Ajay Darsh Wasan

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Does report of craving opioid medication predict aberrant drug behavior among chronic pain patients?
    Ajay D Wasan
    Department of Anesthesia, Pain Management Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Clin J Pain 25:193-8. 2009
  2. pmc Craving of prescription opioids in patients with chronic pain: a longitudinal outcomes trial
    Ajay D Wasan
    Pain Management Center, Department of Anesthesiology, Perioperative and Pain Medicine, Harvard Medical School, Boston, Massachusetts, USA
    J Pain 13:146-54. 2012
  3. pmc Enhanced reactivity to pain in patients with rheumatoid arthritis
    Robert R Edwards
    Department of Anesthesiology, Harvard Medical School, Brigham and Women s Hospital, Chestnut Hill, MA 02467, USA
    Arthritis Res Ther 11:R61. 2009
  4. pmc The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: a cross-sectional study
    Yvonne C Lee
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, 75 Francis Street, PBB B3, Boston, MA 02115, USA
    Arthritis Res Ther 11:R160. 2009
  5. pmc Differences in pain, psychological symptoms, and gender distribution among patients with left- vs right-sided chronic spinal pain
    Ajay D Wasan
    Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Pain Med 11:1373-80. 2010
  6. pmc The impact of placebo, psychopathology, and expectations on the response to acupuncture needling in patients with chronic low back pain
    Ajay Darsh Wasan
    Department of Anesthesiology, Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    J Pain 11:555-63. 2010
  7. pmc Neural correlates of chronic low back pain measured by arterial spin labeling
    Ajay D Wasan
    Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Anesthesiology 115:364-74. 2011
  8. pmc Psychopathology predicts the outcome of medial branch blocks with corticosteroid for chronic axial low back or cervical pain: a prospective cohort study
    Ajay D Wasan
    Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    BMC Musculoskelet Disord 10:22. 2009
  9. ncbi request reprint Safety and efficacy of duloxetine in the treatment of diabetic peripheral neuropathic pain in older patients
    Ajay D Wasan
    Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Curr Drug Saf 4:22-9. 2009
  10. doi request reprint Reasons for participation in pain research: can they indicate a lack of informed consent?
    Ajay D Wasan
    Departments of Anesthesiology and Psychiatry, Harvard Medical School Brigham and Women s Hospital, Boston, Massachusetts, USA
    Pain Med 10:111-9. 2009

Research Grants

Detail Information

Publications25

  1. pmc Does report of craving opioid medication predict aberrant drug behavior among chronic pain patients?
    Ajay D Wasan
    Department of Anesthesia, Pain Management Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Clin J Pain 25:193-8. 2009
    ..To examine the relationship between the self-report of craving prescription medication and subsequent opioid misuse among chronic pain patients prescribed opioids for pain...
  2. pmc Craving of prescription opioids in patients with chronic pain: a longitudinal outcomes trial
    Ajay D Wasan
    Pain Management Center, Department of Anesthesiology, Perioperative and Pain Medicine, Harvard Medical School, Boston, Massachusetts, USA
    J Pain 13:146-54. 2012
    ..We found craving to be highly correlated with the urge to take more medication, fluctuations in mood, and preoccupation with the next dose, and to diminish with a behavioral intervention to improve opioid compliance...
  3. pmc Enhanced reactivity to pain in patients with rheumatoid arthritis
    Robert R Edwards
    Department of Anesthesiology, Harvard Medical School, Brigham and Women s Hospital, Chestnut Hill, MA 02467, USA
    Arthritis Res Ther 11:R61. 2009
    ..In the present study, we compared psychophysical and physiological responses to standardized noxious stimulation in 19 RA patients and 21 healthy controls...
  4. pmc The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: a cross-sectional study
    Yvonne C Lee
    Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, 75 Francis Street, PBB B3, Boston, MA 02115, USA
    Arthritis Res Ther 11:R160. 2009
    ..The etiology of RA pain is likely multifactorial, including both inflammatory and non-inflammatory components. In this study, we examine the association between disease activity, sleep, psychiatric distress and pain sensitivity in RA...
  5. pmc Differences in pain, psychological symptoms, and gender distribution among patients with left- vs right-sided chronic spinal pain
    Ajay D Wasan
    Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Pain Med 11:1373-80. 2010
    ..To determine pain levels, function, and psychological symptoms in relation to predominant sidedness of pain (right or left) and gender in patients being treated for chronic spinal pain...
  6. pmc The impact of placebo, psychopathology, and expectations on the response to acupuncture needling in patients with chronic low back pain
    Ajay Darsh Wasan
    Department of Anesthesiology, Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    J Pain 11:555-63. 2010
    ..Psychiatric comorbidity does not significantly impact acupuncture or placebo acupuncture analgesia in CLBP. It does not affect the positive impact of expectations on reported pain relief from real acupuncture...
  7. pmc Neural correlates of chronic low back pain measured by arterial spin labeling
    Ajay D Wasan
    Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Anesthesiology 115:364-74. 2011
    ..Arterial spin labeling is a perfusion-based imaging technique allowing the absolute quantification of regional cerebral blood flow, which is a surrogate measure of neuronal activity...
  8. pmc Psychopathology predicts the outcome of medial branch blocks with corticosteroid for chronic axial low back or cervical pain: a prospective cohort study
    Ajay D Wasan
    Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    BMC Musculoskelet Disord 10:22. 2009
    ..The objective of this study was to determine whether high levels of psychopathology are predictive of pain relief after MBB injections in the lumbar or cervical spine...
  9. ncbi request reprint Safety and efficacy of duloxetine in the treatment of diabetic peripheral neuropathic pain in older patients
    Ajay D Wasan
    Department of Anesthesiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Curr Drug Saf 4:22-9. 2009
    ..We present a post-hoc analysis of the safety and efficacy of duloxetine, a selective serotonin/norepinephrine reuptake inhibitor, for treatment of diabetic peripheral neuropathic pain (DPNP) in older patients...
  10. doi request reprint Reasons for participation in pain research: can they indicate a lack of informed consent?
    Ajay D Wasan
    Departments of Anesthesiology and Psychiatry, Harvard Medical School Brigham and Women s Hospital, Boston, Massachusetts, USA
    Pain Med 10:111-9. 2009
    ..This is the belief that research participation is equivalent to clinical care...
  11. doi request reprint Practice patterns and treatment choices among psychiatrists in New Delhi, India: a qualitative and quantitative study
    Ajay D Wasan
    Departments of Anesthesiology and Psychiatry, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
    Soc Psychiatry Psychiatr Epidemiol 44:109-19. 2009
    ..Little is known about the practice patterns of psychiatrists in India, such as daily practice routines or treatment approaches, which we describe in New Delhi, India...
  12. doi request reprint Interpreting urine drug tests: prevalence of morphine metabolism to hydromorphone in chronic pain patients treated with morphine
    Ajay D Wasan
    Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Pain Med 9:918-23. 2008
    ..We investigated whether hydromorphone may be a metabolite of morphine normally appearing in UDT of patients prescribed morphine...
  13. ncbi request reprint A case-matching study of the analgesic properties of electroconvulsive therapy
    Ajay D Wasan
    Department of Psychiatry and Anesthesiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Pain Med 5:50-8. 2004
    ..This study reports on the analgesia of ECT, controlling for treatment of depression...
  14. ncbi request reprint The association between negative affect and opioid analgesia in patients with discogenic low back pain
    Ajay D Wasan
    Brigham and Women s Hospital Harvard Medical School, Department of Anesthesiology, Pain Mangement Center, 850 Boylston Street, Chestnut Hill, MA 02467, USA
    Pain 117:450-61. 2005
    ..These results have implications for the prescription of oral opioids to patients with chronic low back pain and psychopathology...
  15. ncbi request reprint The association between psychopathology and placebo analgesia in patients with discogenic low back pain
    Ajay D Wasan
    Department of Anesthesiology, Brigham and Women s Hospital Harvard Medical School, Boston, Massachusetts 02467, USA
    Pain Med 7:217-28. 2006
    ..We previously found that psychopathology is associated with increased placebo analgesia in this patient group...
  16. ncbi request reprint Psychiatric history and psychologic adjustment as risk factors for aberrant drug-related behavior among patients with chronic pain
    Ajay D Wasan
    Pain Management Center, Department of Anesthesia, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02467, USA
    Clin J Pain 23:307-15. 2007
    ..To investigate the role of psychiatric history and psychologic adjustment on aberrant drug-related behavior among patients prescribed opioids for noncancer pain...
  17. ncbi request reprint Patients with chronic pain on opioid therapy taking dronabinol: incidence of false negatives using radioimmunoassay
    Sanjeet Narang
    Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Opioid Manag 4:21-6. 2008
    ..Serum blood toxicology screens are believed to be important to monitor compliance and to identify levels of illicit substances in patients taking opioids for their chronic pain...
  18. pmc Gender differences in risk factors for aberrant prescription opioid use
    Robert N Jamison
    Pain Management Center, Departments of Anesthesia and Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02467, USA
    J Pain 11:312-20. 2010
    ..These results suggest that risk factors associated with prescription opioid misuse may differ between men and women...
  19. pmc Substance misuse treatment for high-risk chronic pain patients on opioid therapy: a randomized trial
    Robert N Jamison
    Department of Anesthesiology, Pain Management Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02467, USA
    Pain 150:390-400. 2010
    ..05). The results of this study demonstrate support for the benefits of a brief behavioral intervention in the management of opioid compliance among chronic back pain patient at high-risk for prescription opioid misuse...
  20. ncbi request reprint Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy
    Sanjeet Narang
    Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Pain 9:254-64. 2008
    ..The results of our preliminary study suggest that dronabinol, a synthetic THC, may have an additive effect on pain relief...
  21. ncbi request reprint Dealing with difficult patients in your pain practice
    Ajay D Wasan
    Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Reg Anesth Pain Med 30:184-92. 2005
    ..Issues of comorbid psychopathology, hostility, suicidality, aberrant drug behavior, and chronic noncompliance are discussed. Specific recommendations are also given of the best ways to manage patients with difficult behavior...
  22. ncbi request reprint Urine toxicology screening among chronic pain patients on opioid therapy: frequency and predictability of abnormal findings
    Edward Michna
    Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Clin J Pain 23:173-9. 2007
    ..To examine the incidence of abnormal urine toxicology screening among chronic pain patients prescribed opioids for their pain and to relate these results to patient descriptors and type, number, and dose of prescribed opioids...
  23. ncbi request reprint Iatrogenic addiction in patients treated for acute or subacute pain: a systematic review
    Ajay D Wasan
    Department of Anesthesia, Perioperative and Pain Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Opioid Manag 2:16-22. 2006
    ..1 percent)...
  24. pmc Phase 1A safety assessment of intravenous amitriptyline
    Peter Fridrich
    Trauma Hospital, Lorenz Boehler, Vienna, and Department of Anesthesiology and Critical Care Medicine, Medical University Innsbruck, Austria
    J Pain 8:549-55. 2007
    ..As this occurs at very low plasma concentrations, a single preoperative intravenous infusion of amitriptyline could provide long-lasting pain relief and decrease the incidence of chronic pain...
  25. ncbi request reprint Comment on Ballantyne and LaForge, Opioid dependence and addiction during opioid treatment of chronic pain. Pain 2007;129:235-55
    Robert N Jamison
    Pain 132:218-9; author reply 219. 2007

Research Grants2

  1. Oral Opioid Treatment and Psychiatric Comorbidity
    Ajay Wasan; Fiscal Year: 2007
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