Research Topics
| M B PitmanSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Publications
Reducing or eliminating use of the category of atypical squamous cells of undetermined significance decreases the diagnostic accuracy of the Papanicolaou smearMartha Bishop Pitman
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Cancer 96:128-34. 2002..In the current study, the authors investigated the impact of reducing and eliminating this category on the sensitivity and predictive values for detecting squamous intraepithelial lesions (SILs)...- Endoscopic ultrasound-guided fine needle aspiration cytology of the pancreas: a morphological and multimodal approach to the diagnosis of solid and cystic mass lesionsM B Pitman
Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
Cytopathology 18:331-47. 2007..This review focuses on the multimodal approach at the Massachusetts General Hospital that utilizes clinical, cytological, radiological and ancillary studies in rendering a final cytological diagnosis... 
Prospective analysis of atypical epithelial cells as a high-risk cytologic feature for malignancy in pancreatic cystsMartha B Pitman
Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 01907, USA
Cancer Cytopathol 121:29-36. 2013..The objective of the current study was to assess the accuracy of AECs in predicting malignancy in pancreatic cysts...- Hepatocyte paraffin 1 antibody does not distinguish primary ovarian tumors with hepatoid differentiation from metastatic hepatocellular carcinomaMartha B Pitman
James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Int J Gynecol Pathol 23:58-64. 2004..Hepatocyte paraffin 1, however, is not useful in distinguishing metastatic hepatocellular carcinoma from primary ovarian hepatoid carcinoma or hepatoid yolk sac tumor... - Techniques for thyroid FNA: a synopsis of the National Cancer Institute Thyroid Fine-Needle Aspiration State of the Science ConferenceMartha Bishop Pitman
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Diagn Cytopathol 36:407-24. 2008..http://thyroidfna.cancer.gov/pages/info/agenda/).. - Cytological and cyst fluid analysis of small (< or =3 cm) branch duct intraductal papillary mucinous neoplasms adds value to patient management decisionsMartha Bishop Pitman
James Homer Wright Pathology Laboratories and Cytopathology Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Pancreatology 8:277-84. 2008..The aim of our study was to compare this proposed algorithm to one that incorporates cytology with less than malignant epithelial cells and cyst fluid carcinoembryonic antigen (CEA)... - Pancreatic cysts: preoperative diagnosis and clinical managementMartha Bishop Pitman
Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Cancer Cytopathol 118:1-13. 2010..High CEA level supports a mucinous cyst, as do KRAS mutation and good quality DNA levels. KRAS mutation and multiple LOH support malignancy... - High-grade atypical epithelial cells in pancreatic mucinous cysts are a more accurate predictor of malignancy than "positive" cytologyMartha Bishop Pitman
Department of Pathology, The James Homer Wright Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Cancer Cytopathol 118:434-40. 2010..In the current study, the authors hypothesized that a cytological threshold of high-grade atypical epithelial cells (AEC) is a more accurate predictor of malignancy... - The fine-needle aspiration biopsy cytology of pancreatoblastomaMartha Bishop Pitman
The James Homer Wright Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Diagn Cytopathol 31:402-6. 2004.... - The clinical application and cost analysis of fine-needle aspiration biopsy in the diagnosis of mass lesions in sarcoidosisR Tambouret
James Homer Wright Laboratories of the General Hospital and the Department of Pathology, Harvard Medical School, Boston, MA 02114, USA
Chest 117:1004-11. 2000..We analyzed the utility and relative cost-effectiveness of fine-needle aspiration biopsy (FNAB) in the clinical investigation of patients with both suspected and unsuspected sarcoidosis... - Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlationsDavid C Wilbur
Department of Pathology, James Homer Wright Pathology Laboratories, Massachusetts General Hospital, and the Department of Pathology, Harvard Medical School, Boston, MA 02114, USA
Arch Pathol Lab Med 133:1949-53. 2009..Before implementation, technical issues, pathologist adaptability, and morphologic pitfalls must be well characterized... - Endoscopic ultrasound guided fine needle aspiration biopsy of autoimmune pancreatitis: diagnostic criteria and pitfallsVikram Deshpande
Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
Am J Surg Pathol 29:1464-71. 2005.... - Cytologic diagnosis of dysplasia in the alimentary tractRosemary Tambouret
Department of Pathology, Massachusetts General Hospital, Boston 02114, USA
Semin Diagn Pathol 19:38-47. 2002.... - Adenosquamous carcinoma of the pancreas: cytologic features in 14 casesAliyah Rahemtullah
The James Homer Wright Pathology Laboratories and Cytopathology Laboratory at the Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Cancer 99:372-8. 2003..In the current study, the authors describe their experience with the fine-aspiration biopsy (FNAB) diagnosis of ASCa and characterize cytologic features in 14 cases... - Low-density pheochromocytoma on CT: a mimicker of adrenal adenomaMichael A Blake
Department of Radiology, Division of Abdominal Imaging and Intervention, Massachusetts General Hospital, 55 Fruit St, White 270, Boston, MA 02114, USA
AJR Am J Roentgenol 181:1663-8. 2003..The purpose of our study was to determine if pheochromocytomas could be confused with adenomas by virtue of their attenuation values on unenhanced CT... - Serous cystadenoma of the pancreas: limitations and pitfalls of endoscopic ultrasound-guided fine-needle aspiration biopsyNicole A Belsley
Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Cancer 114:102-10. 2008..In the current study, the authors evaluated the diagnostic sensitivity of endoscopic ultrasound (EUS)-guided fine-needle aspiration biopsy (FNAB) and cross-sectional imaging for SCA... - Cytologic features of clear cell sarcoma (malignant melanoma) of soft parts: a study of fine-needle aspirates and exfoliative specimensAndrew J Creager
Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
Am J Clin Pathol 117:217-24. 2002..Owing to the rarity of CCS, the diagnosis on cytologic smears is extremely difficult and is aided substantially by pertinent clinical data. The diagnosis can be made conclusively by.. - An algorithmic approach to the diagnosis of pancreatic neoplasmsDavid S Klimstra
Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA
Arch Pathol Lab Med 133:454-64. 2009..The pancreas gives rise to an array of distinct neoplasms that can be solid, cystic, or intraductal and can recapitulate the various lines of differentiation present in the normal gland... - Fine-needle aspiration biopsy of Hurthle cell lesions of the thyroid gland: A cytomorphologic study of 139 cases with statistical analysisDanielle D Elliott
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 108:102-9. 2006.... - Cytomorphology and B72.3 labeling of benign and malignant ductal epithelium in pancreatic lesions compared to gastrointestinal epitheliumRanjana S Nawgiri
Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA
Diagn Cytopathol 35:300-5. 2007.... - Significance of endothelium in the fine-needle aspiration biopsy diagnosis of hepatocellular carcinomaM B Pitman
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
Diagn Cytopathol 12:208-14. 1995..We conclude that the presence of endothelium, at least focally in either one or both distinctive patterns, is highly sensitive and specific for HCC and aides in distinguishing it from benign hepatocytic lesions, CC, and metastases... - Malignant melanoma with a myxoid stroma: a diagnostic pitfall on fine-needle aspiration biopsyD Elliott
Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Diagn Cytopathol 25:185-90. 2001..Although HMB-45 is typically negative in both tumors, S100 should be strongly positive in myxoid MM and only focal in MPNST... - Molecular analysis of pancreatic cyst fluid: a comparative analysis with current practice of diagnosisJian Shen
James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Cancer 117:217-27. 2009.... - Cytomorphology of gastric and duodenal epithelium and reactivity to B72.3: a baseline for comparison to pancreatic lesions aspirated by EUS-FNABJulie A Nagle
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Diagn Cytopathol 33:381-6. 2005..These baseline characteristics provide a template for assessing mucin and epithelial GM and DM contamination on pancreatic EUS-FNAB specimens... - Automated algorithm for differentiation of human breast tissue using low coherence interferometry for fine needle aspiration biopsy guidanceBRIAN D GOLDBERG
Massachusetts General Hospital, Wellman Center for Photomedicine, 40 Blossom Street, Boston, Massachusetts 02114, USA
J Biomed Opt 13:014014. 2008..1% (89.7 to 99.9) sensitivity and 82.4% (65.5 to 93.2) specificity where the numbers in parentheses represent the 95% confidence intervals. These results suggest that LCI can be used to determine tissue type and guide FNAB of the breast... - EUS-guided FNA for the diagnosis of GI stromal cell tumors: sensitivity and cytologic yieldPaul S Sepe
Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Gastrointest Endosc 70:254-61. 2009..Studies to date evaluating the sensitivity of EUS-FNA for the diagnosis of GI stromal cell tumors (GIST) have been small, and few have relied on surgical histologic diagnosis as the reference standard... - Fine-needle aspiration biopsy in the diagnosis and classification of primary and recurrent lymphoma: a retrospective analysis of the utility of cytomorphology and flow cytometryH Y Dong
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Mod Pathol 14:472-81. 2001..A mere cytological diagnosis of positive for lymphoma is no longer acceptable if FNAB is to become an independent diagnostic tool for lymphoma... - The negative predicative value of breast fine-needle aspiration biopsy: the Massachusetts General Hospital experienceStephen K Lau
Department of Pathology, Grady Memorial Hospital, Emory University Medical School, Atlanta, Georgia, USA
Breast J 10:487-91. 2004..However, in the setting of a triple-negative test, the NPV in our patient population was 100%, reassuring the patient and clinician that clinical follow-up and not surgical intervention was sufficient for proper patient care... - Choriocarcinoma involving the pancreas as first manifestation of a metastatic regressing mixed testicular germ cell tumorLan Wang
Department of Pathology, Harvard Medical School, Boston, MA 02114, USA
Mod Pathol 17:1573-80. 2004..Subsequent resection of the testicular mass confirmed the presence of a cystic and scarring (regressing) mixed germ cell tumor but without evidence of choriocarcinoma... - Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 3-2005. A 14-year-old boy with recent slowing of growth and delayed pubertyEsther J Israel
Department of Pediatrics, the Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, USA
N Engl J Med 352:393-403. 2005 - Rare benign and malignant appendiceal lesions: spectrum of computed tomography findings with pathologic correlationYi-You Chiou
Department of Radiology, Massachusetts General Hospital, and Harvard Medical School, Boston, MA 02114, USA
J Comput Assist Tomogr 27:297-306. 2003..Radiologists need to understand the full spectrum of appendiceal abnormalities, their underlying pathologic changes, and associated CT imaging findings... - Bronchogenic cyst of the gastric fundus presenting as a gastrointestinal stromal tumorNicolas Melo
Harvard Medical School, The Massachusetts General Hospital, Boston, Massachusetts 02114, USA
J Laparoendosc Adv Surg Tech A 15:163-5. 2005..The importance of this case is that it demonstrates a rare yet essential component to the differential diagnosis of lesions of the stomach... - Intraductal papillary mucinous neoplasm of the pancreas: cytologic features predict histologic gradePaul J Michaels
James Homer Wright Pathology Laboratories and Cytopathology Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Cancer 108:163-73. 2006..Necrosis was the only feature found to be strongly suggestive of invasion...