Steven Safren

..S. living with HIV and have the greatest number of new infections. This study was designed to test a brief, culturally relevant prevention intervention for HIV-infected MSM, which could be integrated into HIV care...

..The present study tested cognitive behavioral therapy for adherence and depression (CBT-AD) in patients with HIV and depression in active substance abuse treatment for injection drug use...

..The relationship of these measures to treatment outcomes can and should be examined in clinical trials of ART in resource-limited settings using similar methodologies...

..This case provides an example of how to add specific cognitive-behavioral techniques to coming-out issues within the context of a more eclectic, longer-term therapy...

..02). These data support the hypothesis that CBT for adults with ADHD with residual symptoms is a feasible, acceptable, and potentially efficacious next-step treatment approach, worthy of further testing...

..This may assist in delineating targets for interventions, as well as assessments of functional outcomes that are sensitive to change in this population...

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..Objective evidence of reductions in high-risk behavior in these 3 groups, which account for the majority of HIV transmissions in the United States, has critical implications for reducing the overall rate of new HIV infections...

..To evaluate cognitive-behavioral therapy to enhance medication adherence and reduce depression (CBT-AD) in individuals with HIV...

..One of the potential causes of residual symptoms of ADHD in adults can be difficulties with consistent adherence to medications...

..MSM who are not married, sex workers, and those who perceive they are at risk for acquiring HIV may be of higher risk for symptoms of depression...

..Attention-deficit/hyperactivity disorder (ADHD) in adulthood is a prevalent, distressing, and impairing condition that is not fully treated by pharmacotherapy alone and lacks evidence-based psychosocial treatments...

..These results provide support for continued psychosocial interventions that target these variables among patients with HIV...

..While the provision of a reminder system helped improve adherence, it is likely that more intensive interventions are required for patients with pre-existing problems...

..Addressing co-occurring psychosocial risk factors is apt to improve effect sizes of current HIV prevention interventions and allow for more effective uptake by MSM...

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..Anxiety, as manifested by PTSD symptoms should be routinely assessed among patients with HIV, and variables such as death anxiety, social support, and depression are appropriate targets for mental health interventions...

..Further research on these strategies in the context of well-controlled trials is an essential step for helping reduce disability and distress among this cohort of patients...

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..This demonstration project provides initial evidence for the ability to recruit HIV-infected MSM in care into a peer-based intervention study, and shows how a peer-based intervention can be delivered in the context of HIV care...

..Effect sizes were large for both measures of depression (Cohen's d = 1.45 for Hamilton rating scale for depression and 1.31 for Beck depression inventory), suggesting that larger scale trials are warranted...

..Differentiating risk behavior by venue type provides valuable information with which to effectively target interventions to reach MSM at greatest risk...

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..Study findings can be used to generate hypotheses for designing and providing tailored primary and secondary prevention interventions for this at-risk subgroup of MSM...

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..However, these models generally do not account for the influence of clinically significant psychological problems such as major depression...

..Because mental health is a key component of overall quality of life, HIV providers who work with MSM can use these data to increase awareness of the types of mental concerns that are most distressing to this population...

..Multidimensional assessments of quality of life in HIV may help specify targets sensitive to psychosocial interventions...

..These results provide insights about strengths and limitations of this psychotherapy with medically ill patients and may help to maximize intervention effectiveness and client acceptability...

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..It is critically important to obtain more information on the effectiveness of medications over time for patients who initially responded to pharmacotherapy for panic disorder...

..Its relationship to treatment adherence, however, has not been systematically reviewed. We used meta-analysis to examine the relationship between depression and treatment nonadherence in patients with type 1 and type 2 diabetes...

..Additional research is warranted to understand the social identity of barebacking among MSM in order to develop more nuanced prevention strategies...

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..2); and Hopkins Symptom Checklist-25, depression subscale (d = 2.0) scores. Likewise, the severity of (culturally related) headache-and orthostasis-cued panic attacks improved significantly across treatment..

..Only sparse evidence from controlled clinical trials is available to guide the psychiatric treatment of persons with HIV/AIDS...

..The article concludes with a discussion of future directions and critical questions that must be addressed in this area of clinical research...

..In the context of a randomized controlled trial (RCT) on HIV testing in the emergency department (ED) setting, we evaluated preferences for survey modality and data quality arising from each modality...

..Accessible outreach services for MSM such as mobile van services need to include drug screening and interventions that triage men into treatment programs; year-round availability of van services is warranted...

..Innovative ways of monitoring adherence while maintaining standardization across sites are required in multisite trials...

..Efforts by health care providers to address these factors may result in better treatment outcomes, enhanced quality of life among HIV patients, and decreased HIV transmission...

..We examined the association between depression, measured as either a continuous symptom severity score or a clinical disorder variable, with self-care behaviors in type 2 diabetes...

..We conclude that 1-month recall periods may be more accurate than 3- or 7-day periods, and that items that ask respondents to rate their adherence may be more accurate than those that ask about frequencies or percents...

..Upper-limb pain disorders are relatively common, and often result in disability, lost time from work, and significant use of healthcare services...

..The study also draws attention to the need for associated mental health, functional and quality-of life impairments that seem to accompany continued use in individuals with HIV...

..These results confirm the importance of screening for infectious diseases among individuals with severe and persistent mental illness...

..17), and Symptom Checklist 90-R subscales (d = 2.77). Likewise, the severity of (culturally related) neck-focused and orthostasis-cued panic attacks, including flashbacks associated with these subtypes, improved across treatment...

..Though limited, the current literature suggests that psychosocial interventions that target these factors could help reduce HIV/AIDS disparities between Latinos and whites and could have important public health value...

..Future HIV-prevention studies recruiting MSM at increased sexual risk of HIV infection should address participants potentially becoming sexual partners with each other...

..Additionally, HIV prevention work with this population should provide comprehensive education about HIV testing and risk reduction counseling that focuses on communication about serostatus and safety in sexual situations...

..This article presents an explanation of PrEP adherence for African serodiscordant couples derived from qualitative data...

..Physicians' limited knowledge of patients' antiretroviral adherence may reduce their ability to perform effective adherence counseling...

..Multipronged interventions to decrease sexual risk taking among male sex workers would also benefit from addressing the unique socioeconomic and legal needs of this population...

..Understanding the demographic and behavioral predictors of intent-to-use PrEP may prove useful to identify clinical trial participants...

..These data point to several important barriers to HIV prevention among MSM in South India and lay the groundwork for enhancing the use of outreach workers to play a role in HIV prevention in this population...

..These findings are discussed in terms of biological and behavioral factors that may influence the development of anxiety disorders after the experience of a traumatic event...

..Finally, the panel identified a broad range of intervention approaches, and conditions under which these interventions are likely to be most effective at reducing barriers to adherence and reinforcing adherence behavior...

..LEVEL OF EVIDENCE: Level II, diagnostic study. See the Guidelines for Authors for a complete description of levels of evidence...

..quot; The item clustering within the factor solution of both the ASI and Augmented ASI illustrates the role of cultural syndromes in generating fear of mental and bodily events...

..These treatments, however, require further study for replication, extension and refinement. Finally, we suggest future directions for the application of psychosocial treatments to the problems of adults with ADHD...

..These methods incorporate efficient, precise, and clear graphical data; cartographical techniques focused on judicious use of color intensities; and animation that increases engagement and accentuates information transfer...

..The result of this process is an example of an intervention developed with strong input from the community and other stakeholders, which is ready for further testing in a randomized controlled trial...

..Secondary HIV prevention interventions for youth represent a possible mode through which to deliver individually tailored adherence skill building and counseling to improve medication adherence...

..These findings confirm NP impairment in HIV-infected substance abusing patients independent of comorbid depression and severity of substance use...

..Results suggest that interventions with transgender male-to-female sex workers must be at multiple levels and address the psychosocial and environmental contexts in which sexual risk behavior occurs...

..The item clustering within the factor solution of both the ASI and Augmented ASI illustrates the role of cultural syndromes in generating fear of mental and bodily events...

..Finding ways to identify RDS seeds that are consistently generative may facilitate collecting a sample that is closer to reflecting the MSM who live in all of the communities in a given location or study sample...

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..These findings provide further support for the assertion that social anxiety disorder has important implications for clients' quality of life and that CBGT can successfully impact several domains of satisfaction...

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..Practice guidelines to date all recommend multimodal intervention, given that a significant number of patients cannot tolerate, do not respond to, or fail to reach optimal outcomes with medication alone...

..These data highlight the importance of reducing the cost of antiretroviral medications, involving family members in HIV care, and addressing privacy issues and stigma in counseling interventions in this setting...

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..Endpoints were ratings by a blinded independent assessor and patient self-report data. We propose to build on this work by conducting an adequately-powered efficacy study comparing CBT to a credible, placebo-control psychotherapy. ..

..Following successful formative work through our NIMH R21, we propose a full-scale randomized controlled efficacy trial of cognitive behavioral therapy for adherence and depression in HIV. ..

..2001) in conjunction with physician feedback regarding baseline study assessments. Participants will be followed for one-year post-randomization. ..

..Both groups-will receive diabetes education from a dietitian and a diabetes nurse educator. ..

..Both groups-will receive diabetes education from a dietitian and a diabetes nurse educator. ..

..Both groups-will receive diabetes education from a dietitian and a diabetes nurse educator. ..

..Participants will be followed for one-year post-randomization. ..

..Both groups-will receive diabetes education from a dietitian and a diabetes nurse educator. ..

..Following successful formative work through our NIMH R21, we propose a full-scale randomized controlled efficacy trial of cognitive behavioral therapy for adherence and depression in HIV. ..