A P Weiss

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi request reprint Patient- and practice-related determinants of emergency department length of stay for patients with psychiatric illness
    Anthony P Weiss
    Partners Psychiatry and Mental Health, Division of Health Services Research, Boston, MA, USA
    Ann Emerg Med 60:162-71.e5. 2012
  2. pmc Aberrant frontoparietal function during recognition memory in schizophrenia: a multimodal neuroimaging investigation
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Neurosci 29:11347-59. 2009
  3. doi request reprint Auditory stimulus repetition effects on cortical hemoglobin oxygenation: a near-infrared spectroscopy investigation
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA
    Neuroreport 19:161-5. 2008
  4. pmc Distinguishing familiarity-based from source-based memory performance in patients with schizophrenia
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    Schizophr Res 99:208-17. 2008
  5. ncbi request reprint Measuring the impact of medical research: moving from outputs to outcomes
    Anthony P Weiss
    Department of Psychiatry, MGH East, Charlestown, MA 02129, USA
    Am J Psychiatry 164:206-14. 2007
  6. ncbi request reprint Fronto-hippocampal function during temporal context monitoring in schizophrenia
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02129, USA
    Biol Psychiatry 60:1268-77. 2006
  7. ncbi request reprint Treatment of cardiac risk factors among patients with schizophrenia and diabetes
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, 02114, USA
    Psychiatr Serv 57:1145-52. 2006
  8. ncbi request reprint Neuroimaging of hallucinations: a review of the literature
    A P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston 02114, USA
    Psychiatry Res 92:61-74. 1999
  9. ncbi request reprint Anterior and posterior hippocampal volumes in schizophrenia
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    Schizophr Res 73:103-12. 2005
  10. ncbi request reprint Intact suppression of increased false recognition in schizophrenia
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston 02114, USA
    Am J Psychiatry 159:1506-13. 2002

Research Grants

Detail Information

Publications32

  1. doi request reprint Patient- and practice-related determinants of emergency department length of stay for patients with psychiatric illness
    Anthony P Weiss
    Partners Psychiatry and Mental Health, Division of Health Services Research, Boston, MA, USA
    Ann Emerg Med 60:162-71.e5. 2012
    ..To identify patient and clinical management factors related to emergency department (ED) length of stay for psychiatric patients...
  2. pmc Aberrant frontoparietal function during recognition memory in schizophrenia: a multimodal neuroimaging investigation
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Neurosci 29:11347-59. 2009
    ..Inefficient utilization of prefrontal-parietal networks, with compensatory activation in temporal regions, may thus contribute to deficient old-new item recognition in schizophrenia...
  3. doi request reprint Auditory stimulus repetition effects on cortical hemoglobin oxygenation: a near-infrared spectroscopy investigation
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA
    Neuroreport 19:161-5. 2008
    ..These findings provide preliminary support for a relationship between the perceptual characteristics of auditory stimuli and modulation of cortical oxygenation as measured via an emerging neuromonitoring technique...
  4. pmc Distinguishing familiarity-based from source-based memory performance in patients with schizophrenia
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    Schizophr Res 99:208-17. 2008
    ..Yet the exact nature of these deficits remains a matter of some debate. This study sought to examine performance on two distinct aspects of memory performance: familiarity-based and source-based memory processes...
  5. ncbi request reprint Measuring the impact of medical research: moving from outputs to outcomes
    Anthony P Weiss
    Department of Psychiatry, MGH East, Charlestown, MA 02129, USA
    Am J Psychiatry 164:206-14. 2007
    ....
  6. ncbi request reprint Fronto-hippocampal function during temporal context monitoring in schizophrenia
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02129, USA
    Biol Psychiatry 60:1268-77. 2006
    ..Given the importance of the hippocampus and prefrontal cortex (PFC) in this type of memory, we hypothesized that this cognitive deficit stemmed from aberrant fronto-hippocampal activation during memory retrieval...
  7. ncbi request reprint Treatment of cardiac risk factors among patients with schizophrenia and diabetes
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, 02114, USA
    Psychiatr Serv 57:1145-52. 2006
    ..The appropriateness and effectiveness of the outpatient medical management of cardiac risk factors for patients with diabetes who had a diagnosis of schizophrenia or a related psychotic syndrome were examined...
  8. ncbi request reprint Neuroimaging of hallucinations: a review of the literature
    A P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston 02114, USA
    Psychiatry Res 92:61-74. 1999
    ..Furthermore, neural activation may be specifically related to distinct phenomenological features of the hallucinatory experience. Further work is needed to better understand the neural basis of hallucinations...
  9. ncbi request reprint Anterior and posterior hippocampal volumes in schizophrenia
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    Schizophr Res 73:103-12. 2005
    ..Here we present volume estimates of anterior and posterior hippocampal volumes using a novel morphometric protocol...
  10. ncbi request reprint Intact suppression of increased false recognition in schizophrenia
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston 02114, USA
    Am J Psychiatry 159:1506-13. 2002
    ..By studying pictures of the target word during encoding, healthy adults can suppress false recognition. This study examined the effect of pictorial encoding on subsequent recognition of repeated foils in patients with schizophrenia...
  11. ncbi request reprint Late-onset obsessive-compulsive disorder: a case series
    A P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston 02114, USA
    J Neuropsychiatry Clin Neurosci 12:265-8. 2000
    ..Four of the 5 patients had intracerebral lesions in the frontal lobes and caudate nuclei, findings consistent with current theories about the pathogenesis of "idiopathic" OCD...
  12. ncbi request reprint Neuroimaging of declarative memory in schizophrenia
    A P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston 02114, USA
    Scand J Psychol 42:239-50. 2001
    ..Memory impairment in schizophrenia appears to involve abnormal connectivity between the prefrontal cortex and three regions important in normal learning and memory: the hippocampus, thalamus, and cerebellum...
  13. ncbi request reprint Impaired hippocampal function during the detection of novel words in schizophrenia
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
    Biol Psychiatry 55:668-75. 2004
    ..This study examined this relationship by measuring the volume of the hippocampus and its activation during memory task performance...
  14. ncbi request reprint Hippocampal activation during transitive inference in humans
    Stephan Heckers
    Department of Psychiatry, Massachusetts General Hospital, East CNY 9112, Bldg 149, Thirteenth Street, Charlestown, MA 02129, USA
    Hippocampus 14:153-62. 2004
    ..We conclude that immediate access to simple stimulus-stimulus relationships is mediated via the parahippocampal gyrus, whereas the flexible representation of memory requires the recruitment of the hippocampus...
  15. ncbi request reprint Reversed hemispheric asymmetry during simple visual perception in schizophrenia
    Stephan Heckers
    Department of Psychiatry, Massachusetts General Hospital East, Harvard Medical School, Charlestown, MA 02129, USA
    Psychiatry Res 116:25-32. 2002
    ..These results are consistent with the notion of reversed hemispheric asymmetry during the processing of sensory information in schizophrenia...
  16. doi request reprint Effects of transdermal nicotine on episodic memory in non-smokers with and without schizophrenia
    Lindsay E Jubelt
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    Psychopharmacology (Berl) 199:89-98. 2008
    ..Nicotinic agonists may improve attention and memory in humans and may ameliorate some cognitive deficits associated with neuropsychiatric disorders such as schizophrenia...
  17. ncbi request reprint Anterior cingulate cortex activation during cognitive interference in schizophrenia
    Stephan Heckers
    Department of Psychiatry, Massachusetts General Hospital, Boston, 02129, USA
    Am J Psychiatry 161:707-15. 2004
    ..Previous studies have reported evidence of structural and functional abnormalities in the anterior cingulate cortex of patients with schizophrenia...
  18. ncbi request reprint The effects of transdermal nicotine on cognition in nonsmokers with schizophrenia and nonpsychiatric controls
    Ruth S Barr
    The Schizophrenia Program of the Massachusetts General Hospital, Boston, MA 02114, USA
    Neuropsychopharmacology 33:480-90. 2008
    ..These results confirm previous findings that a single dose of nicotine improves attention and suggest that nicotine may specifically improve response inhibition in nonsmokers with schizophrenia...
  19. doi request reprint Interactive effects of COMT Val108/158Met and MTHFR C677T on executive function in schizophrenia
    Joshua L Roffman
    Schizophrenia Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Am J Med Genet B Neuropsychiatr Genet 147:990-5. 2008
    ..It is plausible that cumulative effects of the MTHFR T and COMT Val alleles on intracellular methylation profiles and prefrontal dopamine transmission underlie their interactive effect on perseverative errors...
  20. ncbi request reprint Reach of benchmark psychiatric trial results to community-based providers: a case study of CATIE
    Timothy J Petersen
    Massachusetts General Hospital Department of Psychiatry, Division of Postgraduate Education, Boston, MA 02114, USA
    J Clin Psychiatry 69:1081-6. 2008
    ....
  21. pmc MTHFR 677C --> T genotype disrupts prefrontal function in schizophrenia through an interaction with COMT 158Val --> Met
    Joshua L Roffman
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 105:17573-8. 2008
    ..The findings also suggest the importance of weighing COMT effects on prefrontal function within the context of MTHFR genotype...
  22. ncbi request reprint Contribution of methylenetetrahydrofolate reductase (MTHFR) polymorphisms to negative symptoms in schizophrenia
    Joshua L Roffman
    Schizophrenia Research Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Biol Psychiatry 63:42-8. 2008
    ..We examined whether the methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C functional polymorphisms contribute to negative symptoms...
  23. ncbi request reprint Effects of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism on executive function in schizophrenia
    Joshua L Roffman
    Schizophrenia Research Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, USA
    Schizophr Res 92:181-8. 2007
    ..This study examined whether schizophrenia patients homozygous for the risk allele (T/T) exhibit greater impairment in executive function, and determined the extent to which MTHFR's effects on negative symptoms underlie this relationship...
  24. ncbi request reprint Increased medial temporal lobe activation during the passive viewing of emotional and neutral facial expressions in schizophrenia
    Daphne J Holt
    Massachusetts General Hospital, Department of Psychiatry, Harvard Medical School, Boston, MA 02129, USA
    Schizophr Res 82:153-62. 2006
    ..Here we tested whether MTL responses to human faces in schizophrenia are abnormal when unconstrained by a cognitive task and measured relative to a low-level baseline (fixation) condition...
  25. ncbi request reprint Sustained activation of the hippocampus in response to fearful faces in schizophrenia
    Daphne J Holt
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Biol Psychiatry 57:1011-9. 2005
    ..Using functional magnetic resonance imaging (fMRI), we tested the hypothesis that habituation of the medial temporal lobe is reduced in schizophrenia...
  26. ncbi request reprint Neuroimaging-genetic paradigms: a new approach to investigate the pathophysiology and treatment of cognitive deficits in schizophrenia
    Joshua L Roffman
    Harvard Medical School and Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02129, USA
    Harv Rev Psychiatry 14:78-91. 2006
    ..The potential of this approach for improving patient care will depend on its ability to predict outcomes with greater accuracy and sensitivity than current clinical measures...
  27. ncbi request reprint Hippocampal activation during processing of previously seen visual stimulus pairs
    Dost Ongur
    Schizophrenia and Bipolar Disorder Program, McLean Hospital, 115 Mill St, AB 347, Belmont, MA, USA
    Psychiatry Res 139:191-8. 2005
    ..Right hippocampal activation during discrimination of previously seen pairs of objects was correlated with activity in the anteromedial thalamus, cingulate cortex, and contralateral hippocampus...
  28. pmc Hippocampal and parahippocampal volumes in schizophrenia: a structural MRI study
    Kang Sim
    Schizophrenia and Bipolar Disorders Program, McLean Hospital Harvard Medical School, Mill Street, Belmont, MA, 02478, USA
    Schizophr Bull 32:332-40. 2006
    ..The finding of smaller medial temporal lobe volumes in the absence of regional specificity has important implications for studying the functional role of the hippocampus and surrounding cortical regions in schizophrenia...
  29. ncbi request reprint Impaired hippocampal recruitment during normal modulation of memory performance in schizophrenia
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02129, USA
    Biol Psychiatry 53:48-55. 2003
    ..We examined the effects of these interventions on both memory performance and retrieval-related hippocampal activity in healthy adults and patients with schizophrenia...
  30. ncbi request reprint Hippocampal and brain stem activation during word retrieval after repeated and semantic encoding
    Stephan Heckers
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Cambridge, MA, USA
    Cereb Cortex 12:900-7. 2002
    ..These findings confirm the importance of hippocampal recruitment during word retrieval and provide novel evidence for a role of brainstem neurons in word retrieval after semantic encoding...
  31. ncbi request reprint Magnetic resonance imaging-guided stereotactic limbic leukotomy for treatment of intractable psychiatric disease
    Alonso Montoya
    Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Neurosurgery 50:1043-9; discussion 1049-52. 2002
    ..To assess the efficacy and complication rates of magnetic resonance imaging-guided stereotactic limbic leukotomy for the treatment of intractable major depressive disorder (MDD) and obsessive-compulsive disorder (OCD)...
  32. ncbi request reprint Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for treatment of major depression
    Darin D Dougherty
    Department of Psychiatry, Radiology, Neurosurgery, and Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    J Neurosurg 99:1010-7. 2003
    ..The purpose of this study was to identify possible neuroimaging predictors of treatment response to anterior cingulotomy in patients with major depression...

Research Grants1

  1. Neural Correlates of Source Monitoring in Schizophrenia
    Anthony Weiss; Fiscal Year: 2007
    ..abstract_text> ..