Lynne W Stevenson

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Design of therapy for advanced heart failure
    Lynne Warner Stevenson
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Eur J Heart Fail 7:323-31. 2005
  2. ncbi request reprint Evaluation and monitoring of patients with acute heart failure syndromes
    Anju Nohria
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Am J Cardiol 96:32G-40G. 2005
  3. ncbi request reprint Left ventricular assist device as destination for patients undergoing intravenous inotropic therapy: a subset analysis from REMATCH (Randomized Evaluation of Mechanical Assistance in Treatment of Chronic Heart Failure)
    Lynne Warner Stevenson
    Brigham and Women s Hospital, 75 Francis St, Boston, Mass 02115, USA
    Circulation 110:975-81. 2004
  4. pmc Theodore E. Woodward Award: Coming in out of the rain. Relieving congestion in heart failure
    Lynne Warner Stevenson
    Heart Failure Program, Advanced Heart Disease Section, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Trans Am Clin Climatol Assoc 120:177-87. 2009
  5. pmc Changing preferences for survival after hospitalization with advanced heart failure
    Lynne W Stevenson
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 52:1702-8. 2008
  6. doi request reprint Chronic ambulatory intracardiac pressures and future heart failure events
    Lynne Warner Stevenson
    Advanced Heart Disease Section, Brigham and Women s Hospital, Boston, Mass 02115, USA
    Circ Heart Fail 3:580-7. 2010
  7. doi request reprint Right ventricular dysfunction during intensive pharmacologic unloading persists after mechanical unloading
    Maryse Palardy
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    J Card Fail 16:218-24. 2010
  8. ncbi request reprint Severity of intraoperative tricuspid regurgitation predicts poor late survival following cardiac transplantation
    Curtis A Anderson
    Division of Cardiac Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    Ann Thorac Surg 78:1635-42. 2004
  9. ncbi request reprint Development of circulatory-renal limitations to angiotensin-converting enzyme inhibitors identifies patients with severe heart failure and early mortality
    Michelle Kittleson
    Departments of Medicine and Cardiology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    J Am Coll Cardiol 41:2029-35. 2003
  10. ncbi request reprint Right ventricular dysfunction and adverse outcome in patients with advanced heart failure
    Michael E Field
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    J Card Fail 12:616-20. 2006

Research Grants

  1. Partners Heart Failure Network
    Lynne Stevenson; Fiscal Year: 2007

Detail Information

Publications55

  1. ncbi request reprint Design of therapy for advanced heart failure
    Lynne Warner Stevenson
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Eur J Heart Fail 7:323-31. 2005
    ..To derive maximal benefit from all available therapies, heart failure disease management with collaboration of physicians and specialized nurses offers the greatest benefit to the greatest number of patients with advanced heart failure...
  2. ncbi request reprint Evaluation and monitoring of patients with acute heart failure syndromes
    Anju Nohria
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Am J Cardiol 96:32G-40G. 2005
    ..Development of validated and reproducible noninvasive techniques to monitor patients with acute HF will be an important step in maximizing interventions to improve outcomes in this patient population...
  3. ncbi request reprint Left ventricular assist device as destination for patients undergoing intravenous inotropic therapy: a subset analysis from REMATCH (Randomized Evaluation of Mechanical Assistance in Treatment of Chronic Heart Failure)
    Lynne Warner Stevenson
    Brigham and Women s Hospital, 75 Francis St, Boston, Mass 02115, USA
    Circulation 110:975-81. 2004
    ..This study analyzes, on a post hoc basis, outcomes in patients undergoing inotropic infusions at randomization...
  4. pmc Theodore E. Woodward Award: Coming in out of the rain. Relieving congestion in heart failure
    Lynne Warner Stevenson
    Heart Failure Program, Advanced Heart Disease Section, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Trans Am Clin Climatol Assoc 120:177-87. 2009
    ..The challenge is to intensify not only acute management of heart failure but ambulatory surveillance to allow early intervention and reduce re-hospitalization...
  5. pmc Changing preferences for survival after hospitalization with advanced heart failure
    Lynne W Stevenson
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 52:1702-8. 2008
    ..This study was designed to analyze how patient preferences for survival versus quality-of-life change after hospitalization with advanced heart failure (HF)...
  6. doi request reprint Chronic ambulatory intracardiac pressures and future heart failure events
    Lynne Warner Stevenson
    Advanced Heart Disease Section, Brigham and Women s Hospital, Boston, Mass 02115, USA
    Circ Heart Fail 3:580-7. 2010
    ..The optimal level of chronic ambulatory pressure is unknown. This analysis compared chronic intracardiac pressures to later HF events and sought a threshold above which higher pressures conferred worse outcomes...
  7. doi request reprint Right ventricular dysfunction during intensive pharmacologic unloading persists after mechanical unloading
    Maryse Palardy
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    J Card Fail 16:218-24. 2010
    ..We compared RV size and function after aggressive medical unloading therapy to that achieved in the same patients after 3 months of left ventricular assist device (LVAD) support...
  8. ncbi request reprint Severity of intraoperative tricuspid regurgitation predicts poor late survival following cardiac transplantation
    Curtis A Anderson
    Division of Cardiac Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    Ann Thorac Surg 78:1635-42. 2004
    ..Although significant (2+ to 4+) TR after orthotopic heart transplantation is rare, its influence on long-term survival is unknown, warranting further investigation...
  9. ncbi request reprint Development of circulatory-renal limitations to angiotensin-converting enzyme inhibitors identifies patients with severe heart failure and early mortality
    Michelle Kittleson
    Departments of Medicine and Cardiology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    J Am Coll Cardiol 41:2029-35. 2003
    ..This study examined the hypothesis that patients who develop angiotensin-converting enzyme inhibitor intolerance attributable to circulatory-renal limitations (CRLimit) have more severe underlying disease and worse outcome...
  10. ncbi request reprint Right ventricular dysfunction and adverse outcome in patients with advanced heart failure
    Michael E Field
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    J Card Fail 12:616-20. 2006
    ....
  11. pmc Tai chi in patients with heart failure with preserved ejection fraction
    Gloria Y Yeh
    Osher Center for Integrative Medicine, Harvard Medical School, Boston, MA, USA
    Congest Heart Fail 19:77-84. 2013
    ..3 mL/kg/min vs 9.4 mL/kg/min, P<.01), respiratory rate, and heart rate. TC is feasible and safe in HFPEF. Therepeutic endpoints appear similar with TC relative to aerobic exercise despite a lower aerobic training workload...
  12. doi request reprint Patient expectations from implantable defibrillators to prevent death in heart failure
    Garrick C Stewart
    Division of Cardiovascular Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Card Fail 16:106-13. 2010
    ..This study examined patient expectations from ICDs for primary prevention of sudden death in HF...
  13. doi request reprint Mismatch of right- and left-sided filling pressures in chronic heart failure
    Patricia Campbell
    Advanced Heart Disease Section, Brigham and Women s Hospital, Boston, Massachusetts 02446, USA
    J Card Fail 17:561-8. 2011
    ..We determined the prevalence of R-L mismatch in the current era and investigated whether mismatch might be identified from clinical information...
  14. ncbi request reprint Relation of right ventricular peak systolic pressure to major adverse events in patients undergoing cardiac resynchronization therapy
    Usha B Tedrow
    Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Am J Cardiol 97:1737-40. 2006
    ..22, 95% confidence interval 1.54 to 11.6) remained significant. In conclusion, despite resynchronization, patients with high RV pressures have significantly decreased survival after adjusting for significant contributing influences...
  15. pmc Reduction in mitral regurgitation during therapy guided by measured filling pressures in the ESCAPE trial
    Maryse Palardy
    Brigham and Women s Hospital, Boston, Mass Duke Medical Center, Durham, NC, USA
    Circ Heart Fail 2:181-8. 2009
    ....
  16. doi request reprint Cardiorenal interactions: insights from the ESCAPE trial
    Anju Nohria
    Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Coll Cardiol 51:1268-74. 2008
    ....
  17. doi request reprint Thresholds of physical activity and life expectancy for patients considering destination ventricular assist devices
    Garrick C Stewart
    Division of Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Heart Lung Transplant 28:863-9. 2009
    ..Debate continues about selection of HF patients for LVAD therapy. We sought to determine what level of personal risk and disability HF patients thought would warrant LVAD therapy...
  18. ncbi request reprint Clinical assessment identifies hemodynamic profiles that predict outcomes in patients admitted with heart failure
    Anju Nohria
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    J Am Coll Cardiol 41:1797-804. 2003
    ..Profiles based on clinical assessment of congestion and perfusion at the time of hospitalization were compared with subsequent outcomes...
  19. doi request reprint Handheld echocardiography offers rapid assessment of clinical volume status
    Viviane T Q Nguyen
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am Heart J 156:537-42. 2008
    ..In this study, we evaluated the feasibility and accuracy of handheld echocardiography by a nonexpert for potential use in the point of care evaluation of compensation...
  20. ncbi request reprint Angiotensin-converting enzyme inhibitors and angiotensin II type I receptor blockers in the management of congestive heart failure patients: what have we learned from recent clinical trials?
    Lisa Mielniczuk
    Department of Medicine, Cardiovascular Division, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Curr Opin Cardiol 20:250-5. 2005
    ....
  21. pmc Hospice, opiates, and acute care service use among the elderly before death from heart failure or cancer
    Soko Setoguchi
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Am Heart J 160:139-44. 2010
    ..Advances in heart failure (HF) treatments have prolonged survival, but more patients die of HF than of any type of cancer. Little is known about the current practice in end-of-life (EOL) care in HF...
  22. pmc Maximum potential benefit of implantable defibrillators in preventing sudden death after hospital admission because of heart failure
    Soko Setoguchi
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02130, USA
    CMAJ 180:611-6. 2009
    ..However, criteria to identify those who would benefit most from this therapy are lacking. We assessed the maximum potential benefit of preventing sudden death in patients with repeated hospital admissions because of heart failure...
  23. ncbi request reprint Atrial fibrillation in heart failure: epidemiology, pathophysiology, and rationale for therapy
    William H Maisel
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Am J Cardiol 91:2D-8D. 2003
    ..It will be critical to define and plan therapies specifically for those patients with AF, HF, and preserved ejection fraction in addition to the population with low ejection fraction that has dominated previous investigations...
  24. doi request reprint Impaired heart rate responses and exercise capacity in heart failure patients with paced baseline rhythms
    Amaar Ujeyl
    Cardiovascular Division and Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    J Card Fail 17:188-95. 2011
    ..We hypothesized that many HF patients dependent on pacing have suboptimal heart rate responses and associated limitations in exercise capacity...
  25. ncbi request reprint Risk factors and outcomes for 'vasoplegia syndrome' following cardiac transplantation
    John G Byrne
    Division of Cardiac Surgery, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Eur J Cardiothorac Surg 25:327-32. 2004
    ..The objective of this retrospective study was to identify the risk factors contributing to the development of vasoplegia syndrome after OHT in order to provide potential algorithms for its management...
  26. ncbi request reprint Neurohormonal activation rapidly decreases after intravenous therapy with diuretics and vasodilators for class IV heart failure
    Wendy Johnson
    Brigham and Women s Hospital, Cardiovascular Division, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 39:1623-9. 2002
    ..BACKGROUND; Elevated vasoactive neurohormone levels in chronic HF have adverse prognostic impact and may be targeted by specific therapies...
  27. ncbi request reprint Effects of tai chi mind-body movement therapy on functional status and exercise capacity in patients with chronic heart failure: a randomized controlled trial
    Gloria Y Yeh
    Division for Research and Education in Complementary and Integrative Medical Therapies, Harvard Medical School, Boston, Massachusetts 02215, USA
    Am J Med 117:541-8. 2004
    ..To examine the effects of a 12-week tai chi program on quality of life and exercise capacity in patients with heart failure...
  28. doi request reprint Third INTERMACS Annual Report: the evolution of destination therapy in the United States
    James K Kirklin
    Cardiovascular Division, University of Alabama at Birmingham, Alabama 35294, USA
    J Heart Lung Transplant 30:115-23. 2011
    ..The current 1-year survival of 75% with continuous-flow destination therapy provides a benchmark for the evolving application of this therapy...
  29. ncbi request reprint Incidence, predictors at admission, and impact of worsening renal function among patients hospitalized with heart failure
    Daniel E Forman
    Section of Cardiology, Boston Medical Center, Boston, Massachusetts 02188, USA
    J Am Coll Cardiol 43:61-7. 2004
    ..The goal of this study was to determine the prevalence of worsening renal function (WRF) among hospitalized heart failure (HF) patients, clinical predictors of WRF, and hospital outcomes associated with WRF...
  30. ncbi request reprint Clinical use of inotropic therapy for heart failure: looking backward or forward? Part II: chronic inotropic therapy
    Lynne Warner Stevenson
    Division of Cardiology, Brigham and Women s Hospital, 75 Francis St, Boston, Mass 02115, USA
    Circulation 108:492-7. 2003
  31. ncbi request reprint Repeated hospitalizations predict mortality in the community population with heart failure
    Soko Setoguchi
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02130, USA
    Am Heart J 154:260-6. 2007
    ..The impact of repeated heart failure (HF) hospitalization on mortality has not been studied for a large community population with HF. We aimed to characterize survival of patients in relation to the number of HF hospitalizations...
  32. ncbi request reprint The cul-de-sac at the end of the road
    Lynne Warner Stevenson
    Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Card Fail 9:188-91. 2003
  33. doi request reprint INTERMACS and MedaMACS: how will they guide future therapy?
    Garrick C Stewart
    Brigham and Women s Hospital, Center for Advanced Heart Disease, 75 Francis Street, Boston, MA, USA
    Curr Cardiol Rep 15:394. 2013
    ..Together INTERMACS and MedaMACS will leverage the power of observation research to guide patient-centered decisions about mechanical circulatory support. ..
  34. doi request reprint The association between high-dose diuretics and clinical stability in ambulatory chronic heart failure patients
    Lisa M Mielniczuk
    Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Card Fail 14:388-93. 2008
    ..In chronic heart failure (HF), diuretic doses increase as the disease progresses, often after hospitalization for instability, and have been associated with worsening renal function and increased mortality...
  35. ncbi request reprint Ventricular assist devices for durable support
    Lynne Warner Stevenson
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Circulation 112:e111-5. 2005
  36. ncbi request reprint Medical management of advanced heart failure
    Anju Nohria
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Tower 3 A, Boston, MA 02115, USA
    JAMA 287:628-40. 2002
    ..Advanced heart failure, defined as persistence of limiting symptoms despite therapy with agents of proven efficacy, accounts for the majority of morbidity and mortality in heart failure...
  37. doi request reprint INTERMACS profiles of advanced heart failure: the current picture
    Lynne Warner Stevenson
    Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Heart Lung Transplant 28:535-41. 2009
    ....
  38. ncbi request reprint Beta-blockers for stable heart failure
    Lynne Warner Stevenson
    Brigham and Women s Hospital, Boston, MA 02115, USA
    N Engl J Med 346:1346-7. 2002
  39. ncbi request reprint Clinical use of inotropic therapy for heart failure: looking backward or forward? Part I: inotropic infusions during hospitalization
    Lynne Warner Stevenson
    Division of Cardiology, Brigham and Women s Hospital, 75 Francis St, Boston, Mass 02115, USA
    Circulation 108:367-72. 2003
  40. ncbi request reprint Left ventricular assist devices: bridges to transplantation, recovery, and destination for whom?
    Lynne Warner Stevenson
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, Mass 02115, USA
    Circulation 108:3059-63. 2003
  41. ncbi request reprint Are hemodynamic goals viable in tailoring heart failure therapy? Hemodynamic goals are relevant
    Lynne Warner Stevenson
    Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Circulation 113:1020-7; discussion 1033. 2006
  42. ncbi request reprint Selecting patients for discussion of the ICD as primary prevention for sudden death in heart failure
    Lynne Warner Stevenson
    Advanced Heart Disease Section, Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Card Fail 12:407-12. 2006
    ..These estimates are presented in the context of adverse events, including unnecessary shocks, and the possibility that circumstances may arise for which the defibrillator may be inactivated to allow natural death...
  43. doi request reprint Rhythm control versus rate control for atrial fibrillation and heart failure
    Denis Roy
    Montreal Heart Institute and the Université de Montréal, Montreal, QC H1T 1C8, Canada
    N Engl J Med 358:2667-77. 2008
    ..However, the benefits and risks of this approach have not been adequately studied...
  44. ncbi request reprint Relationship between heart failure treatment and development of worsening renal function among hospitalized patients
    Javed Butler
    Vanderbilt University, Nashville, Tenn, USA
    Am Heart J 147:331-8. 2004
    ..Whether treatment for HF contributes to WRF is unknown. In this study, we sought to assess whether acute treatment for patients who were hospitalized with HF contributes to WRF...
  45. ncbi request reprint ACC/AHA guidelines for the evaluation and management of chronic heart failure in the adult: executive summary
    Sharon A Hunt
    American College of Cardiology American Heart Association Task Force on Practice Guidelines
    J Heart Lung Transplant 21:189-203. 2002
  46. ncbi request reprint The prognostic importance of different definitions of worsening renal function in congestive heart failure
    Stephen S Gottlieb
    Division of Cardiology, University of Maryland School of Medicine and the D V A Medical Center, Baltimore, Maryland 21201, USA
    J Card Fail 8:136-41. 2002
    ..We therefore compared the prognostic importance of various definitions of worsening renal function in 1,002 patients hospitalized for congestive heart failure (CHF)...
  47. doi request reprint ACC/AHA/HRS 2008 Guidelines for device-based therapy of cardiac rhythm abnormalities
    Andrew E Epstein
    Heart Rhythm 5:e1-62. 2008
  48. doi request reprint ACC/AHA/HRS 2008 guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: executive summary
    Andrew E Epstein
    Heart Rhythm 5:934-55. 2008
  49. ncbi request reprint The Second Follow-up Serial Infusions of Nesiritide (FUSION II) trial for advanced heart failure: study rationale and design
    Clyde W Yancy
    Baylor University Medical Center, Heart and Vascular Institute, Dallas, TX 75246, USA
    Am Heart J 153:478-84. 2007
    ..Within a prespecified subset of high-risk patients, a potential signal of benefit on a combined end point of mortality and cardiovascular hospitalization was identified...
  50. ncbi request reprint On the fledgling field of mechanical circulatory support
    Lynne Warner Stevenson
    J Am Coll Cardiol 50:748-51. 2007
  51. ncbi request reprint Torrent or torment from the tubules? Challenge of the cardiorenal connections
    Lynne Warner Stevenson
    J Am Coll Cardiol 45:2004-7. 2005
  52. ncbi request reprint Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: a report from the Acute Decompensated Heart Failure National Registry (ADHERE) Database
    Clyde W Yancy
    Division of Cardiology, Department of Medicine, University of Texas Southwest Medical Center, Dallas, Texas 75390 9047, USA
    J Am Coll Cardiol 47:76-84. 2006
    ..Medical treatment strategies for patients with preserved systolic function are inconsistent and reflect the need for efficacious evidence-based treatment regimens...
  53. doi request reprint Transition from chronic compensated to acute decompensated heart failure: pathophysiological insights obtained from continuous monitoring of intracardiac pressures
    Michael R Zile
    Department of Medicine, Division of Cardiology, Medical University of South Carolina, Charleston, SC 29425, USA
    Circulation 118:1433-41. 2008
    ..The purpose of this study was to use echocardiographic and implantable hemodynamic monitor data to examine the pathophysiology of chronic compensated and acute decompensated HF in SHF versus DHF patients...
  54. ncbi request reprint Mapping the journey
    Lynne Warner Stevenson
    J Am Coll Cardiol 47:1612-4. 2006
  55. ncbi request reprint Case records of the Massachusetts General Hospital. Case 37-2007. A 47-year-old man with left ventricular dysfunction after heart transplantation
    Marc J Semigran
    Cardiology Division, Massachusetts General Hospital, USA
    N Engl J Med 357:2286-97. 2007

Research Grants2

  1. Partners Heart Failure Network
    Lynne Stevenson; Fiscal Year: 2007
    ..End of Abstract) ..