Am 18:291-319, vii-viii. 2009
    ..Future longitudinal studies to address the relationship and the impact of comorbid disorders on course and therapeutic response over time are required in youth with BPD...
  56. ncbi request reprint A large, double-blind, randomized clinical trial of methylphenidate in the treatment of adults with attention-deficit/hyperactivity disorder
    Thomas Spencer
    Pediatric Psychopharmacology Unit, Psychiatry Service Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Biol Psychiatry 57:456-63. 2005
    ..A previous, pilot study by our group suggested that these results were due to inadequate dosing...
  57. doi request reprint Family based association study of pediatric bipolar disorder and the dopamine transporter gene (SLC6A3)
    Eric Mick
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Med Genet B Neuropsychiatr Genet 147:1182-5. 2008
    ..These data provide suggestive evidence supporting a role for SLC6A3 in the etiology of pediatric bipolar disorder...
  58. pmc An open study of adjunct OROS-methylphenidate in children who are atomoxetine partial responders: II. Tolerability and pharmacokinetics
    Paul Hammerness
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Harvard Medical School, Boston Massachusetts, USA
    J Child Adolesc Psychopharmacol 19:493-9. 2009
    ..The aim of this study was to evaluate the tolerability of adding OROS methylphenidate (MPH) to children who are partial responders to atomoxetine (ATMX) in the treatment of attention-deficit/hyperactivity disorder (ADHD)...
  59. ncbi request reprint Stimulant treatment of adult attention-deficit/hyperactivity disorder
    Thomas Spencer
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychiatr Clin North Am 27:361-72. 2004
    ..As in childhood ADHD, medication remains a key component of treatment for adults with ADHD. More studies are needed to evaluate the efficacy and safety of stimulants over the long-term and their impact on quality of life...
  60. ncbi request reprint Donepezil in the treatment of ADHD-like symptoms in youths with pervasive developmental disorder: a case series
    Robert L Doyle
    Department of Psychiatry, Harvard Medical School, USA
    J Atten Disord 9:543-9. 2006
    ..Because work in dementia documents improvement in executive function deficits with the acetylcholinesterase inhibitor donepezil, the authors reason that similar benefits could be obtained in PDD...
  61. ncbi request reprint Family based association analysis of statistically derived quantitative traits for drug use in ADHD and the dopamine transporter gene
    Jessica Lasky-Su
    Genetics Research Program and Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY 13210, and Pediatric psychopharmacology Unit, Massachusetts General Hospital, Boston, USA
    Addict Behav 31:1088-99. 2006
    ..To determine whether SNPs within the dopamine transporter gene (DAT) are associated with quantitative phenotypes generated from drug frequency variables in an ADHD sample...
  62. ncbi request reprint ADHD treatment with once-daily OROS methylphenidate: interim 12-month results from a long-term open-label study
    Timothy Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital and Harvard Medical School, 15 Parkman Street, Boston, MA 02114, USA
    J Am Acad Child Adolesc Psychiatry 42:424-33. 2003
    ..This article reports an interim analysis of a 24-month study evaluating the 12-month tolerability and effectiveness of a once-daily OROS formulation of methylphenidate (OROS MPH) in children with ADHD...
  63. doi request reprint Plasma methylphenidate concentrations in youths treated with high-dose osmotic release oral system formulation
    Jonathan R Stevens
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, Massachusetts 02138, USA
    J Child Adolesc Psychopharmacol 20:49-54. 2010
    ....
  64. ncbi request reprint Novel treatments for attention-deficit/hyperactivity disorder in children
    Thomas J Spencer
    Pediatric Psychopharmacology Unit, Psychiatry Service, Massachusetts General Hospital, Boston, USA
    J Clin Psychiatry 63:16-22. 2002
    ....
  65. pmc Familial transmission of derived phenotypes for molecular genetic studies of substance use disorders
    Stephen V Faraone
    Department of Psychiatry, SUNY Upstate Medical University, 750 East Adams St, Syracuse, NY 13210, USA
    Drug Alcohol Depend 92:100-7. 2008
    ..001; cognitive impairment: OR=1.33, p=0.04); in offspring, baseline psychopathology predicted SUD at follow-up assessments (OR=1.55, p=0.01). Results suggest that these candidate SUD phenotypes may be useful for genetic studies of SUD...
  66. ncbi request reprint New developments in the treatment of ADHD
    Joseph Biederman
    Dept of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    J Clin Psychiatry 67:148-59. 2006
  67. ncbi request reprint Drug therapy for adults with attention-deficit hyperactivity disorder
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Drugs 63:2395-411. 2003
    ..Further studies are necessary to evaluate the long-term effectiveness and tolerability of various agents, functional and neuropsychological outcomes, and the use of various agents in specific subgroups of adults with ADHD...
  68. ncbi request reprint Neuropsychological functioning in youth with bipolar disorder
    Alysa E Doyle
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    Biol Psychiatry 58:540-8. 2005
    ..We compared neuropsychological and academic functioning of youth with and without DSM-IV BPD, controlling for effects of comorbid ADHD...
  69. ncbi request reprint Influence of gender on attention deficit hyperactivity disorder in children referred to a psychiatric clinic
    Joseph Biederman
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Psychiatry 159:36-42. 2002
    ..In this study the authors systematically examined the impact of gender on the clinical features of ADHD in a group of children referred to a clinic...
  70. pmc Cigarette smoking associated with attention deficit hyperactivity disorder
    Timothy E Wilens
    Pediatric Psychopharmacology Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    J Pediatr 153:414-9. 2008
    ..To evaluate the association between attention deficit hyperactivity disorder (ADHD) and severity of physical dependence on nicotine in a controlled study of adolescents and young adults with ADHD...
  71. ncbi request reprint Does stimulant therapy of attention-deficit/hyperactivity disorder beget later substance abuse? A meta-analytic review of the literature
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Pediatrics 111:179-85. 2003
    ..We investigated all long-term studies in which pharmacologically treated and untreated youths with ADHD were examined for later SUD outcomes...
  72. ncbi request reprint Overview and neurobiology of attention-deficit/hyperactivity disorder
    Thomas J Spencer
    Pediatric Psychopharmacology Unit, Psychiatry Service, Massachusetts General Hospital, Boston, USA
    J Clin Psychiatry 63:3-9. 2002
    ..Therefore, the treatment characteristics of newer, more selective treatments such as atomoxetine should continue to be explored in ADHD...
  73. ncbi request reprint Effects of once-daily osmotic-release methylphenidate on blood pressure and heart rate in children with attention-deficit/hyperactivity disorder: results from a one-year follow-up study
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychopharmacol 24:36-41. 2004
    ..We evaluated the longer-term effects on vital signs of once-daily osmotic-release methylphenidate (MPH, Concerta) in children with ADHD...
  74. ncbi request reprint An open trial of bupropion for the treatment of adults with attention-deficit/hyperactivity disorder and bipolar disorder
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Biol Psychiatry 54:9-16. 2003
    ..Given the efficacy of bupropion for ADHD in adults, as well as its use in the management of bipolar depression, we studied the tolerability and efficacy of sustained-release (SR) bupropion in adults with ADHD plus BPD...
  75. ncbi request reprint A naturalistic study of the effects of pharmacotherapy on substance use disorders among ADHD adults
    Stephen V Faraone
    Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY 13210, USA
    Psychol Med 37:1743-52. 2007
    ....
  76. doi request reprint Atomoxetine treatment outcomes in adolescents and young adults with attention-deficit/hyperactivity disorder: results from a post hoc, pooled analysis
    Lenard A Adler
    Department of Psychiatry, New York University School of Medicine, New York, New York 10016, USA
    Clin Ther 34:363-73. 2012
    ..As a first step, we present the results of a post hoc, pooled analysis that compared the efficacy and safety profile of atomoxetine in these 2 patient populations...
  77. ncbi request reprint Does stimulant treatment lead to substance use disorders?
    Stephen V Faraone
    Harvard Medical School, and Massachusetts General Hospital, Boston 02114 3139, USA
    J Clin Psychiatry 64:9-13. 2003
    ..The implication of this finding is unquestionably one with enormous value both clinically and as a matter of public health...
  78. ncbi request reprint Pharmacotherapy of ADHD in adults
    Timothy E Wilens
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    CNS Spectr 13:11-3. 2008
  79. ncbi request reprint ADHD: prevalence, diagnosis, and issues of comorbidity
    Timothy E Wilens
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    CNS Spectr 12:1-5. 2007
  80. ncbi request reprint Psychiatric comorbidity and functioning in clinically referred preschool children and school-age youths with ADHD
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    J Am Acad Child Adolesc Psychiatry 41:262-8. 2002
    ..We evaluated the clinical characteristics, psychiatric comorbidity, and functioning of preschool children and school-age youths with ADHD referred to a pediatric psychiatric clinic for evaluation...
  81. ncbi request reprint Can adults with attention-deficit/hyperactivity disorder be distinguished from those with comorbid bipolar disorder? Findings from a sample of clinically referred adults
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Biol Psychiatry 54:1-8. 2003
    ..We now evaluate the clinical characteristics of referred adults with (n = 24) and without BPD (n = 27)...
  82. ncbi request reprint A family study of the high-risk children of opioid- and alcohol-dependent parents
    Timothy E Wilens
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston 02114, USA
    Am J Addict 11:41-51. 2002
    ..With a growing consensus that certain risk factors for later SUD start in childhood with potentially treatable childhood-onset disorders, new preventive approaches for individuals at risk may be developed targeting childhood precursors of..
  83. ncbi request reprint Bupropion SR for the treatment of substance-abusing outpatient adolescents with attention-deficit/hyperactivity disorder and mood disorders
    Ramon Solhkhah
    Pediatric Psychopharmacology Unit, Division of Child and Adolescent Psychiatry, Massachusetts General Hospital and Harvard Medical School, USA
    J Child Adolesc Psychopharmacol 15:777-86. 2005
    ..The ratings were completed at baseline, at month 3, and at the 6-month endpoint. Bupropion SR was initiated at 100 mg once-daily and titrated naturalistically to a maximum dose of 400 mg/day...
  84. ncbi request reprint Long-term safety and effectiveness of mixed amphetamine salts extended release in adults with ADHD
    Joseph Biederman
    Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    CNS Spectr 10:16-25. 2005
    ..Assess the long-term safety and effectiveness of mixed amphetamine salts extended release (MAS XR) in adults with attention-deficit/hyperactivity disorder (ADHD) combined subtype...
  85. pmc Family-based genome-wide association scan of attention-deficit/hyperactivity disorder
    Eric Mick
    Massachusetts General Hospital, 55 Fruit Street Warren 705, Boston, MA 02114, USA
    J Am Acad Child Adolesc Psychiatry 49:898-905.e3. 2010
    ..We have conducted a third, independent, multisite GWAS of DSM-IV-TR ADHD...
  86. ncbi request reprint Assessing cannabis use in adolescents and young adults: what do urine screen and parental report tell you?
    Martin Gignac
    Pediatric Psychopharmacology Unit of the Psychiatry Department, Massachusetts General Hospital, Boston, MA, USA
    J Child Adolesc Psychopharmacol 15:742-50. 2005
    ..Our analysis compares three approaches to detect the most common drug abused in early adulthood, cannabis: (1) report on direct structured interview; (2) indirect parental report; and (3) urine toxicology screen...
  87. doi request reprint Adult psychiatric outcomes of girls with attention deficit hyperactivity disorder: 11-year follow-up in a longitudinal case-control study
    Joseph Biederman
    Clinical and Research Programs in Pediatric Psychopharmacology, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Psychiatry 167:409-17. 2010
    ..Few follow-up studies have been conducted of girls with ADHD, and none have followed girls into adulthood. The authors sought to estimate the prevalence of psychopathology in girls with and without ADHD followed into young adulthood...
  88. ncbi request reprint Impact of executive function deficits and attention-deficit/hyperactivity disorder (ADHD) on academic outcomes in children
    Joseph Biederman
    Pediatric Psychopharmacology Unit, Psychiatry Department, Massachusetts General Hospital, Boston, MA 02114, USA
    J Consult Clin Psychol 72:757-66. 2004
    ..Children and adolescents with ADHD and EFDs were found to be at high risk for significant impairments in academic functioning. These results support screening children with ADHD for EFDs to prevent academic failure...
  89. ncbi request reprint Is cigarette smoking a gateway to alcohol and illicit drug use disorders? A study of youths with and without attention deficit hyperactivity disorder
    Joseph Biederman
    Department of Psychiatry, Harvard Medical School, USA
    Biol Psychiatry 59:258-64. 2006
    ....
  90. ncbi request reprint Does social class predict substance problems in young adults with ADHD?
    Michael C Monuteaux
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Am J Addict 16:403-9. 2007
    ..No significant association was found in controls. These findings indicate that substance use risk in ADHD subjects is especially vulnerable to social class...
  91. ncbi request reprint Young adult outcome of attention deficit hyperactivity disorder: a controlled 10-year follow-up study
    Joseph Biederman
    Pediatric Psychopharmacology Unit of the Psychiatry Department, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychol Med 36:167-79. 2006
    ..Our objective was to estimate the lifetime prevalence of psychopathology in a sample of youth with and without attention deficit hyperactivity disorder (ADHD) through young adulthood using contemporaneous diagnostic and analytic techniques...
  92. ncbi request reprint Efficacy and safety of mixed amphetamine salts extended release (Adderall XR) in the management of attention-deficit/hyperactivity disorder in adolescent patients: a 4-week, randomized, double-blind, placebo-controlled, parallel-group study
    Thomas J Spencer
    Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts 02114, USA
    Clin Ther 28:266-79. 2006
    ..The ability to recognize and diagnose attention-deficit/hyperactivity disorder (ADHD) has increased in recent years. The persistence of ADHD symptoms puts adolescents with ADHD at risk for long-term adverse psychosocial outcomes...
  93. pmc Do stimulants protect against psychiatric disorders in youth with ADHD? A 10-year follow-up study
    Joseph Biederman
    Psychiatry Department, Massachusetts General Hospital, Clinical and Research Programs in PediatricPsychopharmacology and Adult ADHD, Boston, Massachusetts 02114, USA
    Pediatrics 124:71-8. 2009
    ..We tested the association between stimulant treatment and the subsequent development of psychiatric comorbidity in a longitudinal sample of patients with ADHD...
  94. pmc Examination of concordance between maternal and youth reports in the diagnosis of pediatric bipolar disorder
    Joseph Biederman
    Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, 55 Fruit Street, Warren 705, Boston, MA 02114, USA
    Bipolar Disord 11:298-306. 2009
    ..To this end we compared discordant (mother positive and youth negative) and concordant (mother and youth positive) cases...
  95. ncbi request reprint Psychopathology in females with attention-deficit/hyperactivity disorder: a controlled, five-year prospective study
    Joseph Biederman
    Pediatric Psychopharmacology Unit of the Psychiatry Department, Massachusetts General Hospital, 32 Fruit Street, Boston, MA 02114, USA
    Biol Psychiatry 60:1098-105. 2006
    ..This study estimated the lifetime burden of comorbid psychopathology in a large sample of girls with and without ADHD followed up over five years...
  96. ncbi request reprint Treatment of ADHD with stimulant medications: response to Nissen perspective in the New England Journal of Medicine
    Joseph Biederman
    Clinical Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Am Acad Child Adolesc Psychiatry 45:1147-50. 2006
  97. doi request reprint The familial association between cigarette smoking and ADHD: a study of clinically referred girls with and without ADHD, and their families
    Michael C Monuteaux
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    Nicotine Tob Res 10:1549-58. 2008
    ..These findings support the hypothesis that the combination of ADHD and smoking comprises an etiologically distinct familial subtype of ADHD in girls...
  98. ncbi request reprint Familial risk analyses of attention deficit hyperactivity disorder and substance use disorders
    Joseph Biederman
    Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, 55 Fruit St, Warren 705, Boston, MA 02114, USA
    Am J Psychiatry 165:107-15. 2008
    ..A robust and bidirectional comorbidity between attention deficit hyperactivity disorder (ADHD) and psychoactive substance use disorder (alcohol or drug abuse or dependence) has been consistently reported in the extant literature...
  99. ncbi request reprint Cognitive-behavioral therapy for ADHD in medication-treated adults with continued symptoms
    Steven A Safren
    Massachusetts General Hospital, MGH Psychiatry, Harvard Medical School, WACC 815, 15 Parkman Street, Boston, MA 02114, USA
    Behav Res Ther 43:831-42. 2005
    ..02). These data support the hypothesis that CBT for adults with ADHD with residual symptoms is a feasible, acceptable, and potentially efficacious next-step treatment approach, worthy of further testing...
  100. ncbi request reprint Nonstimulant treatment of adult attention-deficit/hyperactivity disorder
    Thomas Spencer
    Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychiatr Clin North Am 27:373-83. 2004
    ..Such developments have the promise of improving the quality of life of the millions of affected patients and their families worldwide...
  101. ncbi request reprint Short- and long-term cardiovascular effects of mixed amphetamine salts extended release in children
    Robert L Findling
    University Hospitals of Cleveland, Cleveland, Ohio 44106 5080, USA
    J Pediatr 147:348-54. 2005
    ....

Research Grants20

  1. Substance Abuse in ADHD Girls
    Timothy Wilens; Fiscal Year: 2006
    ..Thus, the research, approach, and goals of this R01 application are consistent with those underscored in the PA and by the Institute of Medicine as being of the highest research priority. ..
  2. Atomoxetine in Adolescents with ADHD and SUD
    Timothy Wilens; Fiscal Year: 2007
    ..In this manner, the candidate will satisfy overall career development and mentoring objectives of the K24 award. ..
  3. Juvenile Bipolar Disorder and Substance Abuse
    Timothy Wilens; Fiscal Year: 2007
    ..Since BPD is identifiable and treatable, findings from the four-year follow-up will provide valuable information to formulate prevention and early intervention strategies. ..
  4. Juvenile Bipolar Disorder and Substance Abuse
    Timothy Wilens; Fiscal Year: 2009
    ..Since BPD is identifiable and treatable, findings from the four-year follow-up will provide valuable information to formulate prevention and early intervention strategies. ..
  5. LONG TERM DRUG ABUSE IN ADHD
    Timothy Wilens; Fiscal Year: 2002
    ..abstract_text> ..
  6. Juvenile Bipolar Disorder and Substance Abuse
    Timothy E Wilens; Fiscal Year: 2010
    ..Since BPD is identifiable and treatable, findings from the four-year follow-up will provide valuable information to formulate prevention and early intervention strategies. ..