Aneesh Singhal

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Evaluating effects of normobaric oxygen therapy in acute stroke with MRI-based predictive models
    Ona Wu
    Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston MA 02114, USA
    Med Gas Res 2:5. 2012
  2. pmc Combination therapy with normobaric oxygen (NBO) plus thrombolysis in experimental ischemic stroke
    Norio Fujiwara
    Neuroprotection Research Laboratory, Departments of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    BMC Neurosci 10:79. 2009
  3. pmc Stability of large diffusion/perfusion mismatch in anterior circulation strokes for 4 or more hours
    R Gilberto Gonzalez
    Neuroradiology Division, Department of Radiology, Massachusetts General Hospital, Boston, Harvard Medical School, Boston, MA 02114, USA
    BMC Neurol 10:13. 2010
  4. ncbi request reprint Cerebral venous sinus thrombosis associated with hepatic cirrhosis
    A B Singhal
    VBK 802, Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    J Neurol Sci 171:65-8. 1999
  5. pmc Advances in emerging nondrug therapies for acute stroke 2007
    Aneesh B Singhal
    Neuroprotection Research Laboratory, Harvard Medical School, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Stroke 39:289-91. 2008
  6. ncbi request reprint A pilot study of normobaric oxygen therapy in acute ischemic stroke
    Aneesh B Singhal
    Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    Stroke 36:797-802. 2005
  7. ncbi request reprint SSRI and statin use increases the risk for vasospasm after subarachnoid hemorrhage
    A B Singhal
    Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Neurology 64:1008-13. 2005
  8. ncbi request reprint Postpartum angiopathy and other cerebral vasoconstriction syndromes
    Aneesh B Singhal
    Stroke Service, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Neurocrit Care 3:91-7. 2005
  9. ncbi request reprint Advances in stroke neuroprotection: hyperoxia and beyond
    Aneesh B Singhal
    Harvard Medical School, Boston, MA, USA
    Neuroimaging Clin N Am 15:697-720, xii-xiii. 2005
  10. doi request reprint Oxygen therapy in stroke: past, present, and future
    Aneesh B Singhal
    Massachusetts General Hospital, Stroke Research Center, 175 Cambridge Street, Suite 300, Boston, MA 02114, USA
    Int J Stroke 1:191-200. 2006

Research Grants

  1. Normobaric Hyperoxia in Acute Ischemic Stroke
    Aneesh Singhal; Fiscal Year: 2007
  2. Normobaric Hyperoxia in Acute Ischemic Stroke
    Aneesh Singhal; Fiscal Year: 2009
  3. Normobaric Hyperoxia in Acute Ischemic Stroke
    Aneesh B Singhal; Fiscal Year: 2010

Detail Information

Publications57

  1. pmc Evaluating effects of normobaric oxygen therapy in acute stroke with MRI-based predictive models
    Ona Wu
    Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston MA 02114, USA
    Med Gas Res 2:5. 2012
    ..abstract:..
  2. pmc Combination therapy with normobaric oxygen (NBO) plus thrombolysis in experimental ischemic stroke
    Norio Fujiwara
    Neuroprotection Research Laboratory, Departments of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    BMC Neurosci 10:79. 2009
    ..NBO was maintained for 3 hours. Infarct volume, brain swelling and hemorrhagic transformation were quantified at 24 hours. Outcome assessments were blinded to therapy...
  3. pmc Stability of large diffusion/perfusion mismatch in anterior circulation strokes for 4 or more hours
    R Gilberto Gonzalez
    Neuroradiology Division, Department of Radiology, Massachusetts General Hospital, Boston, Harvard Medical School, Boston, MA 02114, USA
    BMC Neurol 10:13. 2010
    ..The purpose of this study was to determine the persistence of a diffusion/perfusion mismatch in patients with ICA or proximal MCA occlusions...
  4. ncbi request reprint Cerebral venous sinus thrombosis associated with hepatic cirrhosis
    A B Singhal
    VBK 802, Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    J Neurol Sci 171:65-8. 1999
    ..He was treated with low molecular weight heparin and underwent an orthotopic liver transplant after three months. Follow-up helical CT venogram showed resolution of the sinus thrombosis...
  5. pmc Advances in emerging nondrug therapies for acute stroke 2007
    Aneesh B Singhal
    Neuroprotection Research Laboratory, Harvard Medical School, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Stroke 39:289-91. 2008
  6. ncbi request reprint A pilot study of normobaric oxygen therapy in acute ischemic stroke
    Aneesh B Singhal
    Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    Stroke 36:797-802. 2005
    ..Therapies that transiently prevent ischemic neuronal death can potentially extend therapeutic time windows for stroke thrombolysis. We conducted a pilot study to investigate the effects of high-flow oxygen in acute ischemic stroke...
  7. ncbi request reprint SSRI and statin use increases the risk for vasospasm after subarachnoid hemorrhage
    A B Singhal
    Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Neurology 64:1008-13. 2005
    ..Use of medications with vasoconstrictive or vasodilatory effects can potentially affect the risk for vasospasm after aneurysmal subarachnoid hemorrhage (SAH)...
  8. ncbi request reprint Postpartum angiopathy and other cerebral vasoconstriction syndromes
    Aneesh B Singhal
    Stroke Service, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Neurocrit Care 3:91-7. 2005
    ..This article presents an illustrative case report and reviews the historical aspects, clinical and imaging characteristics, etiology, differential diagnosis, management, and prognosis of cerebral vasoconstriction syndromes...
  9. ncbi request reprint Advances in stroke neuroprotection: hyperoxia and beyond
    Aneesh B Singhal
    Harvard Medical School, Boston, MA, USA
    Neuroimaging Clin N Am 15:697-720, xii-xiii. 2005
    ..These and other developments over the past decade raise expectations that successful stroke neuroprotection is imminent...
  10. doi request reprint Oxygen therapy in stroke: past, present, and future
    Aneesh B Singhal
    Massachusetts General Hospital, Stroke Research Center, 175 Cambridge Street, Suite 300, Boston, MA 02114, USA
    Int J Stroke 1:191-200. 2006
    ..This article reviews the history, rationale, mechanisms of action and adverse effects of hyperoxia, the key results of previous hyperoxia studies, and the potential role of oxygen therapy in contemporary stroke treatment...
  11. ncbi request reprint Postpartum angiopathy with reversible posterior leukoencephalopathy
    Aneesh B Singhal
    Stroke Service, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, 02114, USA
    Arch Neurol 61:411-6. 2004
    ..The pathophysiological features of RPLS are related to small-vessel dysfunction and breakdown of the blood-brain barrier...
  12. ncbi request reprint A review of oxygen therapy in ischemic stroke
    Aneesh B Singhal
    Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
    Neurol Res 29:173-83. 2007
    ..This article reviews the history and current rationale for using oxygen therapy in stroke, the mechanisms of action of HBO and the results of animal and human studies of hyperoxia in cerebrovascular diseases...
  13. doi request reprint Reversible cerebral vasoconstriction syndromes: analysis of 139 cases
    Aneesh B Singhal
    Department of Neurology, Massachusetts General Hospital, Boston, 02114, USA
    Arch Neurol 68:1005-12. 2011
    ..To compare the clinical, laboratory, and imaging features of patients with reversible cerebral vasoconstriction syndromes evaluated at 2 academic centers, compare subgroups, and investigate treatment effects...
  14. ncbi request reprint Cerebral vasoconstriction and stroke after use of serotonergic drugs
    A B Singhal
    Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Neurology 58:130-3. 2002
    ..These cases, and the literature, suggest that the use of serotonin-enhancing drugs can precipitate a cerebrovascular syndrome due to reversible, multifocal arterial narrowing...
  15. ncbi request reprint Diffusion-weighted magnetic resonance imaging abnormalities in Bartonella encephalopathy
    Aneesh B Singhal
    Department of Neurology, Massachusetts General Hospital, Biogen, Inc MAP, Boston, USA
    J Neuroimaging 13:79-82. 2003
    ..In patients with unexplained, refractory seizures, the presence of DWI abnormalities warrants a search for unusual infectious or inflammatory disorders, like Bartonella encephalitis...
  16. ncbi request reprint Effects of normobaric hyperoxia in a rat model of focal cerebral ischemia-reperfusion
    Aneesh B Singhal
    Neuroprotection Research Laboratory, Department of Neurology, Massachusetts General Hospital, Charlestown 02129, USA
    J Cereb Blood Flow Metab 22:861-8. 2002
    ..These results indicate that hyperoxia treatment during focal cerebral ischemia-reperfusion is neuroprotective, and does not increase oxidative stress...
  17. ncbi request reprint Acute ischemic stroke patterns in infective and nonbacterial thrombotic endocarditis: a diffusion-weighted magnetic resonance imaging study
    Aneesh B Singhal
    Stroke Service, Department of Neurology, Massachusetts General Hospital, and Harvard Medical School, Boston, Mass 02114, USA
    Stroke 33:1267-73. 2002
    ..We compared patterns of acute and recurrent ischemic stroke in IE and NBTE, using diffusion-weighted MRI (DWI)...
  18. ncbi request reprint Normobaric hyperoxia reduces MRI diffusion abnormalities and infarct size in experimental stroke
    Aneesh B Singhal
    Neuroprotection Research Laboratory, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Neurology 58:945-52. 2002
    ..Hyperbaric oxygen therapy is considered an important stroke treatment strategy...
  19. doi request reprint Clinical MRI interpretation for outcome prediction in cardiac arrest
    David Greer
    Department of Neurology, Yale University School of Medicine, LLCI 912, 15 York Street, New Haven, CT 06520, USA
    Neurocrit Care 17:240-4. 2012
    ..We sought to determine whether clinical interpretation of diffusion-weighted imaging (DWI) helps to determine poor outcome in comatose cardiac arrest patients...
  20. doi request reprint Interexaminer difference in infarct volume measurements on MRI: a source of variance in stroke research
    Hakan Ay
    Stroke Service, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Room 2301, Charlestown MA 02129, USA
    Stroke 39:1171-6. 2008
    ..We sought to quantify the variance imposed by measurement error in DWI and PWI lesion volume measurements in ischemic stroke...
  21. doi request reprint Serial MRI changes in comatose cardiac arrest patients
    David Greer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06530, USA
    Neurocrit Care 14:61-7. 2011
    ..However, MRI changes evolve temporally and spatially, which may lead to misinterpretation and misclassification of patients...
  22. pmc Wake-up stroke: clinical and neuroimaging characteristics
    Gisele S Silva
    Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA giselesampaio hotmail com
    Cerebrovasc Dis 29:336-42. 2010
    ..In these patients, in whom the time from symptom onset is uncertain, brain imaging is a potential strategy to characterize the ischemia duration and the presence of salvageable brain tissue...
  23. doi request reprint Hyperdense basilar artery sign on unenhanced CT predicts thrombus and outcome in acute posterior circulation stroke
    Gregory V Goldmakher
    Massachusetts General Hospital, Department of Neurology, MGH Stroke Research Center, 175 Cambridge Street, suite 300 Boston, MA 02114, USA
    Stroke 40:134-9. 2009
    ..Our purpose was to determine whether the hyperdense basilar artery (HDBA) sign has utility in detecting thrombosis and predicting outcome in patients presenting with signs and symptoms of posterior circulation stroke...
  24. doi request reprint Admission international normalized ratio and acute infarct volume in ischemic stroke
    Hakan Ay
    Department of Neurology, Stroke Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    Ann Neurol 64:499-506. 2008
    ..We explored the relation between admission international normalized ratio (INR) and acute infarct volume in patients with ischemic stroke...
  25. pmc Collateral vessels on CT angiography predict outcome in acute ischemic stroke
    Matthew B Maas
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Stroke 40:3001-5. 2009
    ....
  26. pmc National Institutes of Health Stroke Scale score is poorly predictive of proximal occlusion in acute cerebral ischemia
    Matthew B Maas
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Stroke 40:2988-93. 2009
    ..Use of National Institutes of Health Stroke Scale (NIHSS) score to predict a proximal arterial occlusion (PO) is suggested by several case series as a viable method of selecting cases appropriate for multimodal imaging...
  27. pmc Age-dependent susceptibility to infarct growth in women
    Figen Gokcay
    AA Martinos Center for Biomedical Imaging and Stroke Service, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Room 2301, Charlestown, MA 02129, USA
    Stroke 42:947-51. 2011
    ..We sought to identify whether the proportion of initially ischemic to eventually infarcted tissue was different between men and women with ischemic stroke...
  28. ncbi request reprint A computerized algorithm for etiologic classification of ischemic stroke: the Causative Classification of Stroke System
    Hakan Ay
    AA Martinos Center for Biomedical Imaging and Stroke Service, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Room 2301, Charlestown, MA 02129, USA
    Stroke 38:2979-84. 2007
    ..In this article, we present an automated version of the SSS-TOAST, the Causative Classification System (CCS), to facilitate its utility in multicenter settings...
  29. doi request reprint Severity of leukoaraiosis and susceptibility to infarct growth in acute stroke
    Hakan Ay
    A A Martinos Center for Biomedical Imaging and Stroke Service, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Room 2301, Charlestown, MA 02129, USA
    Stroke 39:1409-13. 2008
    ..We hypothesized that the volume of LA correlated with the proportion of initially ischemic but eventually infarcted tissue in acute human stroke...
  30. ncbi request reprint Normobaric hyperoxia extends the reperfusion window in focal cerebral ischemia
    Hahn Young Kim
    Neuroprotection Research Laboratory, Departments of Neurology and Radiology, Massachusetts General Hospital, Charlestown, USA
    Ann Neurol 57:571-5. 2005
    ..Normobaric hyperoxia may be a clinically feasible adjunct method for significantly increasing the time window for effective thrombolytic therapy in acute ischemic stroke...
  31. ncbi request reprint Reversible posterior leukoencephalopathy, cerebral vasoconstriction, and strokes after intravenous immune globulin therapy in guillain-barre syndrome
    Christine E Doss-Esper
    Department of Neurology, Division of Critical Care and Emergency Neurology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Neuroimaging 15:188-92. 2005
    ..Possible interrelationships and mechanisms of these complications are discussed...
  32. ncbi request reprint CT angiography and CT perfusion in post-CEA hyperperfusion syndrome
    Susanne Muehlschlegel
    Department of Neurology, Division of Neurocritical Care and Stroke, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Neurology 68:1437. 2007
  33. ncbi request reprint Correlation between brain reorganization, ischemic damage, and neurologic status after transient focal cerebral ischemia in rats: a functional magnetic resonance imaging study
    Rick M Dijkhuizen
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    J Neurosci 23:510-7. 2003
    ....
  34. ncbi request reprint Spontaneous hyperacute postischemic hemorrhage leading to death
    Eric E Smith
    Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Neuroimaging 14:361-4. 2004
    ..In patients with ischemic stroke, MRI findings such as hyperacute petechial hemorrhage or chronic cerebral microbleeds might predict subsequent parenchymal hemorrhage and thus have implications for tissue plasminogen activator use...
  35. pmc Connectivity alterations assessed by combining fMRI and MR-compatible hand robots in chronic stroke
    Dionyssios Mintzopoulos
    NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital and Shriner s Burn Institute, Harvard Medical School, Boston, MA 02114, USA
    Neuroimage 47:T90-7. 2009
    ..Assessing changes in connectivity by means of fMRI and MR_CHIROD might be used in the future to further elucidate the neural network plasticity that underlies functional recovery in chronic stroke patients...
  36. ncbi request reprint An evidence-based causative classification system for acute ischemic stroke
    Hakan Ay
    A A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Ann Neurol 58:688-97. 2005
    ..The SSS-TOAST is a dynamic algorithm that can accommodate modifications as new epidemiological data accumulate and diagnostic techniques advance...
  37. doi request reprint The pattern of leptomeningeal collaterals on CT angiography is a strong predictor of long-term functional outcome in stroke patients with large vessel intracranial occlusion
    Fabricio O Lima
    Stroke Service, Department of Neurology, Massachusetts General Hospital, Boston, Mass 02114, USA
    Stroke 41:2316-22. 2010
    ..The role of noninvasive methods in the evaluation of collateral circulation has yet to be defined. We hypothesized that a favorable pattern of leptomeningeal collaterals, as identified by CT angiography, correlates with improved outcomes...
  38. ncbi request reprint Cerebral vasoconstriction syndromes
    Aneesh B Singhal
    Harvard Medical School, Assistant in Neurology, Massachusetts General Hospital, and Spaulding Rehabilitation Hospital, Boston, Massachusetts, USA
    Top Stroke Rehabil 11:1-6. 2004
    ..This article reviews the history, clinical and radiological characteristics, differential diagnosis, and management of cerebral vasoconstriction syndromes...
  39. ncbi request reprint Acute brain infarct: detection and delineation with CT angiographic source images versus nonenhanced CT scans
    Erica C S Camargo
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, GRB 239, Boston, MA 02114 2622, USA
    Radiology 244:541-8. 2007
    ....
  40. ncbi request reprint Multiple punctate cerebral hemorrhages in acute leukemia with blast crisis
    Sherry H Y Chou
    J Philip Kistler Stroke Research Center, Massachusetts General Hospital, Boston, MA 02114, USA
    Neurology 68:953. 2007
  41. ncbi request reprint The real estate factor: quantifying the impact of infarct location on stroke severity
    Nina M Menezes
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and the Harvard Massachusetts Institute of Technology Division of Health Sciences and Technology, Boston, MA, USA
    Stroke 38:194-7. 2007
    ..In the current study, we sought to quantify the impact of location on neurological deficit severity and to delineate this impact from that of volume...
  42. pmc fMRI as a molecular imaging procedure for the functional reorganization of motor systems in chronic stroke
    Asimina Lazaridou
    NMR Surgical Laboratory, Massachusetts General Hospital and Shriners Burn Institute, Harvard Medical School, Boston, MA, USA
    Mol Med Rep 8:775-9. 2013
    ..These results also indicate that connectivity alterations between motor areas might assist the counterbalance of a functionally abnormal M1 in chronic stroke survivors and possibly other patients with motor dysfunction. ..
  43. ncbi request reprint Subarachnoid hemorrhage without evident cause on initial angiography studies: diagnostic yield of subsequent angiography and other neuroimaging tests
    Mehmet A Topcuoglu
    Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Neurosurg 98:1235-40. 2003
    ..The aim of this study was to assess the diagnostic yield of imaging tests performed in patients in whom the cause of subarachnoid hemorrhage (SAH) had not been demonstrated on initial angiography...
  44. ncbi request reprint Diffusion MRI in three types of anoxic encephalopathy
    Aneesh B Singhal
    Stroke Service, Department of Neurology, VBK 802, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    J Neurol Sci 196:37-40. 2002
    ..The prognosis after anoxic encephalopathy depends on the underlying mechanism and its severity, which may be reflected by DWI abnormalities...
  45. ncbi request reprint Headache: when is neurologic imaging indicated?
    Pamela W Schaefer
    Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Am Coll Radiol 4:566-9. 2007
  46. pmc Stroke Therapy Academic Industry Roundtable (STAIR) recommendations for extended window acute stroke therapy trials
    Jeffrey L Saver
    Department of Neurology, Geffen School of Medicine, UCLA, Los Angeles, CA, USA
    Stroke 40:2594-600. 2009
    ..a. thrombolysis or devices may be acceptable. Statistical considerations and definitions of successful recanalization/reperfusion are suggested for these trials...
  47. pmc Update of the stroke therapy academic industry roundtable preclinical recommendations
    Marc Fisher
    Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Stroke 40:2244-50. 2009
    ..Although the recommendations cannot be validated until effective therapies based on them emerge from clinical trials, it is hoped that adherence to them might enhance the chances for success...
  48. doi request reprint Effect of normobaric oxygen therapy in a rat model of intracerebral hemorrhage
    Norio Fujiwara
    ACC 729 C, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Stroke 42:1469-72. 2011
    ..Normobaric oxygen (NBO) therapy may be neuroprotective in acute ischemic stroke. However, how NBO may affect intracerebral hemorrhage is unclear. We tested NBO in a rat model of striatal intracerebral hemorrhage...
  49. pmc Comatose patients with cardiac arrest: predicting clinical outcome with diffusion-weighted MR imaging
    Ona Wu
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, 149 13th St, CNY 2301, Charlestown, MA 02129, USA
    Radiology 252:173-81. 2009
    ..To examine whether the severity and spatial distribution of reductions in apparent diffusion coefficient (ADC) are associated with clinical outcomes in patients who become comatose after cardiac arrest...
  50. ncbi request reprint Magnetic resonance spectroscopy study of oxygen therapy in ischemic stroke
    Aneesh B Singhal
    Stroke 38:2851-4. 2007
    ..Recent studies suggest that normobaric oxygen therapy (NBO) is neuroprotective in acute ischemic stroke...
  51. ncbi request reprint Narrative review: reversible cerebral vasoconstriction syndromes
    Leonard H Calabrese
    Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Ann Intern Med 146:34-44. 2007
    ..In this review, we describe our current understanding of RCVS; summarize its key clinical, laboratory, and imaging features; and discuss strategies for diagnostic evaluation and treatment...
  52. ncbi request reprint Oxygen therapy in ischemic stroke
    John H Zhang
    Stroke 34:e152-3; author reply e153-5. 2003
  53. ncbi request reprint Effects of common medications on cerebral vasospasm after subarachnoid haemorrhage
    Mehmet Akif Topcuoglu
    Akdeniz University Hospitals, Neurology Department, Antalya, 07059, Turkey
    Expert Opin Drug Saf 5:57-65. 2006
    ..Recognition of these pharmacological effects is important because medications that can worsen or alleviate vasospasm are frequently administered to SAH patients to treat coincident medical problems...
  54. doi request reprint Neuroprotection: lessons from a spectrum of neurological disorders
    Wendy R Galpern
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Stroke 1:97-9. 2006
  55. ncbi request reprint Primary central nervous system vasculitis: progress and questions
    Leonard H Calabrese
    Ann Neurol 62:430-2. 2007
  56. ncbi request reprint Effect of clipping, craniotomy, or intravascular coiling on cerebral vasospasm and patient outcome after aneurysmal subarachnoid hemorrhage
    Brian L Hoh
    Neurosurgical Service, Endovascular Neurosurgery and Interventional Neuroradiology, and Cerebrovascular Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Neurosurgery 55:779-86; discussion 786-9. 2004
    ..We reviewed our experience over 8 years and assessed whether clipping, craniotomy, or coiling affects patient outcomes or the risk for vasospasm...
  57. ncbi request reprint Relationship between hyperglycemia and symptomatic vasospasm after subarachnoid hemorrhage
    Neeraj Badjatia
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Crit Care Med 33:1603-9; quiz 1623. 2005
    ..To determine the relationship between blood glucose levels (mg/dL) and occurrence of symptomatic vasospasm (VSP) and clinical outcomes after aneurysmal subarachnoid hemorrhage...

Research Grants5

  1. Normobaric Hyperoxia in Acute Ischemic Stroke
    Aneesh Singhal; Fiscal Year: 2007
    ..Breathing high-flow oxygen may prove to be a simple, practical, portable, and potentially cost-effective therapy that improves stroke outcomes, either independently or by extending the time window for IV tPA. ..
  2. Normobaric Hyperoxia in Acute Ischemic Stroke
    Aneesh Singhal; Fiscal Year: 2009
    ..Breathing high-flow oxygen may prove to be a simple, practical, portable, and potentially cost-effective therapy that improves stroke outcomes, either independently or by extending the time window for IV tPA. ..
  3. Normobaric Hyperoxia in Acute Ischemic Stroke
    Aneesh B Singhal; Fiscal Year: 2010
    ..Breathing high-flow oxygen may prove to be a simple, practical, portable, and potentially cost-effective therapy that improves stroke outcomes, either independently or by extending the time window for IV tPA. ..