ALICE MARIE SHERIDAN
Affiliation: Massachusetts General Hospital
- Nuclear translocation of cytosolic phospholipase A2 is induced by ATP depletionA M Sheridan
Medical Service, Massachusetts General Hospital and the Departments of Medicine Harvard Medical School, Charlestown, Massachusetts 02129, USA
J Biol Chem 276:29899-905. 2001..Okadaic acid inhibits the ATP depletion-induced association of cPLA(2) with nuclear fractions. Thus energy deprivation results in [Ca(2+)]-induced nuclear translocation, which is partially prevented by a phosphatase inhibitor...
- PLIP, a novel splice variant of Tip60, interacts with group IV cytosolic phospholipase A(2), induces apoptosis, and potentiates prostaglandin productionA M Sheridan
Medical Services, Massachusetts General Hospital, and Department of Medicine, Harvard Medical School, Charlestown, Massachusetts 02129, USA
Mol Cell Biol 21:4470-81. 2001..Thus PLIP, a splice variant of Tip60, interacts with cPLA(2) and potentiates cPLA(2)-mediated PGE(2) production and apoptosis...
- TWO NOVEL CPLA2 BINDING PROTEINS AND CELL DEATHAlice Sheridan; Fiscal Year: 2002..The completion of this proposal will greatly enhance our understanding of the role and regulation of cPLA2 in cell injury. ..
- TWO NOVEL CPLA2 BINDING PROTEINS AND CELL DEATHAlice Sheridan; Fiscal Year: 2007..Given the large number of patients that are initiated on dialysis each year, this addresses a critical public health problem. ..