Michael H Picard

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Echocardiographic predictors of survival and response to early revascularization in cardiogenic shock
    Michael H Picard
    Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    Circulation 107:279-84. 2003
  2. doi request reprint Assessment of left ventricular function by echocardiography: a technique in evolution
    Michael H Picard
    Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Am Soc Echocardiogr 21:14-21. 2008
  3. pmc Assessment of echocardiography and biomarkers for the extended prediction of cardiotoxicity in patients treated with anthracyclines, taxanes, and trastuzumab
    Heloisa Sawaya
    Cardiac Ultrasound Laboratory and Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Circ Cardiovasc Imaging 5:596-603. 2012
  4. ncbi request reprint A randomized, double-blind, placebo-controlled study of the safety and efficacy of intravenous MCC-135 as an adjunct to primary percutaneous coronary intervention in patients with acute myocardial infarction: Evaluation of MCC-135 for left ventricular sal
    Ik Kyung Jang
    Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Am Heart J 155:113.e1-8. 2008
  5. ncbi request reprint Cardiomyocyte-specific overexpression of nitric oxide synthase 3 prevents myocardial dysfunction in murine models of septic shock
    Fumito Ichinose
    Department of Anesthesia and Critical Care, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    Circ Res 100:130-9. 2007
  6. ncbi request reprint Disruption of nitric oxide synthase 3 protects against the cardiac injury, dysfunction, and mortality induced by doxorubicin
    Tomas G Neilan
    Cardiovascular Research Center, Division of Cardiology, Massachusetts General Hospital, Charlestown, MA, USA
    Circulation 116:506-14. 2007
  7. ncbi request reprint Progressive nature of chronic mitral regurgitation and the role of tissue Doppler-derived indexes
    Tomas G Neilan
    Cardiac Ultrasound Laboratory, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02115 2696, USA
    Am J Physiol Heart Circ Physiol 294:H2106-11. 2008
  8. ncbi request reprint Left ventricular lead electrical delay predicts response to cardiac resynchronization therapy
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Heart Rhythm 3:1285-92. 2006
  9. doi request reprint Impact of aortic regurgitation after transcatheter aortic valve implantation: results from the REVIVAL trial
    Kibar Yared
    Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    JACC Cardiovasc Imaging 5:469-77. 2012
  10. ncbi request reprint Preload dependency of left ventricular torsion: the impact of normal saline infusion
    Rory B Weiner
    Division of Cardiology, Massachusetts General Hospital, Boston, Mass, USA
    Circ Cardiovasc Imaging 3:672-8. 2010

Detail Information

Publications111 found, 100 shown here

  1. ncbi request reprint Echocardiographic predictors of survival and response to early revascularization in cardiogenic shock
    Michael H Picard
    Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    Circulation 107:279-84. 2003
    ....
  2. doi request reprint Assessment of left ventricular function by echocardiography: a technique in evolution
    Michael H Picard
    Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Am Soc Echocardiogr 21:14-21. 2008
    ..The future will undoubtedly see a new method of clinical cardiology care but with continued evolution, echocardiographic quantitation of LV function should remain a vital part of patient care...
  3. pmc Assessment of echocardiography and biomarkers for the extended prediction of cardiotoxicity in patients treated with anthracyclines, taxanes, and trastuzumab
    Heloisa Sawaya
    Cardiac Ultrasound Laboratory and Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Circ Cardiovasc Imaging 5:596-603. 2012
    ..The present study investigates whether early alterations of myocardial strain and blood biomarkers predict incident cardiotoxicity in patients with breast cancer during treatment with anthracyclines, taxanes, and trastuzumab...
  4. ncbi request reprint A randomized, double-blind, placebo-controlled study of the safety and efficacy of intravenous MCC-135 as an adjunct to primary percutaneous coronary intervention in patients with acute myocardial infarction: Evaluation of MCC-135 for left ventricular sal
    Ik Kyung Jang
    Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Am Heart J 155:113.e1-8. 2008
    ....
  5. ncbi request reprint Cardiomyocyte-specific overexpression of nitric oxide synthase 3 prevents myocardial dysfunction in murine models of septic shock
    Fumito Ichinose
    Department of Anesthesia and Critical Care, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    Circ Res 100:130-9. 2007
    ....
  6. ncbi request reprint Disruption of nitric oxide synthase 3 protects against the cardiac injury, dysfunction, and mortality induced by doxorubicin
    Tomas G Neilan
    Cardiovascular Research Center, Division of Cardiology, Massachusetts General Hospital, Charlestown, MA, USA
    Circulation 116:506-14. 2007
    ....
  7. ncbi request reprint Progressive nature of chronic mitral regurgitation and the role of tissue Doppler-derived indexes
    Tomas G Neilan
    Cardiac Ultrasound Laboratory, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02115 2696, USA
    Am J Physiol Heart Circ Physiol 294:H2106-11. 2008
    ..001). Therefore, in a chronic model of MR, serial echocardiography demonstrated that MR begets MR and that those TD-derived indexes that initially increased post-MR decreased to baseline before any changes in LV ejection fraction...
  8. ncbi request reprint Left ventricular lead electrical delay predicts response to cardiac resynchronization therapy
    Jagmeet P Singh
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Heart Rhythm 3:1285-92. 2006
    ....
  9. doi request reprint Impact of aortic regurgitation after transcatheter aortic valve implantation: results from the REVIVAL trial
    Kibar Yared
    Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    JACC Cardiovasc Imaging 5:469-77. 2012
    ....
  10. ncbi request reprint Preload dependency of left ventricular torsion: the impact of normal saline infusion
    Rory B Weiner
    Division of Cardiology, Massachusetts General Hospital, Boston, Mass, USA
    Circ Cardiovasc Imaging 3:672-8. 2010
    ..The net difference between systolic apical counterclockwise rotation and basal clockwise rotation is left ventricular torsion (LVT). Although LVT is altered in various cardiac diseases, determinants of LVT are incompletely understood...
  11. doi request reprint Significance of electrocardiographic right bundle branch block in trained athletes
    Jonathan H Kim
    Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Am J Cardiol 107:1083-9. 2011
    ....
  12. pmc A short duration of high-fat diet induces insulin resistance and predisposes to adverse left ventricular remodeling after pressure overload
    Michael J Raher
    Cardiac Ultrasound Laboratory, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA 02114, USA
    Am J Physiol Heart Circ Physiol 295:H2495-502. 2008
    ..These metabolic changes are accompanied by increased LV remodeling and dysfunction after TAC, highlighting the impact of insulin resistance in the development of pressure-overload-induced heart failure...
  13. pmc Long-term anabolic-androgenic steroid use is associated with left ventricular dysfunction
    Aaron L Baggish
    Division of Cardiology, Massachusetts General Hospital, and Department of Medicine, Harvard Medical School, Boston, Mass 02114, USA
    Circ Heart Fail 3:472-6. 2010
    ..We compared cardiac parameters in weightlifters reporting long-term AAS use to those in otherwise similar weightlifters without prior AAS exposure...
  14. ncbi request reprint Usefulness of a novel "response score" to predict hemodynamic and clinical outcome from cardiac resynchronization therapy
    E Kevin Heist
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 97:1732-6. 2006
    ..0001). Kaplan-Meier analysis associated a higher response score with improved 12-month event-free survival after CRT implantation (p=0.0019)...
  15. pmc Predictors of sustained ventricular arrhythmias in cardiac resynchronization therapy
    Daniel J Friedman
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA 02114, USA
    Circ Arrhythm Electrophysiol 5:762-72. 2012
    ..Patients undergoing cardiac resynchronization therapy (CRT) are at high risk for ventricular arrhythmias (VAs), and risk stratification in this population remains poor...
  16. ncbi request reprint Ventricular arrhythmia following alcohol septal ablation for obstructive hypertrophic cardiomyopathy
    Peter A Noseworthy
    Cardiology Division, Massachusetts General Hospital, Boston, MA, USA
    Am J Cardiol 104:128-32. 2009
    ..In conclusion, ASA was performed in patients with highly symptomatic, drug-refractory hypertrophic cardiomyopathy with no mortality attributable to SCD and an annual rate of VT/VF, cardiac arrest, or appropriate ICD therapy of 4.9%/year...
  17. pmc Galectin-3, cardiac structure and function, and long-term mortality in patients with acutely decompensated heart failure
    Ravi V Shah
    Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 32 Fruit Street, Yawkey 5984, Boston, MA 02114, USA
    Eur J Heart Fail 12:826-32. 2010
    ..To determine the relationship between galectin-3 concentrations and cardiac structure in patients with acute dyspnoea, and to evaluate the impact of galectin-3 independent of echocardiographic measurements on long-term mortality...
  18. ncbi request reprint Pressure overload-induced LV hypertrophy and dysfunction in mice are exacerbated by congenital NOS3 deficiency
    Fumito Ichinose
    Dept of Anesthesia and Critical Care, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    Am J Physiol Heart Circ Physiol 286:H1070-5. 2004
    ..These results suggest that the absence of NOS3 augments LV dysfunction and remodeling in a murine model of chronic pressure overload...
  19. ncbi request reprint Myocardial adaptation and efficiency in response to intensive physical training in elite speedskaters
    Kian Keong Poh
    Cardiac Ultrasound Laboratory, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02115 2696, USA
    Int J Cardiol 126:346-51. 2008
    ..Studies utilizing conventional and tissue Doppler echocardiographic studies in highly competitive elite athletes whose training includes both aerobic and weight training are limited...
  20. pmc Usefulness of hemoglobin A(1c) to predict outcome after cardiac resynchronization therapy in patients with diabetes mellitus and heart failure
    Ravi V Shah
    Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 110:683-8. 2012
    ..In conclusion, although the presence of diabetes, independent of other variables, increases the hazard of worse outcomes after CRT, there is additional risk conferred by insulin use and suboptimal peri-implantation glycemic control...
  21. doi request reprint The feasibility, diagnostic yield, and learning curve of portable echocardiography for out-of-hospital cardiovascular disease screening
    Rory B Weiner
    Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Am Soc Echocardiogr 25:568-75. 2012
    ..Data documenting the feasibility, yield, and logistical considerations of out-of-hospital TTE for preparticipation evaluation of athletes are sparse...
  22. doi request reprint Impact of segmental left ventricle lead position on cardiac resynchronization therapy outcomes
    Faisal M Merchant
    Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Heart Rhythm 7:639-44. 2010
    ..The optimal pacing site for cardiac resynchronization therapy (CRT) is along the left ventricle (LV) lateral or posterolateral wall. However, little is known about the impact of segmental pacing site on outcomes...
  23. ncbi request reprint Stress echocardiography: abnormal response of tissue Doppler-derived indices to dobutamine in the absence of obstructive coronary artery disease in patients with chronic renal failure
    Davinder S Jassal
    Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Echocardiography 24:580-6. 2007
    ..However, the ability of these indices to detect or exclude CAD in patients with chronic renal failure (CRF) is unclear...
  24. ncbi request reprint The impact of endurance exercise training on left ventricular systolic mechanics
    Aaron L Baggish
    Division of Cardiology, Massachusetts General Hospital, Yawkey Suite 5B, 55 Fruit St, Boston, MA 02114, USA
    Am J Physiol Heart Circ Physiol 295:H1109-H1116. 2008
    ..001). EET leads to significant changes in LV systolic function with regional heterogeneity that may be secondary to concomitant RV adaptation. These changes are not detected by conventional measurements such as ejection fraction...
  25. doi request reprint Performance of the 2010 European Society of Cardiology criteria for ECG interpretation in athletes
    Rory B Weiner
    Division of Cardiology, Massachusetts General Hospital, Boston, MA 02114, USA
    Heart 97:1573-7. 2011
    ..The European Society of Cardiology (ESC) recently published revised criteria for ECG interpretation in the athlete...
  26. ncbi request reprint Cardiomyocyte-restricted restoration of nitric oxide synthase 3 attenuates left ventricular remodeling after chronic pressure overload
    Emmanuel S Buys
    Cardiac Ultrasound Laboratory, 55 Fruit Street, Boston, MA 02115 2696, USA
    Am J Physiol Heart Circ Physiol 293:H620-7. 2007
    ..Restoration of NOS3 to the heart of NOS3-deficient mice attenuates LV hypertrophy and dysfunction after TAC, suggesting that NOS3 protects against the adverse LV remodeling induced by prolonged pressure overload...
  27. doi request reprint Blood pressure and left ventricular hypertrophy during American-style football participation
    Rory B Weiner
    Cardiovascular Performance Program, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    Circulation 128:524-31. 2013
    ..The risk of increased blood pressure (BP) and early adulthood hypertension among the substantially larger population of collegiate ASF athletes is not known...
  28. ncbi request reprint Persistent and reversible cardiac dysfunction among amateur marathon runners
    Tomas G Neilan
    Cardiac Ultrasound Laboratory, Division of Cardiology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, 02114 2696, USA
    Eur Heart J 27:1079-84. 2006
    ..However, these described alterations may be limited by the techniques applied. We sought, using less load-dependent methods, to characterize both the extent and the chronology of the cardiac changes associated with endurance events...
  29. pmc Early repolarization pattern in competitive athletes: clinical correlates and the effects of exercise training
    Peter A Noseworthy
    Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA
    Circ Arrhythm Electrophysiol 4:432-40. 2011
    ..Although ERP is common among athletes, prevalence, ECG lead distribution, clinical characteristics, and effects of physical training remain uncertain. We sought to examine the nonanterior ERP in competitive athletes...
  30. ncbi request reprint Absence of left ventricular apical rocking and atrial-ventricular dyssynchrony predicts non-response to cardiac resynchronization therapy
    Francois Tournoux
    Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Eur Heart J Cardiovasc Imaging 13:86-94. 2012
    ..We aimed to determine the negative predictive value of a composite echocardiographic index evaluating atrial-ventricular dyssynchrony (AV-DYS) and intraventricular dyssynchrony...
  31. ncbi request reprint Impact of family hypertension history on exercise-induced cardiac remodeling
    Aaron L Baggish
    Division of Cardiology, Massachusetts General Hospital, Boston, MA, USA
    Am J Cardiol 104:101-6. 2009
    ..In conclusion, these findings suggest that patterns of exercise-induced LV remodeling are strongly associated with FH history status...
  32. ncbi request reprint Sustained improvement in left ventricular diastolic function after alcohol septal ablation for hypertrophic obstructive cardiomyopathy
    Davinder S Jassal
    Cardiac Ultrasound Laboratory, Cardiology Division, Massachusetts General Hospital, Boston, MA 02114, USA
    Eur Heart J 27:1805-10. 2006
    ..Little is known about the longer term impact of ASA on diastolic function...
  33. ncbi request reprint Left ventricular lead proximity to an akinetic segment and impact on outcome of cardiac resynchronization therapy
    Daniel Arzola-Castaner
    Cardiac Arrhythmia Service, Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Cardiovasc Electrophysiol 17:623-7. 2006
    ..However, little is known regarding whether pacing over an akinetic site impacts the contractile response and long-term outcome from CRT...
  34. ncbi request reprint Influence of sex on ventricular remodeling after myocardial infarction in mice
    Justina C Wu
    Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Boston, MA 02114, USA
    J Am Soc Echocardiogr 16:1158-62. 2003
    ..These sex differences should be taken into account when studying murine cardiac adaptation to MI...
  35. ncbi request reprint Changes in mitral regurgitation after replacement of the stenotic aortic valve
    Emily C Waisbren
    Division of Cardiac Surgery, Department of Anesthesia and Critical Care, Massachusetts General Hospital Heart Center, Boston, MA 02114, USA
    Ann Thorac Surg 86:56-62. 2008
    ..This study was undertaken to characterize the magnitude of MR in these patients and identify factors associated with significant postoperative change...
  36. pmc Mechanism of decrease in mitral regurgitation after cardiac resynchronization therapy: optimization of the force-balance relationship
    Jorge Solis
    Division of Cardiology, Massachusetts General Hospital, Boston, MA 02114, USA
    Circ Cardiovasc Imaging 2:444-50. 2009
    ..We hypothesized that CRT improves the comprehensive force balance acting on the valve, including favorable changes in both geometry and LV contractile function...
  37. pmc Brown adipose tissue blood flow and mass in obesity: a contrast ultrasound study in mice
    Maeva Clerte
    Cardiac Ultrasound Laboratory, Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
    J Am Soc Echocardiogr 26:1465-73. 2013
    ..The objective of this study was to evaluate whether contrast ultrasound could characterize BAT mass in two mouse models of obesity: wild-type mice fed a high-fat diet and mutant db/db mice...
  38. pmc In vivo noninvasive characterization of brown adipose tissue blood flow by contrast ultrasound in mice
    David M Baron
    Anesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Circ Cardiovasc Imaging 5:652-9. 2012
    ..After validation, CU was used to study the role of uncoupling protein 1 and nitric oxide synthases in the acute regulation of BAT blood flow...
  39. ncbi request reprint Interlead distance and left ventricular lead electrical delay predict reverse remodeling during cardiac resynchronization therapy
    Faisal M Merchant
    Cardiology Division, Massachusetts General Hospital Heart Center, Harvard Medical School, Boston, Massachusetts 02114, USA
    Pacing Clin Electrophysiol 33:575-82. 2010
    ..However, the relationship between interlead distance and electrical delay in predicting CRT outcomes has not been defined...
  40. ncbi request reprint Echocardiographic measures of acute haemodynamic response after cardiac resynchronization therapy predict long-term clinical outcome
    Francois B Tournoux
    Cardiac Arrhythmia Service and Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Eur Heart J 28:1143-8. 2007
    ....
  41. doi request reprint Cardiovascular screening in college athletes with and without electrocardiography: A cross-sectional study
    Aaron L Baggish
    Massachusetts General Hospital, Boston, 02114, USA
    Ann Intern Med 152:269-75. 2010
    ..To date, no prospective data that compare screening with and without ECG have been available...
  42. doi request reprint Usefulness of low-dose dobutamine echocardiography to predict response and outcome in patients undergoing cardiac resynchronization therapy
    Robert K Altman
    Cardiac Arrhythmia Service, Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Am J Cardiol 108:252-7. 2011
    ..The response rates and heart failure hospitalization-free survival were improved in those patients with a CR >20% and an LV lead tip concordant with the most delayed mechanical segment...
  43. ncbi request reprint Tissue Doppler imaging predicts left ventricular dysfunction and mortality in a murine model of cardiac injury
    Tomas G Neilan
    Cardiac Ultrasound Laboratory, Cardiology Division of the Department of Medicine, Harvard Medical School, USA
    Eur Heart J 27:1868-75. 2006
    ..Tissue Doppler imaging (TDI) can detect subtle LV dysfunction. The aim of this study was to investigate whether TDI indices can predict LV systolic dysfunction and mortality following exposure to doxorubicin (DOX) in mice...
  44. ncbi request reprint Nitric oxide synthase 2 and pressure-overload-induced left ventricular remodelling in mice
    Ryuji Hataishi
    Department of Anaesthesia and Critical Care, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Exp Physiol 91:633-9. 2006
    ..A load-independent index of contractility, Emax, was similar in both strains 42 days after TAC. In conclusion, NOS2 does not appear to have a critical role in the development of LV hypertrophy after chronic pressure overload...
  45. ncbi request reprint In vivo characterization of murine myocardial perfusion with myocardial contrast echocardiography: validation and application in nitric oxide synthase 3 deficient mice
    Michael J Raher
    Cardiac Ultrasound Laboratory, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    Circulation 116:1250-7. 2007
    ..Wild-type (WT) and nitric oxide synthase 3 (NOS3)-deficient (NOS3-/-) mice were studied...
  46. pmc Characteristics of responders to cardiac resynchronization therapy: the impact of echocardiographic left ventricular volume
    Mi Young Park
    Heart Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Clin Cardiol 35:777-80. 2012
    ..One-third of patients who receive cardiac resynchronization therapy (CRT) are classified as nonresponders. Characteristics of responders to CRT have been studied in multiple clinical trials...
  47. ncbi request reprint Frequency and mechanism of persistent systolic anterior motion and mitral regurgitation after septal ablation in obstructive hypertrophic cardiomyopathy
    Francesca N Delling
    Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 100:1691-5. 2007
    ..0001). In conclusion, SAM and MR were often not eliminated using VSA. Mitral valve malposition was a strong predictor of SAM and MR reduction after VSA and may need to be considered in optimizing results of this procedure...
  48. ncbi request reprint Training-specific changes in cardiac structure and function: a prospective and longitudinal assessment of competitive athletes
    Aaron L Baggish
    Div of Cardiology, Dept of Medicine, Massachusetts General Hospital, Yawkey 5, 55 Fruit St, Boston, MA 02114, USA
    J Appl Physiol (1985) 104:1121-8. 2008
    ..EA develop biventricular dilation with enhanced diastolic function, while SA develop isolated, concentric left ventricular hypertrophy with diminished diastolic relaxation...
  49. ncbi request reprint Differences in cardiac parameters among elite rowers and subelite rowers
    Aaron L Baggish
    Division of Cardiology, Massachusetts General Hospital, Boston, MA 02114, USA
    Med Sci Sports Exerc 42:1215-20. 2010
    ..Factors associated with this variability remain incompletely understood. To date, the relationship between the competition level at which athletes participate and their underlying cardiac parameters has not been explored...
  50. ncbi request reprint Myocardial injury and ventricular dysfunction related to training levels among nonelite participants in the Boston marathon
    Tomas G Neilan
    Cardiac Ultrasound Laboratory, Division of Cardiology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02115 2696, USA
    Circulation 114:2325-33. 2006
    ....
  51. ncbi request reprint Relationship of systolic dysfunction to area at risk and infarction size after ischemia-reperfusion in mice
    Ana Clara Tude Rodrigues
    Cardiac Ultrasounds Laboratory, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
    J Am Soc Echocardiogr 17:948-53. 2004
    ..Echocardiography can reliably assess AAR after ischemia-reperfusion in mice; however, it does not allow for precise quantification of the small areas of necrosis that often occur in this setting...
  52. pmc Validation of noninvasive measurements of cardiac output in mice using echocardiography
    Francois Tournoux
    Ultrasound Cardiac Laboratory, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Am Soc Echocardiogr 24:465-70. 2011
    ..Although multiple echocardiographic methods exist to calculate cardiac output (CO), they have not been validated in mice using a reference method...
  53. pmc The impact of isometric handgrip testing on left ventricular twist mechanics
    Rory B Weiner
    Cardiovascular Performance Program, Massachusetts General Hospital, Yawkey Suite 5B, 55 Fruit Street, Boston, MA 02114, USA
    J Physiol 590:5141-50. 2012
    ..71). Peak systolic apical rotation and LVT decrease during IHGT in healthy humans. This impairment of LV twist mechanics may in part underlie the LV dysfunction that can occur in the clinical context of acute increase in afterload...
  54. ncbi request reprint Time course of pressure gradient response after first alcohol septal ablation for obstructive hypertrophic cardiomyopathy
    Danita M Yoerger
    Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 97:1511-4. 2006
    ..In conclusion, many patients who undergo ultimately successful ASA demonstrate triphasic LVOT gradient response patterns, with a large gradient 3 days after the procedure...
  55. ncbi request reprint Outcome and improvement predictors of mitral regurgitation after transcatheter aortic valve implantation
    Ronen Durst
    Cardiac Ultrasound Laboratory and Division of Cardiology, Massachusetts General Hospital, Boston, MA 02114, USA
    J Heart Valve Dis 20:272-81. 2011
    ..The study aim was to define the outcome of MR after transcatheter aortic valve implantation (TAVI) in the TRanscatheter EndoVascular Implantation of VALves (REVIVAL) II trial...
  56. doi request reprint The impact of endurance exercise training on left ventricular torsion
    Rory B Weiner
    Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    JACC Cardiovasc Imaging 3:1001-9. 2010
    ..We sought to examine the effect of endurance exercise training (EET) on peak systolic left ventricular torsion (LVT) and peak early diastolic untwisting rate (UTR)...
  57. ncbi request reprint Estimation of radial strain and rotation using a new algorithm based on speckle tracking
    Francois Tournoux
    Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Soc Echocardiogr 21:1168-74. 2008
    ..Similarly, tracking an ROI relative to a fixed point should provide an estimate of ROT...
  58. ncbi request reprint Myocardial adaptation to short-term high-intensity exercise in highly trained athletes
    Tomas G Neilan
    Cardiac Ultrasound Laboratory, Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02115 2696, USA
    J Am Soc Echocardiogr 19:1280-5. 2006
    ..In conclusion, maximal intensity short-duration exercise was associated with attenuation of LV diastolic function, augmentation of LV systolic function, and a reduction in apical right ventricular contractility...
  59. ncbi request reprint Usefulness of three-dimensionally guided assessment of mitral stenosis using matrix-array ultrasound
    Igal A Sebag
    Cardiac Ultrasound Laboratory, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 96:1151-6. 2005
    ..6% to 6.1% (SEE 0.15 to 0.09 cm(2), p <0.02). In conclusion, matrix-array technology provides a feasible and highly reproducible direct 3-D-guided method for measuring the limiting mitral orifice area...
  60. doi request reprint Aortic sclerosis is associated with mortality and major morbidity in patients undergoing coronary artery bypass surgery
    Aidan W Flynn
    Cardiac Ultrasound Laboratory, Division of Cardiology, Massachusetts General Hospital, Harvard University, 55 Fruit Street, Boston, MA 02114, USA
    Heart 99:247-52. 2013
    ..In this study, we aim to investigate the association between aortic sclerosis and mortality and major morbidity in patients with established coronary artery disease undergoing coronary artery bypass grafting (CABG)...
  61. doi request reprint Incremental value of the preoperative echocardiogram to predict mortality and major morbidity in coronary artery bypass surgery
    Jonathan Afilalo
    Cardiac Ultrasound Laboratory, Division of Cardiology, Massachusetts General Hospital, Harvard University, Boston, MA 02114, USA
    Circulation 127:356-64. 2013
    ..Although echocardiography is commonly performed before coronary artery bypass surgery, there has yet to be a study examining the incremental prognostic value of a complete echocardiogram...
  62. ncbi request reprint Multimodality imaging of pericardial diseases
    Kibar Yared
    Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    JACC Cardiovasc Imaging 3:650-60. 2010
    ..This report reviews the imaging modalities most useful in the assessment of patients with pericardial disease, with an emphasis on the complementary value of multimodality cardiac imaging...
  63. ncbi request reprint Quantitative assessment of regional myocardial function in mice by tissue Doppler imaging: comparison with hemodynamics and sonomicrometry
    Igal A Sebag
    Cardiac Ultrasound Laboratory in the Cardiology Division of the Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Mas 02114, USA
    Circulation 111:2611-6. 2005
    ..The objective of this study was to assess whether myocardial velocities and strain rate (SR) could be obtained by TDI in mice and whether these indices accurately quantified alterations in left ventricular (LV) systolic function...
  64. doi request reprint Use of tissue Doppler to distinguish discrete upper ventricular septal hypertrophy from obstructive hypertrophic cardiomyopathy
    Annabel Chen-Tournoux
    Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 101:1498-503. 2008
    ..Simple echocardiographic indexes may be helpful in distinguishing between patients with DUSH and those with obstructive HC...
  65. doi request reprint Pulmonary artery acceleration time provides an accurate estimate of systolic pulmonary arterial pressure during transthoracic echocardiography
    Kibar Yared
    Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    J Am Soc Echocardiogr 24:687-92. 2011
    ..To date, in the absence of TR, no noninvasive method of deriving EPSPAP has been developed...
  66. ncbi request reprint Inhaled nitric oxide decreases infarction size and improves left ventricular function in a murine model of myocardial ischemia-reperfusion injury
    Ryuji Hataishi
    Department of Anesthesia and Critical Care, Massachusetts General Hospital and Havard Medical School, Boston, MA 02114, USA
    Am J Physiol Heart Circ Physiol 291:H379-84. 2006
    ..Breathing 40 or 80 ppm NO markedly and significantly decreased MI size and improved LV function after ischemia and reperfusion in mice. NO inhalation may represent a novel method to salvage myocardium at risk of I/R injury...
  67. ncbi request reprint Can a teaching intervention reduce interobserver variability in LVEF assessment: a quality control exercise in the echocardiography lab
    Amer M Johri
    Massachusetts General Hospital, Cardiac Ultrasound Laboratory, Cardiology Division, Harvard Medical School, Boston, Massachusetts 02114, USA
    JACC Cardiovasc Imaging 4:821-9. 2011
    ....
  68. ncbi request reprint Surgical management of infective endocarditis: early predictors of short-term morbidity and mortality
    Davinder S Jassal
    Cardiac Ultrasound Laboratory, Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ann Thorac Surg 82:524-9. 2006
    ..Infective endocarditis is a diagnostic and therapeutic challenge that ultimately requires surgical intervention in 20% of all cases. Early determinants of morbidity and mortality in this high risk population are not well described...
  69. ncbi request reprint Pseudodyskinesis of the inferior left ventricular wall: recognizing an echocardiographic mimic of myocardial infarction
    Chaim Yosefy
    Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Am Soc Echocardiogr 20:1374-9. 2007
    ..Such diastolic flattening of the IW is followed by systolic rounding and outward bulging, consistent with extrinsic diastolic compression that is overcome by systolic contraction...
  70. ncbi request reprint Illusion of contraction from out-of-plane translation: can Doppler tissue velocities resolve it?
    David A Playford
    Cardiac Ultrasound Laboratory, Cardiology Division and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    J Am Soc Echocardiogr 16:832-40. 2003
    ....
  71. ncbi request reprint Serum levels of the interleukin-1 receptor family member ST2, cardiac structure and function, and long-term mortality in patients with acute dyspnea
    Ravi V Shah
    Department of Medicine, Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Circ Heart Fail 2:311-9. 2009
    ....
  72. ncbi request reprint Integration of three-dimensional coronary venous angiography with three-dimensional echocardiography for biventricular device implantation
    Moussa Mansour
    Cardiac Arrhythmia Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Heart Rhythm 3:1391-2. 2006
  73. ncbi request reprint Elevated estimated pulmonary artery systolic pressure is associated with an adverse clinical outcome in patients receiving cardiac resynchronization therapy
    Joshua Stern
    Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Pacing Clin Electrophysiol 30:603-7. 2007
    ..We sought to investigate the impact of elevated estimated pulmonary artery systolic pressure (ePASP) on clinical outcome and LV-RR after CRT...
  74. ncbi request reprint Measurement of radial artery contrast intensity to assess cardiac microbubble behavior
    David E Sosnovik
    Cardiac Ultrasound Laboratory, Massachusetts Genral Hospital, Harvard Medical School, Boston, 02114, USA
    J Am Soc Echocardiogr 16:1267-73. 2003
    ..We sought to determine whether analysis of the contrast signal from the radial artery is better able to reflect changes in left ventricular (LV) microbubble dynamics than the signal from the LV itself...
  75. ncbi request reprint Echocardiography improves detection of rejection after heterotopic mouse cardiac transplantation
    Marielle Scherrer-Crosbie
    Cardiology Division, Department of Medicine, Massachusetts General Hospital, 02114, USA
    J Am Soc Echocardiogr 15:1315-20. 2002
    ..Current assessments of cardiac rejection in murine transplant models rely on subjective estimates of the force of the palpable heart beat that have limited sensitivity and precision...
  76. ncbi request reprint A randomized, double-blind, placebo-controlled study of the safety and efficacy of intravenous MCC-135 as an adjunct to primary percutaneous coronary intervention in patients with acute myocardial infarction: rationale and design of the evaluation of MCC-
    Ik Kyung Jang
    Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    J Thromb Thrombolysis 20:147-53. 2005
    ..The rationale, design, and methods of the EVOLVE study, along with two sub-studies, are described in this paper...
  77. ncbi request reprint Images in cardiovascular medicine. Covered stent septal ablation for hypertrophic obstructive cardiomyopathy: initial success but ultimate failure resulting from collateral formation
    Michael A Fifer
    Department of Medicine Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114 3117, USA
    Circulation 107:3248-9. 2003
  78. doi request reprint The impact of moderate-altitude staging on pulmonary arterial hemodynamics after ascent to high altitude
    Aaron L Baggish
    Massachusetts General Hospital, Boston, 02114, USA
    High Alt Med Biol 11:139-45. 2010
    ..SA significantly attenuated the PAP increase associated with continuous direct ascent to high altitude and appeared to uncouple PAP from both alveolar hypoxia and arterial hypoxemia...
  79. ncbi request reprint Unusual position of a prosthetic mitral valve
    Lanqi Hua
    Massachusetts General Hospital, Boston, MA 02114, USA
    J Am Soc Echocardiogr 22:1309.e7-9. 2009
    ..We report the echocardiographictechniques used to evaluate the case of a woman with an unusually positioned prosthetic mitralvalve...
  80. ncbi request reprint Echocardiographic findings in patients meeting task force criteria for arrhythmogenic right ventricular dysplasia: new insights from the multidisciplinary study of right ventricular dysplasia
    Danita M Yoerger
    Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Am Coll Cardiol 45:860-5. 2005
    ..The purpose of this study was to quantify the echocardiographic abnormalities in probands who were newly diagnosed with arrhythmogenic right ventricular dysplasia (ARVD)...
  81. pmc Rapid fatty acid ethyl ester synthesis by porcine myocardium upon ethanol infusion into the left anterior descending coronary artery
    Danita M Yoerger
    Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Pathol 168:1435-42. 2006
    ..These data demonstrate that FAEEs may be mediators of ethanol-induced cardiotoxicity...
  82. doi request reprint Use and appropriateness of transthoracic echocardiography in an academic medical center: a pilot observational study
    Nicole M Martin
    Cardiology Division and the Department of Medicine of the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    J Am Soc Echocardiogr 22:48-52. 2009
    ..Few studies have examined the use of echocardiography in relation to recently released appropriateness criteria for echocardiography...
  83. ncbi request reprint Usefulness of left atrial emptying fraction to predict exercise capacity in patients with normal systolic left ventricular function and without myocardial ischemia
    Mordehay Vaturi
    Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Boston 02114, USA
    Am J Cardiol 95:1014-7. 2005
    ..The left atrial emptying fraction, along with body mass index, was found to be an independent predictor of poor exercise capacity (<5 METs)...
  84. pmc Utility of echocardiography in the evaluation of individuals with cardiomyopathy
    Malissa J Wood
    Cardiac Ultrasound Laboratory, Cardiology Division and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Heart 90:707-12. 2004
  85. ncbi request reprint Integrating functional and anatomical information to facilitate cardiac resynchronization therapy
    Francois B Tournoux
    Cardiology Division, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Pacing Clin Electrophysiol 30:1021-2. 2007
    ..In the case displayed, prior to implantation, the lateral wall was delayed compared to the septum. The LV lead was positioned into the vein over the most delayed region, resulting in improved LV synchrony...
  86. ncbi request reprint A selective inducible NOS dimerization inhibitor prevents systemic, cardiac, and pulmonary hemodynamic dysfunction in endotoxemic mice
    Fumito Ichinose
    Department of Anesthesia and Critical Care and Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114 2620, USA
    Am J Physiol Heart Circ Physiol 285:H2524-30. 2003
    ..Selective inhibition of NOS2 dimerization with BBS-2, while sparing the activities of other NOS isoforms, may prove to be a useful treatment strategy in sepsis...
  87. ncbi request reprint Acute predictors of subacute complete heart block after alcohol septal ablation for obstructive hypertrophic cardiomyopathy
    Annabel A Chen
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 97:264-9. 2006
    ..Patients without acute CHB during ASA or new IVCDs after ASA are at low risk for subacute CHB...
  88. ncbi request reprint Radiographic left ventricular-right ventricular interlead distance predicts the acute hemodynamic response to cardiac resynchronization therapy
    E Kevin Heist
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 96:685-90. 2005
    ..002). Other LV-RV measures on the posteroanterior and lateral radiographs did not correlate with the DeltadP/dt. Use of these findings may help to guide the sites of LV and RV lead placement to maximize the benefit derived from CRT...
  89. ncbi request reprint Long-term survival after surgical revascularization for moderate ischemic mitral regurgitation
    Daniel R Wong
    Division of Cardiac Surgery, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Ann Thorac Surg 80:570-7. 2005
    ..We sought to characterize patient survival and degree of late mitral regurgitation (MR) in patients undergoing surgical revascularization with moderate ischemic MR...
  90. doi request reprint Three-dimensional echocardiography-guided repair of severe paravalvular regurgitation in a bioprosthetic and mechanical mitral valve
    Amer M Johri
    Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Harvard University, 55 Fruit Street, Boston, MA, USA
    Eur J Echocardiogr 10:572-5. 2009
    ..The second case further demonstrates the novel use of full volume colour to define the extent of the regurgitant jet and provides information critical to device sizing and placement...
  91. pmc Association between troponin T and impaired left ventricular relaxation in patients with acute decompensated heart failure with preserved systolic function
    Ravi V Shah
    Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Eur J Echocardiogr 10:765-8. 2009
    ..To examine relationships between cardiac troponin T (cTnT) and parameters of left ventricular (LV) structure and function in patients with acute destabilized heart failure (HF) with preserved LV ejection fraction...
  92. ncbi request reprint Effect of destructive pulse duration on the detection of myocardial perfusion in myocardial contrast echocardiography: In vitro and in vivo observations
    Edda B Bahlmann
    Cardiac Ultrasound Laboratory at the Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    J Am Soc Echocardiogr 15:1440-7. 2002
    ....
  93. ncbi request reprint Echocardiographic assessment of global ventricular function using the myocardial performance index in rats with hypertrophy
    Vera M C Salemi
    Cardiomyopathy Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Artif Organs 28:332-7. 2004
    ..MPI reflects ventricular performance in small animals with LV hypertrophy, showing alterations early after aorta constriction...
  94. ncbi request reprint Heart of darkness: the downside of trastuzumab
    Daniel F Hayes
    J Clin Oncol 24:4056-8. 2006
  95. pmc Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse
    Anne Braun
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Proc Natl Acad Sci U S A 100:7283-8. 2003
    ....
  96. ncbi request reprint Multicenter evaluation of SonoVue for improved endocardial border delineation
    Navin C Nanda
    University of Alabama at Birmingham, Heart Station SW S102, 619 South 19th Street, Birmingham, AL 35249
    Echocardiography 19:27-36. 2002
    ....
  97. ncbi request reprint Noninvasive assessment of hemodynamic parameters in experimental stenosis of the ascending aorta
    Mara D Pires
    Bioengineering Division, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Artif Organs 27:695-700. 2003
    ..Diastolic dysfunction was observed, with an increased early to late ratio of mitral velocities and increased left atrium dimension, consistent with a left ventricular restrictive filling pattern...
  98. ncbi request reprint Recommendations for chamber quantification
    Roberto M Lang
    Med Klinik 2, Erlangen University, Ulmenweg 18, 91054 Erlangen, Germany
    Eur J Echocardiogr 7:79-108. 2006
    ..This document reviews the technical aspects on how to perform quantitative chamber measurements of morphology and function, which is a component of every complete echocardiographic examination...
  99. ncbi request reprint Echocardiographic and angiographic correlations in patients with cardiogenic shock secondary to acute myocardial infarction
    M Joshua Berkowitz
    Cardiovascular Clinical Research Center, New York University School of Medicine, New York, New York, USA
    Am J Cardiol 98:1004-8. 2006
    ..Echocardiography and angiography are valuable and result in similar estimated ejection fractions in a large cohort, but there is wide variation between the techniques in patients...
  100. ncbi request reprint Left ventricular function after exercise training in young men
    Ana Clara Tude Rodrigues
    Heart Institute InCor, HC, FMUSP, Sao Paulo, Brazil
    Am J Cardiol 97:1089-92. 2006
    ..LV function estimated by tissue Doppler is improved despite the lack of changes in standard echocardiographic indexes...
  101. ncbi request reprint Comparison of dobutamine stress echocardiography with and without real-time perfusion imaging for detection of coronary artery disease
    Feng Xie
    University of Nebraska Medical Center, Omaha, Nebraska, USA
    Am J Cardiol 96:506-11. 2005
    ..The addition of real-time perfusion imaging after intravenous contrast during dobutamine stress echocardiography has the potential to improve detection of coronary artery disease...