Barbara L Smith

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi request reprint Clinical applications of breast pathology: management of in situ breast carcinomas and sentinel node biopsy issues
    Barbara L Smith
    Massachusetts General Hospital, Gillette Center for Women s Cancers, Boston, MA, USA
    Mod Pathol 23:S33-5. 2010
  2. ncbi request reprint Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ
    Francisco J Dominguez
    Division of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Ann Surg Oncol 15:268-73. 2008
  3. doi request reprint The association between biological subtype and isolated regional nodal failure after breast-conserving therapy
    Jennifer Y Wo
    Harvard Radiation Oncology Program, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 77:188-96. 2010
  4. doi request reprint Residual lymph node disease after neoadjuvant chemotherapy predicts an increased risk of lymphedema in node-positive breast cancer patients
    Michelle C Specht
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, MA, USA
    Ann Surg Oncol 20:2835-41. 2013
  5. doi request reprint Nomogram for the prediction of having four or more involved nodes for sentinel lymph node-positive breast cancer
    Angela Katz
    Department of Radiation Oncology, Massachusetts General Hospital, 100 Blossom St, Cox 301, Boston, MA 02114, USA
    J Clin Oncol 26:2093-8. 2008
  6. ncbi request reprint Evaluation of hereditary risk in a mammography population
    Julie L Jones
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Breast Cancer 6:38-44. 2005
  7. doi request reprint Application of ACOSOG Z0011 criteria reduces perioperative costs
    Melissa S Camp
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, MA, USA
    Ann Surg Oncol 20:836-41. 2013
  8. doi request reprint Do sentinel node micrometastases predict recurrence risk in ductal carcinoma in situ and ductal carcinoma in situ with microinvasion?
    Colleen D Murphy
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, MA, USA
    Am J Surg 196:566-8. 2008
  9. pmc Accelerated partial breast irradiation with low-dose-rate interstitial implant brachytherapy after wide local excision: 12-year outcomes from a prospective trial
    Jona A Hattangadi
    Harvard Radiation Oncology Program, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 83:791-800. 2012
  10. doi request reprint Outcome of multiple-wire localization for larger breast cancers: do multiple wires translate into additional imaging, biopsies, and recurrences?
    Sara H Javid
    Department of Surgery, Division of Surgical Oncology, Boston, MA 02114, USA
    Am J Surg 198:368-72. 2009

Detail Information

Publications71

  1. doi request reprint Clinical applications of breast pathology: management of in situ breast carcinomas and sentinel node biopsy issues
    Barbara L Smith
    Massachusetts General Hospital, Gillette Center for Women s Cancers, Boston, MA, USA
    Mod Pathol 23:S33-5. 2010
    ....
  2. ncbi request reprint Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ
    Francisco J Dominguez
    Division of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Ann Surg Oncol 15:268-73. 2008
    ..There is uncertainty about the utility of sentinel node biopsy (SNB) for ductal carcinoma in situ (DCIS) and its potential to avoid axillary lymph node dissection (ALND) in patients undergoing mastectomy for DCIS...
  3. doi request reprint The association between biological subtype and isolated regional nodal failure after breast-conserving therapy
    Jennifer Y Wo
    Harvard Radiation Oncology Program, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 77:188-96. 2010
    ....
  4. doi request reprint Residual lymph node disease after neoadjuvant chemotherapy predicts an increased risk of lymphedema in node-positive breast cancer patients
    Michelle C Specht
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, MA, USA
    Ann Surg Oncol 20:2835-41. 2013
    ..We sought to determine if neoadjuvant chemotherapy reduced the risk of lymphedema in patients undergoing ALND for node-positive breast cancer...
  5. doi request reprint Nomogram for the prediction of having four or more involved nodes for sentinel lymph node-positive breast cancer
    Angela Katz
    Department of Radiation Oncology, Massachusetts General Hospital, 100 Blossom St, Cox 301, Boston, MA 02114, USA
    J Clin Oncol 26:2093-8. 2008
    ..The purpose of this study was to define possible predictors of having four or more involved nodes to provide information for clinicians and patients making decisions about adjuvant chemotherapy and radiation...
  6. ncbi request reprint Evaluation of hereditary risk in a mammography population
    Julie L Jones
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Clin Breast Cancer 6:38-44. 2005
    ..We then applied current risk-assessment models to determine the prevalence of women at risk for hereditary breast and ovarian cancer...
  7. doi request reprint Application of ACOSOG Z0011 criteria reduces perioperative costs
    Melissa S Camp
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, MA, USA
    Ann Surg Oncol 20:836-41. 2013
    ..We determined whether application of Z0011 guidelines would reduce costs...
  8. doi request reprint Do sentinel node micrometastases predict recurrence risk in ductal carcinoma in situ and ductal carcinoma in situ with microinvasion?
    Colleen D Murphy
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, MA, USA
    Am J Surg 196:566-8. 2008
    ....
  9. pmc Accelerated partial breast irradiation with low-dose-rate interstitial implant brachytherapy after wide local excision: 12-year outcomes from a prospective trial
    Jona A Hattangadi
    Harvard Radiation Oncology Program, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 83:791-800. 2012
    ..To evaluate the long-term toxicity, cosmesis, and local control of accelerated partial breast irradiation with implant brachytherapy after wide local excision for Stage T1N0 breast cancer (BCa)...
  10. doi request reprint Outcome of multiple-wire localization for larger breast cancers: do multiple wires translate into additional imaging, biopsies, and recurrences?
    Sara H Javid
    Department of Surgery, Division of Surgical Oncology, Boston, MA 02114, USA
    Am J Surg 198:368-72. 2009
    ..Breast conservation is possible in breast cancer patients whose mammographic lesions are large enough to require multiple localizing wires for excision...
  11. doi request reprint Outcomes of multiple wire localization for larger breast cancers: when can mastectomy be avoided?
    Laurie J Kirstein
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, MA 02115, USA
    J Am Coll Surg 207:342-6. 2008
    ..We also wanted to identify factors that predicted a poor chance of successful lumpectomy, to avoid multiple lumpectomy attempts in a patient who would ultimately require mastectomy...
  12. ncbi request reprint Breast cancer diagnosis in women < or = 40 versus 50 to 60 years: increasing size and stage disparity compared with older women over time
    Katherina Zabicki
    Department of Surgery, Division of Surgical Oncology, Massachusetts General Hospital Harvard Medical School, 55 Fruit Street, Yawkey 9, Boston, Massachusetts 02114, USA
    Ann Surg Oncol 13:1072-7. 2006
    ..Women < or = 40 years account for 5% of new breast cancer diagnoses. Although there is increased awareness of genetic and other breast cancer risk factors, it is not clear whether this has resulted in earlier diagnosis in young women...
  13. ncbi request reprint Prevalence of hereditary breast/ovarian carcinoma risk in patients with a personal history of breast or ovarian carcinoma in a mammography population
    Francisco J Dominguez
    Division of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Cancer 104:1849-53. 2005
    ..The authors sought to determine the prevalence of family histories suggestive of a hereditary breast carcinoma syndrome in a cohort of patients with a personal history of breast and/or ovarian carcinoma presenting for mammography...
  14. pmc Basal subtype of invasive breast cancer is associated with a higher risk of true recurrence after conventional breast-conserving therapy
    Jona A Hattangadi-Gluth
    Harvard Radiation Oncology Program, Boston, Massachusetts, USA
    Int J Radiat Oncol Biol Phys 82:1185-91. 2012
    ....
  15. doi request reprint Why cancer at the primary site and in the lymph nodes contributes to the risk of cancer death
    James S Michaelson
    Department of Pathology, Massachusetts General Hospital, Boston, Massachusett, USA
    Cancer 115:5084-94. 2009
    ....
  16. ncbi request reprint Long-term risk of false-positive screening results and subsequent biopsy as a function of mammography use
    Karen Blanchard
    Department of Surgery, Massachusetts General Hospital, Yawkey 7939, 55 Fruit St, Boston, MA 02114, USA
    Radiology 240:335-42. 2006
    ..To retrospectively determine the long-term risk of false-positive mammographic assessments and to evaluate the effect of screening regularity on the risk of false-positive events...
  17. pmc Sentinel lymph node biopsy at the time of mastectomy does not increase the risk of lymphedema: implications for prophylactic surgery
    Cynthia L Miller
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Breast Cancer Res Treat 135:781-9. 2012
    ..Addition of SLNB to mastectomy is not associated with a significant increase in measured or self-reported lymphedema rates. Therefore, SLNB may be performed at the time of prophylactic mastectomy without an increased risk of lymphedema...
  18. pmc Age, breast cancer subtype approximation, and local recurrence after breast-conserving therapy
    Nils D Arvold
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, MA 02215, USA
    J Clin Oncol 29:3885-91. 2011
    ..Prior results of breast-conserving therapy (BCT) have shown substantial rates of local recurrence (LR) in young patients with breast cancer (BC)...
  19. doi request reprint Breast surgery in stage IV breast cancer: impact of staging and patient selection on overall survival
    Andrea C Bafford
    Brigham and Women s Hospital, Boston, MA 02115, USA
    Breast Cancer Res Treat 115:7-12. 2009
    ..Retrospective analyses suggest patients with stage IV breast cancer who undergo breast surgery have improved survival. We sought to determine whether surgery and other clinical and staging factors affected overall survival...
  20. doi request reprint The American Cancer Society guidelines for breast screening with magnetic resonance imaging: an argument for genetic testing
    Colleen D Murphy
    Department of Surgery, Division of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Cancer 113:3116-20. 2008
    ....
  21. doi request reprint How cancer at the primary site and in the lymph nodes contributes to the risk of cancer death
    James S Michaelson
    Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Cancer 115:5095-107. 2009
    ....
  22. doi request reprint Tangential radiotherapy without axillary surgery in early-stage breast cancer: results of a prospective trial
    Julia S Wong
    Department of Radiation Oncology, Dana Farber Brigham and Women s Cancer Center, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 72:866-70. 2008
    ....
  23. ncbi request reprint Accelerated partial-breast irradiation using proton beams: initial clinical experience
    Kevin R Kozak
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Int J Radiat Oncol Biol Phys 66:691-8. 2006
    ..We present our initial clinical experience with proton, three-dimensional, conformal, external beam, partial-breast irradiation (3D-CPBI)...
  24. doi request reprint Cost comparison of radiation treatment options after lumpectomy for breast cancer
    Rachel A Greenup
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, MA, USA
    Ann Surg Oncol 19:3275-81. 2012
    ..Radiation therapy (RT) after lumpectomy for breast cancer can be delivered with several different regimens. We evaluated a cost-minimization strategy to select among RT options...
  25. doi request reprint Breast cancer subtype approximated by estrogen receptor, progesterone receptor, and HER-2 is associated with local and distant recurrence after breast-conserving therapy
    Paul L Nguyen
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA
    J Clin Oncol 26:2373-8. 2008
    ..To determine whether breast cancer subtype is associated with outcome after breast-conserving therapy (BCT) consisting of lumpectomy and radiation therapy...
  26. doi request reprint Occult nipple involvement in breast cancer: clinicopathologic findings in 316 consecutive mastectomy specimens
    Elena F Brachtel
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    J Clin Oncol 27:4948-54. 2009
    ..This study evaluates frequency and patterns of occult nipple involvement in a large contemporary cohort of patients with the retroareolar margin as possible indicator of nipple involvement...
  27. ncbi request reprint A comparison of sentinel node biopsy before and after neoadjuvant chemotherapy: timing is important
    Julie L Jones
    Department of Surgical Oncology, Massachusetts General Hospital, 55 Fruit St, Yawkey Building, 7th Floor, Boston, MA 02114, USA
    Am J Surg 190:517-20. 2005
    ..In this study, we compared the identification rates of SNB before and after neoadjuvant chemotherapy and evaluated the false-negative rate of SNB after chemotherapy...
  28. doi request reprint Risk of lymphedema after mastectomy: potential benefit of applying ACOSOG Z0011 protocol to mastectomy patients
    Cynthia L Miller
    Department of Radiation Oncology, Massachusetts General Hospital, 100 Blossom Street, Boston, MA, 02114, USA
    Breast Cancer Res Treat 144:71-7. 2014
    ..Future trials should investigate the safety of applying the ACOSOG Z0011 protocol to mastectomy patients. ..
  29. ncbi request reprint The age at which women begin mammographic screening
    James A Colbert
    Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Cancer 101:1850-9. 2004
    ..The American Cancer Society recommends yearly mammographic screening for women starting at the age of 40 years. The authors examined the age at which women began screening at a large tertiary care center...
  30. doi request reprint Proton therapy for breast cancer after mastectomy: early outcomes of a prospective clinical trial
    Shannon M Macdonald
    Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Int J Radiat Oncol Biol Phys 86:484-90. 2013
    ..We report acute toxicities and feasibility of proton delivery for 12 women treated with postmastectomy proton radiation with or without reconstruction...
  31. doi request reprint The role of chemoprevention in modifying the risk of breast cancer in women with atypical breast lesions
    Suzanne B Coopey
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, MA, USA
    Breast Cancer Res Treat 136:627-33. 2012
    ..05). The risk of breast cancer with atypical breast lesions is substantial. Physicians should counsel patients with ADH, ALH, LCIS, and severe ADH about the benefit of chemoprevention in decreasing their breast cancer risk...
  32. doi request reprint Current surgical approach to Paget's disease
    Laura S Dominici
    Department of Surgical Oncology, Brigham and Women s Hospital Dana Farber Cancer Institute, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    Am J Surg 204:18-22. 2012
    ..Paget's disease constitutes between 1% and 3% of all breast malignancies, which makes defining standard surgical therapy difficult. We sought to identify preoperative factors that would select patients for successful breast conservation...
  33. doi request reprint Tubular carcinoma of the breast: results of a large contemporary series
    Sara H Javid
    Department of Surgery, Brigham and Women s Hospital Dana Farber Cancer Institute, Boston, MA 02115, USA
    Am J Surg 197:674-7. 2009
    ..Tubular carcinoma (TC) of the breast is an uncommon subtype associated with a favorable prognosis. This study aimed to assess recent trends and prognostic features in the treatment of TC...
  34. ncbi request reprint Accuracy of self-reported personal history of cancer in an outpatient breast center
    Francisco J Dominguez
    Surgical Oncology Division, Massachusetts General Hospital, Harvard Medical School, 32 Fruit street YAW 7, Boston, Massachusetts, USA
    J Genet Couns 16:341-5. 2007
    ..008), and those with Jewish ancestry more accurately than non-Jewish (p=0.0435). These results will help us to improve data collection and thus improve medical decision-making...
  35. ncbi request reprint Case records of the Massachusetts General Hospital. Case 32-2007. A 62-year-old woman with a second breast cancer
    Eric P Winer
    Department of Medical Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, USA
    N Engl J Med 357:1640-8. 2007
  36. doi request reprint Eight-year update of a prospective study of wide excision alone for small low- or intermediate-grade ductal carcinoma in situ (DCIS)
    Julia S Wong
    Department of Radiation Oncology, Dana Farber Cancer Institute Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Breast Cancer Res Treat 143:343-50. 2014
    ..This information should be useful as patients and clinicians weigh the options of wide excision with and without radiation. ..
  37. pmc Lumpectomy plus tamoxifen with or without irradiation in women age 70 years or older with early breast cancer: long-term follow-up of CALGB 9343
    Kevin S Hughes
    Harvard Medical School, Boston, MA, USA
    J Clin Oncol 31:2382-7. 2013
    ..To determine whether there is a benefit to adjuvant radiation therapy after breast-conserving surgery and tamoxifen in women age ≥ 70 years with early-stage breast cancer...
  38. doi request reprint Increasing eligibility for nipple-sparing mastectomy
    Suzanne B Coopey
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, MA, USA
    Ann Surg Oncol 20:3218-22. 2013
    ..Eligibility for nipple-sparing mastectomy (NSM) varies widely on the basis of patient and tumor factors...
  39. doi request reprint Use of preoperative paravertebral block decreases length of stay in patients undergoing mastectomy plus immediate reconstruction
    Suzanne B Coopey
    Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Ann Surg Oncol 20:1282-6. 2013
    ..We sought to determine if the use of PVB in patients undergoing unilateral or bilateral mastectomy plus immediate reconstruction decreases patient LOS...
  40. doi request reprint Diagnosis of breast cancer in women age 40 and younger: delays in diagnosis result from underuse of genetic testing and breast imaging
    Srila Samphao
    Department of Surgery, Division of Surgical Oncology, Massachusetts General Hospital Harvard Medical School, Yawkey 9A, 55 Fruit St, Boston, MA 02114, USA
    Am J Surg 198:538-43. 2009
    ..The impact of newer breast imaging technologies and genetic testing on the detection of breast cancer in women age 40 and younger remains unknown...
  41. ncbi request reprint Tubular carcinoma of the breast: a retrospective analysis and review of the literature
    Timothy Sullivan
    Department of Radiation Oncology, Harvard Medical School, Boston, MA 02114, USA
    Breast Cancer Res Treat 93:199-205. 2005
    ..The favorable prognosis associated with tubular carcinoma of the breast has led some studies to propose less aggressive treatments for patients with this disease. This study aims to address the extent of therapy needed for tubular patients...
  42. ncbi request reprint Prospective study of wide excision alone for ductal carcinoma in situ of the breast
    Julia S Wong
    Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 24:1031-6. 2006
    ..It has been hypothesized that wide excision alone with margins > or = 1 cm may be adequate treatment for small, grade 1 or 2 ductal carcinoma in situ (DCIS). To test this hypothesis, we conducted a prospective, single-arm trial...
  43. doi request reprint Micro-computed tomography (Micro-CT): a novel approach for intraoperative breast cancer specimen imaging
    Rong Tang
    Division of Surgical Oncology, Gillette Center for Women s Cancers, Massachusetts General Hospital, Boston, MA 02114, USA
    Breast Cancer Res Treat 139:311-6. 2013
    ..Micro-CT may also be useful for assessing sentinel lymph nodes and mastectomy specimens...
  44. doi request reprint A pilot study evaluating shaved cavity margins with micro-computed tomography: a novel method for predicting lumpectomy margin status intraoperatively
    Rong Tang
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts Division of Breast Surgery, Hunan Provincial Tumor Hospital, The Affiliated Tumor Hospital of Xiangya Medical School of Central South University, China
    Breast J 19:485-9. 2013
    ..The scanning time required is short enough to permit real-time feedback to the operating surgeon, allowing immediate directed re-excision. ..
  45. doi request reprint Nipple-sparing mastectomy: lessons from ex vivo procedures
    Jennifer E Rusby
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Breast J 14:464-70. 2008
    ..When performing nipple-sparing mastectomy for breast cancer, these measures may be advisable as complements to careful patient selection...
  46. ncbi request reprint Sentinel lymph node biopsy in men with breast cancer: a report of 31 consecutive procedures and review of the literature
    Jennifer E Rusby
    Massachusetts General Hospital, Boston, MA, USA
    Clin Breast Cancer 7:406-10. 2006
    ..Consecutive men with breast cancer undergoing SLN biopsy were identified in our prospectively maintained database. A PubMed search for "male breast cancer" and "sentinel node biopsy" was performed...
  47. ncbi request reprint Initial dosimetric experience using simple three-dimensional conformal external-beam accelerated partial-breast irradiation
    Alphonse G Taghian
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Int J Radiat Oncol Biol Phys 64:1092-9. 2006
    ..Several accelerated partial-breast irradiation (APBI) techniques are being investigated in patients with early-stage breast cancer. We present our initial experience using three-dimensional conformal radiation therapy (3D-CRT)...
  48. ncbi request reprint Breast cancer treatment in older women
    Marissa Howard-McNatt
    Division of Surgical Oncology, Massachusetts General Hospital, 100 Blossom Street, Cox 626, Boston, MA 02114, USA
    Surg Oncol Clin N Am 14:85-102, vi. 2005
    ..There are controversies surrounding the management of breast cancer in this population regarding adjuvant therapy, radiation therapy and surgical options. We endeavor to address these issues in the article...
  49. pmc Defining a threshold for intervention in breast cancer-related lymphedema: what level of arm volume increase predicts progression?
    Michelle C Specht
    Division of Surgical Oncology, Massachusetts General Hospital, 100 Blossom Street, Boston, MA 02114, USA
    Breast Cancer Res Treat 140:485-94. 2013
    ..Additional risk factors for progression to ≥10 % include ALND, higher BMI, and post-operative arm volume elevation. ..
  50. doi request reprint The safety of multiple re-excisions after lumpectomy for breast cancer
    Suzanne Coopey
    Department of Surgical Oncology, Massachusetts General Hospital, Boston, MA, USA
    Ann Surg Oncol 18:3797-801. 2011
    ..We sought to determine the overall local recurrence rate and surgical outcome of patients undergoing two or more re-excisions and to identify predictors of success in attaining clear margins...
  51. ncbi request reprint George Peters Award. Microscopic anatomy within the nipple: implications for nipple-sparing mastectomy
    Jennifer E Rusby
    Division of Surgical Oncology, Yawkey 9A, Massachusetts General Hospital, Fruit St, Boston, MA 02114, USA
    Am J Surg 194:433-7. 2007
    ..Precise anatomical relationships between ducts and vasculature within the nipple remain unknown. This study investigated nipple microvessels and their position relative to ducts...
  52. ncbi request reprint Breast conservation for male breast carcinoma
    Mehra Golshan
    Department of Surgery, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Breast 16:653-6. 2007
    ..Breast-conserving surgery in male breast cancer patients should be considered an option in patients without overt nipple/areolar involvement...
  53. ncbi request reprint Surgical treatment options in young women with breast cancer
    Dalliah Black
    Division of Surgical Oncology, Massachusetts General Hospital, Boston, 02114, USA
    Breast Dis 23:37-45. 2005
    ..Management of young women with BRCA gene mutations, with a positive family history without a risk gene mutation, and with a history of mantle irradiation for Hodgkin's disease is discussed...
  54. doi request reprint Mucinous breast carcinoma: a large contemporary series
    Christina R Barkley
    Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    Am J Surg 196:549-51. 2008
    ..Mucinous breast cancer is typically associated with a favorable prognosis. This study aimed to assess recent trends and prognostic features in the treatment of mucinous breast carcinoma...
  55. doi request reprint The impact of primary tumor size, lymph node status, and other prognostic factors on the risk of cancer death
    L Leon Chen
    Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA
    Cancer 115:5071-83. 2009
    ..There is currently no method for integrating tumor size, lymph node status, and other prognostic information from a patient into a single risk of death estimate...
  56. doi request reprint Lumpectomy cavity shaved margins do not impact re-excision rates in breast cancer patients
    Suzanne B Coopey
    Surgical Oncology, Massachusetts General Hospital, Boston, MA, USA
    Ann Surg Oncol 18:3036-40. 2011
    ..The benefits of taking shaved cavity margins (SCM) at the time of lumpectomy are unclear. We sought to determine if taking SCM decreases re-excision rates by increasing the total breast tissue volume excised...
  57. ncbi request reprint Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer
    Kevin S Hughes
    Avon Comprehensive Breast Evaluation Center, Breast Ovarian Cancer Genetics and Risk Assessment Program, Massachusetts General Hospital, Division of Surgical Oncology, Boston 02114, USA
    N Engl J Med 351:971-7. 2004
    ..In women 70 years of age or older who have early breast cancer, it is unclear whether lumpectomy plus tamoxifen is as effective as lumpectomy followed by tamoxifen plus radiation therapy...
  58. doi request reprint Breast Reconstruction following Nipple-Sparing Mastectomy: Predictors of Complications, Reconstruction Outcomes, and 5-Year Trends
    Amy S Colwell
    Boston, Mass From the Division of Plastic Surgery, Massachusetts General Hospital, Harvard Medical School
    Plast Reconstr Surg 133:496-506. 2014
    ..Nipple-sparing mastectomy is increasingly used for treatment and prevention of breast cancer. Few data exist on risk factors for complications and reconstruction outcomes...
  59. pmc External beam accelerated partial-breast irradiation using 32 gy in 8 twice-daily fractions: 5-year results of a prospective study
    Itai M Pashtan
    Harvard Radiation Oncology Program, Boston, Massachusetts, USA
    Int J Radiat Oncol Biol Phys 84:e271-7. 2012
    ..Here we present 5-year results of a prospective trial...
  60. pmc Standardized method for quantification of developing lymphedema in patients treated for breast cancer
    Marek Ancukiewicz
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Int J Radiat Oncol Biol Phys 79:1436-43. 2011
    ..To develop a simple and practical formula for quantifying breast cancer-related lymphedema, accounting for both the asymmetry of upper extremities' volumes and their temporal changes...
  61. pmc The feasibility of using natural language processing to extract clinical information from breast pathology reports
    Julliette M Buckley
    Department of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA
    J Pathol Inform 3:23. 2012
    ..The variety of ways in which each diagnosis could be represented was recorded, as a means of demonstrating the complexity of machine interpretation of free text...
  62. doi request reprint An inferolateral approach to nipple-sparing mastectomy: optimizing mastectomy and reconstruction
    Amy S Colwell
    Mass General Hospital, Boston, MA 02114, USA
    Ann Plast Surg 65:140-3. 2010
    ..The incision allows adequate access and hides the scar on anterior view, thus optimizing both the mastectomy and reconstruction. In patients with a preexisting lateral scar, this may be the incision of choice...
  63. doi request reprint Neoadjuvant bevacizumab: surgical complications of mastectomy with and without reconstruction
    Kari Joanne Kansal
    Brigham and Women s Hopspital, Boston, MA, USA
    Breast Cancer Res Treat 141:255-9. 2013
    ..As larger data sets become available with the use of neoadjuvant bevacizumab with mastectomy, further refinement may be necessary. ..
  64. pmc Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
    Triantafyllos Stylianopoulos
    Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Proc Natl Acad Sci U S A 109:15101-8. 2012
    ..In addition to providing insights into the mechanopathology of tumors, our approach can serve as a rapid screen for stress-reducing and perfusion-enhancing drugs...
  65. doi request reprint A 16-year-old male with gynecomastia and ductal carcinoma in situ
    Henry L Chang
    Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Warren 1153, Boston, MA, USA
    Pediatr Surg Int 24:1251-3. 2008
    ..We present a 16-year-old male with unilateral gynecomastia discovered to have ductal carcinoma in situ (DCIS), treated by mastectomy with 4 year follow-up...
  66. ncbi request reprint Breast duct anatomy in the human nipple: three-dimensional patterns and clinical implications
    Jennifer E Rusby
    Gillette Center for Breast Cancer, Division of Surgical Oncology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Breast Cancer Res Treat 106:171-9. 2007
    ..There is variation in the number of ducts reported and little is known about the spatial location of ducts, their size, and their relationship to orifices on the surface...
  67. ncbi request reprint Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 28-2003. A 51-year-old premenopausal woman with newly diagnosed breast cancer and a strong family history of breast cancer
    Paula D Ryan
    Gillette Center for Women s Cancer, Massachusetts General Hospital, Boston, USA
    N Engl J Med 349:1076-82. 2003
  68. ncbi request reprint Dose-volume analysis of radiotherapy for T1N0 invasive breast cancer treated by local excision and partial breast irradiation by low-dose-rate interstitial implant
    Brian D Lawenda
    Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Int J Radiat Oncol Biol Phys 56:671-80. 2003
    ..Thus, the tolerance of escalating doses of partial breast RT should be determined, because this approach may become a standard treatment for patients with early-stage breast cancer...
  69. ncbi request reprint Mammographic screening: patterns of use and estimated impact on breast carcinoma survival
    Karen Blanchard
    Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Cancer 101:495-507. 2004
    ..In the current report, the authors describe patterns of screening use among women who were examined at a large screening and diagnostic service and estimate the added mortality associated with missed screening mammograms...
  70. ncbi request reprint Model-based predictions of BRCA1/2 mutation status in breast carcinoma patients treated at an academic medical center
    Kristen M Shannon
    Division of Hematology Oncology, Massachusetts General Hospital, Boston 02114, USA
    Cancer 94:305-13. 2002
    ....
  71. ncbi request reprint Preoperative therapy with trastuzumab and paclitaxel followed by sequential adjuvant doxorubicin/cyclophosphamide for HER2 overexpressing stage II or III breast cancer: a pilot study
    Harold J Burstein
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 21:46-53. 2003
    ..We conducted a pilot study of preoperative trastuzumab and paclitaxel, followed by surgery and adjuvant doxorubicin and cyclophosphamide chemotherapy in earlier stage breast cancer...