Research Topics
| S SetoguchiSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
Research Grants
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Detail Information
Publications
Ten-year trends of cardiovascular drug use after myocardial infarction among community-dwelling persons > or =65 years of ageSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 100:1061-7. 2007..The underuse of statins and BBs was marked in black patients and did not improve over time...
Evaluating uses of data mining techniques in propensity score estimation: a simulation studySoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02130, USA
Pharmacoepidemiol Drug Saf 17:546-55. 2008....- Long-term trends of angiotensin-converting enzyme inhibitor and angiotensin-receptor blocker use after heart failure hospitalization in community-dwelling seniorsSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, United States
Int J Cardiol 125:172-7. 2008..Little is known about recent trends in the use of ACEI/ARB in community-dwelling seniors... 
Gender differences in the management and prognosis of myocardial infarction among patients > or = 65 years of ageSoko Setoguchi
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 101:1531-6. 2008..Men, especially those aged > or =75 years, however, had worse short- and long-term prognoses compared with women of a similar age. The mortality was highest and the gender effect was more pronounced during the MI hospitalizations...- Tumor necrosis factor-alpha antagonist use and heart failure in elderly patients with rheumatoid arthritisSoko Setoguchi
Divisions of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard MedicalSchool, Boston, MA 02130, USA
Am Heart J 156:336-41. 2008..Although TNFAs had significant benefits in treating rheumatoid arthritis (RA), little is known whether the drugs pose an increased risk of HF in older patients with RA... - Potential causes of higher mortality in elderly users of conventional and atypical antipsychotic medicationsSoko Setoguchi
Department of Medicine, Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
J Am Geriatr Soc 56:1644-50. 2008.... - Maximum potential benefit of implantable defibrillators in preventing sudden death after hospital admission because of heart failureSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02130, USA
CMAJ 180:611-6. 2009..However, criteria to identify those who would benefit most from this therapy are lacking. We assessed the maximum potential benefit of preventing sudden death in patients with repeated hospital admissions because of heart failure... - Agreement of diagnosis and its date for hematologic malignancies and solid tumors between medicare claims and cancer registry dataSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Cancer Causes Control 18:561-9. 2007..However, linkage between cancer registry and claims data including pharmacy-dispensing information is not always available. We examined the accuracy of claims-based definitions of incident cancers and their date of diagnosis... - Propranolol and the risk of hospitalized myopathy: translating chemical genomics findings into population-level hypothesesSoko Setoguchi
Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Am Heart J 159:428-33. 2010..We tested this hypothesis in a large population to assess whether (1) propranolol use is associated with an increased risk of myopathy and (2) the concurrent use of propranolol with a statin may further increase risk of myopathy... - Statins and the risk of lung, breast, and colorectal cancer in the elderlySoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont St, Suite 3030, Boston, MA 02130, USA
Circulation 115:27-33. 2007..Long-term statin users tend to be healthier, less frail, and more adherent to therapy than nonusers, however. This could explain such apparent "protective" effects... - Hospice, opiates, and acute care service use among the elderly before death from heart failure or cancerSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Am Heart J 160:139-44. 2010..Advances in heart failure (HF) treatments have prolonged survival, but more patients die of HF than of any type of cancer. Little is known about the current practice in end-of-life (EOL) care in HF... - Tumor necrosis factor alpha antagonist use and cancer in patients with rheumatoid arthritisSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02130, USA
Arthritis Rheum 54:2757-64. 2006..This study was undertaken to estimate the association between treatment with biologic disease-modifying antirheumatic drugs (DMARDs) and development of cancer in patients with RA... - Temporal trends in adherence to cardiovascular medications in elderly patients after hospitalization for heart failureS Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Clin Pharmacol Ther 88:548-54. 2010..Black race and dialysis treatment predicted poor adherence to any medications. Adherence to BBs and SL increased modestly over time, but overall nonadherence remained high... - Improvements in long-term mortality after myocardial infarction and increased use of cardiovascular drugs after discharge: a 10-year trend analysisSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
J Am Coll Cardiol 51:1247-54. 2008..We sought to assess the relationship between increasing use of cardiovascular medications and trends in long-term prognosis after myocardial infarction (MI) in the elderly... - Clinical presentation of myocardial infarction contributes to lower use of coronary angiography in patients with chronic kidney diseaseD M Charytan
Renal Division, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
Kidney Int 71:938-45. 2007..However, the clinical features of MI do not account for its underuse in MI patients with CKD Stages 4/5. Whether reduced use of angiography in patients with advanced CKD is justified must be evaluated in formal risk-benefit analyses... - Comparison of prospective and retrospective indicators of the quality of end-of-life cancer careSoko Setoguchi
Division of General Medicine and Primary Care, Brigham and Women s Hospital, Boston, MA 02120 1613, USA
J Clin Oncol 26:5671-8. 2008..To compare prospectively and retrospectively defined benchmarks for the quality of end-of-life care, including a novel indicator for the use of opiate analgesia... - Anti-tumor necrosis factor alpha therapy and the risk of serious bacterial infections in elderly patients with rheumatoid arthritisSebastian Schneeweiss
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Arthritis Rheum 56:1754-64. 2007..To assess the association between the initiation of anti-tumor necrosis factor alpha (anti-TNFalpha) therapy and the risk of serious bacterial infections in routine care... - Angiotensin receptor blockers and angiotensin-converting enzyme inhibitors: challenges in comparative effectiveness using Medicare dataS Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Clin Pharmacol Ther 89:674-82. 2011..1. The reduced risk of SCD can be explained, at least partly, by (i) residual confounding because ARB users were healthier on unobserved domains and (ii) lack of data on EF... - Patterns of cardiovascular risk in rheumatoid arthritisD H Solomon
Division of Pharmacoepidemiology, Brigham and Women s Hospital, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
Ann Rheum Dis 65:1608-12. 2006..This study investigated the relative risk of myocardial infarction, stroke and CVD mortality in adults with rheumatoid arthritis compared with adults without rheumatoid arthritis across age groups, sex and prior CVD event status... - Comparison of cardiovascular outcomes in elderly patients with diabetes who initiated rosiglitazone vs pioglitazone therapyWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont St, Ste 3030, Boston, MA 02120, USA
Arch Intern Med 168:2368-75. 2008..We compared cardiovascular outcomes and mortality between patients initiating pioglitazone vs rosiglitazone therapy... - Trends in adherence to secondary prevention medications in elderly post-myocardial infarction patientsNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Pharmacoepidemiol Drug Saf 17:1189-96. 2008..Poor levels of medication adherence for patients with coronary heart disease (CHD) have been documented but it is unclear whether adherence has improved over time... - Explaining the cardiovascular risk associated with rheumatoid arthritis: traditional risk factors versus markers of rheumatoid arthritis severityDaniel H Solomon
Brigham and Women s Hospital, Boston Massachusetts 02115, USA
Ann Rheum Dis 69:1920-5. 2010..The authors examined the relative importance of traditional CV risk factors and RA markers in predicting CV events... - Subgroup analyses to determine cardiovascular risk associated with nonsteroidal antiinflammatory drugs and coxibs in specific patient groupsDaniel H Solomon
Brigham and Women s Hospital, 1620 Tremont Street, Boston, MA 02120, USA
Arthritis Rheum 59:1097-104. 2008..There is substantial concern regarding the potential cardiovascular adverse effects of selective coxibs and nonselective NSAIDs, but many patients with arthritis experience important clinical benefits from these agents... - Immunosuppressive medications and hospitalization for cardiovascular events in patients with rheumatoid arthritisDaniel H Solomon
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Arthritis Rheum 54:3790-8. 2006..This study was undertaken to investigate the effects of various immunosuppressive medications on the risk of cardiovascular events among a group of older patients with RA... - Associations of kidney function with cardiovascular medication use after myocardial infarctionWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
Clin J Am Soc Nephrol 3:1415-22. 2008..It is unknown whether adherence to recommended medications after myocardial infarction (MI) differs by kidney function... - Assessing residual confounding of the association between antipsychotic medications and risk of death using survey dataSebastian Schneeweiss
Division of Pharmacoepidemiology and Pharmacoeconomics, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts, USA
CNS Drugs 23:171-80. 2009..Nonrandomised studies on the causal effects of psychotropic medications may be biased by patient characteristics that are not fully adjusted... - Repeated hospitalizations predict mortality in the community population with heart failureSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02130, USA
Am Heart J 154:260-6. 2007..The impact of repeated heart failure (HF) hospitalization on mortality has not been studied for a large community population with HF. We aimed to characterize survival of patients in relation to the number of HF hospitalizations... - Risk of death associated with the use of conventional versus atypical antipsychotic drugs among elderly patientsSebastian Schneeweiss
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 021205, USA
CMAJ 176:627-32. 2007..We assessed the short-term mortality in a population-based cohort of elderly people in British Columbia who were prescribed conventional and atypical antipsychotic medications... - Ventricular arrhythmias and cerebrovascular events in the elderly using conventional and atypical antipsychotic medicationsPhilip S Wang
J Clin Psychopharmacol 27:707-10. 2007 - Treatment of older adult patients diagnosed with rheumatoid arthritis: improved but not optimalGabriela Schmajuk
Stanford University, Palo Alto, California, USA
Arthritis Rheum 57:928-34. 2007..Our objective was to determine the rate and predictors of DMARD use in a cohort of elderly patients with RA... - Bone mineral density in older adult patients with rheumatoid arthritis: an analysis of NHANES IIIMitsuyo Kinjo
Teine Keijinkai Hospital, Teine ku Sapporo city, Japan
J Rheumatol 34:1971-5. 2007..We examined the relationship between BMD and RA in a representative US population-based sample from the Third National Health and Nutrition Examination Survey (NHANES III: 1988-1994)... - Statins and the risk of colorectal cancerSoko Setoguchi
N Engl J Med 353:952-4; author reply 952-4. 2005 - Mortality and adherence to pharmacotherapy after acute myocardial infarctionMitsuyo Kinjo
JAMA 297:1877-8; author reply 1878. 2007 - Bone mineral density in adults with the metabolic syndrome: analysis in a population-based U.S. sampleMitsuyo Kinjo
Teine Keijinkai Hospital, 1 40 Maeda 1 jou 12 chou me, Teine ku, Sapporo City, Hokkaido 006 8555, Japan
J Clin Endocrinol Metab 92:4161-4. 2007..We examined this relationship in a representative U.S. population-based sample from the Third National Health and Nutrition Examination Survey (NHANES III, 1988-1994)...
Research Grants
- Utility of a New Database to Study Drug Safety during PregnancySOKO SETOGUCHI IWATA; Fiscal Year: 2007..This database based on large population-based follow-up data with linkable clinical birth data has the potential to enhance the safety of prescription drug use in pregnant women and their children. ..