Sonya S Shin

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Targeted drug-resistance testing strategy for multidrug-resistant tuberculosis detection, Lima, Peru, 2005-2008
    Gustavo E Velásquez
    Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Emerg Infect Dis 17:432-40. 2011
  2. pmc Long-term follow-up for multidrug-resistant tuberculosis
    Sonya S Shin
    Brigham and Women s Hospital, Boston, Massachusetts, USA
    Emerg Infect Dis 12:687-8. 2006
  3. pmc Effectiveness of alcohol treatment interventions integrated into routine tuberculosis care in Tomsk, Russia
    Sonya Shin
    Harvard Medical School, Brigham and Women s Hospital, Division of Global Health Equity, 75 Francis Street, Boston, MA 02115, USA
    Addiction 108:1387-96. 2013
  4. doi request reprint Impact of rapid drug susceptibility testing for tuberculosis: program experience in Lima, Peru
    S S Shin
    Division of Global Health Equity, and Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Int J Tuberc Lung Dis 16:1538-43. 2012
  5. pmc Implementing evidence-based alcohol interventions in a resource-limited setting: novel delivery strategies in Tomsk, Russia
    Sonya S Shin
    Harvard Medical School, Division of Global Health Equity, Brigham and Women s Hospital, Boston, MA 02115, USA
    Harv Rev Psychiatry 20:58-67. 2012
  6. pmc A web-based laboratory information system to improve quality of care of tuberculosis patients in Peru: functional requirements, implementation and usage statistics
    Joaquin A Blaya
    1Division of Health Sciences and Technology, Harvard Medical School MIT, 77 Massachusetts Ave Cambridge, MA 02139, USA
    BMC Med Inform Decis Mak 7:33. 2007
  7. ncbi request reprint Treatment outcomes in an integrated civilian and prison MDR-TB treatment program in Russia
    S S Shin
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, Boston, MA 02120, USA
    Int J Tuberc Lung Dis 10:402-8. 2006
  8. pmc Scale-up of multidrug-resistant tuberculosis laboratory services, Peru
    Sonya S Shin
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
    Emerg Infect Dis 14:701-8. 2008
  9. doi request reprint Mental Health Burden Among Impoverished HIV-Positive Patients in Peru
    Sonya Shin
    Division of Global Health Equity, Brigham and Women s Hospital, Boston, MA, USA, Socios En Salud Sucursal Perú, Lima, Peru, Harvard Medical School, Boston, MA, USA, Division of Infectious Diseases, Brigham and Women s Hospital, Boston MA, USA
    J Int Assoc Physicians AIDS Care (Chic) 10:18-25. 2011
  10. doi request reprint Psychosocial impact of poverty on antiretroviral nonadherence among HIV-TB coinfected patients in Lima, Peru
    Sonya Shin
    Brigham and Women s Hospital, Division of Social Medicine and Health Inequalities, Boston, MA 02115, USA
    J Int Assoc Physicians AIDS Care (Chic) 7:74-81. 2008

Detail Information

Publications43

  1. pmc Targeted drug-resistance testing strategy for multidrug-resistant tuberculosis detection, Lima, Peru, 2005-2008
    Gustavo E Velásquez
    Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Emerg Infect Dis 17:432-40. 2011
    ..The proportion of MDR TB detected by using guidelines was higher than that detected by a concurrent national drug-resistance survey, indicating that the strategy effectively identified patients for DST...
  2. pmc Long-term follow-up for multidrug-resistant tuberculosis
    Sonya S Shin
    Brigham and Women s Hospital, Boston, Massachusetts, USA
    Emerg Infect Dis 12:687-8. 2006
    ..Among 86 patients considered cured after completion of treatment, 97% remain healthy; 1 patient relapsed. Employment increased from 34% before treatment to 71%. We observed favorable long-term outcomes among MDR-TB patients...
  3. pmc Effectiveness of alcohol treatment interventions integrated into routine tuberculosis care in Tomsk, Russia
    Sonya Shin
    Harvard Medical School, Brigham and Women s Hospital, Division of Global Health Equity, 75 Francis Street, Boston, MA 02115, USA
    Addiction 108:1387-96. 2013
    ..To test the feasibility and effectiveness of brief counseling intervention (BCI) and naltrexone integrated into tuberculosis (TB) care in Tomsk, Russia...
  4. doi request reprint Impact of rapid drug susceptibility testing for tuberculosis: program experience in Lima, Peru
    S S Shin
    Division of Global Health Equity, and Division of Infectious Diseases, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Int J Tuberc Lung Dis 16:1538-43. 2012
    ..Programmatic implementation of decentralized rapid drug susceptibility testing (DST) in Lima, Peru...
  5. pmc Implementing evidence-based alcohol interventions in a resource-limited setting: novel delivery strategies in Tomsk, Russia
    Sonya S Shin
    Harvard Medical School, Division of Global Health Equity, Brigham and Women s Hospital, Boston, MA 02115, USA
    Harv Rev Psychiatry 20:58-67. 2012
    ..We also discuss the implications of these lessons learned within the context of meeting the challenge of providing evidence-based care in resource-limited settings...
  6. pmc A web-based laboratory information system to improve quality of care of tuberculosis patients in Peru: functional requirements, implementation and usage statistics
    Joaquin A Blaya
    1Division of Health Sciences and Technology, Harvard Medical School MIT, 77 Massachusetts Ave Cambridge, MA 02139, USA
    BMC Med Inform Decis Mak 7:33. 2007
    ....
  7. ncbi request reprint Treatment outcomes in an integrated civilian and prison MDR-TB treatment program in Russia
    S S Shin
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, Boston, MA 02120, USA
    Int J Tuberc Lung Dis 10:402-8. 2006
    ..Multidrug-resistant tuberculosis (MDR-TB) is a major problem in countries of the former Soviet Union in both the civilian and prison sectors...
  8. pmc Scale-up of multidrug-resistant tuberculosis laboratory services, Peru
    Sonya S Shin
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
    Emerg Infect Dis 14:701-8. 2008
    ..Hurdles included logistics, coordinating with policy, competing interests, changing personnel, communications, and evaluation. Operational research guided laboratory scale-up and identified barriers to effective capacity building...
  9. doi request reprint Mental Health Burden Among Impoverished HIV-Positive Patients in Peru
    Sonya Shin
    Division of Global Health Equity, Brigham and Women s Hospital, Boston, MA, USA, Socios En Salud Sucursal Perú, Lima, Peru, Harvard Medical School, Boston, MA, USA, Division of Infectious Diseases, Brigham and Women s Hospital, Boston MA, USA
    J Int Assoc Physicians AIDS Care (Chic) 10:18-25. 2011
    ....
  10. doi request reprint Psychosocial impact of poverty on antiretroviral nonadherence among HIV-TB coinfected patients in Lima, Peru
    Sonya Shin
    Brigham and Women s Hospital, Division of Social Medicine and Health Inequalities, Boston, MA 02115, USA
    J Int Assoc Physicians AIDS Care (Chic) 7:74-81. 2008
    ..Tuberculosis and HIV coinfection poses unique clinical and psychosocial complexities that can impact nonadherence to highly active antiretroviral treatment (HAART)...
  11. ncbi request reprint rpoB gene mutations in clinical isolates of multidrug-resistant Mycobacterium tuberculosis in northern Lima, Peru
    S S Shin
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, Boston, MA 02120 1613, USA
    Microb Drug Resist 11:26-30. 2005
    ..Isolates from 42 of these patients were subjected to DNA sequencing of the rpoB gene region responsible for rifampin resistance. We determined the frequency of types of mutations in the rpoB gene among these Peruvian isolates...
  12. pmc Alcohol consumption among men and women with tuberculosis in Tomsk, Russia
    Sonya S Shin
    Division of Global Health Equity, Brigham and Women s Hospital, Boston, MA 02115, USA
    Cent Eur J Public Health 18:132-8. 2010
    ..We conclude that Russian women with alcohol use disorders consume almost as much alcohol as men and may be at greater risk for negative social and medical consequences...
  13. pmc Development of extensively drug-resistant tuberculosis during multidrug-resistant tuberculosis treatment
    Sonya S Shin
    Division of Global Health Equity, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Respir Crit Care Med 182:426-32. 2010
    ..Preventing this amplification of resistance will likely improve clinical outcomes and delay the secondary spread of XDR-TB...
  14. ncbi request reprint Treatment of multidrug-resistant tuberculosis during pregnancy: a report of 7 cases
    Sonya Shin
    Program in Infectious Disease and Social Change, Department of Social Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Clin Infect Dis 36:996-1003. 2003
    ..In each of these 7 cases, excellent treatment outcomes were obtained for the women and their children. Under certain circumstances, MDR-TB can be successfully treated during pregnancy...
  15. ncbi request reprint Peripheral neuropathy associated with treatment for multidrug-resistant tuberculosis
    S S Shin
    Brigham and Women s Hospital, Boston Massachusetts, USA
    Int J Tuberc Lung Dis 7:347-53. 2003
    ..To review the incidence and management of peripheral neuropathy in patients receiving therapy for MDR-TB...
  16. doi request reprint How does directly observed therapy work? The mechanisms and impact of a comprehensive directly observed therapy intervention of highly active antiretroviral therapy in Peru
    Sonya Shin
    Division of Global Health Equity, Brigham and Women s Hospital, Boston, MA 02115, USA
    Health Soc Care Community 19:261-71. 2011
    ..Based on our prior quantitative and qualitative outcomes reported here, we argue that DOT of highly active antiretroviral therapy could be designed to optimise psychosocial recovery during the period of DOT...
  17. ncbi request reprint Hypokalemia among patients receiving treatment for multidrug-resistant tuberculosis
    Sonya Shin
    Division of Infectious Diseases, Brigham and Women s Hospital, Boston, MA, USA
    Chest 125:974-80. 2004
    ..Hypokalemia was observed to be an important adverse effect encountered in this cohort...
  18. ncbi request reprint Community-based treatment of multidrug-resistant tuberculosis in Lima, Peru: 7 years of experience
    Sonya Shin
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, 1620 Tremont St 3rd Floor, Boston, MA 02120 1613, USA
    Soc Sci Med 59:1529-39. 2004
    ..We describe the first such program and highlight the crucial components and most critical challenges to creating a successful community-based MDR-TB treatment program...
  19. ncbi request reprint Adverse reactions among patients being treated for MDR-TB in Tomsk, Russia
    S S Shin
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Int J Tuberc Lung Dis 11:1314-20. 2007
    ..Treatment of multidrug-resistant tuberculosis (MDR-TB) is challenging because of the toxicity of second-line medications. Little is known about whether adverse events impact treatment outcome...
  20. pmc Comprehensive treatment of extensively drug-resistant tuberculosis
    Carole D Mitnick
    Harvard Medical School, Boston, USA
    N Engl J Med 359:563-74. 2008
    ..We describe the management of extensively drug-resistant tuberculosis and treatment outcomes among patients who were referred for individualized outpatient therapy in Peru...
  21. ncbi request reprint Treatment of extensively drug-resistant tuberculosis in Tomsk, Russia: a retrospective cohort study
    Salmaan Keshavjee
    Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA
    Lancet 372:1403-9. 2008
    ..Mycobacterium tuberculosis strains that cause untreatable drug-resistant disease are a threat worldwide. We describe the treatment, management, and outcomes of patients with extensively drug-resistant tuberculosis in Tomsk, Russia...
  22. pmc Food insufficiency is a risk factor for suboptimal antiretroviral therapy adherence among HIV-infected adults in urban Peru
    Molly F Franke
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    AIDS Behav 15:1483-9. 2011
    ..R. per 5 point increase:0.91; C.I.:[0.85, 0.98]) and good baseline adherence self-efficacy (O.R.:0.25; C.I.:[0.09, 0.69]). Interventions that ensure food security for HIV-infected individuals may help sustain high levels of adherence...
  23. doi request reprint Validation and abbreviation of an HIV stigma scale in an adult spanish-speaking population in urban Peru
    Molly F Franke
    Partners In Health, Boston, MA, 02199, USA
    AIDS Behav 14:189-99. 2010
    ..The resulting abridged scale contained 21 of the 40 original items and revealed properties similar to the full Spanish version...
  24. pmc Risk factors for in-hospital mortality among children with tuberculosis: the 25-year experience in Peru
    Peter C Drobac
    Partners In Health, Boston, Massachusetts 02115, USA
    Pediatrics 130:e373-9. 2012
    ..We examined factors associated with in-hospital death among children with tuberculosis (TB). We hypothesized that a negative response to tuberculin skin testing (TST) would predict decreased survival...
  25. pmc Expanding tuberculosis case detection by screening household contacts
    Mercedes C Becerra
    Department of Social Medicine, Harvard Medical School, Boston, MA, USA
    Public Health Rep 120:271-7. 2005
    ..Our objective was to assess the feasibility and yield of a simple active case finding strategy in a high incidence population in northern Lima, Peru...
  26. pmc Risk factors and mortality associated with default from multidrug-resistant tuberculosis treatment
    Molly F Franke
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Clin Infect Dis 46:1844-51. 2008
    ....
  27. ncbi request reprint Programmes and principles in treatment of multidrug-resistant tuberculosis
    Joia S Mukherjee
    Brigham and Women s Hospital, Division of Social Medicine and Health Inequalities, Boston, MA, USA
    Lancet 363:474-81. 2004
    ..As treatment of MDR-TB becomes increasingly available in resource-poor areas, where it is needed most, further clinical and operational research is urgently needed to guide clinicians in the management of this disease...
  28. pmc Aggressive regimens for multidrug-resistant tuberculosis decrease all-cause mortality
    Carole D Mitnick
    Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 8:e58664. 2013
    ..Analysis of observational data may inform the definition of an optimized regimen...
  29. ncbi request reprint Using treatment failure under effective directly observed short-course chemotherapy programs to identify patients with multidrug-resistant tuberculosis
    M C Becerra
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Int J Tuberc Lung Dis 4:108-14. 2000
    ..Public ambulatory care centers in three districts of northern metropolitan Lima, Peru...
  30. pmc Reducing communication delays and improving quality of care with a tuberculosis laboratory information system in resource poor environments: a cluster randomized controlled trial
    Joaquin A Blaya
    Division of Global Health Equity, Brigham and Women s Hospital, Boston, Massachusetts, United States of America eHealth Systems, Santiago, Chile
    PLoS ONE 9:e90110. 2014
    ..The objective of this study was to evaluate the impact of a laboratory information system in reducing delays and the time for MDR-TB patients to culture convert (stop transmitting)...
  31. pmc Integration of alcohol use disorders identification and management in the tuberculosis programme in Tomsk Oblast, Russia
    Trini A Mathew
    Division of Infectious Diseases, University of Mississippi Medical Center, Jackson, MS 39216, USA
    Eur J Public Health 19:16-8. 2009
    ..We then hired specialists and addressed licensing requirements to provide on-site addictions care. Our experience offers a successful model in the management of co-occurring AUDs among patients with chronic medical problems...
  32. ncbi request reprint Effect of administering short-course, standardized regimens in individuals infected with drug-resistant Mycobacterium tuberculosis strains
    J J Furin
    Department of Social Medicine, Harvard Medical School, Boston, MA 02115, USA
    Eur J Clin Microbiol Infect Dis 19:132-6. 2000
    ..Development of antituberculous-drug resistance through inadvertent, inadequate therapy appears to be the most likely explanation for the increased resistance seen in these three patients...
  33. pmc Epidemiology and treatment of multidrug resistant tuberculosis
    Carole D Mitnick
    Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts 02199, USA
    Semin Respir Crit Care Med 29:499-524. 2008
    ..Further delays in scale-up, however, risk continued generation and transmission of resistant tuberculosis, as well as associated morbidity and mortality...
  34. ncbi request reprint Community-based therapy for children with multidrug-resistant tuberculosis
    Peter C Drobac
    Social Medicine and Health Inequalities, Brigham and Women s Hospital, Boston, MA 02120, USA
    Pediatrics 117:2022-9. 2006
    ....
  35. pmc Use of spatial information to predict multidrug resistance in tuberculosis patients, Peru
    Hsien Ho Lin
    Brigham and Women s Hospital, Boston, Massachusetts, USA
    Emerg Infect Dis 18:811-3. 2012
    ..We found that crude representation of spatial location at the level of the health center improved prediction of multidrug resistance...
  36. ncbi request reprint Causes of death during tuberculosis treatment in Tomsk Oblast, Russia
    T A Mathew
    Brigham and Women s Hospital, Boston, Massachusetts, USA
    Int J Tuberc Lung Dis 10:857-63. 2006
    ..Tuberculosis (TB) incidence and mortality in Russia have risen dramatically over the past 15 years...
  37. ncbi request reprint Treating multidrug-resistant tuberculosis in Tomsk, Russia: developing programs that address the linkage between poverty and disease
    S Keshavjee
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, FXB Bldg 7th floor, 651 Huntington Ave, Boston, MA 02115, USA
    Ann N Y Acad Sci 1136:1-11. 2008
    ..The model of MDR-TB care in Tomsk is applicable for other resource-poor settings facing challenges to TB and MDR-TB control...
  38. ncbi request reprint Occurrence of serious adverse effects in patients receiving community-based therapy for multidrug-resistant tuberculosis
    J J Furin
    Department of Social Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Int J Tuberc Lung Dis 5:648-55. 2001
    ..A community-based treatment program for multidrug-resistant tuberculosis (MDR-TB) in an urban shantytown of Lima, Peru...
  39. ncbi request reprint Validation of a rapid method for detection of M. tuberculosis resistance to isoniazid and rifampin in Lima, Peru
    L A Solis
    Instituto Nacional de Salud, Lima, Peru
    Int J Tuberc Lung Dis 9:760-4. 2005
    ..In Peru, where the incidence rate of TB is among the highest in South America, the National Institute of Health recently undertook the validation and implementation of the direct Griess method...
  40. ncbi request reprint Clinical and programmatic considerations in the treatment of MDR-TB in children: a series of 16 patients from Lima, Peru
    J S Mukherjee
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Int J Tuberc Lung Dis 7:637-44. 2003
    ..Tuberculosis is a common cause of morbidity and mortality for children throughout the developing world. Children may also be infected with MDR-TB, yet most developing countries do not specifically address pediatric MDR-TB...
  41. ncbi request reprint Acquisition of drug resistance in multidrug-resistant Mycobacterium tuberculosis during directly observed empiric retreatment with standardized regimens
    L L Han
    Massachusetts State Laboratory Institute, Boston, Massachusetts, USA
    Int J Tuberc Lung Dis 9:818-21. 2005
    ..In this limited group of MDR-TB patients, acquisition of resistance was common during failure of empiric drug regimens. Further study is needed to confirm these findings...
  42. ncbi request reprint Expanding global HIV treatment: case studies from the field
    J J Furin
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, FXB Bldg 7th floor, 651 Huntington Ave, Boston, MA 02115, USA
    Ann N Y Acad Sci 1136:12-20. 2008
    ..It also discusses unique programs aimed at addressing the complex realities of the world in which HIV thrives. These programs can act as models of HIV prevention and treatment...
  43. ncbi request reprint Electronic laboratory system reduces errors in National Tuberculosis Program: a cluster randomized controlled trial
    J A Blaya
    Decision Systems Group, Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
    Int J Tuberc Lung Dis 14:1009-15. 2010
    ..To evaluate the impact of the e-Chasqui laboratory information system in reducing reporting errors compared to the current paper system...

Research Grants6

  1. Evaluation of MDR-TB Treatment Strategies in Lima, Peru
    Sonya Shin; Fiscal Year: 2006
    ..abstract_text> ..
  2. Effectiveness of Alcohol Interventions Among TB Patients in Tomsk, Russia
    Sonya Shin; Fiscal Year: 2006
    ..Finally, we have a diverse interdisciplinary team that has been able to formulate an integrated biosocial and culturally-appropriate approach to treating AUDs in this population. ..
  3. Effectiveness of Alcohol Interventions Among TB Patients in Tomsk, Russia
    Sonya Shin; Fiscal Year: 2007
    ..Finally, we have a diverse interdisciplinary team that has been able to formulate an integrated biosocial and culturally-appropriate approach to treating AUDs in this population. ..
  4. Community-based accompaniment with supervised antiretrovirals in Lima, Peru
    Sonya Shin; Fiscal Year: 2009
    ....
  5. Community-based accompaniment with supervised antiretrovirals in Lima, Peru
    Sonya S Shin; Fiscal Year: 2010
    ....