Nikolai Slavov

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi request reprint Constant growth rate can be supported by decreasing energy flux and increasing aerobic glycolysis
    Nikolai Slavov
    Departments of Physics and Biology and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA Department of Statistics and FAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands Electronic address
    Cell Rep 7:705-14. 2014
  2. pmc Decoupling nutrient signaling from growth rate causes aerobic glycolysis and deregulation of cell size and gene expression
    Nikolai Slavov
    Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Mol Biol Cell 24:157-68. 2013
  3. pmc Metabolic cycling without cell division cycling in respiring yeast
    Nikolai Slavov
    Departments of Biology and Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Proc Natl Acad Sci U S A 108:19090-5. 2011
  4. pmc A conserved cell growth cycle can account for the environmental stress responses of divergent eukaryotes
    Nikolai Slavov
    Departments of Physics and Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Mol Biol Cell 23:1986-97. 2012
  5. pmc Coupling among growth rate response, metabolic cycle, and cell division cycle in yeast
    Nikolai Slavov
    Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Mol Biol Cell 22:1997-2009. 2011
  6. ncbi request reprint How to regulate a gene: to repress or to activate?
    Nikolai Slavov
    Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Mol Cell 46:551-2. 2012

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Constant growth rate can be supported by decreasing energy flux and increasing aerobic glycolysis
    Nikolai Slavov
    Departments of Physics and Biology and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA Department of Statistics and FAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands Electronic address
    Cell Rep 7:705-14. 2014
    ....
  2. pmc Decoupling nutrient signaling from growth rate causes aerobic glycolysis and deregulation of cell size and gene expression
    Nikolai Slavov
    Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Mol Biol Cell 24:157-68. 2013
    ..Our observations suggest that a GR signal, which is a function of the abundance of essential natural nutrients, regulates fermentation/respiration, the GRR, and the CDC...
  3. pmc Metabolic cycling without cell division cycling in respiring yeast
    Nikolai Slavov
    Departments of Biology and Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Proc Natl Acad Sci U S A 108:19090-5. 2011
    ..These results suggest that the yeast metabolic cycle reflects a growth cycle during G1/G0 and explains our previous puzzling observation that genes annotated to the CDC increase in expression at slow growth...
  4. pmc A conserved cell growth cycle can account for the environmental stress responses of divergent eukaryotes
    Nikolai Slavov
    Departments of Physics and Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Mol Biol Cell 23:1986-97. 2012
    ....
  5. pmc Coupling among growth rate response, metabolic cycle, and cell division cycle in yeast
    Nikolai Slavov
    Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Mol Biol Cell 22:1997-2009. 2011
    ..We found that the high oxygen consumption phase of the YMC can coincide exactly with the S phase of the cell division cycle, suggesting that oxidative metabolism and DNA replication are not incompatible...
  6. ncbi request reprint How to regulate a gene: to repress or to activate?
    Nikolai Slavov
    Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Mol Cell 46:551-2. 2012
    ..Gene-expression responses to an input can depend on growth conditions; in this issue, Sasson et al. (2012) show that this dependence is lower when the input results in a high degree of promoter occupancy...