Peter H Stone

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Evaluating cardiovascular pathophysiology and anatomy in atherosclerosis
    Peter H Stone
    Clinical Trials Center, Samuel A Levine Cardiac Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am Heart Hosp J 3:187-92. 2005
  2. doi request reprint Prediction of progression of coronary artery disease and clinical outcomes using vascular profiling of endothelial shear stress and arterial plaque characteristics: the PREDICTION Study
    Peter H Stone
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Circulation 126:172-81. 2012
  3. doi request reprint The anti-ischemic mechanism of action of ranolazine in stable ischemic heart disease
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 56:934-42. 2010
  4. ncbi request reprint Antianginal efficacy of ranolazine when added to treatment with amlodipine: the ERICA (Efficacy of Ranolazine in Chronic Angina) trial
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Am Coll Cardiol 48:566-75. 2006
  5. doi request reprint Ranolazine: new paradigm for management of myocardial ischemia, myocardial dysfunction, and arrhythmias
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115 6110, USA
    Cardiol Clin 26:603-14. 2008
  6. pmc Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs
    Yiannis S Chatzizisis
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Circulation 123:621-30. 2011
  7. ncbi request reprint Prediction of sites of coronary atherosclerosis progression: In vivo profiling of endothelial shear stress, lumen, and outer vessel wall characteristics to predict vascular behavior
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Opin Cardiol 18:458-70. 2003
  8. ncbi request reprint Vascular basis for the treatment of myocardial ischemia study: trial design and baseline characteristics
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Mass 02115, USA
    Am Heart J 147:875-82. 2004
  9. ncbi request reprint Effect of intensive lipid lowering, with or without antioxidant vitamins, compared with moderate lipid lowering on myocardial ischemia in patients with stable coronary artery disease: the Vascular Basis for the Treatment of Myocardial Ischemia Study
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Mass 02115, USA
    Circulation 111:1747-55. 2005
  10. ncbi request reprint ST-segment analysis in ambulatory ECG (AECG or Holter) monitoring in patients with coronary artery disease: clinical significance and analytic techniques
    Peter H Stone
    Cardiovascular Division Brigham and Women s Hospital Harvard Medical School, Boston, MA 02115, USA
    Ann Noninvasive Electrocardiol 10:263-78. 2005

Detail Information

Publications70

  1. ncbi request reprint Evaluating cardiovascular pathophysiology and anatomy in atherosclerosis
    Peter H Stone
    Clinical Trials Center, Samuel A Levine Cardiac Unit, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am Heart Hosp J 3:187-92. 2005
    ..These techniques may provide a means to identify patients at risk for adverse cardiovascular outcomes, thereby enabling physicians to potentially prevent adverse events by early initiation of lipid-lowering therapy...
  2. doi request reprint Prediction of progression of coronary artery disease and clinical outcomes using vascular profiling of endothelial shear stress and arterial plaque characteristics: the PREDICTION Study
    Peter H Stone
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Circulation 126:172-81. 2012
    ....
  3. doi request reprint The anti-ischemic mechanism of action of ranolazine in stable ischemic heart disease
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 56:934-42. 2010
    ....
  4. ncbi request reprint Antianginal efficacy of ranolazine when added to treatment with amlodipine: the ERICA (Efficacy of Ranolazine in Chronic Angina) trial
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Am Coll Cardiol 48:566-75. 2006
    ..The purpose of this study was to determine if ranolazine improves angina in stable coronary patients with persisting symptoms despite maximum recommended dose of amlodipine...
  5. doi request reprint Ranolazine: new paradigm for management of myocardial ischemia, myocardial dysfunction, and arrhythmias
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115 6110, USA
    Cardiol Clin 26:603-14. 2008
    ..This article provides an update on the available studies concerning the value of ranolazine across the spectrum of cardiovascular disease...
  6. pmc Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs
    Yiannis S Chatzizisis
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Circulation 123:621-30. 2011
    ..Our results provide new insight into the mechanisms of regional formation of plaques with thin fibrous caps...
  7. ncbi request reprint Prediction of sites of coronary atherosclerosis progression: In vivo profiling of endothelial shear stress, lumen, and outer vessel wall characteristics to predict vascular behavior
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Opin Cardiol 18:458-70. 2003
    ..Accurate identification of arterial segments at high risk for progression may permit preemptive intervention strategies to avoid adverse coronary events...
  8. ncbi request reprint Vascular basis for the treatment of myocardial ischemia study: trial design and baseline characteristics
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Mass 02115, USA
    Am Heart J 147:875-82. 2004
    ....
  9. ncbi request reprint Effect of intensive lipid lowering, with or without antioxidant vitamins, compared with moderate lipid lowering on myocardial ischemia in patients with stable coronary artery disease: the Vascular Basis for the Treatment of Myocardial Ischemia Study
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Mass 02115, USA
    Circulation 111:1747-55. 2005
    ..Lipid lowering with statins prevents adverse cardiac events. Both lipid-lowering and antioxidant therapies may favorably affect vasomotor function and thereby improve ischemia...
  10. ncbi request reprint ST-segment analysis in ambulatory ECG (AECG or Holter) monitoring in patients with coronary artery disease: clinical significance and analytic techniques
    Peter H Stone
    Cardiovascular Division Brigham and Women s Hospital Harvard Medical School, Boston, MA 02115, USA
    Ann Noninvasive Electrocardiol 10:263-78. 2005
  11. ncbi request reprint Update in cardiology
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Ann Intern Med 143:737-43. 2005
  12. ncbi request reprint Effect of endothelial shear stress on the progression of coronary artery disease, vascular remodeling, and in-stent restenosis in humans: in vivo 6-month follow-up study
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, Mass 02115, USA
    Circulation 108:438-44. 2003
    ..The endothelium controls local arterial responses by transduction of shear stress. Characterization of endothelial shear stress (ESS) may allow for prediction of progression of atherosclerosis and in-stent restenosis...
  13. ncbi request reprint Regions of low endothelial shear stress are the sites where coronary plaque progresses and vascular remodelling occurs in humans: an in vivo serial study
    Peter H Stone
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Eur Heart J 28:705-10. 2007
    ..Local haemodynamic factors are critical determinants of plaque progression, vascular remodelling, and clinical CAD manifestations...
  14. ncbi request reprint Reproducibility of coronary lumen, plaque, and vessel wall reconstruction and of endothelial shear stress measurements in vivo in humans
    Ahmet U Coskun
    Department of Mechanical, Industrial and Manufacturing Engineering, Northeastern University, Boston, Massachusetts, USA
    Catheter Cardiovasc Interv 60:67-78. 2003
    ..This methodology provides a tool to examine the effect of ESS on atherogenesis, remodeling, and restenosis; the contribution of arterial remodeling and plaque growth to changes in the lumen; and the impact of new therapies...
  15. pmc Natural history of experimental coronary atherosclerosis and vascular remodeling in relation to endothelial shear stress: a serial, in vivo intravascular ultrasound study
    Konstantinos C Koskinas
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    Circulation 121:2092-101. 2010
    ..We performed a serial study to assess the role of endothelial shear stress (ESS) and vascular remodeling in the natural history of coronary atherosclerosis...
  16. ncbi request reprint Association between thrombolysis in myocardial infarction myocardial perfusion grade, biomarkers, and clinical outcomes among patients with moderate- to high-risk acute coronary syndromes: observations from the randomized trial to evaluate the relative PR
    C Michael Gibson
    TIMI Study Group, Cardiovascular Division, Brigham and Women s Hospital, Boston, MA, USA
    Am Heart J 152:756-61. 2006
    ..A variety of imaging modalities have implicated impaired myocardial perfusion in the pathogenesis of acute coronary syndromes (ACSs)...
  17. ncbi request reprint Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior
    Yiannis S Chatzizisis
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Coll Cardiol 49:2379-93. 2007
    ....
  18. doi request reprint Attenuation of inflammation and expansive remodeling by Valsartan alone or in combination with Simvastatin in high-risk coronary atherosclerotic plaques
    Yiannis S Chatzizisis
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, United States
    Atherosclerosis 203:387-94. 2009
    ....
  19. doi request reprint Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress
    Konstantinos C Koskinas
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Arterioscler Thromb Vasc Biol 33:1494-504. 2013
    ..This study tested the hypothesis that coronary regions exposed to low endothelial shear stress (ESS) favor subsequent development of collagen-poor, thin-capped plaques...
  20. doi request reprint Prediction of the localization of high-risk coronary atherosclerotic plaques on the basis of low endothelial shear stress: an intravascular ultrasound and histopathology natural history study
    Yiannis S Chatzizisis
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    Circulation 117:993-1002. 2008
    ..Our hypothesis was that the lowest values of ESS are responsible for the development of high-risk coronary atherosclerotic plaques associated with excessive expansive remodeling...
  21. pmc Air pollution and ST-segment depression in elderly subjects
    Diane R Gold
    Channing Laboratory, Brigham and Women s Hospital, Department of Medicine, Harvard Medical School, Boston, Massachusetts 02215, USA
    Environ Health Perspect 113:883-7. 2005
    ..Carbon monoxide was not a confounder of this association. ST-segment depression, possibly representing myocardial ischemia or inflammation, is associated with increased exposure to particles whose predominant source is traffic...
  22. pmc Reduction in heart rate variability with traffic and air pollution in patients with coronary artery disease
    Antonella Zanobetti
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02215, USA
    Environ Health Perspect 118:324-30. 2010
    ..Ambient particulate pollution and traffic have been linked to myocardial infarction and cardiac death risk. Possible mechanisms include autonomic cardiac dysfunction...
  23. doi request reprint Systemic inflammation, heart rate variability and air pollution in a cohort of senior adults
    Heike Luttmann-Gibson
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02215, USA
    Occup Environ Med 67:625-30. 2010
    ..We examined the association between inflammation and autonomic dysfunction and effect modification of inflammation on the association between air pollution and heart rate variability (HRV) in elderly subjects...
  24. pmc T-wave alternans, air pollution and traffic in high-risk subjects
    Antonella Zanobetti
    Exposure, Epidemiology and Risk Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Cardiol 104:665-70. 2009
    ..6 for a 1 microg/m(3) increase in 6-hour mean BC). In conclusion, after hospitalization for coronary artery disease, being in traffic and short-term ambient or indoor BC exposure increased TWA, a marker of cardiac electrical instability...
  25. ncbi request reprint Remodeling characteristics of minimally diseased coronary arteries are consistent along the length of the artery
    Charles L Feldman
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Am J Cardiol 97:13-6. 2006
    ..Each artery was consistent in its remodeling characteristics from proximal to distal portions of the artery, and the remodeling pattern of each artery was independent within the same patient...
  26. ncbi request reprint Focused exposures to airborne traffic particles and heart rate variability in the elderly
    Sara Dubowsky Adar
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    Epidemiology 18:95-103. 2007
    ..Because these risks may be particularly great for traffic-related particles, we examined associations between particles and heart rate variability as 44 subjects participated in 4 repeated trips aboard a diesel bus...
  27. pmc Particulate air pollution as a risk factor for ST-segment depression in patients with coronary artery disease
    Kai Jen Chuang
    Exposure, Epidemiology, and Risk Program, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02215, USA
    Circulation 118:1314-20. 2008
    ..The association of particulate matter (PM) with cardiovascular morbidity and mortality is well documented. PM-induced ischemia is considered a potential mechanism linking PM to adverse cardiovascular outcomes...
  28. ncbi request reprint Short-term effects of air pollution on heart rate variability in senior adults in Steubenville, Ohio
    Heike Luttmann-Gibson
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02215, USA
    J Occup Environ Med 48:780-8. 2006
    ..We examined the association between ambient air pollution levels and heart rate variability (HRV) in a panel study of 32 subjects...
  29. doi request reprint In-vivo assessment of the natural history of coronary atherosclerosis: vascular remodeling and endothelial shear stress determine the complexity of atherosclerotic disease progression
    Michail I Papafaklis
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Opin Cardiol 25:627-38. 2010
    ..The purpose of this review is to summarize the processes underlying the heterogeneity of coronary atherosclerosis progression in relation to the local hemodynamic and arterial remodeling environment...
  30. ncbi request reprint Determination of in vivo velocity and endothelial shear stress patterns with phasic flow in human coronary arteries: a methodology to predict progression of coronary atherosclerosis
    Charles L Feldman
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Mass 02115, USA
    Am Heart J 143:931-9. 2002
    ....
  31. ncbi request reprint Comparison of effect of intensive lipid lowering with atorvastatin to less intensive lowering with lovastatin on C-reactive protein in patients with stable angina pectoris and inducible myocardial ischemia
    Scott Kinlay
    Cardiovascular Division, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Cardiol 89:1205-7. 2002
  32. doi request reprint Ischemia detected on continuous electrocardiography after acute coronary syndrome: observations from the MERLIN-TIMI 36 (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndrome-Thrombolysis In Myocardial Infarcti
    Benjamin M Scirica
    TIMI Study Group, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 53:1411-21. 2009
    ..The purpose of this study was to assess the relationship between ischemia detected on continuous electrocardiographic (cECG) recording and cardiovascular outcomes after acute coronary syndrome (ACS)...
  33. ncbi request reprint Recombinant nematode anticoagulant protein c2 in patients with non-ST-segment elevation acute coronary syndrome: the ANTHEM-TIMI-32 trial
    Robert P Giugliano
    TIMI Study Group, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 49:2398-407. 2007
    ..We sought to evaluate the safety and efficacy of recombinant nematode anticoagulant protein c2 (rNAPc2) in patients with non-ST-segment elevation acute coronary syndrome (nSTE-ACS)...
  34. ncbi request reprint Risk stratification of individual coronary lesions using local endothelial shear stress: a new paradigm for managing coronary artery disease
    Yiannis S Chatzizisis
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Curr Opin Cardiol 22:552-64. 2007
    ....
  35. doi request reprint Synergistic effect of local endothelial shear stress and systemic hypercholesterolemia on coronary atherosclerotic plaque progression and composition in pigs
    Konstantinos C Koskinas
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, United States Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States
    Int J Cardiol 169:394-401. 2013
    ....
  36. doi request reprint Timing and duration of myocardial ischemia on Holter monitoring following percutaneous coronary intervention and their association with clinical outcomes (a PROTECT-TIMI 30 Substudy Analysis)
    C Michael Gibson
    TIMI Study Group, Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Am J Cardiol 104:36-40. 2009
    ..Holter monitoring may be a useful surrogate end point in clinical trials...
  37. ncbi request reprint Predictors of mortality, coronary angiography, and revascularization in unstable angina pectoris and acute non-ST elevation myocardial infarction (the TIMI III Registry)
    Peter J Sharis
    Cardiovascular Division and Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Am J Cardiol 90:1154-6. 2002
  38. ncbi request reprint Personal coronary risk profiles modify autonomic nervous system responses to air pollution
    Jiu Chiuan Chen
    Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    J Occup Environ Med 48:1133-42. 2006
    ..We investigated whether PM2.5-mediated autonomic modulation depends on individual coronary risk profiles...
  39. doi request reprint The clinical significance of continuous ECG (ambulatory ECG or Holter) monitoring of the ST-segment to evaluate ischemia: a review
    Neil J Wimmer
    Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Prog Cardiovasc Dis 56:195-202. 2013
    ..Future research is warranted to study the effects of newer medical agents or the selected use of revascularization in those patients with persistent silent ischemia despite current medical regiments. ..
  40. doi request reprint Comparison of myocardial ischemia during intense mental stress using flight simulation in airline pilots with coronary artery disease to that produced with conventional mental and treadmill exercise stress testing
    Andrew Doorey
    Department of Medicine, Christiana Care Health Systems and Thomas Jefferson University Medical School, Philadelphia, Pennsylvania, USA
    Am J Cardiol 108:651-7. 2011
    ..In conclusion, even with equivalent hemodynamic stress, intense realistic mental stress induced by flight simulators results in significantly less myocardial ischemia than ES as measured by ST-segment depression and nuclear ischemia...
  41. ncbi request reprint A randomized trial to evaluate the relative protection against post-percutaneous coronary intervention microvascular dysfunction, ischemia, and inflammation among antiplatelet and antithrombotic agents: the PROTECT-TIMI-30 trial
    C Michael Gibson
    TIMI Study Group, Cardiovascular Division, Brigham and Women s Hospital and Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
    J Am Coll Cardiol 47:2364-73. 2006
    ....
  42. doi request reprint The role of low endothelial shear stress in the conversion of atherosclerotic lesions from stable to unstable plaque
    Konstantinos C Koskinas
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Curr Opin Cardiol 24:580-90. 2009
    ..The purpose of this review is to summarize the role of low endothelial shear stress (ESS) in the transition of early, stable plaques to high-risk atherosclerotic lesions...
  43. ncbi request reprint Current strategies for the prevention of angina in patients with stable coronary artery disease
    Ami B Bhatt
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Opin Cardiol 21:492-502. 2006
    ..The current recommended pharmacologic and invasive approaches, as well as novel therapies, are reviewed...
  44. doi request reprint Brachial artery responses to ambient pollution, temperature, and humidity in people with type 2 diabetes: a repeated-measures study
    Antonella Zanobetti
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    Environ Health Perspect 122:242-8. 2014
    ..Extreme weather and air pollution are associated with increased cardiovascular risk in people with diabetes...
  45. doi request reprint Relation of death within 90 days of non-ST-elevation acute coronary syndromes to variability in electrocardiographic morphology
    Zeeshan Syed
    Harvard MIT Division of Health Sciences and Technology, Cambridge, MA, USA
    Am J Cardiol 103:307-11. 2009
    ..In conclusion, our results suggest that increased variation in the entire heart beat morphology is associated with a considerably elevated risk of death and may provide information complementary to the analysis of heart rate...
  46. doi request reprint The effect of statins on high-risk atherosclerotic plaque associated with low endothelial shear stress
    Saeko Takahashi
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Opin Lipidol 22:358-64. 2011
    ..The purpose of this review is to summarize the relationship among low ESS, high-risk plaque and statins...
  47. ncbi request reprint Economic consequences of routine coronary angiography in low- and intermediate-risk patients with unstable angina pectoris
    Akshay S Desai
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
    Am J Cardiol 92:363-7. 2003
    ....
  48. ncbi request reprint Which patients with unstable angina or non-Q-wave myocardial infarction should have immediate cardiac catheterization? A clinical decision rule for predicting who will fail medical therapy
    Daniel H Solomon
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, 221 Longwood Avenue, Suite 341, Boston, MA 02115, USA
    J Clin Epidemiol 55:121-8. 2002
    ..Such a rule may be useful for identifying patients who should be considered for early cardiac catheterization...
  49. doi request reprint Anti-anginal and anti-ischemic effects of late sodium current inhibition
    Neil J Wimmer
    Division of Cardiovascular Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Cardiovasc Drugs Ther 27:69-77. 2013
    ....
  50. ncbi request reprint Ambient pollution and blood pressure in cardiac rehabilitation patients
    Antonella Zanobetti
    Department of Environmental Health, Exposure Epidemiology and Risk Program, Harvard School of Public Health, 401 Park Dr, Landmark Center, Suite 415, PO Box 15698, Boston, Mass 02215, USA
    Circulation 110:2184-9. 2004
    ..We investigated the associations between fine particulate pollution (PM2.5) and blood pressure during 631 repeated visits for cardiac rehabilitation in 62 Boston residents with cardiovascular disease...
  51. ncbi request reprint Triggering myocardial infarction
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, USA
    N Engl J Med 351:1716-8. 2004
  52. ncbi request reprint The effect of a telephone counseling intervention on self-rated health of cardiac patients
    Kara Zivin Bambauer
    Harvard Medical School, Boston, Massachusetts 02215, USA
    Psychosom Med 67:539-45. 2005
    ..The objective of this study was to evaluate the effectiveness of a telephone-based intervention on psychological distress among patients with cardiac illness...
  53. ncbi request reprint Prognosis in the thrombolysis in myocardial ischemia III registry according to the Braunwald unstable angina pectoris classification
    Benjamin M Scirica
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Am J Cardiol 90:821-6. 2002
    ..Given their high risk for adverse events, patients with secondary UAP should be treated aggressively...
  54. doi request reprint Implementation of a Hospital-wide Protocol for Induced Hypothermia Following Successfully Resuscitated Cardiac Arrest
    Paul M Szumita
    Department of Pharmacy, Brigham and Women s Hospital, Boston, MA, USA
    Crit Pathw Cardiol 9:216-20. 2010
    ..We describe our institutional guidelines for the initiation and management of induced hypothermia in patients successfully resuscitated from a cardiac arrest...
  55. ncbi request reprint Prinzmetal's angina detected by exercise Tc-99m tetrofosmin SPECT
    Milind Y Desai
    Division of Nuclear Cardiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    J Nucl Cardiol 9:353-4. 2002
  56. ncbi request reprint Optimizing ambulatory ECG monitoring of T-wave alternans for arrhythmia risk assessment
    Richard L Verrier
    Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Card Electrophysiol Rev 6:329-33. 2002
    ..These recent developments make possible the TWA analysis of ambulatory ECGs not only in prospective trials but also in vast stores of archival data...
  57. ncbi request reprint Update in cardiology
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Ann Intern Med 138:482-7. 2003
  58. doi request reprint New advances in cardiac computed tomography
    Prasad Guntur Ramkumar
    Applied Imaging Science Laboratory, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Curr Opin Cardiol 24:596-603. 2009
    ..This review focuses on post-64 generation CT scanner capabilities and novel clinical research applications enabled by these technologies...
  59. ncbi request reprint The Critical Care Safety Study: The incidence and nature of adverse events and serious medical errors in intensive care
    Jeffrey M Rothschild
    Divisions of General Internal Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Crit Care Med 33:1694-700. 2005
    ..We sought to study the incidence and nature of adverse events and serious errors in the critical care setting...
  60. ncbi request reprint Mental stress-induced ischemia and all-cause mortality in patients with coronary artery disease: Results from the Psychophysiological Investigations of Myocardial Ischemia study
    David S Sheps
    University of Florida College of Medicine, the Malcom Randall Veterans Affairs Medical Center, and the Medical Research Service of the Department of Veterans Affairs, Gainesville, Fla 32610 0277, USA
    Circulation 105:1780-4. 2002
    ..Ischemia during laboratory mental stress tests has been linked to significantly higher rates of adverse cardiac events. Previous studies have not been designed to detect differences in mortality rates...
  61. ncbi request reprint Air pollution: an insidious and pervasive component of cardiac risk
    Richard L Verrier
    Circulation 106:890-2. 2002
  62. ncbi request reprint From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II
    Morteza Naghavi
    The Center for Vulnerable Plaque Research, University of Texas Houston, The Texas Heart Institute, and President Bush Center for Cardiovascular Health, Memorial Hermann Hospital, Houston, USA
    Circulation 108:1772-8. 2003
    ..We encourage healthcare policy makers to promote translational research for screening and treatment of vulnerable patients...
  63. ncbi request reprint Randomized trial of a medical food for the dietary management of chronic, stable angina
    Andrew J Maxwell
    Division of Research and Development, Cooke Pharma, Inc, Belmont, California, USA
    J Am Coll Cardiol 39:37-45. 2002
    ..We determined the electrocardiographic, vascular and clinical effects of a medical food bar enriched with L-arginine and a combination of other nutrients known to enhance endothelium-derived nitric oxide (NO) in patients with stable angina...
  64. ncbi request reprint Effects of intensive versus moderate lipid-lowering therapy on myocardial ischemia in older patients with coronary heart disease: results of the Study Assessing Goals in the Elderly (SAGE)
    Prakash Deedwania
    UCSF School of Medicine, San Francisco, Calif, USA
    Circulation 115:700-7. 2007
    ..However, no studies to date have assessed intensive versus moderate statin therapy in older patients with stable coronary syndromes...
  65. ncbi request reprint From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I
    Morteza Naghavi
    The Center for Vulnerable Plaque Research, University of Texas Houston, The Texas Heart Institute, and President Bush Center for Cardiovascular Health, Memorial Hermann Hospital, Houston, USA
    Circulation 108:1664-72. 2003
    ..We encourage healthcare policy makers to promote translational research for screening and treatment of vulnerable patients...
  66. ncbi request reprint A multifaceted search for the presence of high-risk, vulnerable plaque
    Peter H Stone
    Curr Opin Cardiol 17:613-5. 2002
  67. ncbi request reprint Early glycoprotein IIb/IIIa inhibitors in patients with non-ST-segment elevation myocardial infarction: are we ready to open the floodgates?
    Peter H Stone
    J Am Coll Cardiol 42:54-6. 2003
  68. ncbi request reprint Cardiovascular risks from fine particulate air pollution
    Douglas W Dockery
    N Engl J Med 356:511-3. 2007
  69. ncbi request reprint C-reactive protein to identify early risk for development of calcific aortic stenosis: right marker? Wrong time?
    Peter H Stone
    J Am Coll Cardiol 50:1999-2001. 2007
  70. ncbi request reprint Decreased sleep in heart failure: are medications to blame?
    Frank A J L Scheer
    Arch Intern Med 167:1098-9; author reply 1099-100. 2007