Research Topics
| Jennifer S TemelSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
Research Grants
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Detail Information
Publications
Complexities of quality of life analysis in non-small cell lung cancerJennifer Temel
Harvard Medical School, Boston, Massachusetts, USA
J Support Oncol 5:30-1. 2007- Phase II study: integrated palliative care in newly diagnosed advanced non-small-cell lung cancer patientsJennifer S Temel
Massachusetts General Hospital, Boston, MA 02114, USA
J Clin Oncol 25:2377-82. 2007..To assess the feasibility of early palliative care in the ambulatory setting in patients with newly diagnosed advanced non-small-cell lung cancer (NSCLC)... 
Electronic prompt to improve outpatient code status documentation for patients with advanced lung cancerJennifer S Temel
Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA
J Clin Oncol 31:710-5. 2013....- Can weight loss at presentation predict patient outcome in lung cancer?Jennifer Temel
Massachusetts General Hospital, MA, USA
Nat Clin Pract Oncol 1:68-9. 2004 
A structured exercise program for patients with advanced non-small cell lung cancerJennifer S Temel
Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Thorac Oncol 4:595-601. 2009..In this study, we examined the feasibility of a hospital-based exercise program for patients with advanced non-small cell lung cancer...- Early palliative care for patients with metastatic non-small-cell lung cancerJennifer S Temel
Massachusetts General Hospital, Boston, MA 02114, USA
N Engl J Med 363:733-42. 2010..We examined the effect of introducing palliative care early after diagnosis on patient-reported outcomes and end-of-life care among ambulatory patients with newly diagnosed disease... - Aggressiveness of care in a prospective cohort of patients with advanced NSCLCJennifer S Temel
Department of Hematology Oncology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Cancer 113:826-33. 2008..Optimal end of life care of patients with terminal cancer is poorly understood. In this study, the aggressiveness of care is described in a cohort of patients with newly diagnosed advanced nonsmall-cell lung cancer (NSCLC)... - Longitudinal perceptions of prognosis and goals of therapy in patients with metastatic non-small-cell lung cancer: results of a randomized study of early palliative careJennifer S Temel
Massachusetts GeneralHospital Cancer Center, 55 Fruit Street, Massachusetts General Hospital, Boston, MA 02114, USA
J Clin Oncol 29:2319-26. 2011..The aims of this study were to explore perceptions of prognosis and goals of therapy in patients with metastatic non-small-cell lung cancer (NSCLC) and to examine the effect of early palliative care on these views over time... - Code status documentation in the outpatient electronic medical records of patients with metastatic cancerJennifer S Temel
Massachusetts General Hospital Cancer Center, 55 Fruit Street, Yawkey 7B, Boston, MA 02114, USA
J Gen Intern Med 25:150-3. 2010..However, little is known about clinical practices in outpatient oncology settings related to discussing end-of-life care and documenting code status preferences in ambulatory medical records... - Feasibility and validity of a one-item fatigue screen in a thoracic oncology clinicJennifer S Temel
Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Thorac Oncol 1:454-9. 2006..Despite its high prevalence, it is often unrecognized and undetected. This study assessed the feasibility and validity of a one-item fatigue scale (OIFS) in an outpatient oncology clinic... - Comprehensive symptom management in patients with advanced-stage non-small-cell lung cancerJennifer S Temel
Department of Medicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
Clin Lung Cancer 7:241-9. 2006..Therefore, comprehensive care of patients with advanced-stage NSCLC must include therapies targeted at these difficult and distressing symptoms... - Depression and survival in metastatic non-small-cell lung cancer: effects of early palliative careWilliam F Pirl
Massachusetts General Hospital Cancer Center, Center for Psychiatric Oncology and Behavioral Sciences, Yawkey 9A, 55 Fruit St, Boston, MA 02114, USA
J Clin Oncol 30:1310-5. 2012..In a secondary analysis, we explored the hypothesis that the survival benefit resulted from improving depression... - Effect of early palliative care on chemotherapy use and end-of-life care in patients with metastatic non-small-cell lung cancerJoseph A Greer
Massachusetts General Hospital Cancer Center, Yawkey Building, Suite 9A, 55 Fruit St, Boston, MA 02114, USA
J Clin Oncol 30:394-400. 2012..We sought to investigate whether early palliative care also affects the frequency and timing of chemotherapy use and hospice care for these patients... - Phase I/II study of AT-101 with topotecan in relapsed and refractory small cell lung cancerRebecca Suk Heist
Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Thorac Oncol 5:1637-43. 2010..AT-101 is an oral, pan Bcl-2 family protein inhibitor that has demonstrated activity in small cell lung cancer (SCLC) models. A phase I/II study was conducted combining AT-101 with topotecan in relapsed and refractory SCLC... - A phase I study of erlotinib and hydroxychloroquine in advanced non-small-cell lung cancerSarah B Goldberg
Massachusetts General Hospital Cancer Center, Boston, MA, USA
J Thorac Oncol 7:1602-8. 2012..This investigator-initiated study explores the safety, maximum tolerated dose, clinical response, and pharmacokinetics of hydroxychloroquine (HCQ) with and without erlotinib in patients with advanced non-small-cell lung cancer... - Early palliative care in advanced lung cancer: a qualitative studyJaclyn Yoong
Massachusetts General Hospital, Boston, MA 02114, USA
JAMA Intern Med 173:283-90. 2013..During critical clinical time points, PC and oncologic care visits have distinct features that suggest a key role for PC involvement and enable oncologists to focus on cancer treatment and managing medical complications... - Cetuximab monotherapy in patients with advanced non-small cell lung cancer after prior epidermal growth factor receptor tyrosine kinase inhibitor therapyJoel W Neal
Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Thorac Oncol 5:1855-8. 2010..Cetuximab is a monoclonal antibody against the EGFR receptor with antitumor activity in NSCLC. This study evaluated the efficacy of cetuximab monotherapy after prior treatment with an oral EGFR tyrosine kinase inhibitor (TKI)... - Depression after diagnosis of advanced non-small cell lung cancer and survival: a pilot studyWilliam F Pirl
Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA
Psychosomatics 49:218-24. 2008..Major depressive disorder is estimated to occur in 10%-25% of people with cancer, and it has been inconsistently linked to increased mortality... - Randomized controlled trial of a video decision support tool for cardiopulmonary resuscitation decision making in advanced cancerAngelo E Volandes
Massachusetts General Hospital, General Medicine Unit, 50 Staniford St, 9th Floor, Boston, MA 02114, USA
J Clin Oncol 31:380-6. 2013..Decision making regarding cardiopulmonary resuscitation (CPR) is challenging. This study examined the effect of a video decision support tool on CPR preferences among patients with advanced cancer... - Behavioral and psychological predictors of chemotherapy adherence in patients with advanced non-small cell lung cancerJoseph A Greer
Massachusetts General Hospital and Harvard Medical School, MA, USA
J Psychosom Res 65:549-52. 2008..The goal of this study was to explore the frequency and clinical predictors of infusion dose delays and reductions in this patient population... - Parsing depression from fatigue in patients with cancer using the fatigue symptom inventoryLara Traeger
The Center for Psychiatric Oncology and Behavioral Sciences, Massachusetts General Hospital, Boston, Massachusetts, USA
J Pain Symptom Manage 42:52-9. 2011..A central aim in the management of cancer-related fatigue (CRF) is to identify treatable causes, such as depression. However, CRF and depression symptoms overlap and frequently co-occur, complicating diagnostic assessment... - Anxiety disorders in long-term survivors of adult cancersJoseph A Greer
Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA
Psychosomatics 52:417-23. 2011..Using data from the National Comorbidity Survey Replication (NCS-R), we compared rates of anxiety disorders between long-term cancer survivors and individuals without a history of cancer... - A phase II study of oxaliplatin, pemetrexed, and bevacizumab in previously treated advanced non-small cell lung cancerRebecca Suk Heist
Division of Hematology Oncology, Massachusetts General Hospital Cancer Center, Boston, Massachusetts, USA
J Thorac Oncol 3:1153-8. 2008..We investigated the activity and tolerability of the combination of oxaliplatin, pemetrexed, and bevacizumab in patients with previously treated advanced NSCLC... - A pilot randomized controlled trial of brief cognitive-behavioral therapy for anxiety in patients with terminal cancerJoseph A Greer
Center for Psychiatric Oncology and Behavioral Sciences, Massachusetts General Hospital Cancer Center, Yawkey Building, Suite 10B, 55 Fruit Street, Boston, Massachusetts 02114, USA
Oncologist 17:1337-45. 2012..In this pilot randomized controlled trial (clinicaltrials.gov identifier NCT00706290), we examined the feasibility and potential efficacy of brief CBT to reduce anxiety in patients with terminal cancer... - Evidence-based treatment of anxiety in patients with cancerLara Traeger
Massachusetts General Hospital Cancer Center, Boston, MA, USA
J Clin Oncol 30:1197-205. 2012..Treatment planning should incorporate contributing factors to anxiety and patient preferences for psychiatric care... - Tumor epidermal growth factor receptor genotype and depression in stage IV non-small cell lung cancerWilliam F Pirl
M P H, Massachusetts General Hospital Cancer Center, Yawkey 9A, 55 Fruit Street, Boston, Massachusetts 02114 USA
Oncologist 16:1299-306. 2011..We examined differences in depression severity and rates of positive screens for major depressive disorder among newly diagnosed patients with stage IV NSCLC and known epidermal growth factor receptor (EGFR) genotype... - Does palliative care improve outcomes for patients with incurable illness? A review of the evidenceAreej El-Jawahri
Bulfinch Medical Group, Massachusetts General Hospital, 15 Parkman Street, Wang Care Center, 5th Floor, Suite 535, Boston, MA 02114, USA
J Support Oncol 9:87-94. 2011..We conclude the review by discussing the major obstacles and future directions in evaluating and implementing standardized palliative care interventions... - Use of video to facilitate end-of-life discussions with patients with cancer: a randomized controlled trialAreej El-Jawahri
Departments of Medicine, Neurology and Cancer Center, and Oncology, Massachusetts General Hospital, 50 Staniford St, 9th Floor, Boston, MA 02114, USA
J Clin Oncol 28:305-10. 2010..To determine whether the use of a goals-of-care video to supplement a verbal description can improve end-of-life decision making for patients with cancer... - Using the differential from complete blood counts as a biomarker of fatigue in advanced non-small-cell lung cancer: an exploratory analysisJohanna S Paddison
Division of Psychiatry and Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Palliat Support Care 7:213-7. 2009..Our exploratory investigation considered whether variations in routinely available hematological parameters relate to the severity of fatigue reports... - Phase 1-2a multicenter dose-ranging study of canfosfamide in combination with carboplatin and paclitaxel as first-line therapy for patients with advanced non-small cell lung cancerLecia V Sequist
Massachusetts General Hospital Cancer Center, Boston, Massachusetts 02114, USA
J Thorac Oncol 4:1389-96. 2009..We aimed to evaluate the safety and efficacy of canfosfamide in combination with carboplatin and paclitaxel as first-line therapy in patients with locally advanced or metastatic non-small cell lung cancer... - Major depressive disorder in long-term cancer survivors: analysis of the National Comorbidity Survey ReplicationWilliam F Pirl
Department of Biostatistics, Massachusetts General Hospital, Yawkey 9A, 55 Fruit St, Boston, MA 02114, USA
J Clin Oncol 27:4130-4. 2009.... - Phase II multicenter trial of voreloxin as second-line therapy in chemotherapy-sensitive or refractory small cell lung cancerLee M Krug
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, New York, USA
J Thorac Oncol 6:384-6. 2011.... - Screening for psychosocial distress: a national survey of oncologistsWilliam F Pirl
Department of Psychiatry, Massachusetts General Hospital Cancer Center, Boston, Massachusetts 02114, USA
J Support Oncol 5:499-504. 2007..Future efforts should focus on the dissemination and validation of the NCCN guidelines... - Management of psychosocial distress by oncologistsAnna C Muriel
Department of Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
Psychiatr Serv 60:1132-4. 2009..The goal of this study was to survey oncologists about their management of psychosocial distress, referencing the National Comprehensive Cancer Network guidelines... - Predictors of newly diagnosed cancer patients' understanding of the goals of their care at initiation of chemotherapyInga T Lennes
Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA
Cancer 119:691-9. 2013..In this study, the authors sought to determine whether attributes of patients and initial patient-physician encounters were associated with patients' understanding of their GOC... - Early palliative care and metastatic non-small cell lung cancer: potential mechanisms of prolonged survivalKelly E Irwin
Massachusetts General Hospital Cancer Center, Boston, MA, USA
Chron Respir Dis 10:35-47. 2013..This review summarizes the literature on potential survival benefits of palliative care and presents a model of how early integrated palliative care could potentially influence survival in patients with advanced cancer... - Augmenting communication and decision making in the intensive care unit with a cardiopulmonary resuscitation video decision support tool: a temporal intervention studyJessica B McCannon
Harvard Medical School, Boston, Massachusetts, USA
J Palliat Med 15:1382-7. 2012.... - A phase II study of gefitinib in patients with advanced thyroid cancerNathan A Pennell
Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Thyroid 18:317-23. 2008..To determine the efficacy of gefitinib in patients with advanced thyroid cancer... - Does initial staging or tumor histology better identify asymptomatic brain metastases in patients with non-small cell lung cancer?Ann A Shi
Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Thorac Oncol 1:205-10. 2006.... - Phase II clinical trial of chemotherapy-naive patients > or = 70 years of age treated with erlotinib for advanced non-small-cell lung cancerDavid M Jackman
Dana Farber Cancer Institute, Boston, MA 02115, USA
J Clin Oncol 25:760-6. 2007..The secondary end points include radiographic response rate, time to progression (TTP), toxicity, and symptom improvement... - Racial differences in predictors of intensive end-of-life care in patients with advanced cancerElizabeth Trice Loggers
Department of MedicalOncology, Center for Psycho Oncology and Palliative Care Research, Dana Farber Cancer Institute Boston, MA 02114, USA
J Clin Oncol 27:5559-64. 2009..Black patients are more likely than white patients to receive life-prolonging care near death. This study examined predictors of intensive end-of-life (EOL) care for black and white advanced cancer patients...
Research Grants
- Exercise in Patients with Advanced NSCLC: A Pilot StudyJennifer Temel; Fiscal Year: 2005..abstract_text> ..