Rochelle Walensky

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Missed opportunities: refusal to confirm reactive rapid HIV tests in the emergency department
    Ishani Ganguli
    Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 8:e53408. 2013
  2. pmc HIV Self-testing and the Missing Linkage
    Rochelle P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS Med 8:e1001101. 2011
  3. pmc Combination HIV prevention: the value and interpretation of mathematical models
    Rochelle P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, 50 Staniford Street, 9th Floor, Boston, MA 02114, USA
    Curr HIV/AIDS Rep 10:195-8. 2013
  4. pmc The cost-effectiveness of pre-exposure prophylaxis for HIV infection in South African women
    Rochelle P Walensky
    Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 54:1504-13. 2012
  5. pmc Early infant HIV-1 diagnosis programs in resource-limited settings: opportunities for improved outcomes and more cost-effective interventions
    Andrea L Ciaranello
    Division of Infectious Disease, Massachusetts General Hospital, and Center for AIDS Research, Harvard Medical School, Boston, MA, USA
    BMC Med 9:59. 2011
  6. pmc Factors associated with refusal of rapid HIV testing in an emergency department
    Mary L Pisculli
    Division of Infectious Disease, Brigham and Women s Hospital, Boston, MA, USA
    AIDS Behav 15:734-42. 2011
  7. ncbi Rapid HIV testing at home: does it solve a problem or create one?
    Rochelle P Walensky
    Massachusetts General Hospital, Brigham and Women s Hospital, and the Center for AIDS Research, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ann Intern Med 145:459-62. 2006
  8. pmc HIV drug resistance surveillance for prioritizing treatment in resource-limited settings
    Rochelle P Walensky
    Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    AIDS 21:973-82. 2007
  9. pmc Cost-effectiveness of HIV testing and treatment in the United States
    Rochelle P Walensky
    Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 45:S248-54. 2007
  10. pmc Scaling up the 2010 World Health Organization HIV Treatment Guidelines in resource-limited settings: a model-based analysis
    Rochelle P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
    PLoS Med 7:e1000382. 2010

Research Grants

  1. Treatment Models for Primary and Chronic HIV Infection
    Rochelle Walensky; Fiscal Year: 2005
  2. Optimizing strategies for universal HIV testing
    Rochelle Walensky; Fiscal Year: 2006
  3. Optimizing strategies for universal HIV testing
    Rochelle Walensky; Fiscal Year: 2007
  4. Optimizing strategies for universal HIV testing
    Rochelle Walensky; Fiscal Year: 2009
  5. Optimizing strategies for universal HIV testing
    Rochelle P Walensky; Fiscal Year: 2010

Detail Information

Publications75

  1. pmc Missed opportunities: refusal to confirm reactive rapid HIV tests in the emergency department
    Ishani Ganguli
    Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 8:e53408. 2013
    ....
  2. pmc HIV Self-testing and the Missing Linkage
    Rochelle P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS Med 8:e1001101. 2011
    b>Rochelle Walensky and Ingrid Bassett discuss new research in <I>PLoS Medicine</I> that assessed the feasibility of home-based oral HIV self-testing in Malawi, and suggest that linkage to care must be demonstrated before the ..
  3. pmc Combination HIV prevention: the value and interpretation of mathematical models
    Rochelle P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, 50 Staniford Street, 9th Floor, Boston, MA 02114, USA
    Curr HIV/AIDS Rep 10:195-8. 2013
    ..Whether combination HIV prevention programs perform with additive, multiplicative or maximal effectiveness will be important to consider in anticipation of their combined transmission impact...
  4. pmc The cost-effectiveness of pre-exposure prophylaxis for HIV infection in South African women
    Rochelle P Walensky
    Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 54:1504-13. 2012
    ..PrEP's long-term impact on patient outcomes, population-level transmission, and cost-effectiveness remains unknown...
  5. pmc Early infant HIV-1 diagnosis programs in resource-limited settings: opportunities for improved outcomes and more cost-effective interventions
    Andrea L Ciaranello
    Division of Infectious Disease, Massachusetts General Hospital, and Center for AIDS Research, Harvard Medical School, Boston, MA, USA
    BMC Med 9:59. 2011
    ....
  6. pmc Factors associated with refusal of rapid HIV testing in an emergency department
    Mary L Pisculli
    Division of Infectious Disease, Brigham and Women s Hospital, Boston, MA, USA
    AIDS Behav 15:734-42. 2011
    ..Enrollment during morning hours was also associated with an increased risk of refusal. Increased educational efforts to convey the rationale and benefits of universal screening may improve testing uptake among these groups...
  7. ncbi Rapid HIV testing at home: does it solve a problem or create one?
    Rochelle P Walensky
    Massachusetts General Hospital, Brigham and Women s Hospital, and the Center for AIDS Research, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ann Intern Med 145:459-62. 2006
    ..S. citizens with unidentified HIV infection...
  8. pmc HIV drug resistance surveillance for prioritizing treatment in resource-limited settings
    Rochelle P Walensky
    Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    AIDS 21:973-82. 2007
    ..Sentinel testing programs for HIV drug resistance in resource-limited settings can inform policy on antiretroviral therapy (ART) and drug sequencing...
  9. pmc Cost-effectiveness of HIV testing and treatment in the United States
    Rochelle P Walensky
    Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 45:S248-54. 2007
    ..This article reviews the methods and results of cost-effectiveness studies in the United States and articulates why routine, voluntary HIV testing is not only of crucial public health importance but also economically justified...
  10. pmc Scaling up the 2010 World Health Organization HIV Treatment Guidelines in resource-limited settings: a model-based analysis
    Rochelle P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
    PLoS Med 7:e1000382. 2010
    ..This paper considers what to do first in resource-limited settings where immediate implementation of all of the WHO recommendations is not feasible...
  11. pmc Scaling up antiretroviral therapy in South Africa: the impact of speed on survival
    Rochelle P Walensky
    The Divisions of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    J Infect Dis 197:1324-32. 2008
    ..Only 33% of eligible human immunodeficiency virus (HIV)-infected patients in South Africa receive antiretroviral therapy (ART). We sought to estimate the impact of alternative ART scale-up scenarios on patient outcomes from 2007-2012...
  12. pmc Revising expectations from rapid HIV tests in the emergency department
    Rochelle P Walensky
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Ann Intern Med 149:153-60. 2008
    ..Expanded HIV screening efforts in the United States have increased the use of rapid HIV tests in emergency departments. The reported sensitivity and specificity of rapid HIV tests exceed 99%...
  13. pmc Cost-effectiveness of laboratory monitoring in sub-Saharan Africa: a review of the current literature
    Rochelle P Walensky
    Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 51:85-92. 2010
    ....
  14. pmc Test and treat DC: forecasting the impact of a comprehensive HIV strategy in Washington DC
    Rochelle P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 51:392-400. 2010
    ..We forecast outcomes of this approach if implemented in Washington DC...
  15. pmc The clinical impact and cost-effectiveness of routine, voluntary HIV screening in South Africa
    Rochelle P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    J Acquir Immune Defic Syndr 56:26-35. 2011
    ..Although 900,000 HIV-infected South Africans receive antiretroviral therapy, the majority of South Africans with HIV remain undiagnosed...
  16. pmc Counselor- versus provider-based HIV screening in the emergency department: results from the universal screening for HIV infection in the emergency room (USHER) randomized controlled trial
    Rochelle P Walensky
    Division of Infectious Diseases and General Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    Ann Emerg Med 58:S126-32.e1-4. 2011
    ..We compare rates of rapid HIV testing, test offer, and acceptance in an urban emergency department (ED) when conducted by dedicated HIV counselors versus current members of the ED staff...
  17. pmc Resource utilization and cost-effectiveness of counselor- vs. provider-based rapid point-of-care HIV screening in the emergency department
    Rochelle P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 6:e25575. 2011
    ..Routine HIV screening in emergency department (ED) settings may require dedicated personnel. We evaluated the outcomes, costs and cost-effectiveness of HIV screening when offered by either a member of the ED staff or by an HIV counselor...
  18. ncbi The survival benefits of AIDS treatment in the United States
    Rochelle P Walensky
    Division of Infectious Disease and General Medicine, Massachusetts General Hospital, Boston 02114, USA
    J Infect Dis 194:11-9. 2006
    ..As widespread adoption of potent combination antiretroviral therapy (ART) reaches its tenth year, our objective was to quantify the cumulative survival benefits of acquired immunodeficiency syndrome (AIDS) care in the United States...
  19. ncbi Investigation of primary human immunodeficiency virus infection in patients who test positive for heterophile antibody
    R P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Clin Infect Dis 33:570-2. 2001
    ..This study shows that false-positive results of heterophile tests are not frequently associated with primary HIV infection...
  20. ncbi Routine human immunodeficiency virus testing: an economic evaluation of current guidelines
    Rochelle P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, and the Partners AIDS Research Center, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Med 118:292-300. 2005
    ..Our objective was to evaluate the clinical effect and cost-effectiveness of current guidelines and of alternate HIV prevalence thresholds...
  21. ncbi Optimal allocation of testing dollars: the example of HIV counseling, testing, and referral
    Rochelle P Walensky
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    Med Decis Making 25:321-9. 2005
    ..Using the example of HIV testing, the authors explore the optimal targeting of funds within this pathway...
  22. pmc Effective HIV case identification through routine HIV screening at urgent care centers in Massachusetts
    Rochelle P Walensky
    Division of General Medicine, Massachusetts General Hospital, 50 Staniford St, 9th Floor, Boston, MA 02114, USA
    Am J Public Health 95:71-3. 2005
    ..Urgent care center-based routine HIV counseling, testing, and referral programs are feasible, can have high positive diagnosis yields, and should be the standard of care in high HIV prevalence areas...
  23. ncbi A therapeutic HIV vaccine: how good is good enough?
    Rochelle P Walensky
    Department of Medicine, Massachusetts General Hospital, and the Partners AIDS Research Center, Harvard Medical School, Boston, MA 02114, USA
    Vaccine 22:4044-53. 2004
    ..91 months (cost-effectiveness ratio US$ 45,500/QALY). Even modestly effective therapeutic HIV vaccines may produce small but meaningful increases in life expectancy and compare favorably to alternative uses of scarce HIV care resources...
  24. ncbi AIDS Drug Assistance Programs: highlighting inequities in human immunodeficiency virus-infection health care in the United States
    Rochelle P Walensky
    Division of Infectious Disease and the Partners AIDS Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Clin Infect Dis 35:606-10. 2002
    ..Cost-effectiveness analysis would offer a more informed basis for distribution of ADAP resources in an efficient and equitable manner, leading to a standardized national structure...
  25. ncbi Treatment for primary HIV infection: projecting outcomes of immediate, interrupted, or delayed therapy
    Rochelle P Walensky
    Division of Infectious Disease and the Partners AIDS Research Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    J Acquir Immune Defic Syndr 31:27-37. 2002
    ..These results can assist decision makers and those planning clinical trials in defining evidence-based performance measures for primary HIV infection treatment and future trials...
  26. ncbi Identifying undiagnosed human immunodeficiency virus: the yield of routine, voluntary inpatient testing
    Rochelle P Walensky
    Division of Infectious Disease and Partners AIDS Research Center, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, 50 Staniford St, Ninth Floor, Boston, MA 02114, USA
    Arch Intern Med 162:887-92. 2002
    ....
  27. pmc When to start antiretroviral therapy in resource-limited settings
    Rochelle P Walensky
    Massachusetts General Hospital, Brigham and Women s Hospital, Harvard University Medical School, Harvard School of Public Health, and Boston University School of Public Health, Boston, Massachusetts 02114, USA
    Ann Intern Med 151:157-66. 2009
    ..The results of international clinical trials that are assessing when to initiate antiretroviral therapy (ART) will not be available for several years...
  28. ncbi Cost-effectiveness of HIV treatment in resource-poor settings--the case of Côte d'Ivoire
    Sue J Goldie
    Department of Health Policy and Management, Program in Health Decision Science, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 355:1141-53. 2006
    ..As antiretroviral therapy is increasingly used in settings with limited resources, key questions about the timing of treatment and use of diagnostic tests to guide clinical decisions must be addressed...
  29. ncbi Effectiveness of antiretroviral therapy after protease inhibitor failure: an analytic overview
    Elena Losina
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    Clin Infect Dis 38:1613-22. 2004
    ..The best response was seen in NNRTI-naive patients receiving NNRTI- and boosted PI-containing regimens. New approaches are needed to achieve better suppression in pretreated HIV-infected patients...
  30. ncbi Projecting the cost-effectiveness of adherence interventions in persons with human immunodeficiency virus infection
    Sue J Goldie
    Center for Risk Analysis, Harvard School of Public Health, Boston, Massachusetts 02115 5924, USA
    Am J Med 115:632-41. 2003
    ..To explore the cost-effectiveness of interventions to improve adherence to combination antiretroviral therapy in patients with human immunodeficiency virus (HIV) infection...
  31. ncbi Cost-effectiveness of HIV interventions: from cohort studies and clinical trials to policy
    Rochelle P Walensky
    Harvard Medical School, Boston, MA, USA
    Top HIV Med 17:130-4. 2009
    ..This article is a summary of a presentation made by Rochelle P. Walensky, MD, MPH, at the International AIDS Society-USA Chicago program held in May 2009. The original presentation is available as a Webcast at www.iasusa.org...
  32. pmc Cost-effectiveness of preventing loss to follow-up in HIV treatment programs: a Côte d'Ivoire appraisal
    Elena Losina
    Division of General Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS Med 6:e1000173. 2009
    ..Our objective was to project the clinical impact and cost-effectiveness of interventions to prevent LTFU from HIV care in West Africa...
  33. ncbi Refusing HIV testing in an urgent care setting: results from the "Think HIV" program
    Rebecca V Liddicoat
    Department of Medicine, Greater Los Angeles Veterans Affairs, Los Angeles, California 90073, USA
    AIDS Patient Care STDS 20:84-92. 2006
    ..If routine HIV testing programs are to be successful, strategies must be developed to increase HIV test acceptance among patients most likely to refrain from testing...
  34. pmc HIV testing rates and outcomes in a South African community, 2001-2006: implications for expanded screening policies
    Michael D April
    Harvard Medical School, Boston, MA, USA
    J Acquir Immune Defic Syndr 51:310-6. 2009
    ..Revised World Health Organization recommendations seek to increase HIV testing. We assessed the need for expanded testing in South Africa by examining current testing and treatment trends among a high prevalence population...
  35. pmc Home testing for HIV infection in resource-limited settings
    Ishani Ganguli
    Division of General Medicine, Massachusetts General Hospital, 9th Floor, Boston, MA 02114, USA
    Curr HIV/AIDS Rep 6:217-23. 2009
    ..Home testing is showing promising early results in some high-prevalence, resource-limited settings. This article reviews the mechanisms and literature to date of this door-to-door approach...
  36. pmc Racial and sex disparities in life expectancy losses among HIV-infected persons in the united states: impact of risk behavior, late initiation, and early discontinuation of antiretroviral therapy
    Elena Losina
    Divisions of General Medicine, Department of Medicine, MA 02114, USA
    Clin Infect Dis 49:1570-8. 2009
    ....
  37. doi The impact of the President's Emergency Plan for AIDS Relief (PEPfAR) beyond HIV and why it remains essential
    Rochelle P Walensky
    Divisions of 1Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 50:272-5. 2010
    ..We further address the substantial impact PEPfAR has achieved in general and more specifically toward improving maternal and child health and why continued PEPfAR investment remains essential...
  38. pmc Who starts antiretroviral therapy in Durban, South Africa?... not everyone who should
    Ingrid V Bassett
    Division of Infectious Disease, Massachusetts General Hospital, Boston, MA 02114, USA
    AIDS 24:S37-44. 2010
    ..To evaluate rates of antiretroviral therapy (ART) initiation within 12 months of a new HIV diagnosis in Durban, South Africa...
  39. pmc Does modality of survey administration impact data quality: audio computer assisted self interview (ACASI) versus self-administered pen and paper?
    William M Reichmann
    Department of Orthopedic Surgery, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 5:e8728. 2010
    ..In the context of a randomized controlled trial (RCT) on HIV testing in the emergency department (ED) setting, we evaluated preferences for survey modality and data quality arising from each modality...
  40. pmc The "ART" of linkage: pre-treatment loss to care after HIV diagnosis at two PEPFAR sites in Durban, South Africa
    Elena Losina
    Division of General Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 5:e9538. 2010
    ..Our objective was to determine PTLC in newly identified HIV-infected individuals in South Africa...
  41. pmc Integrating HIV screening into routine health care in resource-limited settings
    Ingrid V Bassett
    Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 50:S77-84. 2010
    ..We review the benefits of knowledge of HIV serostatus and evidence from multiple countries surrounding the successes and pitfalls of provider-initiated testing in health care and home-based settings...
  42. pmc Intensive tuberculosis screening for HIV-infected patients starting antiretroviral therapy in Durban, South Africa
    Ingrid V Bassett
    Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts, USA
    Clin Infect Dis 51:823-9. 2010
    ..Our objective was to assess the yield and cost of a more intensive tuberculosis screening in HIV-infected patients starting antiretroviral therapy (ART) in Durban, South Africa...
  43. ncbi Two drugs or three? Balancing efficacy, toxicity, and resistance in postexposure prophylaxis for occupational exposure to HIV
    Ingrid V Bassett
    Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Clin Infect Dis 39:395-401. 2004
    ....
  44. pmc Predictors of mortality in patients initiating antiretroviral therapy in Durban, South Africa
    Bisola O Ojikutu
    Harvard Center for AIDS Research CFAR and Division of AIDS, Harvard Medical School, and Division of Infectious Disease, Massachusetts General Hospital, Boston, MA, USA
    S Afr Med J 98:204-8. 2008
    ..To identify predictors of mortality in patients initiating antiretroviral therapy (ART) in Durban, South Africa...
  45. pmc First-line antiretroviral therapy after single-dose nevirapine exposure in South Africa: a cost-effectiveness analysis of the OCTANE trial
    Andrea L Ciaranello
    Division of Infectious Disease, Massachusetts General Hospital, Boston, 02114, USA
    AIDS 25:479-92. 2011
    ..nevirapine-based antiretroviral therapy (ART) among women previously exposed to single-dose nevirapine to prevent mother-to-child HIV transmission. However, lopinavir/ritonavir is 12 times costlier than nevirapine...
  46. ncbi Review of human immunodeficiency virus type 1-related opportunistic infections in sub-Saharan Africa
    Charles B Holmes
    Division of Infectious Disease, Partners AIDS Research Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Clin Infect Dis 36:652-62. 2003
    ..Policies regarding the type and timing of opportunistic infection prophylaxis may be region specific and urgently require further study...
  47. pmc Effectiveness of pediatric antiretroviral therapy in resource-limited settings: a systematic review and meta-analysis
    Andrea L Ciaranello
    The Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 49:1915-27. 2009
    ..We sought to derive pooled estimates of the 12-month rate of virologic suppression (HIV RNA, <400 copies/mL) and gain in CD4 cell percentage (DeltaCD4%) for children initiating ART in resource-limited settings...
  48. pmc Cost-effectiveness of total knee arthroplasty in the United States: patient risk and hospital volume
    Elena Losina
    Department of Orthopedic Surgery, Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women s Hospital, Boston, MA 02115, USA
    Arch Intern Med 169:1113-21; discussion 1121-2. 2009
    ..However, to our knowledge, the cost-effectiveness of TKA and the influences of hospital volume and patient risk on TKA cost-effectiveness have not been investigated in the United States...
  49. pmc Visual screening for malignant melanoma: a cost-effectiveness analysis
    Elena Losina
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    Arch Dermatol 143:21-8. 2007
    ..To evaluate the cost-effectiveness of various melanoma screening strategies proposed in the United States...
  50. ncbi Optimizing resource allocation in United States AIDS drug assistance programs
    Benjamin P Linas
    Division of General Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Clin Infect Dis 43:1357-64. 2006
    ..We hypothesized that CD4 cell count-based ADAP eligibility would improve ADAP outcomes, allowing them to serve more-diverse patient populations and to prioritize persons who are at greatest risk of HIV-related mortality...
  51. ncbi Vesiculopapular rash
    Andrea L Ciaranello
    Division of Infectious Disease, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Infect Dis 43:1308, 1368-9. 2006
  52. pmc Cost-effectiveness of tenofovir as first-line antiretroviral therapy in India
    Melissa A Bender
    Divisions of General Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
    Clin Infect Dis 50:416-25. 2010
    ..We evaluated the clinical outcomes and cost-effectiveness of first-line ART using tenofovir in India, compared with current practice using stavudine or zidovudine...
  53. pmc Clinical impact and cost-effectiveness of antiretroviral therapy in India: starting criteria and second-line therapy
    Kenneth A Freedberg
    Divisions of General Medicine and Infectious Disease and the Partners AIDS Research Center, Massachusetts General Hospital, Boston, MA, USA
    AIDS 21:S117-28. 2007
    ..India has more than 5.7 million people infected with human immunodeficiency virus (HIV). In 2004, the Indian government began providing antiretroviral therapy (ART), and there are now an estimated 56 500 people receiving ART...
  54. pmc Routine voluntary HIV testing in Durban, South Africa: the experience from an outpatient department
    Ingrid V Bassett
    Division of Infectious Disease, Massachusetts General Hospital, Boston, MA 02114, USA
    J Acquir Immune Defic Syndr 46:181-6. 2007
    ..To evaluate the yield of a routine voluntary HIV testing program compared with traditional provider-referred voluntary counseling and testing (VCT) in a hospital-affiliated outpatient department (OPD) in Durban, South Africa...
  55. ncbi Optimizing treatment for HIV-infected South African women exposed to single-dose nevirapine: balancing efficacy and cost
    Charles B Holmes
    Divisions of Infectious Disease and General Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
    Clin Infect Dis 42:1772-80. 2006
    ..Our objectives were to project the tradeoffs regarding life expectancy, cost, and cost-effectiveness of these ART regimens for NVP-exposed, HIV-infected women in South Africa...
  56. ncbi Cost-effectiveness of enfuvirtide in treatment-experienced patients with advanced HIV disease
    Paul E Sax
    Division of Infectious Disease and the Partners AIDS Research Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Acquir Immune Defic Syndr 39:69-77. 2005
    ..Because of the high cost of ENF compared with other antiretroviral agents, our objectives were to determine the potential long-term clinical impact and cost-effectiveness of ENF in these patients...
  57. ncbi Optimal frequency of CD4 cell count and HIV RNA monitoring prior to initiation of antiretroviral therapy in HIV-infected patients
    April D Kimmel
    Division of General Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Antivir Ther 10:41-52. 2005
    ..Guidelines regarding the frequency of CD4 cell count and HIV RNA monitoring in HIV-infected patients vary, with recommended strategies ranging from every 2 to every 6 months...
  58. pmc Assessing the impact of federal HIV prevention spending on HIV testing and awareness
    Benjamin P Linas
    Massachusetts General Hospital, 50 Staniford St, Ninth Floor, Boston, MA 02114, USA
    Am J Public Health 96:1038-43. 2006
    ..The United States allocates more than $900 million annually for the prevention of HIV infection. We assessed the impact of this funding on HIV testing and knowledge...
  59. pmc HIV/AIDS: AIDS Drug Assistance Programs in the era of routine HIV testing
    Ingrid V Bassett
    Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Infect Dis 47:695-701. 2008
    ....
  60. ncbi Should resistance testing be performed for treatment-naive HIV-infected patients? A cost-effectiveness analysis
    Paul E Sax
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, MA 02115, USA
    Clin Infect Dis 41:1316-23. 2005
    ..Our objective was to determine the clinical impact and cost-effectiveness of genotype resistance testing for treatment-naive patients with chronic HIV infection...
  61. pmc Antiretroviral drugs for preventing mother-to-child transmission of HIV in sub-Saharan Africa: balancing efficacy and infant toxicity
    Andrea L Ciaranello
    Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    AIDS 22:2359-69. 2008
    ..We sought to identify the currently recommended regimen to prevent mother-to-child transmission that optimally balances risks of pediatric HIV infection and neurologic mitochondrial toxicity...
  62. pmc Access to medications and medical care after participation in HIV clinical trials: a systematic review of trial protocols and informed consent documents
    Andrea L Ciaranello
    Division of Infectious Disease, Massachusetts General Hospital, Boston, MA 02114, USA
    HIV Clin Trials 10:13-24. 2009
    ..We describe the frequency with which these posttrial services are described in the protocols and informed consent forms (ICFs) of antiretroviral drug (ARV) trials...
  63. pmc Loss to care and death before antiretroviral therapy in Durban, South Africa
    Ingrid V Bassett
    Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA
    J Acquir Immune Defic Syndr 51:135-9. 2009
    ..To examine the loss to care and mortality rates before starting antiretroviral therapy (ART) among ART eligible HIV-infected patients in Durban, South Africa...
  64. pmc Improving outcomes in state AIDS drug assistance programs
    Benjamin P Linas
    Divisions of General Medicine, Massachusetts General Hospital, Boston, MA 02115, USA
    J Acquir Immune Defic Syndr 51:513-21. 2009
    ..State AIDS Drug Assistance Programs (ADAPs) provide antiretroviral medications to patients with no access to medications. Resource constraints limit the ability of many ADAPs to meet demand for services...
  65. pmc Impact of obesity and knee osteoarthritis on morbidity and mortality in older Americans
    Elena Losina
    Brigham and Women s Hospital, Boston University School of Public Health, Massachusetts General Hospital, USA
    Ann Intern Med 154:217-26. 2011
    ..Obesity and knee osteoarthritis are among the most frequent chronic conditions affecting Americans aged 50 to 84 years...
  66. pmc Implementing a routine, voluntary HIV testing program in a Massachusetts county prison
    Rebecca V Liddicoat
    Department of Medicine, Greater Los Angeles Veterans Administration, Mail 111G, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA
    J Urban Health 83:1127-31. 2006
    ..Careful attention should be paid to prevent redundancy of testing efforts in the prison population. Implementing a routine HIV testing program among prison inmates greatly increased testing rates compared to on-request testing...
  67. pmc Beneficial and perverse effects of isoniazid preventive therapy for latent tuberculosis infection in HIV-tuberculosis coinfected populations
    Ted Cohen
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, One Brigham Circle, 1620 Tremont Street, Boston, MA 02120, USA
    Proc Natl Acad Sci U S A 103:7042-7. 2006
    ....
  68. pmc The effect of antiretroviral therapy on secondary transmission of HIV among men who have sex with men
    Alethea W McCormick
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Clin Infect Dis 44:1115-22. 2007
    ..However, the potential reduction in secondary transmission associated with ART may be offset by the longer duration of infectiousness...
  69. doi Monitoring of antiretroviral therapy in low-resource settings
    Rochelle P Walensky
    Lancet 372:288; author reply 289. 2008
  70. ncbi The lifetime cost of current human immunodeficiency virus care in the United States
    Bruce R Schackman
    Department of Public Health, Weill Medical College of Cornell University, New York, New York 10021, USA
    Med Care 44:990-7. 2006
    ..We sought to project the lifetime cost of medical care for human immunodefiency virus (HIV)-infected adults using current antiretroviral therapy (ART) standards...
  71. ncbi Expanded screening for HIV in the United States--an analysis of cost-effectiveness
    A David Paltiel
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, Conn 06520 8034, USA
    N Engl J Med 352:586-95. 2005
    ..The effect of expanded screening for HIV is unknown in the era of effective antiretroviral therapy...
  72. ncbi Expanded HIV screening in the United States: effect on clinical outcomes, HIV transmission, and costs
    A David Paltiel
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, Connecticut 06520 8034, USA
    Ann Intern Med 145:797-806. 2006
    ..An extensive literature supports expanded HIV screening in the United States. However, the question of whom to test and how frequently remains controversial...
  73. ncbi Clinical impact and cost-effectiveness of co-trimoxazole prophylaxis in patients with HIV/AIDS in Côte d'Ivoire: a trial-based analysis
    Yazdan Yazdanpanah
    Service Universitaire des Maladies Infectieuses et du Voyageur, Centre Hospitalier de Tourcoing, Faculte de Medecine de Lille, France
    AIDS 19:1299-308. 2005
    ..In 2000, WHO/UNAIDS recommended co-trimoxazole prophylaxis for persons at early stages of HIV infection (WHO stage > or = 2) in sub-Saharan Africa...
  74. ncbi APTIMA assay approved for HIV testing
    Rochelle P Walensky
    AIDS Clin Care 18:109-10. 2006
  75. ncbi Therapeutic drug monitoring in HIV treatment: a literature review
    Benjamin Z Wertheimer
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    HIV Clin Trials 7:59-69. 2006
    ..This intervention can potentially improve inadequate antiretroviral dosing in the treatment of HIV infection. Our objective was to review the evidence regarding TDM in HIV management...

Research Grants6

  1. Treatment Models for Primary and Chronic HIV Infection
    Rochelle Walensky; Fiscal Year: 2005
    ..b>Rochelle Walensky with a firm basis for career development as an independent, patient-oriented clinical researcher at the ..
  2. Optimizing strategies for universal HIV testing
    Rochelle Walensky; Fiscal Year: 2006
    ..The scientific basis for early detection of HIV infection and aggressive linkage to care has been successfully laid. The challenge now is to identify effective, affordable, and cost-effective implementation mechanisms. ..
  3. Optimizing strategies for universal HIV testing
    Rochelle Walensky; Fiscal Year: 2007
    ..The scientific basis for early detection of HIV infection and aggressive linkage to care has been successfully laid. The challenge now is to identify effective, affordable, and cost-effective implementation mechanisms. ..
  4. Optimizing strategies for universal HIV testing
    Rochelle Walensky; Fiscal Year: 2009
    ..The scientific basis for early detection of HIV infection and aggressive linkage to care has been successfully laid. The challenge now is to identify effective, affordable, and cost-effective implementation mechanisms. ..
  5. Optimizing strategies for universal HIV testing
    Rochelle P Walensky; Fiscal Year: 2010
    ..The scientific basis for early detection of HIV infection and aggressive linkage to care has been successfully laid. The challenge now is to identify effective, affordable, and cost-effective implementation mechanisms. ..