Research Topics
Species | DANIEL HAL SOLOMONSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Publications
The use of glucocorticoids in rheumatoid arthritis--no 'rational' approach yetSonali P Desai
Brigham and Women s Hospital, Division of Rheumatology, Immunology, and Allergy, 75 Francis Street, Boston, MA 02115, USA
Arthritis Res Ther 12:127. 2010..The relationship between glucocorticoids and bone mineral density in rheumatoid arthritis is complex. Further study into the optimal dosing, timing and duration of glucocorticoid use in rheumatoid arthritis is necessary...- The validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28Masayo Sato
Division of Pharmacoepidemiology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
Arthritis Res Ther 8:R57. 2006..The RARBIS has both face and convergent validity for patients with RA and relevant subgroups and may have application for medical records studies in patients with RA... - Adherence to osteoporosis medications after patient and physician brief education: post hoc analysis of a randomized controlled trialAimee Der Huey Shu
Division of Pharmacoepidemiology, Brigham and Women s Hospital, MA 02115, USA
Am J Manag Care 15:417-24. 2009..To examine whether adherence to osteoporosis medications can be improved by educational interventions targeted at primary care physicians (PCPs) and patients... - Prescription opioid use among older adults with arthritis or low back painDaniel H Solomon
Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Ste, 3030, Boston, MA 02120, USA
Arthritis Rheum 55:35-41. 2006..To examine patterns of chronic opioid use in selected groups with arthritis and low back pain and compare them with patterns among persons with ischemic heart disease... - A randomized controlled trial of mailed osteoporosis education to older adultsD H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
Osteoporos Int 17:760-7. 2006..The setting was a large publicly funded state pharmacy benefits program. The patients were 31,715 Medicare beneficiaries from Pennsylvania who participated in a drug benefits program for low-to-moderate income elderly people... - Lipid levels and bone mineral densityDaniel H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
Am J Med 118:1414. 2005..The aim of this study was to examine the relationship between lipid levels and bone mineral density... - Compliance with osteoporosis medicationsDaniel H Solomon
Divisions of Pharmacoepidemiology, Brigham and Women s Hospital, Boston, MA 02120, USA
Arch Intern Med 165:2414-9. 2005..This study was undertaken to assess the level and determinants of compliance with drugs prescribed for osteoporosis... - Selective cyclooxygenase 2 inhibitors and cardiovascular eventsDaniel H Solomon
Division of Pharmacoepidemiology, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02120, USA
Arthritis Rheum 52:1968-78. 2005 - Osteoporosis action: design of the healthy bones project trialDaniel H Solomon
Division of Pharmacoepidemiology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA, USA
Contemp Clin Trials 26:78-94. 2005..All outcomes will be analyzed using random effects models accounting for clustering of subjects within physicians' practices... - Medication use patterns for osteoporosis: an assessment of guidelines, treatment rates, and quality improvement interventionsDaniel H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
Mayo Clin Proc 80:194-202. 2005..To assess current osteoporosis treatment guidelines, studies of osteoporosis treatment, and interventions to improve osteoporosis treatment... - Adherence with osteoporosis practice guidelines: a multilevel analysis of patient, physician, and practice setting characteristicsDaniel H Solomon
Division of Pharmacoepidemiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Am J Med 117:919-24. 2004..The diagnosis and treatment of patients at risk of fragility fractures is uncommon. We examined the patient, physician, and practice characteristics associated with adherence to local osteoporosis guidelines... - Explaining the cardiovascular risk associated with rheumatoid arthritis: traditional risk factors versus markers of rheumatoid arthritis severityDaniel H Solomon
Brigham and Women s Hospital, Boston Massachusetts 02115, USA
Ann Rheum Dis 69:1920-5. 2010..The authors examined the relative importance of traditional CV risk factors and RA markers in predicting CV events... - Cardiovascular outcomes in new users of coxibs and nonsteroidal antiinflammatory drugs: high-risk subgroups and time course of riskDaniel H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
Arthritis Rheum 54:1378-89. 2006..This study was undertaken to examine, in a large group of new users of coxibs and NSAIDs, the rate of cardiovascular events, their time course, and whether baseline cardiovascular risk modified the rate ratios (RRs) for future events... - Development of a preliminary index that predicts adverse events after total knee replacementDaniel H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
Arthritis Rheum 54:1536-42. 2006.... - Patterns of cardiovascular risk in rheumatoid arthritisD H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
Ann Rheum Dis 65:1608-12. 2006..This study investigated the relative risk of myocardial infarction, stroke and CVD mortality in adults with rheumatoid arthritis compared with adults without rheumatoid arthritis across age groups, sex and prior CVD event status... - Subgroup analyses to determine cardiovascular risk associated with nonsteroidal antiinflammatory drugs and coxibs in specific patient groupsDaniel H Solomon
Brigham and Women s Hospital, 1620 Tremont Street, Boston, MA 02120, USA
Arthritis Rheum 59:1097-104. 2008..There is substantial concern regarding the potential cardiovascular adverse effects of selective coxibs and nonselective NSAIDs, but many patients with arthritis experience important clinical benefits from these agents... - The risk of infection associated with tumor necrosis factor alpha antagonists: making sense of epidemiologic evidenceDaniel H Solomon
Brigham and Women's Hospital, Division of Rheumatology, Immunology and Allergy, and Harvard Medical School, Boston, Massachusetts 02115, USA
Arthritis Rheum 58:919-28. 2008 - Percutaneous vertebroplasty among low income Medicare beneficiariesDaniel H Solomon
Divisions of Pharmacoepidemiology, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
Spine (Phila Pa 1976) 32:2910-4. 2007..Cohort... - Quality Measures 101: what every rheumatologist should knowD H Solomon
Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital, Boston, MA 02115, USA
Clin Exp Rheumatol 25:18-21. 2007..issues: why should rheumatology focus on quality measures now? how can rheumatology construct and assess quality measures? what can rheumatologists expect to achieve with quality measures? will quality measures be used for reimbursement?.. - Uric acid lowering therapy: prescribing patterns in a large cohort of older adultsD H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
Ann Rheum Dis 67:609-13. 2008..Uric acid lowering therapy (UALT) is considered a chronic treatment for gout. Relatively little is known about adherence to UALT... - Osteoporosis improvement: a large-scale randomized controlled trial of patient and primary care physician educationDaniel H Solomon
Division of Pharmacoepidemiology, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
J Bone Miner Res 22:1808-15. 2007..04; 95% ci, 0.85-1.26)... - Improving care of patients at-risk for osteoporosis: a randomized controlled trialDaniel H Solomon
Division of Pharmacepidemiology, Brigham and Women s Hospital, Boston, MA 02120, USA
J Gen Intern Med 22:362-7. 2007..We tested the effectiveness of an intervention to improve care in patients at-risk of osteoporosis... - Agreement between patient report and medical record review for medications used for rheumatoid arthritis: the accuracy of self-reported medication information in patient registriesDaniel H Solomon
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Arthritis Rheum 57:234-9. 2007..With the growth in patient registries in rheumatic disease research, it is important to validate the collected information. We examined the convergent validity of self-reported medication use for rheumatoid arthritis (RA)... - Osteoporosis management in patients with rheumatoid arthritis: Evidence for improvementDaniel H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Arthritis Rheum 55:873-7. 2006..The goal was to examine the frequency of osteoporosis management in patients with RA treated at a large academic rheumatology practice... - Immunosuppressive medications and hospitalization for cardiovascular events in patients with rheumatoid arthritisDaniel H Solomon
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Arthritis Rheum 54:3790-8. 2006..This study was undertaken to investigate the effects of various immunosuppressive medications on the risk of cardiovascular events among a group of older patients with RA... - Access to bone mineral density testing in patients at risk for osteoporosisD H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
Osteoporos Int 17:1749-54. 2006..We assessed whether access to bone mineral density (BMD) testing was a predictor of osteoporosis management in an at-risk population of patients from New Jersey... - Cardiovascular risk factors in women with and without rheumatoid arthritisDaniel H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Boston, MA 02120, USA
Arthritis Rheum 50:3444-9. 2004..The risk of cardiovascular disease (CVD) is increased in patients with rheumatoid arthritis (RA). The objective of this study was to examine the distribution of known CVD risk factors and biomarkers of CVD in women with and without RA... - Academic detailing to improve use of broad-spectrum antibiotics at an academic medical centerD H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 221 Longwood Ave, Suite 341, Boston, MA 02115, USA
Arch Intern Med 161:1897-902. 2001..We tested the efficacy of a targeted one-on-one educational program ("academic detailing") designed to improve the appropriateness of broad-spectrum antibiotic use... - Factors related to the use of bone densitometry: survey responses of 494 primary care physicians in New EnglandD H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 221 Longwood Avenue, Suite 341, Boston, MA 02115, USA
Osteoporos Int 14:123-9. 2003..Educational strategies aimed at improving the use of bone density testing should consider these factors... - Trends in knee magnetic resonance imagingDaniel H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Med Care 41:687-92. 2003..To assess trends in knee magnetic resonance imaging (MRI) use and accompanying management changes to determine whether indications for this test have changed over time... - The hidden cost of nonselective nonsteroidal antiinflammatory drugs in older patientsDaniel H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Rheumatol 30:792-8. 2003..We calculated the excess risk and costs associated with the major adverse effects of prescription nonselective NSAID... - Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritisDaniel H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
Circulation 107:1303-7. 2003..Rheumatoid arthritis may be associated with an increased risk of cardiovascular disease. We compared the incidence rates of myocardial infarction and stroke in subjects with and without rheumatoid arthritis... - Pharmacoepidemiology and rheumatic diseases: 2001-2002Daniel H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Curr Opin Rheumatol 15:122-6. 2003.... - Referrals for musculoskeletal disorders: patterns, predictors, and outcomesD H Solomon
Robert B Brigham Multipurpose Arthritis and Musculoskeletal Diseases Center, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
J Rheumatol 28:2090-5. 2001..To examine factors associated with musculoskeletal referral and determine whether referral influences clinical outcomes... - Management of glucocorticoid-induced osteoporosis in patients with rheumatoid arthritis: rates and predictors of care in an academic rheumatology practiceDaniel H Solomon
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Arthritis Rheum 46:3136-42. 2002..To examine rheumatologists' management practices for patients with rheumatoid arthritis (RA) taking glucocorticoids seen at one academic medical rheumatology practice... - Contribution of hospital characteristics to the volume-outcome relationship: dislocation and infection following total hip replacement surgeryDaniel H Solomon
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Arthritis Rheum 46:2436-44. 2002..We evaluated the contribution of hospital structural characteristics to the volume-outcome relationship in THR by examining the rates and predictors of postoperative complications... - Evidence-based guidelines for the use of immunologic tests: antinuclear antibody testingDaniel H Solomon
Division of Pharmacoepidemiology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
Arthritis Rheum 47:434-44. 2002 - Nonsteroidal anti-inflammatory drug use and acute myocardial infarctionDaniel H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Arch Intern Med 162:1099-104. 2002..Although aspirin has been shown to protect patients from acute myocardial infarction (AMI), the effect of nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs) is not clear... - Does self-management education benefit all populations with arthritis? A randomized controlled trial in a primary care physician networkDaniel H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Rheumatol 29:362-8. 2002..We conducted a randomized controlled trial of the ASMP course in a large primary care physician network... - Which patients with unstable angina or non-Q-wave myocardial infarction should have immediate cardiac catheterization? A clinical decision rule for predicting who will fail medical therapyDaniel H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, 221 Longwood Avenue, Suite 341, Boston, MA 02115, USA
J Clin Epidemiol 55:121-8. 2002..Such a rule may be useful for identifying patients who should be considered for early cardiac catheterization... - Underuse of osteoporosis medications in elderly patients with fracturesDaniel H Solomon
Division of Pharmacoepidemiology, Brigham and Women's Hospital, Boston, Massachusetts 02120, USA
Am J Med 115:398-400. 2003 - Relationship between COX-2 specific inhibitors and hypertensionDaniel H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02120, USA
Hypertension 44:140-5. 2004..1; 95% CI, 1.0 to 4.3). In this retrospective case-control study of patients aged > or =65 years, rofecoxib use was associated with an increased relative risk of new onset hypertension; this was not seen in patients taking celecoxib... - Multifaceted intervention to improve rheumatologists' management of glucocorticoid-induced osteoporosis: a randomized controlled trialDaniel H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Arthritis Rheum 51:383-7. 2004..To assess the effectiveness of a multifaceted intervention to improve the management of glucocorticoid-induced osteoporosis (GIOP)... - Relationship between selective cyclooxygenase-2 inhibitors and acute myocardial infarction in older adultsDaniel H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont St, Suite 3030, Boston, Mass 02120, USA
Circulation 109:2068-73. 2004..We studied the relative risk of acute myocardial infarction (AMI) among users of celecoxib, rofecoxib, and NSAIDs in Medicare beneficiaries with a comprehensive drug benefit... - Statin lipid-lowering drugs and bone mineral densityDaniel H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Boston, MA 02120, USA
Pharmacoepidemiol Drug Saf 14:219-26. 2005..We examined the relationship between statin use and bone density among postmenopausal women... - Which patients with knee problems are likely to benefit from nonarthroplasty surgery? Development of a clinical prediction ruleDaniel H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Arch Intern Med 164:509-13. 2004..We examined factors associated with the clinical presentation of patients judged likely by orthopedic surgeons to benefit from nonarthroplasty knee surgery... - Determinants of selective cyclooxygenase-2 inhibitor prescribing: are patient or physician characteristics more important?Daniel H Solomon
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Am J Med 115:715-20. 2003..We examined the relative effects of patient risk factors for gastrointestinal toxicity, other patient characteristics, and physician prescribing preferences on the decision to prescribe a selective COX-2 inhibitor... - Performance of a rheumatoid arthritis records-based index of severityGladys Ting
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
J Rheumatol 32:1679-87. 2005..Further tests of the RARBIS are recommended before it can be used as a tool to adjust for RA disease severity in performing epidemiologic studies on the safety of drugs... - Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective cyclooxygenase 2 inhibitors and nonselective nonsteroidal antiinflammatory drugs: an instrumental variable analysisSebastian Schneeweiss
Harvard Medical School, Division of Pharmacoepidemiology and Pharmacoeconomics, Boston, MA 021205, USA
Arthritis Rheum 54:3390-8. 2006.... - Anti-tumor necrosis factor alpha therapy and the risk of serious bacterial infections in elderly patients with rheumatoid arthritisSebastian Schneeweiss
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Arthritis Rheum 56:1754-64. 2007..To assess the association between the initiation of anti-tumor necrosis factor alpha (anti-TNFalpha) therapy and the risk of serious bacterial infections in routine care... - Accuracy of Medicare claims-based diagnosis of acute myocardial infarction: estimating positive predictive value on the basis of review of hospital recordsYuka Kiyota
Division of Pharmacoepidemiology and Pharmacoeconomics, Boston, Mass USA
Am Heart J 148:99-104. 2004..1% vs 94.6%, P <.001). CONCLUSIONS: In this study, we observed high positive predictive values for a Medicare claims-based diagnosis of AMI and a diagnosis based on structured hospital record review... - The medical license number accurately identifies the prescribing physician in a large pharmacy claims databaseM Alan Brookhart
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Med Care 45:907-10. 2007..We studied the accuracy of the medical license number in data from a state-run drug benefit plan by assessing its consistency with 2 external sources of data... - Predictors of discontinuation of tumor necrosis factor inhibitors in patients with rheumatoid arthritisSandeep K Agarwal
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Rheumatol 35:1737-44. 2008..Our goal was to determine the discontinuation rate of TNF inhibitors and identify predictors associated with discontinuation... - Adherence to lipid-lowering therapy and the use of preventive health services: an investigation of the healthy user effectM Alan Brookhart
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital Harvard Medical School, Boston, MA 02120, USA
Am J Epidemiol 166:348-54. 2007..Further work is needed to identify study design and analysis methods that can be used to minimize the healthy user bias in studies of preventive therapies... - Economic consequences of routine coronary angiography in low- and intermediate-risk patients with unstable angina pectorisAkshay S Desai
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Am J Cardiol 92:363-7. 2003.... - A Medicare database review found that physician preferences increasingly outweighed patient characteristics as determinants of first-time prescriptions for COX-2 inhibitorsSebastian Schneeweiss
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
J Clin Epidemiol 58:98-102. 2005..We sought to quantify the relative contributions of patient vs. physician factors to the decision to prescribe selective cyclooxygenase-2 (COX-2) inhibitors during the first 2 years of their availability... - Explained variation in a model of therapeutic decision making is partitioned across patient, physician, and clinic factorsM Alan Brookhart
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
J Clin Epidemiol 59:18-25. 2006..A statistical method is presented for attributing explained variation in patient care to different levels of aggregation in a multilevel model with the aim of prioritizing and targeting quality improvement interventions... - Relative effectiveness of osteoporosis drugs for preventing nonvertebral fractureSuzanne M Cadarette
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, and Boston University, Boston, Massachusetts 02120, USA
Ann Intern Med 148:637-46. 2008..Little information is available on the comparative effectiveness of osteoporosis pharmacotherapies... - Confounder summary scores when comparing the effects of multiple drug exposuresSuzanne M Cadarette
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Pharmacoepidemiol Drug Saf 19:2-9. 2010..We compared three analytic strategies to control for confounding based on measured variables: conventional multivariable, exposure propensity score (EPS), and disease risk score (DRS)... - Self-management education programs in chronic disease: a systematic review and methodological critique of the literatureAsra Warsi
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02120, USA
Arch Intern Med 164:1641-9. 2004..In light of evidence of publication bias, further trials that adhere to a standard methodology would help clarify whether self-management education is worthwhile... - Adjusting for unmeasured confounders in pharmacoepidemiologic claims data using external information: the example of COX2 inhibitors and myocardial infarctionSebastian Schneeweiss
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Epidemiology 16:17-24. 2005..We show how to assess the impact of confounding by factors not measured in Medicare claims data in a study of the association between selective COX2 inhibitors and acute myocardial infarction (MI)... - Veteran's affairs hospital discharge databases coded serious bacterial infections accuratelySebastian Schneeweiss
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
J Clin Epidemiol 60:397-409. 2007..We sought to test the ability of large health care utilization databases to accurately identify serious bacterial infections and opportunistic infections leading to hospital admission... - Evaluating short-term drug effects using a physician-specific prescribing preference as an instrumental variableM Alan Brookhart
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital Harvard Medical School, Boston, MA 02120, USA
Epidemiology 17:268-75. 2006..Instrumental variable methods have been proposed as a potential approach to control confounding by indication in nonexperimental studies of treatment effects; however, good instruments are hard to find... - A SAS macro for a clustered permutation testMargaret R Stedman
Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States
Comput Methods Programs Biomed 95:89-94. 2009..We describe a flexible and efficient SAS macro that implements the 2-sample clustered permutation test. We discuss the theory and applications behind this test as well as details of the SAS code... - The comparative safety of analgesics in older adults with arthritisDaniel H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, Boston, MA 02115, USA
Arch Intern Med 170:1968-76. 2010..The safety of alternative analgesics is unclear. We examined the comparative safety of nonselective NSAIDs (nsNSAIDs), selective cyclooxygenase 2 inhibitors (coxibs), and opioids... - A cohort study of thiazolidinediones and fractures in older adults with diabetesDaniel H Solomon
Division of Rheumatology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
J Clin Endocrinol Metab 94:2792-8. 2009..Recent results from several randomized controlled trials find an increased risk of fracture with TZDs compared with other oral antidiabetic agents... - Identification of individuals with CKD from Medicare claims data: a validation studyWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Am J Kidney Dis 46:225-32. 2005..The validity of this approach to identify patients with CKD has not been sufficiently studied... - Kidney function and use of recommended medications after myocardial infarction in elderly patientsWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
Clin J Am Soc Nephrol 1:796-801. 2006..Differences in other characteristics such as age, rather than kidney function, may be responsible for much or all the reported reduction in use of preventive medications after MI seen in patients with chronic kidney disease... - The relationship between focal erosions and generalized osteoporosis in postmenopausal women with rheumatoid arthritisDaniel H Solomon
Brigham and Women s Hospital, Division of Rheumatology, Boston, Massachusetts 02115, USA
Arthritis Rheum 60:1624-31. 2009..The aim of this study was to determine whether lower BMD is associated with higher erosion scores among patients with RA... - Physician follow-up and provider continuity are associated with long-term medication adherence: a study of the dynamics of statin useM Alan Brookhart
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
Arch Intern Med 167:847-52. 2007.... - The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: a cross-sectional studyYvonne C Lee
Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, 75 Francis Street, PBB B3, Boston, MA 02115, USA
Arthritis Res Ther 11:R160. 2009..The etiology of RA pain is likely multifactorial, including both inflammatory and non-inflammatory components. In this study, we examine the association between disease activity, sleep, psychiatric distress and pain sensitivity in RA... - Using genetic and clinical data to understand response to disease-modifying anti-rheumatic drug therapy: data from the Brigham and Women's Hospital Rheumatoid Arthritis Sequential StudyChristine K Iannaccone
Department of Medicine, Brigham and Women s Hospital, PBB B3, 75 Francis Street, Boston, MA 02115, USA
Rheumatology (Oxford) 50:40-6. 2011.... - Bisphosphonates and risk of atrial fibrillation: a meta-analysisSeo Young Kim
Division of Rheumatology, Allergy and Immunology, Department of Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA, 02115, USA
Arthritis Res Ther 12:R30. 2010.... - Tumor necrosis factor blockade and the risk of viral infectionSeo Young Kim
Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Nat Rev Rheumatol 6:165-74. 2010..In addition, implications for clinical practice and possible preventative approaches are discussed... - An evaluation of the relationship between the implementation of a newly designed prescription drug label at Target pharmacies and health outcomesWilliam H Shrank
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Med Care 47:1031-5. 2009..A new prescription medication labeling system was implemented by Target pharmacies in May 2005 and aimed to improve health outcomes... - High-risk patients' readiness to undergo BMD testing for osteoporosis diagnosis in PennsylvaniaJennifer M Polinski
Brigham and Women s Hospital, Boston, Massachusetts, USA
Int Q Community Health Educ 29:223-40. 2008..We found several correlates of readiness to undergo BMD screening that may be used to design effective interventions... - Osteoporosis medication use in nursing home patients with fractures in 1 US stateSeema Parikh
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02120, USA
Arch Intern Med 168:1111-5. 2008..We studied the patterns and predictors of osteoporosis medication use in elderly patients who sustained a fracture and were admitted to an NH... - Hand bone mineral density is associated with both total hip and lumbar spine bone mineral density in post-menopausal women with RASonali P Desai
Brigham and Women s Hospital, PBB B3, Boston, MA 02115, USA
Rheumatology (Oxford) 49:513-9. 2010..RA is associated with localized bone loss in the hands, as well as generalized osteoporosis. We evaluated the relationship between hand digital X-ray radiogrammetry BMD (DXR-BMD) and total hip and lumbar spine BMD... - Alcohol consumption and markers of inflammation in women with preclinical rheumatoid arthritisBing Lu
Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Arthritis Rheum 62:3554-9. 2010..To examine the association between alcohol consumption and markers of inflammation in preclinical rheumatoid arthritis (RA)... - Cost-effectiveness of total knee arthroplasty in the United States: patient risk and hospital volumeElena Losina
Department of Orthopedic Surgery, Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women s Hospital, Boston, MA 02115, USA
Arch Intern Med 169:1113-21; discussion 1121-2. 2009..However, to our knowledge, the cost-effectiveness of TKA and the influences of hospital volume and patient risk on TKA cost-effectiveness have not been investigated in the United States... - Pharmacological management of osteoporosis in nursing home populations: a systematic reviewSeema Parikh
Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts, USA
J Am Geriatr Soc 57:327-34. 2009..Prescribing for elderly NH patients is difficult, considering the risk:benefit ratio and issues of longevity, but these medications may be underused in the NH environment... - Conversion from intravenous to oral medications: assessment of a computerized intervention for hospitalized patientsMichael A Fischer
Division of Pharmacoepidemiology and Pharmacoeconomics, Departments of Medicine and Emergency Medicine, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
Arch Intern Med 163:2585-9. 2003..We examined the effect of a computer-based intervention to prompt physicians to switch appropriate patients from intravenous to oral medications... - Cardiovascular care and cancer screening in female nurses with and without rheumatoid arthritisDaniel H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Arthritis Rheum 51:429-32. 2004..To compare frequencies of cancer screening and cardiovascular treatments aimed at reducing acute myocardial infarction in women with and without rheumatoid arthritis (RA)... - Medicaid prior-authorization programs and the use of cyclooxygenase-2 inhibitorsMichael A Fischer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
N Engl J Med 351:2187-94. 2004..To control these expenses, many state Medicaid programs have implemented prior-authorization requirements before coxibs can be prescribed. We evaluated the effect of such programs on the use of coxibs by Medicaid beneficiaries... - Agreement of diagnosis and its date for hematologic malignancies and solid tumors between medicare claims and cancer registry dataSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Cancer Causes Control 18:561-9. 2007..However, linkage between cancer registry and claims data including pharmacy-dispensing information is not always available. We examined the accuracy of claims-based definitions of incident cancers and their date of diagnosis... - Prior authorization policies for selective cyclooxygenase-2 inhibitors in Medicaid: a policy reviewMichael A Fischer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Boston, MA 02120, USA
Med Care 44:658-63. 2006..However, the evidence base for the prior authorization criteria has not been examined previously... - Prior authorization for biologic disease-modifying antirheumatic drugs: a description of US Medicaid programsMichael A Fischer
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Arthritis Rheum 59:1611-7. 2008..To evaluate state Medicaid prior authorization programs for biologic disease-modifying antirheumatic drugs (DMARDs)... - Nonselective and cyclooxygenase-2-selective NSAIDs and acute kidney injuryWolfgang C Winkelmayer
The Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Am J Med 121:1092-8. 2008..We undertook a large pharmacoepidemiologic analysis of the risk of acute kidney injury among older adults using nonselective NSAIDs or cyclooxygenase (COX)-2 inhibitors... - Rates and determinants of reinitiating antihypertensive therapy after prolonged stoppage: a population-based studyBoris L G Van Wijk
Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
J Hypertens 25:689-97. 2007..To assess patterns of restarting antihypertensive drugs after a prolonged period of discontinuation... - The patient's perspective on the recall of VioxxGillian A Hawker
Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
J Rheumatol 33:1082-8. 2006..Rofecoxib was recalled in September 2004 when studies identified increased cardiovascular risk compared with placebo among patients taking rofecoxib. We examined the reactions of people with arthritis to this recall... - Treatment of older adult patients diagnosed with rheumatoid arthritis: improved but not optimalGabriela Schmajuk
Stanford University, Palo Alto, California, USA
Arthritis Rheum 57:928-34. 2007..Our objective was to determine the rate and predictors of DMARD use in a cohort of elderly patients with RA... - COX-2 selective non-steroidal anti-inflammatory drugs and cardiovascular diseaseWayne A Ray
Vanderbilt University School of Medicine, A-1124, MCN, Nashville, TN 37232, USA
Pharmacoepidemiol Drug Saf 12:67-70. 2003 - Generalist, specialist, or both?Daniel H Solomon
J Rheumatol 29:1345-7. 2002
Research Grants
- Osteoporosis in Women with Rheumatoid ArthritisDaniel Solomon; Fiscal Year: 2006..This epidemiologic data will inform future trials of osteoporosis treatments among patients with RA. As well, the study cohort will comprise one of the largest RA registries with an explicit plan to examine osteoporosis. ..
- Randomized Controlled Testing of Osteoporosis EducationDaniel Solomon; Fiscal Year: 2006..A multi-disciplinary Training Advisory Board will review the applicants progress regularly to ensure that the proposed training goals are met. ..
- Pain Medication Use & Risk Factors for Opioid DependenceDaniel Solomon; Fiscal Year: 2004..Our goal is to use the results of the proposed research to inform a future intervention to improve opioid prescribing within this large pharmacy benefits program. ..
- Why is Cardiac Risk Increased in Rheumatiod ArthritisDaniel Solomon; Fiscal Year: 2002..ability to control for known cardiovascular risk factors, the extensive medication information allowing for us to explore key hypotheses regarding corticosteroid exposure, and the attempt to simultaneously control for disease severity ..
- Modifiable Disparities in Treatment for Rheumatoid ArthritisDANIEL HAL SOLOMON; Fiscal Year: 2010..As well, by focusing on potentially modifiable risk factors, the information collected will point directly toward strategies for reducing disparities in DMARD use. ..