Rinaa S Punglia

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Should a sentinel node biopsy be performed in patients with high-risk breast cancer?
    Kenneth D Westover
    Harvard Radiation Oncology Program, Boston, MA 02115, USA
    Int J Breast Cancer 2011:973245. 2011
  2. ncbi request reprint Prostate-specific antigen velocity and the detection of gleason score 7 to 10 prostate cancer
    Rinaa S Punglia
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Cancer 110:1973-8. 2007
  3. pmc Pharmacogenomic variation of CYP2D6 and the choice of optimal adjuvant endocrine therapy for postmenopausal breast cancer: a modeling analysis
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, 44 Binney St, Boston, MA 02115, USA
    J Natl Cancer Inst 100:642-8. 2008
  4. ncbi request reprint The impact of tumor progesterone receptor status on optimal adjuvant endocrine therapy for postmenopausal patients with early-stage breast cancer: a decision analysis
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer 106:2576-82. 2006
  5. ncbi request reprint Optimizing adjuvant endocrine therapy in postmenopausal women with early-stage breast cancer: a decision analysis
    Rinaa S Punglia
    Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 23:5178-87. 2005
  6. doi request reprint Accelerated partial breast irradiation using brachytherapy for breast cancer: patterns in utilization and guideline concordance
    Jona A Hattangadi
    Harvard Radiation Oncology Program, Boston, MA, USA
    J Natl Cancer Inst 104:29-41. 2012
  7. pmc Use of stereotactic radiosurgery for brain metastases from non-small cell lung cancer in the United States
    Lia M Halasz
    Department of Radiation Oncology, University of Washington, Seattle, Washington, USA
    Int J Radiat Oncol Biol Phys 85:e109-16. 2013
  8. pmc Cost effectiveness and screening interval of lipid screening in Hodgkin's lymphoma survivors
    Aileen B Chen
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, MA 02115, USA
    J Clin Oncol 27:5383-9. 2009
  9. pmc Partial breast irradiation versus whole breast radiotherapy for early-stage breast cancer: a decision analysis
    David J Sher
    Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 70:469-76. 2008
  10. pmc Partial-breast irradiation versus whole-breast irradiation for early-stage breast cancer: a cost-effectiveness analysis
    David J Sher
    Harvard Radiation Oncology Program, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 74:440-6. 2009

Research Grants

Detail Information

Publications35

  1. pmc Should a sentinel node biopsy be performed in patients with high-risk breast cancer?
    Kenneth D Westover
    Harvard Radiation Oncology Program, Boston, MA 02115, USA
    Int J Breast Cancer 2011:973245. 2011
    ..This tool may be useful in identifying patients who should have expanded upfront exploration of the axilla or comprehensive axillary irradiation...
  2. ncbi request reprint Prostate-specific antigen velocity and the detection of gleason score 7 to 10 prostate cancer
    Rinaa S Punglia
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Cancer 110:1973-8. 2007
    ..In this study, the authors evaluated whether PSA velocity was associated with prostate cancer detection and grade at diagnosis after adjusting for established predictors...
  3. pmc Pharmacogenomic variation of CYP2D6 and the choice of optimal adjuvant endocrine therapy for postmenopausal breast cancer: a modeling analysis
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, 44 Binney St, Boston, MA 02115, USA
    J Natl Cancer Inst 100:642-8. 2008
    ....
  4. ncbi request reprint The impact of tumor progesterone receptor status on optimal adjuvant endocrine therapy for postmenopausal patients with early-stage breast cancer: a decision analysis
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer 106:2576-82. 2006
    ..However, the optimal sequencing of AIs and tamoxifen as adjuvant therapy is not known and may differ for biologic subsets of cancers...
  5. ncbi request reprint Optimizing adjuvant endocrine therapy in postmenopausal women with early-stage breast cancer: a decision analysis
    Rinaa S Punglia
    Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 23:5178-87. 2005
    ..Options include the antiestrogen tamoxifen, estrogen deprivation with aromatase inhibitors, and sequential therapy with tamoxifen and then an aromatase inhibitor...
  6. doi request reprint Accelerated partial breast irradiation using brachytherapy for breast cancer: patterns in utilization and guideline concordance
    Jona A Hattangadi
    Harvard Radiation Oncology Program, Boston, MA, USA
    J Natl Cancer Inst 104:29-41. 2012
    ..We evaluated patterns of APBIb use with respect to 2009 American Society for Radiation Oncology consensus guidelines (ASTRO-G) in a population-based cohort...
  7. pmc Use of stereotactic radiosurgery for brain metastases from non-small cell lung cancer in the United States
    Lia M Halasz
    Department of Radiation Oncology, University of Washington, Seattle, Washington, USA
    Int J Radiat Oncol Biol Phys 85:e109-16. 2013
    ..The indications for treatment of brain metastases from non-small cell lung cancer (NSCLC) with stereotactic radiosurgery (SRS) remain controversial. We studied patterns, predictors, and cost of SRS use in elderly patients with NSCLC...
  8. pmc Cost effectiveness and screening interval of lipid screening in Hodgkin's lymphoma survivors
    Aileen B Chen
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, MA 02115, USA
    J Clin Oncol 27:5383-9. 2009
    ..We evaluated the cost effectiveness of lipid screening in survivors of HL and compared different screening intervals...
  9. pmc Partial breast irradiation versus whole breast radiotherapy for early-stage breast cancer: a decision analysis
    David J Sher
    Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 70:469-76. 2008
    ..To compare the quality-adjusted life expectancy between women treated with partial breast irradiation (PBI) vs. whole breast radiotherapy (WBRT) for estrogen receptor-positive early-stage breast cancer...
  10. pmc Partial-breast irradiation versus whole-breast irradiation for early-stage breast cancer: a cost-effectiveness analysis
    David J Sher
    Harvard Radiation Oncology Program, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 74:440-6. 2009
    ..We aim to determine the incremental cost-effectiveness of PBI compared with whole-breast radiation therapy (WBRT) for estrogen receptor-positive postmenopausal women treated for early-stage breast cancer...
  11. ncbi request reprint Radiation therapy after mastectomy between 1991 and 1999 in elderly women: response to clinical trial information
    Rinaa S Punglia
    Department of Radiation Oncology and Center for Outcomes and Policy Research, Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 24:3474-82. 2006
    ..We sought to study the receipt of PMRT in elderly women in this period, using a population-based cohort of women with breast cancer...
  12. doi request reprint Margin status and the risk of local recurrence in patients with early-stage breast cancer treated with breast-conserving therapy
    Andrea L Russo
    Harvard Radiation Oncology Program, Boston, MA 02215, USA
    Breast Cancer Res Treat 140:353-61. 2013
    ..Additional studies are needed to confirm this finding. ..
  13. pmc Radiation therapy for ductal carcinoma in situ: a decision analysis
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 118:603-11. 2012
    ..The benefit of adding radiation therapy after excision of ductal carcinoma in situ (DCIS) is widely debated. Randomized clinical trials are underpowered to delineate long-term outcomes after radiation...
  14. ncbi request reprint Radiation therapy plus tamoxifen versus tamoxifen alone after breast-conserving surgery in postmenopausal women with stage I breast cancer: a decision analysis
    Rinaa S Punglia
    Joint Center for Radiation Therapy, Harvard Medical School, Boston, MA, USA
    J Clin Oncol 21:2260-7. 2003
    ....
  15. pmc Pathologic characteristics of second breast cancers after breast conservation for ductal carcinoma in situ
    Nils D Arvold
    Harvard Radiation Oncology Program, Harvard Medical School, Boston, Massachusetts, USA
    Cancer 118:6022-30. 2012
    ..The authors described the characteristics of SBC and examined associations between the pathologic features of SBC and index DCIS cases...
  16. pmc Impact of interval from breast conserving surgery to radiotherapy on local recurrence in older women with breast cancer: retrospective cohort analysis
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    BMJ 340:c845. 2010
    ..To determine if the length of interval between breast conserving surgery and start of radiotherapy affects local recurrence and to identify factors that might be associated with delay in older women with breast cancer...
  17. ncbi request reprint Cost-effectiveness analysis of computerized tomography in the routine follow-up of patients after primary treatment for Hodgkin's disease
    Beverly A Guadagnolo
    Joint Center for Radiation Therapy Harvard Radiation Oncology Program, Harvard School of Public Health, Harvard University, Boston, MA 02215, USA
    J Clin Oncol 24:4116-22. 2006
    ..To estimate the clinical benefits and cost effectiveness of computed tomography (CT) in the follow-up of patients with complete response (CR) after treatment for Hodgkin's disease (HD)...
  18. pmc Influence of year of diagnosis, patient age, and sociodemographic status on recommending adjuvant radiation treatment for stage I testicular seminoma
    Karen E Hoffman
    Department of Radiation Oncology, Brigham and Women s Hospital, 375 Longwood Ave, Boston, MA 02115, USA
    J Clin Oncol 26:3937-42. 2008
    ..This study evaluated ART trends in the United States and the impact of clinical and sociodemographic factors on ART recommendations...
  19. ncbi request reprint Impact of age, benign prostatic hyperplasia, and cancer on prostate-specific antigen level
    Rinaa S Punglia
    Department of Radiation Oncology, Brigham and Women s Hospital, Boston, MA 02115, USA
    Cancer 106:1507-13. 2006
    ..Correcting for verification bias, the means and variances of PSA values were estimated in specific clinical scenarios...
  20. doi request reprint Trade-offs associated with axillary lymph node dissection with breast irradiation versus breast irradiation alone in patients with a positive sentinel node in relation to the risk of non-sentinel node involvement: implications of ACOSOG Z0011
    Monica S Krishnan
    Harvard Radiation Oncology Program, Boston, MA, USA
    Breast Cancer Res Treat 138:205-13. 2013
    ..6 % or lymphedema risk with ALND is under 10 %. Patients eligible for Z0011 but at a higher risk of residual nodal disease following BCS and positive SLNB may benefit from ALND + BRT, rather than BRT alone...
  21. doi request reprint Impact of margin status on local recurrence after mastectomy for ductal carcinoma in situ
    Stephanie K Childs
    Harvard Radiation Oncology Program, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 85:948-52. 2013
    ..To examine the rate of local recurrence according to the margin status for patients with pure ductal carcinoma in situ (DCIS) treated by mastectomy...
  22. pmc Factors associated with guideline-concordant use of radiotherapy after mastectomy in the national comprehensive cancer network
    Rinaa S Punglia
    Dana Farber Cancer Institute, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 72:1434-40. 2008
    ....
  23. ncbi request reprint Local therapy and survival in breast cancer
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    N Engl J Med 356:2399-405. 2007
  24. ncbi request reprint Personalized medicine in breast cancer: tamoxifen, endoxifen, and CYP2D6 in clinical practice
    Kathryn J Ruddy
    Dana Farber Cancer Institute, 450 Brookline Ave, Boston, MA, 02215, USA
    Breast Cancer Res Treat 141:421-7. 2013
    ....
  25. doi request reprint Treatment of ductal carcinoma in situ after excision: would a prophylactic paradigm be more appropriate?
    Rinaa S Punglia
    Affiliations of authors Department of Radiation Oncology RSP and Division of Medical Oncology JCW, Dana Farber Cancer Institute, Boston, MA Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA SJS
    J Natl Cancer Inst 105:1527-33. 2013
    ....
  26. ncbi request reprint Effect of verification bias on screening for prostate cancer by measurement of prostate-specific antigen
    Rinaa S Punglia
    Joint Center for Radiation Therapy, Harvard Medical School, Boston, USA
    N Engl J Med 349:335-42. 2003
    ..We assessed the screening characteristics of the prostate-specific antigen (PSA) measurement after correction for verification bias...
  27. doi request reprint Improved outcomes of breast-conserving therapy for patients with ductal carcinoma in situ
    Lia M Halasz
    Harvard Radiation Oncology Program, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 82:e581-6. 2012
    ..We sought to determine the following: LR rates with this more modern approach; the relation between LR and HER-2 status; and clinical and pathologic factors associated with HER-2(+) DCIS...
  28. pmc Adjuvant therapy for elderly patients with resected gastric adenocarcinoma: population-based practices and treatment effectiveness
    Karen E Hoffman
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Cancer 118:248-57. 2012
    ..A study was undertaken to determine the survival benefit of postoperative chemoradiation therapy for elderly patients with resected gastric adenocarcinoma...
  29. pmc Effect of very small tumor size on cancer-specific mortality in node-positive breast cancer
    Jennifer Y Wo
    Dana Farber Cancer Institute Brigham and Women s Hospital, Boston, MA 02115, USA
    J Clin Oncol 29:2619-27. 2011
    ..In particular, we evaluated whether very small tumor size may predict for increased BCSM relative to larger tumors in patients with extensive LN involvement...
  30. pmc Modeling the effectiveness of initial management strategies for ductal carcinoma in situ
    Djøra I Soeteman
    Center for Health Decision Science, Department of Health Policy and Management, Harvard School of Public Health, Boston, MA 02115, USA
    J Natl Cancer Inst 105:774-81. 2013
    ..We sought to quantify the tradeoffs among alternative management strategies for DCIS with respect to disease outcomes and breast preservation...
  31. doi request reprint Cost-effectiveness analysis of stereotactic body radiotherapy and radiofrequency ablation for medically inoperable, early-stage non-small cell lung cancer
    David J Sher
    Department of Radiation Oncology, Dana Farber Cancer Institute Brigham and Women s Hospital, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 81:e767-74. 2011
    ..Radiofrequency ablation (RFA) has also been investigated as a less costly, single-day therapy that thermally ablates small, peripheral tumors. The cost-effectiveness of these three techniques has never been compared...
  32. ncbi request reprint Effect of distance to radiation treatment facility on use of radiation therapy after mastectomy in elderly women
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 66:56-63. 2006
    ..We sought to study the effect of distance to the nearest radiation treatment facility on the use of postmastectomy radiation therapy (PMRT) in elderly women...
  33. ncbi request reprint Variability among breast radiation oncologists in delineation of the postsurgical lumpectomy cavity
    Daniel M Landis
    Joint Center for Radiation Therapy Residency Training Program, Harvard Medical School, Brigham and Women s Hospital, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 67:1299-308. 2007
    ..We examined the interobserver variability in delineation of the lumpectomy cavity among four academic radiation oncologists who specialize in the treatment of breast cancer...
  34. ncbi request reprint Operating characteristics of prostate-specific antigen and verification bias
    Rinaa S Punglia
    JAMA 294:2698; author reply 2698-9. 2005
  35. ncbi request reprint Integrating surgery and radiotherapy to reduce toxicity while maintaining local control for breast cancer: a fine balance
    Rinaa S Punglia
    Ann Surg Oncol 9:526-8. 2002

Research Grants2

  1. Decision-making regarding radiation therapy in breast cancer"
    RINAA PUNGLIA; Fiscal Year: 2007
    ..The proposed combined education and research program, in addition to strong mentorship, will provide the candidate with the skills and experience necessary for a career as an independent outcomes researcher in breast cancer. ..