J P Singh

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi Masking of sinus rhythm by recipient atrial flutter in a patient with orthotopic heart transplant
    Arash Aryana
    Cardiac Arrhythmia Service, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Cardiovasc Electrophysiol 19:876-7. 2008
  2. ncbi Biventricular pacing: current trends and future strategies
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02459, USA
    Eur Heart J 33:305-13. 2012
  3. ncbi Genetic factors contribute to the variance in frequency domain measures of heart rate variability
    J P Singh
    National Heart, Lung and Blood Institute, Framingham Heart Study, Boston, MA, USA
    Auton Neurosci 90:122-6. 2001
  4. ncbi Cardiac resynchronization therapy: the MGH experience
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ann Noninvasive Electrocardiol 10:44-54. 2005
  5. ncbi Device diagnostics and long-term clinical outcome in patients receiving cardiac resynchronization therapy
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114 2696, USA
    Europace 11:1647-53. 2009
  6. ncbi "Dialing-in" cardiac resynchronization therapy: overcoming constraints of the coronary venous anatomy
    Jagmeet P Singh
    Cardiac Resynchronization Therapy Program, Heart Center and Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    J Interv Card Electrophysiol 17:51-8. 2006
  7. ncbi The coronary venous anatomy: a segmental approach to aid cardiac resynchronization therapy
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Am Coll Cardiol 46:68-74. 2005
  8. ncbi Factors influencing appropriate firing of the implanted defibrillator for ventricular tachycardia/fibrillation: findings from the Multicenter Automatic Defibrillator Implantation Trial II (MADIT-II)
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Am Coll Cardiol 46:1712-20. 2005
  9. ncbi Elusive atrial substrate: complex fractionated atrial electrograms and beyond
    Jagmeet P Singh
    Department of Medicine and Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Heart Rhythm 7:1886-90. 2010
  10. ncbi Images in cardiovascular medicine. Sleep (vagal)-induced atrial fibrillation
    Jagmeet Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Mass 02114, USA
    Circulation 110:e32-3. 2004

Detail Information

Publications45

  1. ncbi Masking of sinus rhythm by recipient atrial flutter in a patient with orthotopic heart transplant
    Arash Aryana
    Cardiac Arrhythmia Service, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    J Cardiovasc Electrophysiol 19:876-7. 2008
  2. ncbi Biventricular pacing: current trends and future strategies
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02459, USA
    Eur Heart J 33:305-13. 2012
    ..This review will highlight biventricular pacing in its present form, will elaborate on strategies to enhance response to CRT, and outline future trends and synergies towards maximizing the potential benefit of this therapeutic modality...
  3. ncbi Genetic factors contribute to the variance in frequency domain measures of heart rate variability
    J P Singh
    National Heart, Lung and Blood Institute, Framingham Heart Study, Boston, MA, USA
    Auton Neurosci 90:122-6. 2001
    ..Recognition of the genetic determinants of HRV may provide additional insight into the pathophysiology of the autonomic nervous system and offer clues toward its modulation...
  4. ncbi Cardiac resynchronization therapy: the MGH experience
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ann Noninvasive Electrocardiol 10:44-54. 2005
    ..This article provides an overview of CRT, highlights several unresolved issues and describes ongoing research efforts to address some of these important questions...
  5. ncbi Device diagnostics and long-term clinical outcome in patients receiving cardiac resynchronization therapy
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114 2696, USA
    Europace 11:1647-53. 2009
    ..This retrospective analysis sought to develop and validate a model using the measured diagnostic variables in cardiac resynchronization therapy (CRT) devices to predict mortality...
  6. ncbi "Dialing-in" cardiac resynchronization therapy: overcoming constraints of the coronary venous anatomy
    Jagmeet P Singh
    Cardiac Resynchronization Therapy Program, Heart Center and Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    J Interv Card Electrophysiol 17:51-8. 2006
    ..This electrical distancing of the leads will potentially improve the mechanics of ventricular contraction and the flexibility of RV-LV optimization...
  7. ncbi The coronary venous anatomy: a segmental approach to aid cardiac resynchronization therapy
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Am Coll Cardiol 46:68-74. 2005
    ..The current viewpoint calls for a more systematic segmental approach for describing the coronary venous anatomy...
  8. ncbi Factors influencing appropriate firing of the implanted defibrillator for ventricular tachycardia/fibrillation: findings from the Multicenter Automatic Defibrillator Implantation Trial II (MADIT-II)
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Am Coll Cardiol 46:1712-20. 2005
    ....
  9. ncbi Elusive atrial substrate: complex fractionated atrial electrograms and beyond
    Jagmeet P Singh
    Department of Medicine and Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Heart Rhythm 7:1886-90. 2010
    ..In this review, we summarize the current reasoning and controversies related to this new approach. In addition, we attempt to unravel some of the complexities of targeting these patient-specific atrial electrical signals...
  10. ncbi Images in cardiovascular medicine. Sleep (vagal)-induced atrial fibrillation
    Jagmeet Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Mass 02114, USA
    Circulation 110:e32-3. 2004
  11. ncbi Is baseline autonomic tone associated with new onset atrial fibrillation?: Insights from the framingham heart study
    Jagmeet P Singh
    National Heart, Lung and Blood Institute s Framingham Heart Study, Framingham, Massachusetts, USA
    Ann Noninvasive Electrocardiol 9:215-20. 2004
    ..Little is known about the impact of baseline autonomic tone and the development of new onset AF in a population-based cohort. The purpose of this study was to assess the role of HRV as a predictor of new onset AF...
  12. ncbi Left ventricular lead position and clinical outcome in the multicenter automatic defibrillator implantation trial-cardiac resynchronization therapy (MADIT-CRT) trial
    Jagmeet P Singh
    DPhil, GRB 109, Cardiac Arrhythmia Service, Massachusetts General Hospital Heart Center, Harvard Medical School, 55 Fruit St, Boston, MA 02114, USA
    Circulation 123:1159-66. 2011
    ....
  13. ncbi Left ventricular lead electrical delay predicts response to cardiac resynchronization therapy
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Heart Rhythm 3:1285-92. 2006
    ....
  14. ncbi Usefulness of a novel "response score" to predict hemodynamic and clinical outcome from cardiac resynchronization therapy
    E Kevin Heist
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 97:1732-6. 2006
    ..0001). Kaplan-Meier analysis associated a higher response score with improved 12-month event-free survival after CRT implantation (p=0.0019)...
  15. ncbi Potential uses of computed tomography for management of heart failure patients with dyssynchrony
    Quynh A Truong
    Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Crit Pathw Cardiol 7:185-90. 2008
    ..We present here the potential concept of using cardiac computed tomography as a single modality to acquire functional and anatomic information, and also to show the possibility of integrating this with real time fluoroscopy...
  16. ncbi Left ventricular lead proximity to an akinetic segment and impact on outcome of cardiac resynchronization therapy
    Daniel Arzola-Castaner
    Cardiac Arrhythmia Service, Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Cardiovasc Electrophysiol 17:623-7. 2006
    ..7 +/- 50.7% and ML, %DeltadP/dt 45.1 +/- 58.8% vs AL, %DeltadP/dt 2.9 +/- 30.9%, respectively, P = 0.014). CONCLUSION: LV lead proximity to an akinetic segment does not impact acute hemodynamic or 12-month clinical response to CRT...
  17. ncbi Atrial fibrillation endpoints: hospitalization
    Jeremy N Ruskin
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Heart Rhythm 1:B31-4, discussion B34-5. 2004
  18. ncbi Quantitative analysis of intraventricular dyssynchrony using wall thickness by multidetector computed tomography
    Quynh A Truong
    Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    JACC Cardiovasc Imaging 1:772-81. 2008
    ....
  19. ncbi Coronary venospasm causing chest pain during implantation of cardiac resynchronization therapy
    E Kevin Heist
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Heart Rhythm 4:1108-9. 2007
  20. ncbi Depression as a predictor for appropriate shocks among patients with implantable cardioverter-defibrillators: results from the Triggers of Ventricular Arrhythmias (TOVA) study
    William Whang
    Cardiovascular Division, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    J Am Coll Cardiol 45:1090-5. 2005
    ..We sought to examine the relationship between symptoms of depression and shock-treated ventricular arrhythmias among implantable cardioverter-defibrillator (ICD) patients...
  21. ncbi Echocardiographic measures of acute haemodynamic response after cardiac resynchronization therapy predict long-term clinical outcome
    Francois B Tournoux
    Cardiac Arrhythmia Service and Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Eur Heart J 28:1143-8. 2007
    ....
  22. ncbi Interlead distance and left ventricular lead electrical delay predict reverse remodeling during cardiac resynchronization therapy
    Faisal M Merchant
    Cardiology Division, Massachusetts General Hospital Heart Center, Harvard Medical School, Boston, Massachusetts 02114, USA
    Pacing Clin Electrophysiol 33:575-82. 2010
    ..However, the relationship between interlead distance and electrical delay in predicting CRT outcomes has not been defined...
  23. ncbi Multiple ICD discharges associated with lead fracture without triggering of high impedance alert
    David M Donaldson
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Pacing Clin Electrophysiol 32:543-6. 2009
    ....
  24. ncbi Mechanism of decrease in mitral regurgitation after cardiac resynchronization therapy: optimization of the force-balance relationship
    Jorge Solis
    Division of Cardiology, Massachusetts General Hospital, Boston, MA 02114, USA
    Circ Cardiovasc Imaging 2:444-50. 2009
    ..We hypothesized that CRT improves the comprehensive force balance acting on the valve, including favorable changes in both geometry and LV contractile function...
  25. ncbi Role of implantable cardioverter-defibrillators in patients with methadone-induced long QT syndrome
    Anshul M Patel
    Cardiac Arrhythmia Service, Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 101:209-11. 2008
    ..This small cohort of patients suggests that ICDs may be lifesaving in those subjects who continue taking methadone after initial episodes of TDP...
  26. ncbi The impact of age and gender on cardiac resynchronization therapy outcome
    Omeed Zardkoohi
    Cardiac Arrhythmia Service, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Pacing Clin Electrophysiol 30:1344-8. 2007
    ..Cardiac resynchronization therapy (CRT) outcome varies significantly among patients. We aimed to determine the impact of age, gender, and heart failure etiology on the long-term outcome of patients receiving CRT...
  27. ncbi Elevated estimated pulmonary artery systolic pressure is associated with an adverse clinical outcome in patients receiving cardiac resynchronization therapy
    Joshua Stern
    Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Pacing Clin Electrophysiol 30:603-7. 2007
    ..We sought to investigate the impact of elevated estimated pulmonary artery systolic pressure (ePASP) on clinical outcome and LV-RR after CRT...
  28. ncbi Catheter ablation of atrial flutter after orthotopic heart transplantation
    E Kevin Heist
    Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Cardiovasc Electrophysiol 15:1366-70. 2004
    ....
  29. ncbi Radiographic left ventricular-right ventricular interlead distance predicts the acute hemodynamic response to cardiac resynchronization therapy
    E Kevin Heist
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 96:685-90. 2005
    ..002). Other LV-RV measures on the posteroanterior and lateral radiographs did not correlate with the DeltadP/dt. Use of these findings may help to guide the sites of LV and RV lead placement to maximize the benefit derived from CRT...
  30. ncbi Cardiac resynchronization in patients with atrial fibrillation: a meta-analysis of prospective cohort studies
    Gaurav A Upadhyay
    Department of Medicine and the Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Am Coll Cardiol 52:1239-46. 2008
    ..This study is a meta-analysis of prospective cohort studies comparing the impact of cardiac resynchronization therapy (CRT) for patients in atrial fibrillation (AF) and sinus rhythm (SR)...
  31. ncbi Genome scan linkage results for heart rate variability (the Framingham Heart Study)
    Jagmeet P Singh
    National Heart, Lung and Blood Institute's (NHLBI) Framingham Heart Study, Framingham, Massachusetts 01702, USA
    Am J Cardiol 90:1290-3. 2002
    ..Recognition of the genetic determinants of HRV may provide additional insights into the pathophysiology of the autonomic nervous system and offer clues to its modulation...
  32. ncbi Remote magnetic navigation to guide endocardial and epicardial catheter mapping of scar-related ventricular tachycardia
    Arash Aryana
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA 02114, USA
    Circulation 115:1191-200. 2007
    ....
  33. ncbi Atrial tachycardia after ablation of persistent atrial fibrillation: identification of the critical isthmus with a combination of multielectrode activation mapping and targeted entrainment mapping
    Anshul M Patel
    Massachusetts General Hospital, Boston, MA 02114, USA
    Circ Arrhythm Electrophysiol 1:14-22. 2008
    ..In this study, this activation mapping was combined with entrainment mapping to eliminate ATs developing late after atrial fibrillation ablation...
  34. ncbi Factors affecting error in integration of electroanatomic mapping with CT and MR imaging during catheter ablation of atrial fibrillation
    E Kevin Heist
    Cardiac Arrhythmia Service and Cardiac Unit, Massachusetts General Hospital, Gray 109, 55 Fruit St, Boston, MA, 02114, USA
    J Interv Card Electrophysiol 17:21-7. 2006
    ..Strategies to reduce integration error may therefore be especially useful in patients with large LA volume...
  35. ncbi Integrating functional and anatomical information to facilitate cardiac resynchronization therapy
    Francois B Tournoux
    Cardiology Division, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Pacing Clin Electrophysiol 30:1021-2. 2007
    ..In the case displayed, prior to implantation, the lateral wall was delayed compared to the septum. The LV lead was positioned into the vein over the most delayed region, resulting in improved LV synchrony...
  36. ncbi Impact of tricuspid regurgitation and prior coronary bypass surgery on the geometry of the coronary sinus: a rotational coronary angiography study
    Dan Blendea
    Cardiac Arrhythmia Service, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Cardiovasc Electrophysiol 21:436-40. 2010
    ..The objective of this study was to examine the impact of the underlying cardiac pathology on the variability of the CS anatomy, using rotational coronary venous angiography (RCVA)...
  37. ncbi Usefulness of cardiac resynchronization therapy in the management of Doxorubicin-induced cardiomyopathy
    Olujimi A Ajijola
    Cardiac Arrhythmia, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 101:1371-2. 2008
    ..5+/-3.5 months. In conclusion, this study suggests that patients with DIC, refractory to optimal pharmacologic therapy and meeting criteria for resynchronization device implantation, may achieve sustained benefit from CRT...
  38. ncbi Prognostic value of heart rate variability footprint and standard deviation of average 5-minute intrinsic R-R intervals for mortality in cardiac resynchronization therapy patients
    F Roosevelt Gilliam
    Cardiology Associates of Northeast Arkansas, Jonesboro, AR, USA
    J Electrocardiol 40:336-42. 2007
    ....
  39. ncbi Variability of coronary venous anatomy in patients undergoing cardiac resynchronization therapy: a high-speed rotational venography study
    Dan Blendea
    Cardiology Division, Bridgeport Hospital, Yale University School of Medicine, Bridgeport, Connecticut, USA
    Heart Rhythm 4:1155-62. 2007
    ..Venography also allows visualization of the left atrial (LA) veins, which may be a potential conduit for ablative or pacing strategies given their proximity to foci that can trigger atrial fibrillation...
  40. ncbi Cardiac resynchronization therapy and its potential proarrhythmic effect
    Indranill Basu Ray
    Harvard Thorndike Electrophysiology Institute, Department of Medicine, Beth Israel Deaconess Medical Center, Guidant Corporation, St Paul, Minnesota, USA
    Clin Cardiol 30:498-502. 2007
    ..This review attempts to summarize the current information on proarrhythmia in resynchronization therapy...
  41. ncbi Role of multislice computed tomography for preprocedural evaluation before revision of a chronically implanted transvenous left ventricular lead
    Angelo Auricchio
    Division of Cardiology, Fondazione Cardiocentro Ticino, Lugano, Switzerland
    Am J Cardiol 100:1566-70. 2007
    ..In conclusion, MSCT may be used to delineate the coronary venous anatomy in patients in whom LV lead replacement is needed to help strategize whether a transvenous or transthoracic approach may be preferred for LV lead revision...
  42. ncbi Usefulness of high-speed rotational coronary venous angiography during cardiac resynchronization therapy
    Dan Blendea
    Cardiology Division, Bridgeport Hospital, Yale University School of Medicine, Bridgeport, Connecticut, USA
    Am J Cardiol 100:1561-5. 2007
    ..RCVA identified the target branch for lead implantation more often than SCVA...
  43. ncbi Influence of left atrial and ventricular volumes on the relation between mitral valve annulus and coronary sinus
    Antonio Sorgente
    Department of Cardiology, Fondazione Cardiocentro Ticino, Lugano, Switzerland
    Am J Cardiol 102:890-6. 2008
    ..Thus, MSCT should be considered as part of the selection process of potential candidate to PMA to avoid external compression of circumflex artery/marginal branch by the device...
  44. ncbi Pacing for atrioventricular block
    E Kevin Heist
    N Engl J Med 353:1742-4; author reply 1742-4. 2005
  45. ncbi Electrical therapy for advanced heart failure: is it time for a multidisciplinary approach or a new subspecialty?
    Jagmeet P Singh
    Expert Rev Cardiovasc Ther 5:811-5. 2007