Pardis Sabeti

Summary

Affiliation: Massachusetts Institute of Technology
Country: USA

Publications

  1. ncbi A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking
    Rachel Daniels
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
    Malar J 7:223. 2008
  2. ncbi Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence
    Daniel E Neafsey
    Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA
    Genome Biol 9:R171. 2008
  3. ncbi Genome-wide detection and characterization of positive selection in human populations
    Pardis C Sabeti
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, USA
    Nature 449:913-8. 2007
  4. ncbi The case for selection at CCR5-Delta32
    Pardis C Sabeti
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America
    PLoS Biol 3:e378. 2005
  5. ncbi Searching for signals of evolutionary selection in 168 genes related to immune function
    Emily C Walsh
    Novartis Institutes for BioMedical Research, 250 Mass Ave, Cambridge, MA 02139, USA
    Hum Genet 119:92-102. 2006
  6. ncbi Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection
    Gaurav Bhatia
    Harvard Massachusetts Institute of Technology MIT Division of Health, Science and Technology, Cambridge, USA
    Am J Hum Genet 89:368-81. 2011
  7. ncbi A second generation human haplotype map of over 3.1 million SNPs
    Kelly A Frazer
    The Scripps Research Institute, 10550 North Torrey Pines Road MEM275, La Jolla, California 92037, USA
    Nature 449:851-61. 2007
  8. ncbi Signatures of strong population differentiation shape extended haplotypes across the human CD28, CTLA4, and ICOS costimulatory genes
    Vincent Butty
    Section on Immunology and Immunogenetics, Joslin Diabetes Center, MA 02215, USA
    Proc Natl Acad Sci U S A 104:570-5. 2007
  9. ncbi A malaria fingerprint in the human genome?
    Johanna P Daily
    N Engl J Med 358:1855-6. 2008
  10. ncbi Pardis Sabeti profile. Picking up evolution's beat
    Michael Balter
    Science 320:442-3. 2008

Detail Information

Publications12

  1. ncbi A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking
    Rachel Daniels
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
    Malar J 7:223. 2008
    ....
  2. ncbi Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence
    Daniel E Neafsey
    Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA
    Genome Biol 9:R171. 2008
    ..To that end, we have developed a high throughput single nucleotide polymorphism (SNP) genotyping platform for P. falciparum...
  3. ncbi Genome-wide detection and characterization of positive selection in human populations
    Pardis C Sabeti
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, USA
    Nature 449:913-8. 2007
    ....
  4. ncbi The case for selection at CCR5-Delta32
    Pardis C Sabeti
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America
    PLoS Biol 3:e378. 2005
    ..More broadly, the results have general implications for the design of future studies to detect the signs of positive selection in the human genome...
  5. ncbi Searching for signals of evolutionary selection in 168 genes related to immune function
    Emily C Walsh
    Novartis Institutes for BioMedical Research, 250 Mass Ave, Cambridge, MA 02139, USA
    Hum Genet 119:92-102. 2006
    ....
  6. ncbi Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection
    Gaurav Bhatia
    Harvard Massachusetts Institute of Technology MIT Division of Health, Science and Technology, Cambridge, USA
    Am J Hum Genet 89:368-81. 2011
    ..The most significantly differentiated marker in our analysis, rs2920283, is highly differentiated in both Africa and East Asia and has prior genome-wide significant associations to bladder and gastric cancers...
  7. ncbi A second generation human haplotype map of over 3.1 million SNPs
    Kelly A Frazer
    The Scripps Research Institute, 10550 North Torrey Pines Road MEM275, La Jolla, California 92037, USA
    Nature 449:851-61. 2007
    ..Finally, we demonstrate increased differentiation at non-synonymous, compared to synonymous, SNPs, resulting from systematic differences in the strength or efficacy of natural selection between populations...
  8. ncbi Signatures of strong population differentiation shape extended haplotypes across the human CD28, CTLA4, and ICOS costimulatory genes
    Vincent Butty
    Section on Immunology and Immunogenetics, Joslin Diabetes Center, MA 02215, USA
    Proc Natl Acad Sci U S A 104:570-5. 2007
    ....
  9. ncbi A malaria fingerprint in the human genome?
    Johanna P Daily
    N Engl J Med 358:1855-6. 2008
  10. ncbi Pardis Sabeti profile. Picking up evolution's beat
    Michael Balter
    Science 320:442-3. 2008
  11. ncbi Spread of an inactive form of caspase-12 in humans is due to recent positive selection
    Yali Xue
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambs CB10 1SA, United Kingdom
    Am J Hum Genet 78:659-70. 2006
    ..We further propose that its selective advantage was sepsis resistance in populations that experienced more infectious diseases as population sizes and densities increased...
  12. ncbi Is G6PD A- deficiency associated with recurrent stillbirths in The Gambia?
    Giorgio Sirugo
    Am J Med Genet A 128:104-5. 2004