J A Talcott

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi request reprint Patient-reported long-term outcomes after conventional and high-dose combined proton and photon radiation for early prostate cancer
    James A Talcott
    Center for Outcomes Research, MGH Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA
    JAMA 303:1046-53. 2010
  2. pmc Measuring perceived effects of drinking an extract of basidiomycetes Agaricus blazei Murill: a survey of Japanese consumers with cancer
    James A Talcott
    Center for Outcomes Research, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA, USA
    BMC Complement Altern Med 7:32. 2007
  3. ncbi request reprint Hidden barriers between knowledge and behavior: the North Carolina prostate cancer screening and treatment experience
    James A Talcott
    Center for Outcomes Research, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts 02114, USA
    Cancer 109:1599-606. 2007
  4. ncbi request reprint Bringing prostate cancer quality of life research back to the bedside: translating numbers into a format that patients can understand
    James A Talcott
    Center for Outcomes Research, Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, Boston 02114 2696, USA
    J Urol 176:1558-63; discussion 1563-4. 2006
  5. ncbi request reprint Out-patient management of febrile neutropenia
    J A Talcott
    Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Int J Antimicrob Agents 16:169-71. 2000
  6. ncbi request reprint Quality of life in prostate cancer
    James A Talcott
    Massachusetts General Hospital, Center for Outcomes Research, Massachusetts General Cancer Centre, 75 Blossom St, Suite 230, Boston, MA 02114 2696, USA
    Eur J Cancer 41:922-31. 2005
  7. ncbi request reprint Time course and predictors of symptoms after primary prostate cancer therapy
    James A Talcott
    Center for Outcomes Research, MGH Cancer Center, Massachusetts General Hospital, Boston, 02114 2696, USA
    J Clin Oncol 21:3979-86. 2003
  8. ncbi request reprint Complications after treatment with external-beam irradiation in early-stage prostate cancer patients: a prospective multiinstitutional outcomes study
    C J Beard
    Joint Center for Radiation Therapy, Boston, MA 02115, USA
    J Clin Oncol 15:223-9. 1997
  9. ncbi request reprint Patients' perceptions of quality of life after treatment for early prostate cancer
    Jack A Clark
    Department of Health Services, Boston University School of Public Health, Boston, MA 02118, USA
    J Clin Oncol 21:3777-84. 2003
  10. ncbi request reprint Patient-reported symptoms after primary therapy for early prostate cancer: results of a prospective cohort study
    J A Talcott
    Dana Farber Cancer Institute, Brigham and Women s Hospital, Boston, MA, USA
    J Clin Oncol 16:275-83. 1998

Research Grants

  1. Outcomes Research and Training in Oncology
    James Talcott; Fiscal Year: 2005

Detail Information

Publications40

  1. doi request reprint Patient-reported long-term outcomes after conventional and high-dose combined proton and photon radiation for early prostate cancer
    James A Talcott
    Center for Outcomes Research, MGH Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA
    JAMA 303:1046-53. 2010
    ..Increased radiation doses improve prostate cancer control but also increase toxicity to adjacent normal tissue. Proton radiation may attenuate adverse effects...
  2. pmc Measuring perceived effects of drinking an extract of basidiomycetes Agaricus blazei Murill: a survey of Japanese consumers with cancer
    James A Talcott
    Center for Outcomes Research, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA, USA
    BMC Complement Altern Med 7:32. 2007
    ..To survey cancer patients who consume an extract of the Basidiomycetes Agaricus blazei Murill mushroom (Sen-Sei-Ro) to measure their self-assessment of its effects and to develop an instrument for use in future randomized trials...
  3. ncbi request reprint Hidden barriers between knowledge and behavior: the North Carolina prostate cancer screening and treatment experience
    James A Talcott
    Center for Outcomes Research, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts 02114, USA
    Cancer 109:1599-606. 2007
    ..To identify patient factors that might account for some of this disparity, men within 6 months of diagnosis were surveyed about health attitudes and behavior...
  4. ncbi request reprint Bringing prostate cancer quality of life research back to the bedside: translating numbers into a format that patients can understand
    James A Talcott
    Center for Outcomes Research, Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, Boston 02114 2696, USA
    J Urol 176:1558-63; discussion 1563-4. 2006
    ..We present an approach that preserves the methodological strengths of validated multi-item measures but provides more accessible information for clinical use...
  5. ncbi request reprint Out-patient management of febrile neutropenia
    J A Talcott
    Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Int J Antimicrob Agents 16:169-71. 2000
    ..The data identifying low risk patients, treatment strategies for low risk patients, and additional information required before recommending out-patient management of fever and neutropenia widely are described...
  6. ncbi request reprint Quality of life in prostate cancer
    James A Talcott
    Massachusetts General Hospital, Center for Outcomes Research, Massachusetts General Cancer Centre, 75 Blossom St, Suite 230, Boston, MA 02114 2696, USA
    Eur J Cancer 41:922-31. 2005
    ....
  7. ncbi request reprint Time course and predictors of symptoms after primary prostate cancer therapy
    James A Talcott
    Center for Outcomes Research, MGH Cancer Center, Massachusetts General Hospital, Boston, 02114 2696, USA
    J Clin Oncol 21:3979-86. 2003
    ..We characterized the time course of treatment complications while adjusting for potentially confounding pretreatment factors hindering other observational studies...
  8. ncbi request reprint Complications after treatment with external-beam irradiation in early-stage prostate cancer patients: a prospective multiinstitutional outcomes study
    C J Beard
    Joint Center for Radiation Therapy, Boston, MA 02115, USA
    J Clin Oncol 15:223-9. 1997
    ..To use data from a prospective quality-of-life study to assess differences in disease-specific and general health-related quality-of-life changes after treatment with different external-beam irradiation techniques for prostate cancer...
  9. ncbi request reprint Patients' perceptions of quality of life after treatment for early prostate cancer
    Jack A Clark
    Department of Health Services, Boston University School of Public Health, Boston, MA 02118, USA
    J Clin Oncol 21:3777-84. 2003
    ..Treatment for early prostate cancer produces problematic physical side effects, but prior studies have found little influence on patients' perceived health status. We examined psychosocial outcomes of treatment for early prostate cancer...
  10. ncbi request reprint Patient-reported symptoms after primary therapy for early prostate cancer: results of a prospective cohort study
    J A Talcott
    Dana Farber Cancer Institute, Brigham and Women s Hospital, Boston, MA, USA
    J Clin Oncol 16:275-83. 1998
    ..To assess complications of therapy for early (nonmetastatic) prostate cancer...
  11. ncbi request reprint United States radiation oncologists' and urologists' opinions about screening and treatment of prostate cancer vary by region
    Mary McNaughton Collins
    Medical Practices Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Urology 60:628-33. 2002
    ..To examine whether physicians' views on prostate cancer screening and treatment vary by geographic region in the United States...
  12. ncbi request reprint Androgen deprivation-mediated cytoreduction before interstitial brachytherapy for prostate cancer does not abrogate the elevated risk of urinary morbidity associated with larger initial prostate volume
    Joshua H Petit
    Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Brachytherapy 6:267-71. 2007
    ..We examined whether prostate volume reduction after a short course of androgen deprivation (AD) lowered the risks of acute and chronic urinary morbidity related to radioactive seed implantation for low-risk prostate cancer...
  13. ncbi request reprint Organ conservation in invasive bladder cancer by transurethral resection, chemotherapy and radiation: results of a urodynamic and quality of life study on long-term survivors
    Anthony L Zietman
    Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, 100 Blossom Street, Cox 302, Boston, MA 02114, USA
    J Urol 170:1772-6. 2003
    ..Concern exists about the function of the retained bladder after such therapy...
  14. ncbi request reprint Patient-reported acute gastrointestinal toxicity in men receiving 3-dimensional conformal radiation therapy for prostate cancer with or without neoadjuvant androgen suppression therapy
    Henry K Tsai
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, MA 02115, USA
    Urol Oncol 23:230-7. 2005
    ..To investigate the impact of 2 months of neoadjuvant and 2 months of concurrent hormonal therapy on the acute gastrointestinal (GI) toxicities associated with 3-dimensional conformal radiation therapy (3D-CRT) for prostate adenocarcinoma...
  15. ncbi request reprint New era in prostate-cancer care: what we know and what we don't
    James A Talcott
    Center for Outcomes Research, MGH Cancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Lancet Oncol 4:204-5. 2003
  16. doi request reprint Rectal dose-volume histogram parameters are associated with long-term patient-reported gastrointestinal quality of life after conventional and high-dose radiation for prostate cancer: a subgroup analysis of a randomized trial
    Paul L Nguyen
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 78:1081-5. 2010
    ..2 GyE) or high-dose (79.2 GyE) radiation for prostate cancer...
  17. ncbi request reprint Treatment 'mismatch' in early prostate cancer: do treatment choices take patient quality of life into account?
    Ronald C Chen
    Center for Outcomes Research, MGH Cancer Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Cancer 112:61-8. 2008
    ..Using patient-reported baseline dysfunction from a prospective cohort study, we determined the proportion of patients receiving relatively contraindicated ('mismatched') treatments...
  18. ncbi request reprint Assessing a prostate cancer brachytherapy technique using early patient-reported symptoms: a potential early indicator for technology assessment?
    Pearl H Seo
    Massachusetts General Hospital, Boston, MA 02114 2693, USA
    Clin Prostate Cancer 3:38-42. 2004
    ..However, these results suggest that measuring early symptoms may indicate whether an altered brachytherapy treatment technique has intended favorable consequences, potentially accelerating technology assessment...
  19. ncbi request reprint Long-term treatment related complications of brachytherapy for early prostate cancer: a survey of patients previously treated
    J A Talcott
    Massachusetts General Hospital, Harvard Medical School and Boston University School of Public Health, Boston, Massachusetts, USA
    J Urol 166:494-9. 2001
    ..The morbidity of patients receiving more recent brachytherapy may be less...
  20. ncbi request reprint Sexuality and cancer: conversation comfort zone
    R T Penson
    The Kenneth B Schwartz Center at Massachusetts General Hospital, Hematology Oncology Department, Boston, Massachusettts 02114 2617, USA
    Oncologist 5:336-44. 2000
    ..A sensitive and informed approach to discussing sexuality can provide effective support. The elements of successful dialogue are presented in the PLISSIT model...
  21. ncbi request reprint Assessing suspected spinal cord compression: a multidisciplinary outcomes analysis of 342 episodes
    J A Talcott
    Dana Farber Cancer Institute, Boston, MA 02115, USA
    Support Care Cancer 7:31-8. 1999
    ....
  22. ncbi request reprint Measuring patients' perceptions of the outcomes of treatment for early prostate cancer
    Jack A Clark
    Health Services Department, Boston University School of Public Health, and Center for Health Quality, Outcomes, and Economic Research, Edith Nourse Rogers Memorial Veterans Hospital Bedford, Boston, Massachusetts 02118, USA
    Med Care 41:923-36. 2003
    ....
  23. doi request reprint Patient-reported acute gastrointestinal symptoms during concurrent chemoradiation treatment for rectal cancer
    Ronald C Chen
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Cancer 116:1879-86. 2010
    ..The authors undertook the current study to assess the feasibility of incorporating PRO measurement into routine clinical practice and to describe the trajectory of symptom development during treatment...
  24. doi request reprint Individualizing quality-of-life outcomes reporting: how localized prostate cancer treatments affect patients with different levels of baseline urinary, bowel, and sexual function
    Ronald C Chen
    Center for Outcomes Research, Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, Boston, MA, USA
    J Clin Oncol 27:3916-22. 2009
    ..Using levels of treatment-related dysfunction, we address these problems and present the final QOL outcomes of our prospective cohort study of patients with early prostate cancer...
  25. ncbi request reprint Confidence and uncertainty long after initial treatment for early prostate cancer: survivors' views of cancer control and the treatment decisions they made
    Jack A Clark
    Center for Health Quality, Outcomes, and Economic Research, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, USA
    J Clin Oncol 24:4457-63. 2006
    ..The many years most men diagnosed with early prostate cancer live after diagnosis allow evolving assessments of their cancer control and their treatment choices, but little is known of these outcomes or the factors that influence them...
  26. pmc Perceived family history risk and symptomatic diagnosis of prostate cancer: the North Carolina Prostate Cancer Outcomes study
    Pamela Spain
    Cecil G Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27709 2194, USA
    Cancer 113:2180-7. 2008
    ..African American (AA) men remain at significantly greater risk of PrCA diagnosis and mortality than other men. Many factors contribute to the experienced disparities...
  27. ncbi request reprint Racial differences in clinical progression among Medicare recipients after treatment for localized prostate cancer (United States)
    Jacob H Cohen
    Department of Urology, SUNY Downstate Medical School, Brooklyn, NY, USA
    Cancer Causes Control 17:803-11. 2006
    ..We investigate differences in disease-free survival among white, black, Hispanic, and Asian patients in a large, population-based database...
  28. ncbi request reprint Prostate cancer quality of life: beyond initial treatment and the patient
    James A Talcott
    J Clin Oncol 25:4155-6. 2007
  29. doi request reprint Outcomes and cost of outpatient or inpatient management of 712 patients with febrile neutropenia
    Linda S Elting
    Department of Biostatistics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd Unit 447, Houston, TX 77030, USA
    J Clin Oncol 26:606-11. 2008
    ..We retrospectively compared the outcomes and costs of outpatient and inpatient management of low-risk outpatients who presented to an emergency department with febrile neutropenia (FN)...
  30. ncbi request reprint Methodology for clinical trials involving patients with cancer who have febrile neutropenia: updated guidelines of the Immunocompromised Host Society/Multinational Association for Supportive Care in Cancer, with emphasis on outpatient studies
    Ronald Feld
    Department of Hematology and Oncology, Princess Margaret Hospital, Toronto, Ontario, Canada M5G 2M9
    Clin Infect Dis 35:1463-8. 2002
    ..Response and safety parameters should be recorded along with readmission rates. If studies use these guidelines, comparisons between studies will be simpler and will lead to further improvements in patient therapy...
  31. ncbi request reprint Rebalancing ratios and improving impressions: later thoughts from the prostate cancer prevention trial investigators
    James A Talcott
    J Clin Oncol 23:7388-90. 2005
  32. ncbi request reprint What patients should be told before agreeing to a blood test that could change their lives
    James A Talcott
    Urology 61:7-9. 2003
  33. ncbi request reprint Quality of care in prostate cancer: important to start and too important to stop here
    James A Talcott
    J Clin Oncol 21:1902-3. 2003
  34. ncbi request reprint Racial differences in mortality among Medicare recipients after treatment for localized prostate cancer
    Paul A Godley
    Division of Hematology Oncology, School of Medicine and the Center for Health Promotion and Disease Prevention, The University of North Carolina at Chapel Hill, 27599 7305, USA
    J Natl Cancer Inst 95:1702-10. 2003
    ..We investigated whether racial disparities in outcomes of clinically localized prostate cancer vary by treatment (surgery, radiation therapy, or nonaggressive treatment)...
  35. ncbi request reprint American Society of Clinical Oncology recommendations for the initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer
    D Andrew Loblaw
    Cancer Policy and Clinical Affairs, 1900 Duke St, Suite 200, Alexandria, VA 22314, USA
    J Clin Oncol 22:2927-41. 2004
    ..The focus of this document is on the use, combinations, and timing of various forms of androgen deprivation therapy (ADT) for the palliation of men with androgen-sensitive disease...
  36. ncbi request reprint Androgen deprivation as primary treatment for early prostate cancer: should we "just do something"?
    James A Talcott
    J Natl Cancer Inst 94:407-9. 2002
  37. ncbi request reprint Employment after therapy for localized prostate cancer: widening the perspective
    James A Talcott
    J Natl Cancer Inst 97:948-9. 2005
  38. ncbi request reprint Suspected spinal cord compression in cancer patients: a multidisciplinary risk assessment
    Charles Lu
    Department of Thoracic Head and Neck Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston 77030 4009, USA
    J Support Oncol 3:305-12. 2005
    ..These predictors may help clinicians to assess risk in this patient population...
  39. ncbi request reprint How could getting screened for prostate cancer hurt you?
    James A Talcott
    Urol Oncol 23:374-5. 2005
  40. ncbi request reprint Data pooling and analysis to build a preliminary item bank: an example using bowel function in prostate cancer
    David T Eton
    Northwestern University School of Medicine, Evanston, IL 60201, USA
    Eval Health Prof 28:142-59. 2005
    ..A fifth item assessing hemorrhoids was poorly correlated with other items. Our analyses supported four related components of BF: diarrhea, rectal urgency, pain, and bother/distress...

Research Grants1

  1. Outcomes Research and Training in Oncology
    James Talcott; Fiscal Year: 2005
    ..One approach to these issues is to identify differences in outcomes based on the mode of diagnosis (screening vs. investigation of symptoms). ..