K M Rexrode

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Relationship of total and abdominal adiposity with CRP and IL-6 in women
    Kathryn M Rexrode
    Center of Cardiovascular Disease Prevention, Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Ann Epidemiol 13:674-82. 2003
  2. pmc Telomere length and ischaemic stroke in women: a nested case-control study
    M Schurks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Eur J Neurol 20:1068-74. 2013
  3. pmc Alcohol consumption and risk of stroke in women
    Monik Jimenez
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Stroke 43:939-45. 2012
  4. ncbi request reprint Sex hormone levels and risk of cardiovascular events in postmenopausal women
    Kathryn M Rexrode
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave E, Boston, Mass 02215, USA
    Circulation 108:1688-93. 2003
  5. pmc Polymorphisms and haplotypes of the estrogen receptor-beta gene (ESR2) and cardiovascular disease in men and women
    Kathryn M Rexrode
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Clin Chem 53:1749-56. 2007
  6. ncbi request reprint Abdominal and total adiposity and risk of coronary heart disease in men
    K M Rexrode
    Division of Preventive Medicine, Boston, Massachusetts 02215, USA
    Int J Obes Relat Metab Disord 25:1047-56. 2001
  7. pmc Emerging risk factors in women
    Kathryn M Rexrode
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Mass, USA
    Stroke 41:S9-11. 2010
  8. ncbi request reprint A prospective study of body mass index, weight change, and risk of stroke in women
    K M Rexrode
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    JAMA 277:1539-45. 1997
  9. ncbi request reprint Abdominal adiposity and coronary heart disease in women
    K M Rexrode
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02215, USA
    JAMA 280:1843-8. 1998
  10. ncbi request reprint Physical activity and coronary heart disease in women: is "no pain, no gain" passé?
    I M Lee
    Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
    JAMA 285:1447-54. 2001

Research Grants

  1. SEX STEROID HORMONES AND RISK OF CHD IN WOMEN
    Kathryn Rexrode; Fiscal Year: 2000
  2. SEX STEROID HORMONES AND RISK OF CHD IN WOMEN
    Kathryn Rexrode; Fiscal Year: 2001
  3. SEX STEROID HORMONES AND RISK OF CHD IN WOMEN
    Kathryn Rexrode; Fiscal Year: 2002
  4. Risk Factors for Ischemic Stroke in Women
    Kathryn Rexrode; Fiscal Year: 2009
  5. The effects of randomized, low-dose hormone therapy on mammographic density in KE
    Rulla M Tamimi; Fiscal Year: 2010
  6. Risk Factors for Ischemic Stroke in Women
    Kathryn M Rexrode; Fiscal Year: 2010
  7. Risk Factors for Ischemic Stroke in Women
    Kathryn M Rexrode; Fiscal Year: 2010

Collaborators

Detail Information

Publications79

  1. ncbi request reprint Relationship of total and abdominal adiposity with CRP and IL-6 in women
    Kathryn M Rexrode
    Center of Cardiovascular Disease Prevention, Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Ann Epidemiol 13:674-82. 2003
    ..To examine the relationship between different measures of adiposity as predictors of C-reactive protein (CRP) and interleukin-6 (IL-6) levels...
  2. pmc Telomere length and ischaemic stroke in women: a nested case-control study
    M Schurks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Eur J Neurol 20:1068-74. 2013
    ..Telomere shortening has been implicated in cardiovascular disease (CVD). However, prospective data on the association between relative telomere length (RTL) and ischaemic stroke are scarce and inconclusive...
  3. pmc Alcohol consumption and risk of stroke in women
    Monik Jimenez
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Stroke 43:939-45. 2012
    ..A lower risk of stroke with light-to-moderate alcohol intake has been suggested, but the dose response among women remains uncertain and the data in this subgroup have been sparse...
  4. ncbi request reprint Sex hormone levels and risk of cardiovascular events in postmenopausal women
    Kathryn M Rexrode
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave E, Boston, Mass 02215, USA
    Circulation 108:1688-93. 2003
    ..Despite diffuse effects of sex hormones on the cardiovascular system, few prospective studies have examined the relationship of plasma androgens and estrogens with risk of cardiovascular disease (CVD) in postmenopausal women...
  5. pmc Polymorphisms and haplotypes of the estrogen receptor-beta gene (ESR2) and cardiovascular disease in men and women
    Kathryn M Rexrode
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Clin Chem 53:1749-56. 2007
    ..Cohort studies suggest an association between variation in the estrogen receptor-alpha gene (ESR1) and cardiovascular disease (CVD), but data are lacking for the effect of variation in the estrogen receptor-beta gene (ESR2)...
  6. ncbi request reprint Abdominal and total adiposity and risk of coronary heart disease in men
    K M Rexrode
    Division of Preventive Medicine, Boston, Massachusetts 02215, USA
    Int J Obes Relat Metab Disord 25:1047-56. 2001
    ..In addition, whether the association of abdominal adiposity is independent of total adiposity as measured by body mass index (BMI) in men remains uncertain...
  7. pmc Emerging risk factors in women
    Kathryn M Rexrode
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Mass, USA
    Stroke 41:S9-11. 2010
    ....
  8. ncbi request reprint A prospective study of body mass index, weight change, and risk of stroke in women
    K M Rexrode
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    JAMA 277:1539-45. 1997
    ..To examine the associations of body mass index (BMI) and weight change with risk of stroke in women...
  9. ncbi request reprint Abdominal adiposity and coronary heart disease in women
    K M Rexrode
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02215, USA
    JAMA 280:1843-8. 1998
    ..Obesity is a well-established risk factor for coronary heart disease (CHD), but whether regional fat distribution contributes independently to risk remains unclear...
  10. ncbi request reprint Physical activity and coronary heart disease in women: is "no pain, no gain" passé?
    I M Lee
    Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
    JAMA 285:1447-54. 2001
    ..Physically active women have lower coronary heart disease (CHD) rates than inactive women. However, whether the association differs by intensity of activity or in women at high risk for CHD is unclear...
  11. ncbi request reprint Physical activity and breast cancer risk: the Women's Health Study (United States)
    I M Lee
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Cancer Causes Control 12:137-45. 2001
    ..We therefore examined physical activity and breast cancer risk in the Women's Health Study...
  12. doi request reprint Polymorphisms in advanced glycosylation end product-specific receptor (AGER) gene, insulin resistance, and type 2 diabetes mellitus
    A C Goulart
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, United States
    Clin Chim Acta 398:95-8. 2008
    ..We investigated the relationship of 3 polymorphisms (rs1800625, rs1800624 and rs2070600) in the AGER gene and their haplotypes with T2DM as well as insulin resistance...
  13. ncbi request reprint Sex hormone-binding globulin and serum testosterone are inversely associated with C-reactive protein levels in postmenopausal women at high risk for cardiovascular disease
    Hylton V Joffe
    Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, Brigham and Women s Hospital, 221 Longwood Ave, Boston, MA 02215, USA
    Ann Epidemiol 16:105-12. 2006
    ..We hypothesized that high androgens, low estradiol, and low sex hormone-binding globulin (SHBG) would be associated with high CRP in postmenopausal women...
  14. pmc Use of antidepressant medication and risk of type 2 diabetes: results from three cohorts of US adults
    A Pan
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    Diabetologia 55:63-72. 2012
    ..The results of several studies have suggested a potential positive association between use of antidepressant medication (ADM) and incident type 2 diabetes mellitus. We examined this association in three cohorts of US adults...
  15. ncbi request reprint Whole grain consumption and risk of ischemic stroke in women: A prospective study
    S Liu
    Division of Preventive Medicine, Bringham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
    JAMA 284:1534-40. 2000
    ..Although increased intake of grain products has been recommended to prevent cardiovascular disease (CVD), prospective data examining the relation of whole grain intake to risk of ischemic stroke are sparse, especially among women...
  16. doi request reprint Adherence to a DASH-style diet and risk of coronary heart disease and stroke in women
    Teresa T Fung
    Department of Nutrition, Simmons College, 300 The Fenway, and Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Arch Intern Med 168:713-20. 2008
    ..Our objective was to assess the association between a DASH-style diet adherence score and risk of coronary heart disease (CHD) and stroke in women...
  17. ncbi request reprint Maternal and paternal history of myocardial infarction and risk of cardiovascular disease in men and women
    H D Sesso
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Circulation 104:393-8. 2001
    ..Few studies have examined the effects of paternal and maternal history of myocardial infarction (MI), including age at MI, on cardiovascular disease (CVD) risk, particularly among women...
  18. pmc Association of estrogen receptor 2 gene polymorphisms with obesity in women (obesity and estrogen receptor 2 gene)
    A C Goulart
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue, 3rd Floor, Boston, MA 02215, USA
    Maturitas 62:179-83. 2009
    ..Few studies have examined the association between genetic variants of the estrogen receptor beta (ESR2) and obesity in postmenopausal women...
  19. pmc Estrogen receptor 1 gene polymorphisms and decreased risk of obesity in women
    Alessandra C Goulart
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Metabolism 58:759-64. 2009
    ..One or more copies of the C allele were associated with decreased risk of obesity in white postmenopausal women...
  20. pmc Psoriasis and risk of nonfatal cardiovascular disease in U.S. women: a cohort study
    W Q Li
    Department of Dermatology, Harvard Medical School, Boston, MA 02115, USA
    Br J Dermatol 166:811-8. 2012
    ..Psoriasis has been linked to cardiovascular comorbidities in cross-sectional studies, but evidence regarding the association between psoriasis and incident cardiovascular disease (CVD) is limited...
  21. pmc HbA1c measured in stored erythrocytes and mortality rate among middle-aged and older women
    E B Levitan
    Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, 375 Longwood Avenue, MS 443, Boston, MA 02215, USA
    Diabetologia 51:267-75. 2008
    ..We examined the association between HbA1c measured in stored erythrocytes and mortality rate in women with and without diabetes...
  22. ncbi request reprint Analgesic use and renal function in men
    K M Rexrode
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Ave, Boston, MA 02215, USA
    JAMA 286:315-21. 2001
    ..Several case-control studies suggest an association between analgesic use and increased risk of chronic renal disease, but few cohort studies have examined this association...
  23. pmc Interrelation between sex hormones and plasma sex hormone-binding globulin and hemoglobin A1c in healthy postmenopausal women
    Gabrielle Page-Wilson
    Division of Endocrinology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Metab Syndr Relat Disord 7:249-54. 2009
    ....
  24. pmc Low sex hormone-binding globulin is associated with the metabolic syndrome in postmenopausal women
    Melissa E Weinberg
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Metabolism 55:1473-80. 2006
    ..7 kg/m2. An androgenic hormone profile is associated with both the individual components of the metabolic syndrome and clustering of metabolic abnormalities in postmenopausal women...
  25. ncbi request reprint Calcium supplement intake and risk of cardiovascular disease in women
    J M Paik
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Osteoporos Int 25:2047-56. 2014
    ..In a prospective cohort study of 74,245 women in the Nurses' Health Study with 24 years of follow-up, we found no independent associations between supplemental calcium intake and risk of incident coronary heart disease (CHD) and stroke...
  26. ncbi request reprint Intake of fish and omega-3 fatty acids and risk of stroke in women
    H Iso
    Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Ave, Third Floor, Boston, MA 02215, USA
    JAMA 285:304-12. 2001
    ....
  27. pmc Sweetened beverage consumption and risk of coronary heart disease in women
    Teresa T Fung
    Department of Nutrition, Simmons College, Boston, MA 02115, USA
    Am J Clin Nutr 89:1037-42. 2009
    ..Previous studies have linked full-calorie sugar-sweetened beverages (SSBs) with greater weight gain and an increased risk of type 2 diabetes...
  28. pmc Plasma dehydroepiandrosterone and risk of myocardial infarction in women
    John H Page
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Clin Chem 54:1190-6. 2008
    ..In this study we prospectively evaluated the relationships between plasma concentrations of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA-S) and subsequent myocardial infarction in women...
  29. ncbi request reprint Nonsteroidal antiinflammatory drugs, acetaminophen, and the risk of cardiovascular events
    Andrew T Chan
    Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Circulation 113:1578-87. 2006
    ..Although randomized trials of cyclooxygenase-2 (COX-2) inhibitors have shown increased cardiovascular risk, studies of nonselective, nonsteroidal antiinflammatory drugs (NSAIDs) and acetaminophen have been inconsistent...
  30. pmc Obesity as compared with physical activity in predicting risk of coronary heart disease in women
    Tricia Y Li
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 113:499-506. 2006
    ..The comparative importance of physical inactivity and obesity as predictors of coronary heart disease (CHD) risk remains unsettled...
  31. ncbi request reprint Body mass index and risk of colorectal cancer in women (United States)
    Jennifer Lin
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215, USA
    Cancer Causes Control 15:581-9. 2004
    ..We prospectively investigated the role of BMI in colorectal cancer risk along with the modifying effects of estrogen in a large cohort from the Women's Health Study...
  32. ncbi request reprint Prospective study of sudden cardiac death among women in the United States
    Christine M Albert
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, Mass 02215 1204, USA
    Circulation 107:2096-101. 2003
    ..Nonetheless, existing data, although sparse, suggest possible gender differences in risk factors for SCD...
  33. pmc Dietary glycemic index, dietary glycemic load, blood lipids, and C-reactive protein
    Emily B Levitan
    Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Metabolism 57:437-43. 2008
    ..24, and TG = 13 mg/dL). Differences in blood lipids and CRP between extreme quintiles of dietary GI and GL were small, but may translate into a clinically meaningful difference in cardiovascular risk...
  34. ncbi request reprint Phobic anxiety and risk of coronary heart disease and sudden cardiac death among women
    Christine M Albert
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215 1204, USA
    Circulation 111:480-7. 2005
    ..To the best of our knowledge, no studies have looked at this association among women. Anxiety may influence CHD mortality by increasing the risk of ventricular arrhythmia and SCD...
  35. ncbi request reprint Analgesic use and change in kidney function in apparently healthy men
    Tobias Kurth
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Am J Kidney Dis 42:234-44. 2003
    ..Studies using a single creatinine measurement have yielded inconsistent results regarding analgesic use and kidney function...
  36. ncbi request reprint Phylloquinone intake as a marker for coronary heart disease risk but not stroke in women
    A T Erkkilä
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Eur J Clin Nutr 59:196-204. 2005
    ..To examine the feasibility of using phylloquinone intake as a marker for coronary heart disease (CHD) and stroke risk in women...
  37. doi request reprint The joint effects of physical activity and body mass index on coronary heart disease risk in women
    Amy R Weinstein
    Division of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Shapiro 1, Atrium Suite, Boston, MA 02215, USA
    Arch Intern Med 168:884-90. 2008
    ..Our objective was to study the combined association of physical activity and body mass index on CHD...
  38. ncbi request reprint Single nucleotide polymorphisms at the adiponectin locus and risk of coronary heart disease in men and women
    Tobias Pischon
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Obesity (Silver Spring) 15:2051-60. 2007
    ..The objective was to examine the association of 5 common single nucleotide polymorphisms (SNPs) at the adiponectin locus with risk of coronary heart disease (CHD) in men and women...
  39. ncbi request reprint A prospective study of trans fatty acids in erythrocytes and risk of coronary heart disease
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 115:1858-65. 2007
    ..We assessed the hypothesis that higher trans fatty acid contents in erythrocytes were associated with an elevated risk of CHD in a nested case-control study among US women...
  40. ncbi request reprint Prospective study of major dietary patterns and stroke risk in women
    Teresa T Fung
    Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02115, USA
    Stroke 35:2014-9. 2004
    ..Many foods have been suggested to influence the risk of stroke. However, no previous studies have examined the relationship between overall dietary patterns and risk of stroke...
  41. pmc Associations of the estrogen receptors 1 and 2 gene polymorphisms with the metabolic syndrome in women
    Alessandra C Goulart
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Metab Syndr Relat Disord 7:111-7. 2009
    ..Genetic variation of the estrogen receptor alpha (ESR1) and beta (ESR2) has been associated with components of the metabolic syndrome...
  42. ncbi request reprint Body mass index and the risk of stroke in men
    Tobias Kurth
    Brigham and Women s Hospital, Division of Preventive Medicine, 900 Commonwealth Ave East, Boston, MA 02215 1204, USA
    Arch Intern Med 162:2557-62. 2002
    ..Although obesity is an established risk factor for coronary heart disease, its role as a risk factor for stroke remains controversial...
  43. ncbi request reprint Peroxisome proliferator-activated receptor-gamma2 P12A polymorphism and risk of coronary heart disease in US men and women
    Tobias Pischon
    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Mass, USA
    Arterioscler Thromb Vasc Biol 25:1654-8. 2005
    ..Studies suggest that the A12 allele is associated with reduced risk of type 2 diabetes; however, data on the risk of coronary heart disease (CHD) are scarce and controversial...
  44. ncbi request reprint A prospective study of soluble tumor necrosis factor-alpha receptor II (sTNF-RII) and risk of coronary heart disease among women with type 2 diabetes
    Iris Shai
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Diabetes Care 28:1376-82. 2005
    ..Tumor necrosis factor-alpha (TNF-alpha), a cytokine secreted by adipose tissue and other cells, might play a role in insulin resistance...
  45. pmc C-reactive protein (CRP) gene polymorphisms, CRP levels, and risk of incident coronary heart disease in two nested case-control studies
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    PLoS ONE 3:e1395. 2008
    ..However, few studies have comprehensively examined six common single-nucleotide polymorphisms (SNPs) in the CRP gene, haplotypes, and plasma CRP levels with risk of coronary heart disease (CHD)...
  46. pmc Lifetime physical activity and risk of breast cancer
    I M Lee
    Division Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Br J Cancer 85:962-5. 2001
    ..47. We also separately examined physical activity at ages 12-18, 19-34, 35-49 and > or =50 years; no significant trends were observed in any age group. These data do not support a role of physical activity in preventing breast cancer...
  47. ncbi request reprint Blood concentrations of individual long-chain n-3 fatty acids and risk of nonfatal myocardial infarction
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 88:216-23. 2008
    ..Whereas dietary intake of long-chain n-3 fatty acids has been associated with risk of nonfatal myocardial infarction (MI), few studies have examined the relation for blood concentrations...
  48. pmc Mediterranean diet and incidence of and mortality from coronary heart disease and stroke in women
    Teresa T Fung
    Department of Nutrition, Simmons College, Boston, MA 02115, USA
    Circulation 119:1093-100. 2009
    ..Several studies have documented an inverse association between adherence to the Mediterranean diet and risk of coronary heart disease (CHD), but few data are available on the relationship between Mediterranean diet and risk of stroke...
  49. ncbi request reprint Fish and long-chain omega-3 fatty acid intake and risk of coronary heart disease and total mortality in diabetic women
    Frank B Hu
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, Mass 02115, USA
    Circulation 107:1852-7. 2003
    ....
  50. pmc Metabolic syndrome, inflammation, and risk of symptomatic peripheral artery disease in women: a prospective study
    David Conen
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Circulation 120:1041-7. 2009
    ..We therefore evaluated the relationship between MetS, inflammation, and incident PAD...
  51. ncbi request reprint Coffee consumption and coronary heart disease in men and women: a prospective cohort study
    Esther Lopez-Garcia
    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 113:2045-53. 2006
    ..We examined the association between long-term habitual coffee consumption and risk of coronary heart disease (CHD)...
  52. ncbi request reprint Kidney dysfunction, inflammation, and coronary events: a prospective study
    Eric L Knight
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Nephrol 15:1897-903. 2004
    ..These findings warrant further investigation in other populations...
  53. pmc Primary prevention of stroke by healthy lifestyle
    Stephanie E Chiuve
    Harvard School of Public Health, Department of Nutrition, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 118:947-54. 2008
    ..The combination of healthy lifestyle factors is associated with lower risk of coronary heart disease, diabetes, and total cardiovascular disease. Little is known about the impact of multiple lifestyle factors on the risk of stroke...
  54. pmc Longitudinal study of birth weight and adult body mass index in predicting risk of coronary heart disease and stroke in women
    Janet W Rich-Edwards
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Avenue, Boston, MA 02215, USA
    BMJ 330:1115. 2005
    ..To determine whether birth weight and adult body size interact to predict coronary heart disease in women, as has been observed for men. To determine whether birth weight and adult body size interact to predict risk of stroke...
  55. ncbi request reprint Body mass index and total and cardiovascular mortality in men with a history of cardiovascular disease
    Michael E Widlansky
    Evans Department of Medicine and Whittaker Cardiovascular Institute, Boston University School of Medicine, Boston, Mass 02215 1204, USA
    Arch Intern Med 164:2326-32. 2004
    ....
  56. ncbi request reprint Folate intake and risk of stroke among women
    Wael K Al-Delaimy
    Department of Epidemiology, Harvard School of Public Health, 665 Huntington Ave, Boston, Mass 02115, USA
    Stroke 35:1259-63. 2004
    ..We aim to assess the relation between folate intake and stroke incidence among women participating in the Nurses' Health Study...
  57. ncbi request reprint Physical exertion, exercise, and sudden cardiac death in women
    William Whang
    Cardiovascular Division, Massachusetts General Hospital, Boston, USA
    JAMA 295:1399-403. 2006
    ..Exercise is associated with a lower risk of cardiovascular events but may transiently increase the risk of ventricular arrhythmias. Its short-term and long-term associations with risk of sudden cardiac death among women are unclear...
  58. pmc Waist-height ratio as a predictor of coronary heart disease among women
    John H Page
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Epidemiology 20:361-6. 2009
    ..We compared the waist-height ratio to waist-hip ratio, waist circumference, and body mass index as predictors of subsequent coronary heart disease (CHD) in a group of predominantly postmenopausal women...
  59. pmc Association of genetic variants with the metabolic syndrome in 20,806 white women: The Women's Health Genome Study
    Alessandra C Goulart
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Am Heart J 158:257-262.e1. 2009
    ..Candidate genes associated with cardiovascular disease (CVD) represent potential risk factors for the metabolic syndrome (MetS)...
  60. ncbi request reprint Estrogen-progestin replacement therapy and breast cancer risk: the Women's Health Study (United States)
    Juliet V Porch
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Cancer Causes Control 13:847-54. 2002
    ..We therefore examined estrogen-progestin replacement therapy and breast cancer risk in the Women's Health Study...
  61. ncbi request reprint Prospective study of body mass index and risk of stroke in apparently healthy women
    Tobias Kurth
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave E, Boston, MA 02215 1204, USA
    Circulation 111:1992-8. 2005
    ..Several studies have found positive associations between body mass index (BMI) and stroke in men, but the association with stroke and its subtypes is less clear in women...
  62. pmc Joint effects of sodium and potassium intake on subsequent cardiovascular disease: the Trials of Hypertension Prevention follow-up study
    Nancy R Cook
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave East, Boston, MA 02215 1204, USA
    Arch Intern Med 169:32-40. 2009
    ..Previous studies of dose-response effects of usual sodium and potassium intake on subsequent cardiovascular disease (CVD) have largely relied on suboptimal measures of intake...
  63. ncbi request reprint Cholesterol and the risk of renal dysfunction in apparently healthy men
    Elke S Schaeffner
    Divisions of Preventive Medicine, and Aging, and Cardiovascular Disease, and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, USA
    J Am Soc Nephrol 14:2084-91. 2003
    ..5 mg/dl...
  64. pmc Excessive body iron stores are not associated with risk of coronary heart disease in women
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Nutr 138:2436-41. 2008
    ..05 (0.62, 1.77), 1.19 (0.69, 2.03), and 1.05 (0.60, 1.85; P-trend = 0.90) across quartiles. Our data do not support the hypothesis that excessive body iron stores are associated with risk of CHD...
  65. ncbi request reprint Complement factor H (Y402H) polymorphism and risk of coronary heart disease in US men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Kresge 9th Floor, Boston, MA 02115, USA
    Eur Heart J 28:1297-303. 2007
    ..We assessed the association between Y402H and risk of CHD in nested case-control studies among two large prospective cohorts of US male health professionals and female nurses...
  66. pmc Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP)
    Nancy R Cook
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMJ 334:885-8. 2007
    ..To examine the effects of reduction in dietary sodium intake on cardiovascular events using data from two completed randomised trials, TOHP I and TOHP II...
  67. pmc Depression and incident stroke in women
    An Pan
    Department of Nutrition and Epidemiology, Harvard School of Public Health, and Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Stroke 42:2770-5. 2011
    ..Depression has been associated with an increased risk of coronary heart disease, but prospective data for the association with stroke are limited...
  68. ncbi request reprint Carbohydrate intake, glycemic index, glycemic load, and dietary fiber in relation to risk of stroke in women
    Kyungwon Oh
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Epidemiol 161:161-9. 2005
    ..In addition, high consumption of cereal fiber was associated with lower risk of total and hemorrhagic stroke...
  69. ncbi request reprint Polymorphisms in the CC-chemokine receptor-2 (CCR2) and -5 (CCR5) genes and risk of coronary heart disease among US women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Atherosclerosis 186:132-9. 2006
    ..Genetic variation in CC-chemokine receptor-2 (CCR2) and -5 (CCR5), and their common haplotypes, acting through inflammatory responses, may affect atherosclerosis and risk of coronary heart disease (CHD)...
  70. pmc Coffee consumption and risk of stroke in women
    Esther Lopez-Garcia
    Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
    Circulation 119:1116-23. 2009
    ..Data on the association between coffee consumption and risk of stroke are sparse. We assessed the association between coffee consumption and the risk of stroke over 24 years of follow-up in women...
  71. ncbi request reprint Use of oral conjugated estrogen alone and risk of breast cancer
    Shumin M Zhang
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    Am J Epidemiol 165:524-9. 2007
    ..These data, like those from the Women's Health Initiative, show no significant increase in breast cancer risk with use of oral conjugated estrogen alone (0.625 mg/day), but a small increase or decrease in risk cannot be excluded...
  72. ncbi request reprint Effects of lymphotoxin-alpha gene and galectin-2 gene polymorphisms on inflammatory biomarkers, cellular adhesion molecules and risk of coronary heart disease
    Folkert W Asselbergs
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, U S A
    Clin Sci (Lond) 112:291-8. 2007
    ..05). However, no overall effect was demonstrated between LTA gene polymorphisms and risk of CHD...
  73. ncbi request reprint Postmenopausal hormone therapy and migraine headache
    Anastasia L Misakian
    University of California San Diego School of Medicine, San Diego, California, USA
    J Womens Health (Larchmt) 12:1027-36. 2003
    ..No population-based studies have examined the association between hormone therapy (HT) and migraine among postmenopausal women...
  74. doi request reprint Genetic variation of the androgen receptor and risk of myocardial infarction and ischemic stroke in women
    Kathryn M Rexrode
    Stroke 39:1590-2. 2008
    ..Some studies suggest an association between AR gene variation and risk of cardiovascular disease (CVD) in men; however, the relationship has not been examined in women...
  75. ncbi request reprint Prospective study of type 1 and type 2 diabetes and risk of stroke subtypes: the Nurses' Health Study
    Mohsen Janghorbani
    Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran
    Diabetes Care 30:1730-5. 2007
    ..The aim of this study was to examine the relationship between type 1 and type 2 diabetes and risk of stroke subtypes in women...
  76. doi request reprint Abdominal obesity and the risk of all-cause, cardiovascular, and cancer mortality: sixteen years of follow-up in US women
    Cuilin Zhang
    Epidemiology Branch, Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, 6100 Executive Blvd, Room 7B03, MSC 7510, 9000 Rockville Pike, Bethesda, MD 20892 7510, USA
    Circulation 117:1658-67. 2008
    ..However, the association of premature death resulting from these diseases with abdominal adiposity has not been widely studied, and findings are inconsistent...
  77. ncbi request reprint Postmenopausal hormone therapy and quality of life: no cause for celebration
    Kathryn M Rexrode
    JAMA 287:641-2. 2002
  78. pmc Inflammation, the metabolic syndrome, and risk of coronary heart disease in women and men
    Tobias Pischon
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558 Nuthetal, Germany
    Atherosclerosis 197:392-9. 2008
    ..This study examined whether inflammation adds to the prediction of coronary heart disease (CHD) beyond metabolic syndrome (MetS), and whether these associations differ between sexes...
  79. ncbi request reprint Are some types of hormone therapy safer than others? Lessons from the Estrogen and Thromboembolism Risk study
    Kathryn M Rexrode
    Circulation 115:820-2. 2007

Research Grants8

  1. SEX STEROID HORMONES AND RISK OF CHD IN WOMEN
    Kathryn Rexrode; Fiscal Year: 2000
    ..The investigators state that since CHD is the leading cause of death in postmenopausal women, examining the effects of endogenous hormones in postmenopausal women is an important and promising area of inquiry. ..
  2. SEX STEROID HORMONES AND RISK OF CHD IN WOMEN
    Kathryn Rexrode; Fiscal Year: 2001
    ..The investigators state that since CHD is the leading cause of death in postmenopausal women, examining the effects of endogenous hormones in postmenopausal women is an important and promising area of inquiry. ..
  3. SEX STEROID HORMONES AND RISK OF CHD IN WOMEN
    Kathryn Rexrode; Fiscal Year: 2002
    ..The investigators state that since CHD is the leading cause of death in postmenopausal women, examining the effects of endogenous hormones in postmenopausal women is an important and promising area of inquiry. ..
  4. Risk Factors for Ischemic Stroke in Women
    Kathryn Rexrode; Fiscal Year: 2009
    ..These promising biochemical and genetic markers may have implications for improving prevention strategies, enhancing treatment options and generating additional testable hypotheses for stroke research. ..
  5. The effects of randomized, low-dose hormone therapy on mammographic density in KE
    Rulla M Tamimi; Fiscal Year: 2010
    ....
  6. Risk Factors for Ischemic Stroke in Women
    Kathryn M Rexrode; Fiscal Year: 2010
    ..These promising biochemical and genetic markers may have implications for improving prevention strategies, enhancing treatment options and generating additional testable hypotheses for stroke research. ..
  7. Risk Factors for Ischemic Stroke in Women
    Kathryn M Rexrode; Fiscal Year: 2010
    ..These promising biochemical and genetic markers may have implications for improving prevention strategies, enhancing treatment options and generating additional testable hypotheses for stroke research. ..