Alex Sherman

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. doi request reprint Infrastructure resources for clinical research in amyotrophic lateral sclerosis
    Alexander V Sherman
    Neurological Clinical Research Institute NCRI, Massachusetts General Hospital, Boston, Massachusetts 02129, USA
    Amyotroph Lateral Scler Frontotemporal Degener 14:53-61. 2013
  2. doi request reprint Proposed BioRepository platform solution for the ALS research community
    Alex Sherman
    Neurology Clinical Trials Unit, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Amyotroph Lateral Scler 12:11-6. 2011
  3. doi request reprint Phase 2 study of sodium phenylbutyrate in ALS
    Merit E Cudkowicz
    Massachusetts General Hospital, Neurology Clinical Trials Unit, 13th Street, Charlestown, MA 02129, USA
    Amyotroph Lateral Scler 10:99-106. 2009
  4. doi request reprint Arimoclomol at dosages up to 300 mg/day is well tolerated and safe in amyotrophic lateral sclerosis
    Merit E Cudkowicz
    Neurology Clinical Trials Unit, Massachusetts General Hospital, 13th Street, Charlestown, MA 02129, USA
    Muscle Nerve 38:837-44. 2008

Detail Information

Publications4

  1. doi request reprint Infrastructure resources for clinical research in amyotrophic lateral sclerosis
    Alexander V Sherman
    Neurological Clinical Research Institute NCRI, Massachusetts General Hospital, Boston, Massachusetts 02129, USA
    Amyotroph Lateral Scler Frontotemporal Degener 14:53-61. 2013
    ....
  2. doi request reprint Proposed BioRepository platform solution for the ALS research community
    Alex Sherman
    Neurology Clinical Trials Unit, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Amyotroph Lateral Scler 12:11-6. 2011
    ..Utilizing this platform, we have created one of the largest virtual collections of ALS-related specimens available to investigators studying ALS...
  3. doi request reprint Phase 2 study of sodium phenylbutyrate in ALS
    Merit E Cudkowicz
    Massachusetts General Hospital, Neurology Clinical Trials Unit, 13th Street, Charlestown, MA 02129, USA
    Amyotroph Lateral Scler 10:99-106. 2009
    ..While the majority of subjects tolerated higher dosages of NaPB, the lowest dose (9 g/day), was therapeutically efficient in improving histone acetylation levels...
  4. doi request reprint Arimoclomol at dosages up to 300 mg/day is well tolerated and safe in amyotrophic lateral sclerosis
    Merit E Cudkowicz
    Neurology Clinical Trials Unit, Massachusetts General Hospital, 13th Street, Charlestown, MA 02129, USA
    Muscle Nerve 38:837-44. 2008
    ..Arimoclomol CSF levels increased with dose. Arimoclomol was shown to be safe, and it crosses the blood-brain barrier. Serum pharmacokinetic profiles support dosing of three times per day. An efficacy study in ALS is planned...