Research Topics
| J D SchmahmannSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
An fMRI study of intra-individual functional topography in the human cerebellumCatherine J Stoodley
Cognitive Behavioral Neurology Unit, Massachusetts General Hospital and Harvard Medical School, 175 Cambridge Street, Boston, MA 02114, USA
Behav Neurol 23:65-79. 2010..Inter-subject variability of motor and non-motor topography remains to be determined...
Atypical case of Wolfram syndrome revealed through targeted exome sequencing in a patient with suspected mitochondrial diseaseDaniel S Lieber
Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA
BMC Med Genet 13:3. 2012....
The complex history of the fronto-occipital fasciculusJeremy D Schmahmann
Ataxia Unit, Cognitive Behavioral Neurology Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
J Hist Neurosci 16:362-77. 2007..Our analysis of brain fiber pathways using isotope anterograde tract tracers (Schmahmann & Pandya, 2006) resolves the earlier uncertainties and provides hypotheses regarding functions of these fiber pathways...- Association fibre pathways of the brain: parallel observations from diffusion spectrum imaging and autoradiographyJeremy D Schmahmann
Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston MA 02114, USA
Brain 130:630-53. 2007..By replicating the major features of these tracts identified by histological techniques in monkey, we show that DSI has the potential to cast new light on the organization of the human brain in the normal state and in clinical disorders... - Evaluation of the assessment and grading of medical students on a neurology clerkshipJeremy D Schmahmann
Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Neurology 70:706-12. 2008.... - Disconnection syndromes of basal ganglia, thalamus, and cerebrocerebellar systemsJeremy D Schmahmann
Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Cortex 44:1037-66. 2008..This model enables the formulation and testing of future hypotheses in investigations using evolving magnetic resonance imaging techniques in humans, and in clinical studies in patients with cortical and subcortical lesions... - Cerebral white matter: neuroanatomy, clinical neurology, and neurobehavioral correlatesJeremy D Schmahmann
Ataxia Unit, Cognitive Behavioral Neurology Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
Ann N Y Acad Sci 1142:266-309. 2008.... - Cerebellar stroke without motor deficit: clinical evidence for motor and non-motor domains within the human cerebellumJ D Schmahmann
Ataxia Unit, Cognitive Behavioral Neurology Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Suite 340, Charles River Plaza South, 175 Cambridge Street, Boston, MA 02114, USA
Neuroscience 162:852-61. 2009..To determine whether there are non-motor regions of cerebellum in which sizeable infarcts have little or no impact on motor control... - Development of a brief ataxia rating scale (BARS) based on a modified form of the ICARSJeremy D Schmahmann
Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
Mov Disord 24:1820-8. 2009..90 and 0.92 respectively; and inter-rater reliability (intraclass correlation coefficient) was 0.91 and 0.93 respectively. BARS is valid, reliable, and sufficiently fast and accurate for clinical purposes... - Disorders of the cerebellum: ataxia, dysmetria of thought, and the cerebellar cognitive affective syndromeJeremy D Schmahmann
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
J Neuropsychiatry Clin Neurosci 16:367-78. 2004..Cognitive and emotional disorders may accompany cerebellar diseases or be their principal clinical presentation, and this has significance for the diagnosis and management of patients with cerebellar dysfunction... - Motor projections to the basis pontis in rhesus monkeyJeremy D Schmahmann
Department of Neurology VBK 915, Massachusetts General Hospital and Harvard Medical School, Fruit Street, Boston, Massachusetts 02114, USA
J Comp Neurol 478:248-68. 2004.... - The human basis pontis: motor syndromes and topographic organizationJeremy D Schmahmann
Department of Neurology VBK 915, Massachusetts General Hospital, Fruit Street, Boston, MA 02114, USA
Brain 127:1269-91. 2004.... - Plasmapheresis improves outcome in postinfectious cerebellitis induced by Epstein-Barr virusJeremy D Schmahmann
Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Neurology 62:1443. 2004 - Ataxia after pontine stroke: insights from pontocerebellar fibers in monkeyJeremy D Schmahmann
Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Ann Neurol 55:585-9. 2004.... - Vascular syndromes of the thalamusJeremy D Schmahmann
Department of Neurology, VBK 915, Massachusetts General Hospital, Fruit St, Boston, MA 02114, USA
Stroke 34:2264-78. 2003..This article reviews the anatomy, connections, and functions of the thalamic nuclei, their vascular supply, and the clinical syndromes that result from thalamic infarction... - The role of the cerebellum in cognition and emotion: personal reflections since 1982 on the dysmetria of thought hypothesis, and its historical evolution from theory to therapyJeremy D Schmahmann
Ataxia Unit, Laboratory for Neuroanatomy and Cerebellar Neurobiology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Neuropsychol Rev 20:236-60. 2010.... - The neuropsychiatry of the cerebellum - insights from the clinicJeremy D Schmahmann
Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
Cerebellum 6:254-67. 2007.... - Prefrontal cortex projections to the basilar pons in rhesus monkey: implications for the cerebellar contribution to higher functionJ D Schmahmann
Department of Neurology, Massachusetts General Hospital, Boston 02114, USA
Neurosci Lett 199:175-8. 1995..These findings strengthen the observation that the cerebrocerebellar system incorporates associative cerebral regions, and they enhance the notion that the cerebellum participates in the organization of cognitive function... - Cerebral white matter--historical evolution of facts and notions concerning the organization of the fiber pathways of the brainJeremy D Schmahmann
Department of Neurology, Cognitive Behavioral Neurology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
J Hist Neurosci 16:237-67. 2007.... - Cognition, emotion and the cerebellumJeremy D Schmahmann
Ataxia Unit, Massachusetts General Hospital Boston, MA, USA
Brain 129:290-2. 2006 - Evidence for topographic organization in the cerebellum of motor control versus cognitive and affective processingCatherine J Stoodley
Ataxia Unit, Cognitive Behavioral Neurology Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, 175 Cambridge Street, Boston, MA 02114, USA
Cortex 46:831-44. 2010..These observations provide testable hypotheses for future investigations... - The cerebellum and language: evidence from patients with cerebellar degenerationCatherine J Stoodley
Ataxia Unit, Cognitive Behavioral Neurology Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, United States
Brain Lang 110:149-53. 2009.... - Hypertrophic pachymeningitis and cerebral venous sinus thrombosis in inflammatory bowel diseaseZongqi Xia
Department of Neurology, Brigham and Women s Hospital, Boston, Massachusetts, USA
J Clin Neurosci 17:1454-6. 2010..This report highlights the challenges of the diagnosis and management of hypertrophic pachymeningitis from an unusual primary cause... - Functional topography in the human cerebellum: a meta-analysis of neuroimaging studiesCatherine J Stoodley
Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Neuroimage 44:489-501. 2009..Prospective studies of multiple domains within single individuals are necessary to better elucidate neurobehavioral structure-function correlations in the cerebellar posterior lobe... - Evidence for reduced cerebellar volumes in trichotillomaniaNancy J Keuthen
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
Biol Psychiatry 61:374-81. 2007..Limited knowledge exists regarding the neurobiology of trichotillomania (TTM). Cerebellum (CBM) volumes were explored, given its role in complex, coordinated motor sequences... - Adult onset leukodystrophy with neuroaxonal spheroids: clinical, neuroimaging and neuropathologic observationsStefanie H Freeman
C S Kubik Laboratory for Neuropathology, Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
Brain Pathol 19:39-47. 2009..These observations lend further support to the notion that white matter disease alone can account for dementia... - Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibersV J Wedeen
Department of Radiology, MGH Martinos Center for Biomedical Imaging, Harvard Medical School, Charlestown, MA 02129, USA
Neuroimage 41:1267-77. 2008..These findings indicate that DSI tractography is able to image crossing fibers in neural tissue, an essential step toward non-invasive imaging of connectional neuroanatomy... - Human cerebellar responses to brush and heat stimuli in healthy and neuropathic pain subjectsD Borsook
PAIN Group, Brain Imaging Center, McLean Hospital, Harvard Medical School, Massachusetts, USA
Cerebellum 7:252-72. 2008..These results lead us to propose that the cerebellum may modulate the emotional and cognitive experience that distinguishes the perception of pain from the appreciation of innocuous sensory stimulation... - Human cerebellum: surface-assisted cortical parcellation and volumetry with magnetic resonance imagingNikos Makris
Massachusetts General Hospital, USA
J Cogn Neurosci 15:584-99. 2003..The SAP technique makes it possible to represent multimodal structural and functional imaging data on the flattened surface of the cerebellar cortex as illustrated in one functional MRI experiment... - Pathological laughter and crying in patients with multiple system atrophy-cerebellar typeJosef Parvizi
Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
Mov Disord 22:798-803. 2007..Our findings are consistent with the view that the cerebellum and its interconnected structures may be involved in the regulation of emotional expression... - Delayed leukoencephalopathy after hypoxic-ischemic injuryAlice S Chen-Plotkin
Department of Neurology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
Arch Neurol 65:144-5. 2008 - Myotonic dystrophy type 1 presenting with ventilatory failureNizar Souayah
Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
J Clin Neuromuscul Dis 9:252-5. 2007..To report a series of patients with adult onset myotonic dystrophy type 1 (DM1) in whom the presenting symptom was ventilatory failure... - Arginine test is not reliable for diagnosing cerebellar multiple system atrophyRaquel C Gardner
Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Ann Neurol 67:404-8. 2010..Thirty-six percent of ILOCA subjects and 40 percent of healthy controls mounted responses <4 microg/l GH. Arginine thus appears to be unreliable for the diagnosis of MSAc... - Compressive myelopathy presenting as cervical cord neurapraxia: a differential diagnosis of TIAThomas Cochrane
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Neurology 65:1140-1. 2005 - Diagnosis and management of pathological laughter and cryingJosef Parvizi
Department of Neurology, University of California Los Angeles, 710 Westwood Plaza, Los Angeles, CA 90095, USA
Mayo Clin Proc 81:1482-6. 2006..This article focuses on the clinical presentation, diagnosis, prevalence, and proposed pathophysiological mechanisms of and available treatment options for this clinical phenomenon... - MRI-based surface-assisted parcellation of human cerebellar cortex: an anatomically specified method with estimate of reliabilityNikos Makris
Center for Morphometric Analysis, MGH East, 149 13th Street, Charlestown, MA 02129, USA
Neuroimage 25:1146-60. 2005..933. Whereas the individual units provide a high level of detail and anatomical specificity, the clusters add flexibility to the analysis by providing higher reliability... - Ataxia and cerebellar atrophy--a novel manifestation of neuro-Behçet disease?Raquel C Gardner
Mov Disord 23:307-8. 2008
Research Grants
- Cognitive Effects of Cerebellar Lesions in HumansJEREMY SCHMAHMANN; Fiscal Year: 2006..This study has implications for the recognition and treatment of disorders of higher order function in cerebellar patients. ..
- Diffusion MRI of Complex White Matter and ConnectivityVan J Wedeen; Fiscal Year: 2010....