Research Topics
Genomes and GenesSpecies | Elizabeth K SpeliotesSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
Research Grants
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Detail Information
Publications
PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic diseaseElizabeth K Speliotes
Department of Gastroenterology, Massachusetts General Hospital, Boston, MA 02114, USA
Hepatology 52:904-12. 2010..CONCLUSION: Genetic variation at PNPLA3 confers a markedly increased risk of increasingly severe histological features of NAFLD, without a strong effect on metabolic syndrome component traits...
Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat: the Framingham Heart StudyElizabeth K Speliotes
Department of Gastroenterology, Massachusetts General Hospital, Boston, MA 02114, USA
Hepatology 51:1979-87. 2010..This work begins to dissect the specific links between fat depots and metabolic disease...
Intramuscular fat and associations with metabolic risk factors in the Framingham Heart StudyKate E Therkelsen
Boston University School of Medicine, Boston, MA, USA
Arterioscler Thromb Vasc Biol 33:863-70. 2013..CONCLUSIONS: MA was associated with metabolic risk factors, but most of these associations were lost after adjustment for BMI or VAT. However, a unique association remained for metabolic syndrome in women and lipids in men...
Common body mass index-associated variants confer risk of extreme obesityChris Cotsapas
Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA
Hum Mol Genet 18:3502-7. 2009..Our results suggest that variants influencing BMI also contribute to severe obesity, a condition at the extreme of the phenotypic spectrum rather than a distinct condition...
Research Grants
- Analysis of Fatty Liver in the Framingham Heart Study CohortELIZABETH SPELIOTES; Fiscal Year: 2007....
