E A Stewart

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Clinical outcomes of focused ultrasound surgery for the treatment of uterine fibroids
    Elizabeth A Stewart
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Fertil Steril 85:22-9. 2006
  2. ncbi request reprint The genetics of uterine leiomyomata: what clinicians need to know
    Elizabeth A Stewart
    Center for Uterine Fibroids, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Obstet Gynecol 107:917-21. 2006
  3. ncbi request reprint Uterine fibroids
    E A Stewart
    Center for Uterine Fibroids, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Lancet 357:293-8. 2001
  4. ncbi request reprint Gonadotropins and the uterus: is there a gonad-independent pathway?
    E A Stewart
    Center for Uterine Fibroids, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Soc Gynecol Investig 8:319-26. 2001
  5. ncbi request reprint Predictors of subsequent surgery for uterine leiomyomata after abdominal myomectomy
    Elizabeth A Stewart
    Center for Uterine Fibroids and Ob Gyn Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Obstet Gynecol 99:426-32. 2002
  6. ncbi request reprint New concepts in the treatment of uterine leiomyomas
    E A Stewart
    Department of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Obstet Gynecol 92:624-7. 1998
  7. ncbi request reprint Messenger ribonucleic acid for the gonadal luteinizing hormone/human chorionic gonadotropin receptor is not present in human endometrium
    E A Stewart
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital and Havard Medical School, Boston, Massachusetts 02115, USA
    Fertil Steril 71:368-72. 1999
  8. ncbi request reprint Prolactin is an autocrine or paracrine growth factor for human myometrial and leiomyoma cells
    R A Nowak
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
    Gynecol Obstet Invest 48:127-32. 1999
  9. pmc Molecular and cytogenetic characterization of plexiform leiomyomata provide further evidence for genetic heterogeneity underlying uterine fibroids
    Jennelle C Hodge
    Brigham and Women s Hospital, Department of Obstetrics and Gynecology and Reproductive Biology, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    Am J Pathol 172:1403-10. 2008
  10. ncbi request reprint Does the phase of menstrual cycle affect MR-guided focused ultrasound surgery of uterine leiomyomas?
    Minna J So
    Department of Radiology, Brigham and Women s Hospital Harvard Medical School, Boston, MA, USA
    Eur J Radiol 59:203-7. 2006

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Clinical outcomes of focused ultrasound surgery for the treatment of uterine fibroids
    Elizabeth A Stewart
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Fertil Steril 85:22-9. 2006
    ..To assess outcomes at 6 and 12 months after magnetic resonance-guided focused ultrasound surgery (MRgFUS) for symptomatic uterine leiomyomas...
  2. ncbi request reprint The genetics of uterine leiomyomata: what clinicians need to know
    Elizabeth A Stewart
    Center for Uterine Fibroids, Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Obstet Gynecol 107:917-21. 2006
    ..The current role of family medical history and future implications of genes relevant to leiomyoma biology will be reviewed...
  3. ncbi request reprint Uterine fibroids
    E A Stewart
    Center for Uterine Fibroids, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Lancet 357:293-8. 2001
    ..New research into the basic biology of these neoplasms may add new treatment options for the future as the role of growth factors and genetic mutations in these tumours are better understood...
  4. ncbi request reprint Gonadotropins and the uterus: is there a gonad-independent pathway?
    E A Stewart
    Center for Uterine Fibroids, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Soc Gynecol Investig 8:319-26. 2001
    ..I will review the evidence regarding gonadotropin action in nongonadal tissues, primarily the uterus. In addition, the data regarding receptors will be reviewed. Finally, the clinical areas informed by this information will be explored...
  5. ncbi request reprint Predictors of subsequent surgery for uterine leiomyomata after abdominal myomectomy
    Elizabeth A Stewart
    Center for Uterine Fibroids and Ob Gyn Epidemiology Center, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Obstet Gynecol 99:426-32. 2002
    ..To study factors associated with an increased risk of subsequent surgery in a cohort of women undergoing abdominal myomectomy...
  6. ncbi request reprint New concepts in the treatment of uterine leiomyomas
    E A Stewart
    Department of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Obstet Gynecol 92:624-7. 1998
    ..As we gain understanding of the molecular events that cause benign gynecologic conditions such as leiomyomas, safer and more effective treatments might be found as we enter the 21st century...
  7. ncbi request reprint Messenger ribonucleic acid for the gonadal luteinizing hormone/human chorionic gonadotropin receptor is not present in human endometrium
    E A Stewart
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital and Havard Medical School, Boston, Massachusetts 02115, USA
    Fertil Steril 71:368-72. 1999
    ..To determine whether messenger RNA for the gonadal LH/hCG receptor is present in human endometrium with the use of reverse-transcriptase polymerase chain reaction...
  8. ncbi request reprint Prolactin is an autocrine or paracrine growth factor for human myometrial and leiomyoma cells
    R A Nowak
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
    Gynecol Obstet Invest 48:127-32. 1999
    ..To test the hypothesis that prolactin (PRL) acts as a mitogenic growth factor for human leiomyoma and myometrial cells...
  9. pmc Molecular and cytogenetic characterization of plexiform leiomyomata provide further evidence for genetic heterogeneity underlying uterine fibroids
    Jennelle C Hodge
    Brigham and Women s Hospital, Department of Obstetrics and Gynecology and Reproductive Biology, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    Am J Pathol 172:1403-10. 2008
    ..We further suggest that plexiform UL should be classified among tumors with extensive hyalinization rather than with "true" epithelioid smooth muscle neoplasms...
  10. ncbi request reprint Does the phase of menstrual cycle affect MR-guided focused ultrasound surgery of uterine leiomyomas?
    Minna J So
    Department of Radiology, Brigham and Women s Hospital Harvard Medical School, Boston, MA, USA
    Eur J Radiol 59:203-7. 2006
    ..To determine whether the phase of menstrual cycle at the time of MR-guided focused ultrasound surgery (MRgFUS) treatment for uterine leiomyomas affects treatment outcome...
  11. pmc Uterine leiomyomas: MR imaging-based thermometry and thermal dosimetry during focused ultrasound thermal ablation
    Nathan Mcdannold
    Department of Radiology, Harvard Medical School, Brigham and Women s Hospital, 221 Longwood Ave LMRC, 007c, Boston, MA 02115, USA
    Radiology 240:263-72. 2006
    ..To retrospectively evaluate magnetic resonance (MR) imaging-based thermometry and thermal dosimetry during focused ultrasound treatments of uterine leiomyomas (ie, fibroids)...
  12. ncbi request reprint Development of a research agenda for uterine artery embolization: proceedings from a multidisciplinary research consensus panel
    James B Spies
    Department of Radiology, Georgetown University Hospital, Washington, DC 20007 2113, USA
    J Vasc Interv Radiol 17:1871-9. 2006
  13. pmc Polycystic ovary syndrome and risk of uterine leiomyomata
    Lauren A Wise
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    Fertil Steril 87:1108-15. 2007
    ..To examine the association between polycystic ovary syndrome (PCOS) and the risk of uterine leiomyomata (UL)...
  14. ncbi request reprint Uterine leiomyomas: MR imaging-guided focused ultrasound surgery--results of different treatment protocols
    Fiona M Fennessy
    Department of Radiology, Harvard Medical School Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Radiology 243:885-93. 2007
    ..To prospectively assess patient response (after 12 months) to magnetic resonance (MR) imaging-guided focused ultrasound surgery in treatment of uterine leiomyomas by using two treatment protocols...
  15. ncbi request reprint Sustained relief of leiomyoma symptoms by using focused ultrasound surgery
    Elizabeth A Stewart
    Departments of Obstetrics, Gynecology and Reproductive Biology and Radiology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Obstet Gynecol 110:279-87. 2007
    ..To assess several measures of the long-term outcome of magnetic resonance-guided focused ultrasound surgery for symptomatic uterine leiomyomata...
  16. pmc Perceived racial discrimination and risk of uterine leiomyomata
    Lauren A Wise
    Slone Epidemiology Center, Boston University, Boston, MA 02215, USA
    Epidemiology 18:747-57. 2007
    ..Black women also report higher levels of racial discrimination. We evaluated the hypothesis that greater exposure to racism increases myoma risk in black women...
  17. pmc The impact of race as a risk factor for symptom severity and age at diagnosis of uterine leiomyomata among affected sisters
    Karen L Huyck
    Department of Pathology, University of Vermont College of Medicine, Burlington, VT, USA
    Am J Obstet Gynecol 198:168.e1-9. 2008
    ..The objective of the study was to identify risk factors for uterine leiomyomata (UL) in a racially diverse population of women with a family history of UL, and to evaluate their contribution to disease severity and age at diagnosis...
  18. doi request reprint Magnetic resonance-guided focused ultrasound surgery
    Susan B A Hudson
    Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, College of Medicine, Mayo Clinic, Rochester, Minnesota 55901, USA
    Clin Obstet Gynecol 51:159-66. 2008
    ..Magnetic resonance-guided focused ultrasound surgery is a new noninvasive therapy that has been proven to be both safe and efficacious in the treatment of fibroids...
  19. ncbi request reprint Avoiding treatment of leiomyosarcomas: the role of magnetic resonance in focused ultrasound surgery
    Amber Samuel
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Fertil Steril 90:850.e9-12. 2008
    ..To report early diagnosis of a uterine leiomyosarcoma during screening for magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) for leiomyomas...
  20. ncbi request reprint Uterine artery embolization versus myomectomy: a multicenter comparative study
    Scott C Goodwin
    Department of Veterans Affairs, The University of California, Los Angeles, California, USA
    Fertil Steril 85:14-21. 2006
    ..To determine whether there is significant quality of life score improvement after uterine artery embolization (UAE) and to compare UAE and myomectomy outcomes...
  21. ncbi request reprint MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study
    Clare M C Tempany
    Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    Radiology 226:897-905. 2003
    ..MR imaging-guided focused ultrasound causes thermocoagulation and necrosis in uterine leiomyomas and is feasible and safe, without serious consequences...
  22. ncbi request reprint Focused ultrasound treatment of uterine fibroid tumors: safety and feasibility of a noninvasive thermoablative technique
    Elizabeth A Stewart
    Departments of Obstetrics, Gynecology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Am J Obstet Gynecol 189:48-54. 2003
    ..The purpose of this study was to determine the safety and efficacy of focused ultrasound surgery with magnetic resonance imaging guidance for the noninvasive treatment of uterine leiomyomas...
  23. pmc Reproductive factors, hormonal contraception, and risk of uterine leiomyomata in African-American women: a prospective study
    Lauren A Wise
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02215, USA
    Am J Epidemiol 159:113-23. 2004
    ..No consistent patterns were observed for other forms of hormonal contraception. Reproductive history is an important determinant of leiomyomata risk in premenopausal US Black women. Progestin-only injectables may reduce risk...
  24. pmc Uterine leiomyomas: MR imaging-guided focused ultrasound surgery--imaging predictors of success
    Zsuzsanna M Lénárd
    Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
    Radiology 249:187-94. 2008
    ..To retrospectively assess the magnetic resonance (MR) imaging predictors of success at reducing uterine leiomyoma volume and achieving patient symptom relief 12 months after MR imaging-guided focused ultrasound surgery...
  25. pmc Risk of uterine leiomyomata in relation to tobacco, alcohol and caffeine consumption in the Black Women's Health Study
    Lauren A Wise
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Hum Reprod 19:1746-54. 2004
    ..Tobacco, alcohol and caffeine consumption may influence risk of uterine leiomyomata via changes in ovarian function or hormone metabolism...
  26. ncbi request reprint Involvement of fumarate hydratase in nonsyndromic uterine leiomyomas: genetic linkage analysis and FISH studies
    Karen L Gross
    Department of Pathology, University of Vermont, Burlington, Vermont, USA
    Genes Chromosomes Cancer 41:183-90. 2004
    ..7 at D1S547, P = 0.04). FISH results showed that one copy of FH was absent in 9 of 11 ULs. These data indicate that loss of FH might be a significant event in the pathogenesis of a subset of nonsyndromic ULs...
  27. pmc Age-specific incidence rates for self-reported uterine leiomyomata in the Black Women's Health Study
    Lauren A Wise
    Slone Epidemiology Center, Boston University, Boston, Massachusetts 02215, USA
    Obstet Gynecol 105:563-8. 2005
    ..We estimated overall and age-specific incidence rates for self-reported uterine leiomyomata in a large cohort of African-American women in the United States...
  28. ncbi request reprint Focused ultrasound surgery of intramural leiomyomas may facilitate fertility: a case report
    Miriam M F Hanstede
    Department of Obstetrics, Gynecology, and Reproductive Biology, Boston, Massachusetts, USA
    Fertil Steril 88:497.e5-7. 2007
    ..To describe a successful pregnancy after a change in configuration of the endometrial cavity after magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) for leiomyomas...
  29. ncbi request reprint Granulocyte macrophage colony-stimulating factor in adenomyosis and autologous endometrium
    Anthony M Propst
    Department of Obstetrics, Gynecology, and Reproductive Biology, Division of Reproductive Medicine, Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Soc Gynecol Investig 9:93-7. 2002
    ..We determined whether adenomyosis expresses GM-CSF, and if present, compared GM-CSF protein expression in adenomyosis with that in autologous endometrium...
  30. ncbi request reprint Does the introduction of new technology change population demographics? Minimally invasive technologies and endometrial polyps
    Norma F Chavez
    Center for Uterine Fibroids, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    Gynecol Obstet Invest 54:217-20. 2002
    ..To determine if the characteristics of women with endometrial polyps changed as minimally invasive modalities for diagnosis and surgical treatment were integrated to our clinical practice...
  31. ncbi request reprint Uterine fibroids: the elephant in the room
    Cheryl Lyn Walker
    Department of Carcinogenesis, University of Texas and MD Anderson Cancer Center, Park Road 1C, Smithville, TX 78957, USA
    Science 308:1589-92. 2005
    ..As new therapies are developed, the heterogeneity of this disease becomes therapeutically relevant. An awareness of the role of genetics, the extracellular matrix, and hormones in tumor etiology is key to understanding this disease...
  32. ncbi request reprint Neuropathic uterine pain after hysterectomy. A case report
    Norma F Chavez
    Center for Uterine Fibroids, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Reprod Med 48:466-8. 2003
    ..Diabetic neuropathy, postherpetic neuralgia and phantom limb pain are common types of neuropathic pain. It is not commonly recognized in gynecologic practice...
  33. pmc Influence of body size and body fat distribution on risk of uterine leiomyomata in U.S. black women
    Lauren A Wise
    Department of Epidemiology, Harvard School of Public Health, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Epidemiology 16:346-54. 2005
    ..We prospectively investigated the risk of self-reported uterine leiomyomata in relation to body mass index (BMI), weight change, height, waist and hip circumferences, and waist-to-hip ratio in a large cohort of U.S black women...
  34. ncbi request reprint New interventional techniques for adenomyosis
    Jaron Rabinovici
    Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Senior Lecturer, Sackler Medical School, Tel Aviv University, Tel Hashomer 52621, Israel
    Best Pract Res Clin Obstet Gynaecol 20:617-36. 2006
    ..Based on the evidence presented in this chapter it seems that adenomyosis has become an entity that might be treatable by new, minimally invasive or non-invasive treatments...
  35. ncbi request reprint The direct and indirect cost burden of clinically significant and symptomatic uterine fibroids
    David W Lee
    Health Economics and Outcomes Research, GE Healthcare, Waukesha, WI, USA
    J Occup Environ Med 49:493-506. 2007
    ..To estimate direct medical costs and indirect (productivity related) for women age 25 to 54 who had clinically significant and symptomatic uterine fibroids (UF)...