Aleksandr Vasilyev

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Mechanical stretch and PI3K signaling link cell migration and proliferation to coordinate epithelial tubule morphogenesis in the zebrafish pronephros
    Aleksandr Vasilyev
    Department of Pathology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
    PLoS ONE 7:e39992. 2012
  2. pmc Fluid flow and guidance of collective cell migration
    Aleksandr Vasilyev
    Pathology Department, Massachusetts General Hospital, Charlestown, MA, USA
    Cell Adh Migr 4:353-7. 2010
  3. pmc odd skipped related1 reveals a novel role for endoderm in regulating kidney versus vascular cell fate
    Sudha P Mudumana
    Nephrology Division, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Development 135:3355-67. 2008
  4. pmc The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation
    Steve Mangos
    Massachusetts General Hospital, Department of Medicine, Nephrology Division, and Harvard Medical School Department of Genetics, Charlestown, MA 02129, USA
    Dis Model Mech 3:354-65. 2010
  5. pmc Cytoplasmic carboxypeptidase 5 regulates tubulin glutamylation and zebrafish cilia formation and function
    Narendra Pathak
    Nephrology Division, Massachusetts General Hospital, Charlestown, MA 02129
    Mol Biol Cell 25:1836-44. 2014
  6. pmc Collective cell migration drives morphogenesis of the kidney nephron
    Aleksandr Vasilyev
    Nephrology Division, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    PLoS Biol 7:e9. 2009
  7. doi Live imaging kidney development in zebrafish
    Aleksandr Vasilyev
    Nephrology Division and Department of Pathology, Charlestown, MA, USA
    Methods Mol Biol 886:55-70. 2012
  8. ncbi Collective epithelial migration drives kidney repair after acute injury
    Aurélien Palmyre
    Nephrology Division, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 9:e101304. 2014
  9. ncbi A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12
    Alexa Burger
    Cancer Center, Massachusetts General Hospital, Charlestown, MA 02129, USA Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA
    Dis Model Mech 7:907-13. 2014
  10. pmc Altered leukotriene B4 metabolism in CYP4F18-deficient mice does not impact inflammation following renal ischemia
    Valeria Winslow
    Nephrology Division, Department of Medicine, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Biochim Biophys Acta 1841:868-79. 2014

Collaborators

  • Troy Camarata
  • Vladimir Korzh
  • Igor Kondrychyn
  • Iain A Drummond
  • Yan Liu
  • Martin K Selig
  • Narendra Pathak
  • Valeria Winslow
  • Alexa Burger
  • Aurélien Palmyre
  • Steve Mangos
  • Sudha P Mudumana
  • Justin Drake
  • Peter Christmas
  • Ritu Tomar
  • Christina A Austin-Tse
  • Anne Laure Duchemin
  • G Petur Nielsen
  • Ivaylo Stoilov
  • Daniel A Haber
  • Paul Nowak
  • Christopher Stark
  • Randall T Peterson
  • Gennadiy Ryklin
  • Karim Douaidy
  • Jeongeun Lee
  • David Dombkowski
  • Rachel Vaivoda
  • M Amin Arnaout
  • Dharamainder Choudhary
  • Frederic Preffer
  • Evin Guilliams
  • Angela Zhao
  • Aiping Liu
  • Pui Ying Lam
  • Sudha Mudumana
  • Dirk Hentschel

Detail Information

Publications10

  1. pmc Mechanical stretch and PI3K signaling link cell migration and proliferation to coordinate epithelial tubule morphogenesis in the zebrafish pronephros
    Aleksandr Vasilyev
    Department of Pathology, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
    PLoS ONE 7:e39992. 2012
    ....
  2. pmc Fluid flow and guidance of collective cell migration
    Aleksandr Vasilyev
    Pathology Department, Massachusetts General Hospital, Charlestown, MA, USA
    Cell Adh Migr 4:353-7. 2010
    ..Intratubular migration leads to significant changes in kidney morphology. This novel process provides a powerful in vivo model for further exploration of the mechanisms underlying mechanotransduction and collective migration...
  3. pmc odd skipped related1 reveals a novel role for endoderm in regulating kidney versus vascular cell fate
    Sudha P Mudumana
    Nephrology Division, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Development 135:3355-67. 2008
    ....
  4. pmc The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation
    Steve Mangos
    Massachusetts General Hospital, Department of Medicine, Nephrology Division, and Harvard Medical School Department of Genetics, Charlestown, MA 02129, USA
    Dis Model Mech 3:354-65. 2010
    ..Our results suggest that pkd1a/b and pkd2 interact to regulate ECM secretion or assembly, and that altered matrix integrity may be a primary defect underlying ADPKD tissue pathologies...
  5. pmc Cytoplasmic carboxypeptidase 5 regulates tubulin glutamylation and zebrafish cilia formation and function
    Narendra Pathak
    Nephrology Division, Massachusetts General Hospital, Charlestown, MA 02129
    Mol Biol Cell 25:1836-44. 2014
    ....
  6. pmc Collective cell migration drives morphogenesis of the kidney nephron
    Aleksandr Vasilyev
    Nephrology Division, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    PLoS Biol 7:e9. 2009
    ..Our results establish intimate links between nephron function, fluid flow, and morphogenesis...
  7. doi Live imaging kidney development in zebrafish
    Aleksandr Vasilyev
    Nephrology Division and Department of Pathology, Charlestown, MA, USA
    Methods Mol Biol 886:55-70. 2012
    ..Here, we describe a simple procedure that can be used by laboratories to investigate the development of zebrafish kidney and other organs by time-lapse microscopy...
  8. ncbi Collective epithelial migration drives kidney repair after acute injury
    Aurélien Palmyre
    Nephrology Division, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 9:e101304. 2014
    ..Overall, this study advances our understanding of kidney repair mechanisms by highlighting a primary role for collective cell migration, laying a foundation for new approaches to treatment of AKI. ..
  9. ncbi A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12
    Alexa Burger
    Cancer Center, Massachusetts General Hospital, Charlestown, MA 02129, USA Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA
    Dis Model Mech 7:907-13. 2014
    ..Consequently, the HRASV12-driven zebrafish model of chordoma could enable high-throughput screening of potential therapeutic agents for the treatment of this refractory cancer. ..
  10. pmc Altered leukotriene B4 metabolism in CYP4F18-deficient mice does not impact inflammation following renal ischemia
    Valeria Winslow
    Nephrology Division, Department of Medicine, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Biochim Biophys Acta 1841:868-79. 2014
    ....