Research Topics
Species | Alexander TurchinSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
Research Grants
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Detail Information
Publications
Documentation of body mass index and control of associated risk factors in a large primary care networkStephanie A Rose
Division of General Internal Medicine, University of Kentucky, 740 South Limestone Street, Kentucky Clinic K507, Lexington, KY 40536, USA
BMC Health Serv Res 9:236. 2009..We evaluated current documentation of BMI, and documentation and control of associated risk factors by BMI category, based on electronic health records from a 12-clinic primary care network...
Clinical problem-solving. Mind the gapAlexander Turchin
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Boston 02115, USA
N Engl J Med 349:1465-9. 2003
Effectiveness of interruptive alerts in increasing application functionality utilization: a controlled trialAlexander Turchin
Clinical Informatics Research and Development, Partners HealthCare, Boston, MA, USA
J Biomed Inform 44:463-8. 2011..0001). Alerts led to a nearly 2-fold increase in utilization of the promoted functionalities. Interruptive alerts are an effective method of delivering information about application functionalities to users...
Encounter frequency and blood pressure in hypertensive patients with diabetes mellitusAlexander Turchin
Division of Endocrinology, Brigham and Women s Hospital, 221 Longwood Ave, Boston, MA 02115, USA
Hypertension 56:68-74. 2010..Greatest benefits were observed at encounter intervals (<or=2 weeks) shorter than what is currently recommended...
Hypoglycemia and clinical outcomes in patients with diabetes hospitalized in the general wardAlexander Turchin
Brigham and Women s Hospital, Boston, Massachusetts, USA
Diabetes Care 32:1153-7. 2009..In this study, we aimed to determine whether hypoglycemic episodes are associated with higher mortality in diabetic patients hospitalized in the general ward...
Comparison of information content of structured and narrative text data sources on the example of medication intensificationAlexander Turchin
Clinical Informatics Research and Development, Suite 201, 93 Worcester St, Wellesley, MA 02481, USA
J Am Med Inform Assoc 16:362-70. 2009..Clinical validity of information in both sources was demonstrated by correlation with changes in blood pressure...
Evaluation of an inpatient computerized medication reconciliation systemAlexander Turchin
Brigham and Women s Hospital, Boston, MA, USA
J Am Med Inform Assoc 15:449-52. 2008..Most users agreed that medication reconciliation improves patient care but requested tighter integration of the different stages of the medication reconciliation process. Further training may be helpful in improving user efficiency...
Effect of board certification on antihypertensive treatment intensification in patients with diabetes mellitusAlexander Turchin
Division of Endocrinology, Brigham and Women s Hospital, 221 Longwood Ave, Boston, MA 02115, USA
Circulation 117:623-8. 2008..We therefore carried out a study to determine whether the frequency of antihypertensive treatment intensification for diabetic patients changes with time since their physicians' last board certification...
The use of electronic medication reconciliation to establish the predictors of validity of computerized medication recordsAlexander Turchin
Clinical Informatics Research and Development, Partners HealthCare, Boston, MA, USA
Stud Health Technol Inform 129:1022-6. 2007..Several characteristics of electronic medication records are strongly associated with their validity. These findings could be incorporated in the design of CIS software to alert providers to medication records less likely to be accurate...
Identification of patients with diabetes from the text of physician notes in the electronic medical recordAlexander Turchin
Division of Endocrinology, BrighamWomen's Hospital, Boston, MA 02115, USA
Diabetes Care 28:1794-5. 2005
Computational analysis of non-adherence and non-attendance using the text of narrative physician notes in the electronic medical recordAlexander Turchin
Division of Endocrinology, Brigham and Women s Hospital, Boston, MA 02115, USA
Med Inform Internet Med 32:93-102. 2007..This approach has been validated at several levels and demonstrated to correlate with clinical outcomes...
Relationship of physician volume with process measures and outcomes in diabetesAlexander Turchin
Division of Endocrinology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Diabetes Care 30:1442-7. 2007..It is not known whether a similar association exists for treatment of diabetes. In this study we aimed to determine whether physician volume is associated with improved process measures and outcomes in diabetes care...
Severe hypercholesterolemia mediated by lipoprotein X in patients with chronic graft-versus-host disease of the liverA Turchin
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, MA 02115, USA
Bone Marrow Transplant 35:85-9. 2005..It is important for clinicians to familiarize themselves with the diagnostic and therapeutic challenges this condition presents...
Using regular expressions to abstract blood pressure and treatment intensification information from the text of physician notesAlexander Turchin
Clinical Informatics Research and Development, Partners HealthCare System, 93 Worcester Street, Suite 201, Wellesley, MA 02481, USA
J Am Med Inform Assoc 13:691-5. 2006..8%, specificity of 95.0%, and precision of 85.9%. Regular expressions can be an effective method for focused information extraction tasks related to high-priority disease areas such as hypertension...
Effect of acute aldosterone administration on gene expression profile in the heartAlexander Turchin
Division of Endocrinology, Brigham and Women s Hospital, 221 Longwood Avenue, Boston, Massachusetts 02115, USA
Endocrinology 147:3183-9. 2006..These results provide the first description of cardiac genetic response to aldosterone and identify several potential mediators of known biochemical sequelae of aldosterone administration in the heart...
Effect of an electronic medication reconciliation application and process redesign on potential adverse drug events: a cluster-randomized trialJeffrey L Schnipper
Harvard Medical School, Division of General Medicine, Brigham and Women s Hospital, 1620 Tremont St, Boston, MA 02120 1613, USA
Arch Intern Med 169:771-80. 2009..We sought to measure the impact of an information technology-based medication reconciliation intervention on medication discrepancies with potential for harm (potential adverse drug events [PADEs])...
Prevalence and factors affecting home blood pressure documentation in routine clinical care: a retrospective studyMichael H Kramer
Department of Computer Science, Harvard College, Cambridge, MA, USA
BMC Health Serv Res 10:139. 2010..However, the prevalence of its documentation has not been examined. The objective of this study was to analyze the prevalence and factors affecting documentation of home BP in routine clinical care...
Development of a tool within the electronic medical record to facilitate medication reconciliation after hospital dischargeJeffrey L Schnipper
Brigham and Women s Hospital Hospitalist Service, Brigham and Women s Hospital, Boston, Massachusetts, USA
J Am Med Inform Assoc 18:309-13. 2011..Review of feedback identified several usability issues that will inform subsequent versions of the tool and provide generalizable lessons for how best to design medication reconciliation tools for this setting...
Treatment intensification and blood glucose control among hospitalized diabetic patientsMichael E Matheny
Decision Systems Group, Brigham and Women s Hospital, Boston, MA 02115, USA
J Gen Intern Med 23:184-9. 2008..We evaluated the relationship between treatment intensification and changes in blood glucose in hospitalized diabetic patients...
Encounter frequency and serum glucose level, blood pressure, and cholesterol level control in patients with diabetes mellitusFritha Morrison
Division of Endocrinology, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Ave, Boston, MA 02115, USA
Arch Intern Med 171:1542-50. 2011....
Design and implementation of an application and associated services to support interdisciplinary medication reconciliation efforts at an integrated healthcare delivery networkEric G Poon
Clinical Informatics Research and Development, Suite 201, 93 Worcester St, Wellesley, MA 02481, USA
J Am Med Inform Assoc 13:581-92. 2006..Results from early pilot testing suggest that this new medication reconciliation process is well accepted by clinicians and has significant potential to prevent medication errors during transitions of care...
Classifying and predicting errors of inpatient medication reconciliationJennifer R Pippins
Division of General Medicine, Brigham and Women s Hospital, Boston, MA 02120 1613, USA
J Gen Intern Med 23:1414-22. 2008..Failure to reconcile medications across transitions in care is an important source of potential harm to patients. Little is known about the predictors of unintentional medication discrepancies and how, when, and where they occur...
Lifestyle counseling in routine care and long-term glucose, blood pressure, and cholesterol control in patients with diabetesFritha Morrison
Division of Endocrinology, Brigham and Women s Hospital, Boston, Massachusetts, USA
Diabetes Care 35:334-41. 2012..However, little is known about the long-term effects of lifestyle counseling on patients with diabetes in routine clinical settings...
An unintended consequence of electronic prescriptions: prevalence and impact of internal discrepanciesMatvey B Palchuk
Harvard Medical School, Boston, Massachusetts, USA
J Am Med Inform Assoc 17:472-6. 2010..Improvements in electronic medical record design are necessary to minimize the risk of discrepancies and resulting adverse events...
Activation of the mineralocorticoid receptor increases striatin levelsLuminita H Pojoga
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Hypertens 25:243-9. 2012..Striatin, a membrane associated protein, interacts with estrogen receptors in endothelial cells...
Routinely measuring and reporting pneumococcal vaccination among immunosuppressed rheumatology outpatients: the first step in improving qualitySonali P Desai
Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
Rheumatology (Oxford) 50:366-72. 2011..Data suggest that rates of vaccination in this population are not optimal. To support continuous quality improvement efforts, we electronically measured vaccination status among rheumatology outpatients over time...
Increasing pneumococcal vaccination for immunosuppressed patients: A cluster quality improvement trialSonali P Desai
Brigham and Women s Hospital, Boston, Massachusetts
Arthritis Rheum 65:39-47. 2013....
Lexical concept distribution reflects clinical practiceEugene Breydo
Quality Performance Management, Partners HealthCare, Boston, MA
AMIA Annu Symp Proc 2012:61-6. 2012..These findings provide evidence that narrative medical documents directly reflect clinical practice and constitute a valid source of medical data...
"Summary Page": a novel tool that reduces omitted data in research databasesSaveli I Goldberg
Massachusetts General Hospital, Boston, MA, USA
BMC Med Res Methodol 10:91. 2010..Omitted data are of particular concern because they are more common than erroneously inserted data and therefore could potentially affect research findings. However, few affordable strategies for their prevention are available...
Structured vs. unstructured: factors affecting adverse drug reaction documentation in an EMR repositoryStephen Skentzos
Brigham and Women s Hospital, Inc, Boston, MA, USA
AMIA Annu Symp Proc 2011:1270-9. 2011..6, p < 0.0001). Integration of information flow between EMR modules can help improve documentation and potentially prevent adverse drug events...
Unexpected effects of unintended consequences: EMR prescription discrepancies and hemorrhage in patients on warfarinAlexander Turchin
Partners HealthCare System, Inc, Boston, MA, USA
AMIA Annu Symp Proc 2011:1412-7. 2011..045) compared to controls.Consequences of EMR errors may not be obvious. Studies that directly examine clinical outcomes are necessary to identify categories of EMR errors likely to cause patient harm...
Building a departmental quality program: a patient-based and provider-led approachLara E Szent-Gyorgyi
Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Acad Med 86:314-20. 2011..The program's system-based focus encourages providers to develop solutions within the existing framework of clinic resources, primarily targeting work flows and processes, while minimizing large expenditures on additional staffing...
An algorithm for the care of type 2 diabetesAlan Cole
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Crit Pathw Cardiol 8:156-65. 2009..Additional teaching is provided in the form of frequently asked questions answered by domain experts...
Research Grants
- Monitoring Intensification of Treatment for Hyperglycemia and HyperlipidemiaAlexander Turchin; Fiscal Year: 2007....
