Miguel Sena-Esteves

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Optimized large-scale production of high titer lentivirus vector pseudotypes
    Miguel Sena-Esteves
    Department of Surgery, The Children s Hospital of Philadelphia, Abramson Research Center, 3615 Civic Center Blvd, Philadelphia, PA 19104, USA
    J Virol Methods 122:131-9. 2004
  2. ncbi request reprint Transduction of satellite cells after prenatal intramuscular administration of lentiviral vectors
    Tippi C MacKenzie
    The Children s Institute for Surgical Science, Children s Hospital of Philadelphia, Philadelphia, 3615 Civic Center Blvd, Philadelphia, PA 19104 4318, USA
    J Gene Med 7:50-8. 2005
  3. ncbi request reprint Transduction of human glial and neuronal tumor cells with different lentivirus vector pseudotypes
    Sabine Steffens
    Surgery Department, Abramson Research Center, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Neurooncol 70:281-8. 2004
  4. ncbi request reprint Efficient transduction of liver and muscle after in utero injection of lentiviral vectors with different pseudotypes
    Tippi C MacKenzie
    Children s Institute for Surgical Science, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Mol Ther 6:349-58. 2002
  5. ncbi request reprint Dihydrotestosterone stimulates proliferation and differentiation of fetal calvarial osteoblasts and dural cells and induces cranial suture fusion
    Ines C Lin
    Division of Plastic Surgery and Pediatric General, The Children s Institute for Surgical Science, The Children s Hospital of Philadelphia, PA 19104 4399, USA
    Plast Reconstr Surg 120:1137-47. 2007

Research Grants

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Optimized large-scale production of high titer lentivirus vector pseudotypes
    Miguel Sena-Esteves
    Department of Surgery, The Children s Hospital of Philadelphia, Abramson Research Center, 3615 Civic Center Blvd, Philadelphia, PA 19104, USA
    J Virol Methods 122:131-9. 2004
    ..The best conditions for each individual pseudotype yielded lentivirus vector stocks with titers above 1 x 10(9) tu/mL for most pseudotypes, and higher than 1 x 10(10) tu/mL for VSV-G...
  2. ncbi request reprint Transduction of satellite cells after prenatal intramuscular administration of lentiviral vectors
    Tippi C MacKenzie
    The Children s Institute for Surgical Science, Children s Hospital of Philadelphia, Philadelphia, 3615 Civic Center Blvd, Philadelphia, PA 19104 4318, USA
    J Gene Med 7:50-8. 2005
    ..In this study we performed experiments to further define the morphology and function of these cells...
  3. ncbi request reprint Transduction of human glial and neuronal tumor cells with different lentivirus vector pseudotypes
    Sabine Steffens
    Surgery Department, Abramson Research Center, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
    J Neurooncol 70:281-8. 2004
    ....
  4. ncbi request reprint Efficient transduction of liver and muscle after in utero injection of lentiviral vectors with different pseudotypes
    Tippi C MacKenzie
    Children s Institute for Surgical Science, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Mol Ther 6:349-58. 2002
    ..m. and i.h. injection of all three vectors. Our findings of long-term transduction of skeletal myocytes and cardiomyocytes after in utero administration suggest a novel strategy for the treatment of congenital muscular dystrophies...
  5. ncbi request reprint Dihydrotestosterone stimulates proliferation and differentiation of fetal calvarial osteoblasts and dural cells and induces cranial suture fusion
    Ines C Lin
    Division of Plastic Surgery and Pediatric General, The Children s Institute for Surgical Science, The Children s Hospital of Philadelphia, PA 19104 4399, USA
    Plast Reconstr Surg 120:1137-47. 2007
    ..These experiments characterize the influence of androgen stimulation on growth and differentiation of fetal dural and calvarial bone cells and on cranial suture fusion...

Research Grants1

  1. Gene delivery methods for global therapy in the CNS
    Miguel Esteves; Fiscal Year: 2007
    ..We anticipate the findings from these experiments to be applicable to other models of LSDs, and that in the near future they can be evaluated in a large animal model of GM1-gangliosidosis before moving to clinical trials. ..