E M Stoffel

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Lynch Syndrome/Hereditary Non-polyposis Colorectal Cancer (HNPCC)
    E M Stoffel
    Division of Gastroenterology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    Minerva Gastroenterol Dietol 56:45-53. 2010
  2. pmc Prevalence and predictors of appropriate colorectal cancer surveillance in Lynch syndrome
    Elena M Stoffel
    Division of Gastroenterology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Am J Gastroenterol 105:1851-60. 2010
  3. pmc Chromoendoscopy detects more adenomas than colonoscopy using intensive inspection without dye spraying
    Elena M Stoffel
    Division of Gastroenterology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Cancer Prev Res (Phila) 1:507-13. 2008
  4. pmc Missed adenomas during colonoscopic surveillance in individuals with Lynch Syndrome (hereditary nonpolyposis colorectal cancer)
    Elena M Stoffel
    Division of Gastroenterology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer Prev Res (Phila) 1:470-5. 2008
  5. pmc Sharing genetic test results in Lynch syndrome: communication with close and distant relatives
    Elena M Stoffel
    Division of Gastroenterology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Clin Gastroenterol Hepatol 6:333-8. 2008
  6. doi request reprint Phenotype comparison of MLH1 and MSH2 mutation carriers in a cohort of 1,914 individuals undergoing clinical genetic testing in the United States
    Fay Kastrinos
    Division of Gastroenterology, Brigham and Women s Hospital, Boston, Massachusetts, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:2044-51. 2008
  7. ncbi request reprint Prediction of MLH1 and MSH2 mutations in Lynch syndrome
    Judith Balmana
    Population Sciences Division, Dana Farber Cancer Institute, and Division of Gastroenterology, Boston, Mass 02115, USA
    JAMA 296:1469-78. 2006
  8. pmc Colorectal cancer risk perception on the basis of genetic test results in individuals at risk for Lynch syndrome
    Shilpa Grover
    Division of Gastroenterology, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    J Clin Oncol 27:3981-6. 2009
  9. pmc Development and validation of a colon cancer risk assessment tool for patients undergoing colonoscopy
    Fay Kastrinos
    Division of Gastroenterology, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Am J Gastroenterol 104:1508-18. 2009
  10. ncbi request reprint Attitudes toward prenatal genetic testing in patients with familial adenomatous polyposis
    Fay Kastrinos
    Division of Gastroenterology, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    Am J Gastroenterol 102:1284-90. 2007

Research Grants

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Lynch Syndrome/Hereditary Non-polyposis Colorectal Cancer (HNPCC)
    E M Stoffel
    Division of Gastroenterology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    Minerva Gastroenterol Dietol 56:45-53. 2010
    ..Colonoscopy at frequent intervals has been shown to be effective in reducing morbidity and mortality from Lynch-associated colorectal cancer...
  2. pmc Prevalence and predictors of appropriate colorectal cancer surveillance in Lynch syndrome
    Elena M Stoffel
    Division of Gastroenterology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Am J Gastroenterol 105:1851-60. 2010
    ..Lynch syndrome (LS) is a hereditary cancer syndrome that conveys a high risk of colorectal cancer (CRC). Guidelines recommend colonoscopy every 1 to 2 years. There is limited information about screening compliance in this high-risk group...
  3. pmc Chromoendoscopy detects more adenomas than colonoscopy using intensive inspection without dye spraying
    Elena M Stoffel
    Division of Gastroenterology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Cancer Prev Res (Phila) 1:507-13. 2008
    ..Chromoendoscopy detected more polyps missed by standard colonoscopy than did intensive inspection. The clinical significance of these small missed lesions warrants further study...
  4. pmc Missed adenomas during colonoscopic surveillance in individuals with Lynch Syndrome (hereditary nonpolyposis colorectal cancer)
    Elena M Stoffel
    Division of Gastroenterology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer Prev Res (Phila) 1:470-5. 2008
    ..We evaluated the adenoma miss rate of conventional colonoscopy in patients with Lynch syndrome, and compared the sensitivity of chromoendoscopy versus intensive inspection for detecting polyps missed by conventional colonoscopy...
  5. pmc Sharing genetic test results in Lynch syndrome: communication with close and distant relatives
    Elena M Stoffel
    Division of Gastroenterology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Clin Gastroenterol Hepatol 6:333-8. 2008
    ..Clinical genetic testing can help direct cancer screening for members of Lynch syndrome families; however, there is limited information about family communication of genetic test results...
  6. doi request reprint Phenotype comparison of MLH1 and MSH2 mutation carriers in a cohort of 1,914 individuals undergoing clinical genetic testing in the United States
    Fay Kastrinos
    Division of Gastroenterology, Brigham and Women s Hospital, Boston, Massachusetts, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:2044-51. 2008
    ..We examined the phenotypic differences between MLH1 and MSH2 gene mutation carriers and whether mutation type (point versus large rearrangement) affected phenotypic expression...
  7. ncbi request reprint Prediction of MLH1 and MSH2 mutations in Lynch syndrome
    Judith Balmana
    Population Sciences Division, Dana Farber Cancer Institute, and Division of Gastroenterology, Boston, Mass 02115, USA
    JAMA 296:1469-78. 2006
    ..Lynch syndrome is caused primarily by mutations in the mismatch repair genes MLH1 and MSH2...
  8. pmc Colorectal cancer risk perception on the basis of genetic test results in individuals at risk for Lynch syndrome
    Shilpa Grover
    Division of Gastroenterology, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    J Clin Oncol 27:3981-6. 2009
    ..This study examines colorectal cancer (CRC) risk perception in individuals tested for MMR mutations and identifies the factors associated with an appropriate interpretation of their cancer risk...
  9. pmc Development and validation of a colon cancer risk assessment tool for patients undergoing colonoscopy
    Fay Kastrinos
    Division of Gastroenterology, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Am J Gastroenterol 104:1508-18. 2009
    ..Our aim was to develop a simple, preprocedural risk assessment tool to identify who may be at highest risk for CRC...
  10. ncbi request reprint Attitudes toward prenatal genetic testing in patients with familial adenomatous polyposis
    Fay Kastrinos
    Division of Gastroenterology, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    Am J Gastroenterol 102:1284-90. 2007
    ..If a mutation is identified, prenatal testing can reveal whether an embryo or fetus is affected. We conducted a pilot study to assess FAP patients' attitudes toward prenatal testing...
  11. doi request reprint Risk of pancreatic cancer in families with Lynch syndrome
    Fay Kastrinos
    Department of Internal Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    JAMA 302:1790-5. 2009
    ..A number of extracolonic tumors have been associated with the disorder, including pancreatic cancer; however, the risk of pancreatic cancer in Lynch syndrome is uncertain and not quantified...
  12. ncbi request reprint Physician assessment of family cancer history and referral for genetic evaluation in colorectal cancer patients
    Shilpa Grover
    Population Sciences Division, Dana Farber Cancer Institute, Boston, MA 02114, USA
    Clin Gastroenterol Hepatol 2:813-9. 2004
    ..Our aim was to determine the concordance of family history assessments made by physicians with patients' self-reports and the frequency of referral for genetic evaluation in high-risk colorectal cancer (CRC) patients...
  13. ncbi request reprint Adenomas in young patients: what is the optimal evaluation?
    Elena M Stoffel
    Am J Gastroenterol 100:1150-3. 2005
    ....

Research Grants2

  1. Genetic Testing and Cancer Screening in Hereditary Cancer Syndromes
    Elena Stoffel; Fiscal Year: 2007
    ..Identification of factors which impact cancer screening behaviors and cancer risk stratification will lead to improvements in clinical care for all patients at risk for CRC. ..