Jennifer S Temel

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Complexities of quality of life analysis in non-small cell lung cancer
    Jennifer Temel
    Harvard Medical School, Boston, Massachusetts, USA
    J Support Oncol 5:30-1. 2007
  2. ncbi request reprint Phase II study: integrated palliative care in newly diagnosed advanced non-small-cell lung cancer patients
    Jennifer S Temel
    Massachusetts General Hospital, Boston, MA 02114, USA
    J Clin Oncol 25:2377-82. 2007
  3. ncbi request reprint Electronic prompt to improve outpatient code status documentation for patients with advanced lung cancer
    Jennifer S Temel
    Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA
    J Clin Oncol 31:710-5. 2013
  4. doi request reprint Early palliative care for patients with metastatic non-small-cell lung cancer
    Jennifer S Temel
    Massachusetts General Hospital, Boston, MA 02114, USA
    N Engl J Med 363:733-42. 2010
  5. doi request reprint Longitudinal perceptions of prognosis and goals of therapy in patients with metastatic non-small-cell lung cancer: results of a randomized study of early palliative care
    Jennifer S Temel
    Massachusetts GeneralHospital Cancer Center, 55 Fruit Street, Massachusetts General Hospital, Boston, MA 02114, USA
    J Clin Oncol 29:2319-26. 2011
  6. pmc Code status documentation in the outpatient electronic medical records of patients with metastatic cancer
    Jennifer S Temel
    Massachusetts General Hospital Cancer Center, 55 Fruit Street, Yawkey 7B, Boston, MA 02114, USA
    J Gen Intern Med 25:150-3. 2010
  7. pmc A structured exercise program for patients with advanced non-small cell lung cancer
    Jennifer S Temel
    Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Thorac Oncol 4:595-601. 2009
  8. ncbi request reprint Can weight loss at presentation predict patient outcome in lung cancer?
    Jennifer Temel
    Massachusetts General Hospital, MA, USA
    Nat Clin Pract Oncol 1:68-9. 2004
  9. doi request reprint Aggressiveness of care in a prospective cohort of patients with advanced NSCLC
    Jennifer S Temel
    Department of Hematology Oncology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Cancer 113:826-33. 2008
  10. ncbi request reprint Comprehensive symptom management in patients with advanced-stage non-small-cell lung cancer
    Jennifer S Temel
    Department of Medicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Lung Cancer 7:241-9. 2006

Research Grants

Detail Information

Publications50

  1. ncbi request reprint Complexities of quality of life analysis in non-small cell lung cancer
    Jennifer Temel
    Harvard Medical School, Boston, Massachusetts, USA
    J Support Oncol 5:30-1. 2007
  2. ncbi request reprint Phase II study: integrated palliative care in newly diagnosed advanced non-small-cell lung cancer patients
    Jennifer S Temel
    Massachusetts General Hospital, Boston, MA 02114, USA
    J Clin Oncol 25:2377-82. 2007
    ..To assess the feasibility of early palliative care in the ambulatory setting in patients with newly diagnosed advanced non-small-cell lung cancer (NSCLC)...
  3. ncbi request reprint Electronic prompt to improve outpatient code status documentation for patients with advanced lung cancer
    Jennifer S Temel
    Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA
    J Clin Oncol 31:710-5. 2013
    ....
  4. doi request reprint Early palliative care for patients with metastatic non-small-cell lung cancer
    Jennifer S Temel
    Massachusetts General Hospital, Boston, MA 02114, USA
    N Engl J Med 363:733-42. 2010
    ..We examined the effect of introducing palliative care early after diagnosis on patient-reported outcomes and end-of-life care among ambulatory patients with newly diagnosed disease...
  5. doi request reprint Longitudinal perceptions of prognosis and goals of therapy in patients with metastatic non-small-cell lung cancer: results of a randomized study of early palliative care
    Jennifer S Temel
    Massachusetts GeneralHospital Cancer Center, 55 Fruit Street, Massachusetts General Hospital, Boston, MA 02114, USA
    J Clin Oncol 29:2319-26. 2011
    ..The aims of this study were to explore perceptions of prognosis and goals of therapy in patients with metastatic non-small-cell lung cancer (NSCLC) and to examine the effect of early palliative care on these views over time...
  6. pmc Code status documentation in the outpatient electronic medical records of patients with metastatic cancer
    Jennifer S Temel
    Massachusetts General Hospital Cancer Center, 55 Fruit Street, Yawkey 7B, Boston, MA 02114, USA
    J Gen Intern Med 25:150-3. 2010
    ..However, little is known about clinical practices in outpatient oncology settings related to discussing end-of-life care and documenting code status preferences in ambulatory medical records...
  7. pmc A structured exercise program for patients with advanced non-small cell lung cancer
    Jennifer S Temel
    Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Thorac Oncol 4:595-601. 2009
    ..In this study, we examined the feasibility of a hospital-based exercise program for patients with advanced non-small cell lung cancer...
  8. ncbi request reprint Can weight loss at presentation predict patient outcome in lung cancer?
    Jennifer Temel
    Massachusetts General Hospital, MA, USA
    Nat Clin Pract Oncol 1:68-9. 2004
  9. doi request reprint Aggressiveness of care in a prospective cohort of patients with advanced NSCLC
    Jennifer S Temel
    Department of Hematology Oncology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Cancer 113:826-33. 2008
    ..Optimal end of life care of patients with terminal cancer is poorly understood. In this study, the aggressiveness of care is described in a cohort of patients with newly diagnosed advanced nonsmall-cell lung cancer (NSCLC)...
  10. ncbi request reprint Comprehensive symptom management in patients with advanced-stage non-small-cell lung cancer
    Jennifer S Temel
    Department of Medicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Lung Cancer 7:241-9. 2006
    ..Therefore, comprehensive care of patients with advanced-stage NSCLC must include therapies targeted at these difficult and distressing symptoms...
  11. ncbi request reprint Feasibility and validity of a one-item fatigue screen in a thoracic oncology clinic
    Jennifer S Temel
    Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Thorac Oncol 1:454-9. 2006
    ..Despite its high prevalence, it is often unrecognized and undetected. This study assessed the feasibility and validity of a one-item fatigue scale (OIFS) in an outpatient oncology clinic...
  12. pmc Depression and survival in metastatic non-small-cell lung cancer: effects of early palliative care
    William F Pirl
    Massachusetts General Hospital Cancer Center, Center for Psychiatric Oncology and Behavioral Sciences, Yawkey 9A, 55 Fruit St, Boston, MA 02114, USA
    J Clin Oncol 30:1310-5. 2012
    ..In a secondary analysis, we explored the hypothesis that the survival benefit resulted from improving depression...
  13. doi request reprint The cultivation of prognostic awareness through the provision of early palliative care in the ambulatory setting: a communication guide
    Vicki A Jackson
    Division of Palliative Care, Massachusetts General Hospital, Boston, Massachusetts 02114, USA partners org
    J Palliat Med 16:894-900. 2013
    ..This approach can be used by both novice and more experienced palliative care clinicians...
  14. doi request reprint Depression, survival, and epidermal growth factor receptor genotypes in patients with metastatic non-small cell lung cancer
    William F Pirl
    Center for Psychiatric Oncology and Behavioral Sciences, Massachusetts General Hospital Cancer Center, Boston, MA, USA
    Palliat Support Care 11:223-9. 2013
    ..We investigated this possible relationship in a cohort of patients with metastatic NSCLC, in which we had previously demonstrated an association between depression and worse survival...
  15. ncbi request reprint Associations among prognostic understanding, quality of life, and mood in patients with advanced cancer
    Areej El-Jawahri
    Division of Hematology Oncology, Massachusetts General Hospital, Boston, Massachusetts
    Cancer 120:278-85. 2014
    ..The objectives of this study were to assess perceptions of prognosis and preferences for prognostic information among patients with advanced cancer and to explore the associations of prognostic understanding with QoL and mood...
  16. doi request reprint Effect of early palliative care on chemotherapy use and end-of-life care in patients with metastatic non-small-cell lung cancer
    Joseph A Greer
    Massachusetts General Hospital Cancer Center, Yawkey Building, Suite 9A, 55 Fruit St, Boston, MA 02114, USA
    J Clin Oncol 30:394-400. 2012
    ..We sought to investigate whether early palliative care also affects the frequency and timing of chemotherapy use and hospice care for these patients...
  17. pmc A pilot randomized controlled trial of brief cognitive-behavioral therapy for anxiety in patients with terminal cancer
    Joseph A Greer
    Center for Psychiatric Oncology and Behavioral Sciences, Massachusetts General Hospital Cancer Center, Yawkey Building, Suite 10B, 55 Fruit Street, Boston, Massachusetts 02114, USA
    Oncologist 17:1337-45. 2012
    ..In this pilot randomized controlled trial (clinicaltrials.gov identifier NCT00706290), we examined the feasibility and potential efficacy of brief CBT to reduce anxiety in patients with terminal cancer...
  18. ncbi request reprint Early palliative care in advanced lung cancer: a qualitative study
    Jaclyn Yoong
    Massachusetts General Hospital, Boston, MA 02114, USA
    JAMA Intern Med 173:283-90. 2013
    ..During critical clinical time points, PC and oncologic care visits have distinct features that suggest a key role for PC involvement and enable oncologists to focus on cancer treatment and managing medical complications...
  19. doi request reprint Phase I/II study of AT-101 with topotecan in relapsed and refractory small cell lung cancer
    Rebecca Suk Heist
    Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Thorac Oncol 5:1637-43. 2010
    ..AT-101 is an oral, pan Bcl-2 family protein inhibitor that has demonstrated activity in small cell lung cancer (SCLC) models. A phase I/II study was conducted combining AT-101 with topotecan in relapsed and refractory SCLC...
  20. pmc A phase I study of erlotinib and hydroxychloroquine in advanced non-small-cell lung cancer
    Sarah B Goldberg
    Massachusetts General Hospital Cancer Center, Boston, MA, USA
    J Thorac Oncol 7:1602-8. 2012
    ..This investigator-initiated study explores the safety, maximum tolerated dose, clinical response, and pharmacokinetics of hydroxychloroquine (HCQ) with and without erlotinib in patients with advanced non-small-cell lung cancer...
  21. doi request reprint Depression after diagnosis of advanced non-small cell lung cancer and survival: a pilot study
    William F Pirl
    Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA
    Psychosomatics 49:218-24. 2008
    ..Major depressive disorder is estimated to occur in 10%-25% of people with cancer, and it has been inconsistently linked to increased mortality...
  22. doi request reprint Cetuximab monotherapy in patients with advanced non-small cell lung cancer after prior epidermal growth factor receptor tyrosine kinase inhibitor therapy
    Joel W Neal
    Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Thorac Oncol 5:1855-8. 2010
    ..Cetuximab is a monoclonal antibody against the EGFR receptor with antitumor activity in NSCLC. This study evaluated the efficacy of cetuximab monotherapy after prior treatment with an oral EGFR tyrosine kinase inhibitor (TKI)...
  23. doi request reprint Early integration of palliative care services with standard oncology care for patients with advanced cancer
    Joseph A Greer
    Assistant Professor of Psychology, Harvard Medical School, and Assistant in Psychology, Department of Psychiatry, Massachusetts General Hospital, Boston, MA
    CA Cancer J Clin 63:349-63. 2013
    ....
  24. doi request reprint Early palliative care and metastatic non-small cell lung cancer: potential mechanisms of prolonged survival
    Kelly E Irwin
    Massachusetts General Hospital Cancer Center, Boston, MA, USA
    Chron Respir Dis 10:35-47. 2013
    ..This review summarizes the literature on potential survival benefits of palliative care and presents a model of how early integrated palliative care could potentially influence survival in patients with advanced cancer...
  25. doi request reprint Randomized controlled trial of a video decision support tool for cardiopulmonary resuscitation decision making in advanced cancer
    Angelo E Volandes
    Massachusetts General Hospital, General Medicine Unit, 50 Staniford St, 9th Floor, Boston, MA 02114, USA
    J Clin Oncol 31:380-6. 2013
    ..Decision making regarding cardiopulmonary resuscitation (CPR) is challenging. This study examined the effect of a video decision support tool on CPR preferences among patients with advanced cancer...
  26. ncbi request reprint Behavioral and psychological predictors of chemotherapy adherence in patients with advanced non-small cell lung cancer
    Joseph A Greer
    Massachusetts General Hospital and Harvard Medical School, MA, USA
    J Psychosom Res 65:549-52. 2008
    ..The goal of this study was to explore the frequency and clinical predictors of infusion dose delays and reductions in this patient population...
  27. doi request reprint A phase II study of oxaliplatin, pemetrexed, and bevacizumab in previously treated advanced non-small cell lung cancer
    Rebecca Suk Heist
    Division of Hematology Oncology, Massachusetts General Hospital Cancer Center, Boston, Massachusetts, USA
    J Thorac Oncol 3:1153-8. 2008
    ..We investigated the activity and tolerability of the combination of oxaliplatin, pemetrexed, and bevacizumab in patients with previously treated advanced NSCLC...
  28. doi request reprint Parsing depression from fatigue in patients with cancer using the fatigue symptom inventory
    Lara Traeger
    The Center for Psychiatric Oncology and Behavioral Sciences, Massachusetts General Hospital, Boston, Massachusetts, USA
    J Pain Symptom Manage 42:52-9. 2011
    ..A central aim in the management of cancer-related fatigue (CRF) is to identify treatable causes, such as depression. However, CRF and depression symptoms overlap and frequently co-occur, complicating diagnostic assessment...
  29. pmc Anxiety disorders in long-term survivors of adult cancers
    Joseph A Greer
    Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA
    Psychosomatics 52:417-23. 2011
    ..Using data from the National Comorbidity Survey Replication (NCS-R), we compared rates of anxiety disorders between long-term cancer survivors and individuals without a history of cancer...
  30. doi request reprint Evidence-based treatment of anxiety in patients with cancer
    Lara Traeger
    Massachusetts General Hospital Cancer Center, Boston, MA, USA
    J Clin Oncol 30:1197-205. 2012
    ..The evidence-based literature supports the use of psychosocial and psychopharmacologic treatments to prevent or alleviate anxiety symptoms...
  31. ncbi request reprint Predicting life expectancy in patients with metastatic cancer receiving palliative radiotherapy: the TEACHH model
    Monica S Krishnan
    Harvard Radiation Oncology Program, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts
    Cancer 120:134-41. 2014
    ..The purpose of the current study was to develop a LE prediction model among patients receiving palliative radiotherapy (RT) that identifies those patients with short (< 3 months) and long (> 1 year) LEs...
  32. pmc Augmenting communication and decision making in the intensive care unit with a cardiopulmonary resuscitation video decision support tool: a temporal intervention study
    Jessica B McCannon
    Harvard Medical School, Boston, Massachusetts, USA
    J Palliat Med 15:1382-7. 2012
    ....
  33. pmc Tumor epidermal growth factor receptor genotype and depression in stage IV non-small cell lung cancer
    William F Pirl
    M P H, Massachusetts General Hospital Cancer Center, Yawkey 9A, 55 Fruit Street, Boston, Massachusetts 02114 USA
    Oncologist 16:1299-306. 2011
    ..We examined differences in depression severity and rates of positive screens for major depressive disorder among newly diagnosed patients with stage IV NSCLC and known epidermal growth factor receptor (EGFR) genotype...
  34. doi request reprint Phase 1-2a multicenter dose-ranging study of canfosfamide in combination with carboplatin and paclitaxel as first-line therapy for patients with advanced non-small cell lung cancer
    Lecia V Sequist
    Massachusetts General Hospital Cancer Center, Boston, Massachusetts 02114, USA
    J Thorac Oncol 4:1389-96. 2009
    ..We aimed to evaluate the safety and efficacy of canfosfamide in combination with carboplatin and paclitaxel as first-line therapy in patients with locally advanced or metastatic non-small cell lung cancer...
  35. ncbi request reprint Does palliative care improve outcomes for patients with incurable illness? A review of the evidence
    Areej El-Jawahri
    Bulfinch Medical Group, Massachusetts General Hospital, 15 Parkman Street, Wang Care Center, 5th Floor, Suite 535, Boston, MA 02114, USA
    J Support Oncol 9:87-94. 2011
    ..We conclude the review by discussing the major obstacles and future directions in evaluating and implementing standardized palliative care interventions...
  36. pmc Use of video to facilitate end-of-life discussions with patients with cancer: a randomized controlled trial
    Areej El-Jawahri
    Departments of Medicine, Neurology and Cancer Center, and Oncology, Massachusetts General Hospital, 50 Staniford St, 9th Floor, Boston, MA 02114, USA
    J Clin Oncol 28:305-10. 2010
    ..To determine whether the use of a goals-of-care video to supplement a verbal description can improve end-of-life decision making for patients with cancer...
  37. ncbi request reprint Using the differential from complete blood counts as a biomarker of fatigue in advanced non-small-cell lung cancer: an exploratory analysis
    Johanna S Paddison
    Division of Psychiatry and Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Palliat Support Care 7:213-7. 2009
    ..Our exploratory investigation considered whether variations in routinely available hematological parameters relate to the severity of fatigue reports...
  38. ncbi request reprint Documentation of oral versus intravenous chemotherapy plans in patients with metastatic non-small-cell lung cancer
    Joseph A Greer
    Massachusetts General Hospital Cancer Center, Boston, MA
    J Oncol Pract 10:e103-6. 2014
    ....
  39. doi request reprint Phase II multicenter trial of voreloxin as second-line therapy in chemotherapy-sensitive or refractory small cell lung cancer
    Lee M Krug
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, New York, USA
    J Thorac Oncol 6:384-6. 2011
    ....
  40. pmc Major depressive disorder in long-term cancer survivors: analysis of the National Comorbidity Survey Replication
    William F Pirl
    Department of Biostatistics, Massachusetts General Hospital, Yawkey 9A, 55 Fruit St, Boston, MA 02114, USA
    J Clin Oncol 27:4130-4. 2009
    ....
  41. ncbi request reprint Screening for psychosocial distress: a national survey of oncologists
    William F Pirl
    Department of Psychiatry, Massachusetts General Hospital Cancer Center, Boston, Massachusetts 02114, USA
    J Support Oncol 5:499-504. 2007
    ..Future efforts should focus on the dissemination and validation of the NCCN guidelines...
  42. pmc Management of psychosocial distress by oncologists
    Anna C Muriel
    Department of Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    Psychiatr Serv 60:1132-4. 2009
    ..The goal of this study was to survey oncologists about their management of psychosocial distress, referencing the National Comprehensive Cancer Network guidelines...
  43. pmc Predictors of newly diagnosed cancer patients' understanding of the goals of their care at initiation of chemotherapy
    Inga T Lennes
    Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA
    Cancer 119:691-9. 2013
    ..In this study, the authors sought to determine whether attributes of patients and initial patient-physician encounters were associated with patients' understanding of their GOC...
  44. pmc Delivering high-quality and affordable care throughout the cancer care continuum
    Ya Chen Tina Shih
    Ya Chen Tina Shih, University of Chicago, Chicago IL Patricia A Ganz, Denise Aberle, and Jim C Hu, University of California at Los Angeles, Los Angeles, CA Amy Abernethy, Duke University, Durham, NC Justin Bekelman, University of Pennsylvania, Philadelphia, PA Otis Brawley, American Cancer Society, Atlanta, GA James S Goodwin, University of Texas, Galveston, TX Deborah Schrag, Dana Farber Cancer Institute and Jennifer S Temel and Lowell Schnipper, Harvard Medical School, Boston, MA
    J Clin Oncol 31:4151-7. 2013
    ..This article is our summary of presentations at the workshop that highlighted the overuse and underuse of screening, treatments, and technologies throughout the cancer care continuum in oncology practice in the United States. ..
  45. pmc The diverse landscape of palliative care clinics
    Alexander K Smith
    Division of Geriatrics, Department of Medicine, University of California, San Francisco, California, USA
    J Palliat Med 16:661-8. 2013
    ..Many health care organizations are interested in instituting a palliative care clinic. However, there are insufficient published data regarding existing practices to inform the development of new programs...
  46. ncbi request reprint Predicting life expectancy in patients with advanced incurable cancer: a review
    Monica Krishnan
    Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    J Support Oncol 11:68-74. 2013
    ..This review examines tools utilized to predict life expectancy for patients with advanced, incurable cancer...
  47. ncbi request reprint A phase II study of gefitinib in patients with advanced thyroid cancer
    Nathan A Pennell
    Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Thyroid 18:317-23. 2008
    ..To determine the efficacy of gefitinib in patients with advanced thyroid cancer...
  48. ncbi request reprint Does initial staging or tumor histology better identify asymptomatic brain metastases in patients with non-small cell lung cancer?
    Ann A Shi
    Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Thorac Oncol 1:205-10. 2006
    ....
  49. ncbi request reprint Phase II clinical trial of chemotherapy-naive patients > or = 70 years of age treated with erlotinib for advanced non-small-cell lung cancer
    David M Jackman
    Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 25:760-6. 2007
    ..The secondary end points include radiographic response rate, time to progression (TTP), toxicity, and symptom improvement...
  50. pmc Racial differences in predictors of intensive end-of-life care in patients with advanced cancer
    Elizabeth Trice Loggers
    Department of MedicalOncology, Center for Psycho Oncology and Palliative Care Research, Dana Farber Cancer Institute Boston, MA 02114, USA
    J Clin Oncol 27:5559-64. 2009
    ..Black patients are more likely than white patients to receive life-prolonging care near death. This study examined predictors of intensive end-of-life (EOL) care for black and white advanced cancer patients...

Research Grants1

  1. Exercise in Patients with Advanced NSCLC: A Pilot Study
    Jennifer Temel; Fiscal Year: 2005
    ..abstract_text> ..