Andrew J K Phillips

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Mammalian rest/activity patterns explained by physiologically based modeling
    A J K Phillips
    Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Comput Biol 9:e1003213. 2013
  2. pmc Arousal state feedback as a potential physiological generator of the ultradian REM/NREM sleep cycle
    A J K Phillips
    Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Ave, Suite 438, Boston, MA 02115, USA
    J Theor Biol 319:75-87. 2013
  3. doi request reprint Probing the mechanisms of chronotype using quantitative modeling
    A J K Phillips
    School of Physics, University of Sydney, New South Wales, Australia
    J Biol Rhythms 25:217-27. 2010
  4. pmc Mammalian sleep dynamics: how diverse features arise from a common physiological framework
    Andrew J K Phillips
    School of Physics, University of Sydney, Sydney, Australia
    PLoS Comput Biol 6:e1000826. 2010
  5. pmc Revisiting spontaneous internal desynchrony using a quantitative model of sleep physiology
    Andrew J K Phillips
    Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Biol Rhythms 26:441-53. 2011
  6. pmc A mathematical model of the circadian phase-shifting effects of exogenous melatonin
    Emily R Breslow
    Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, MA 02115, USA
    J Biol Rhythms 28:79-89. 2013
  7. doi request reprint Exploring sleepiness and entrainment on permanent shift schedules in a physiologically based model
    Svetlana Postnova
    School of Physics, University of Sydney, Sydney, NSW, Australia
    J Biol Rhythms 27:91-102. 2012
  8. doi request reprint A physiologically based model of orexinergic stabilization of sleep and wake
    Ben D Fulcher
    School of Physics, The University of Sydney, Sydney, New South Wales, Australia
    PLoS ONE 9:e91982. 2014
  9. pmc Sex difference in the near-24-hour intrinsic period of the human circadian timing system
    Jeanne F Duffy
    Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 108:15602-8. 2011

Collaborators

Detail Information

Publications9

  1. pmc Mammalian rest/activity patterns explained by physiologically based modeling
    A J K Phillips
    Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Comput Biol 9:e1003213. 2013
    ..Given the ubiquitous effects of temporal organization on all aspects of animal behavior and physiology, this study sheds light on the physiological changes required to orchestrate adaptation to various temporal niches. ..
  2. pmc Arousal state feedback as a potential physiological generator of the ultradian REM/NREM sleep cycle
    A J K Phillips
    Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Ave, Suite 438, Boston, MA 02115, USA
    J Theor Biol 319:75-87. 2013
    ..These findings have important implications in terms of sleep physiology and they provide a parsimonious explanation for the observed ultradian rhythm of REM/NREM sleep...
  3. doi request reprint Probing the mechanisms of chronotype using quantitative modeling
    A J K Phillips
    School of Physics, University of Sydney, New South Wales, Australia
    J Biol Rhythms 25:217-27. 2010
    ..Physiologically based modeling can thus guide diagnosis of sleep pathologies...
  4. pmc Mammalian sleep dynamics: how diverse features arise from a common physiological framework
    Andrew J K Phillips
    School of Physics, University of Sydney, Sydney, Australia
    PLoS Comput Biol 6:e1000826. 2010
    ..These wide-ranging findings suggest that the core physiological mechanisms controlling sleep are common to many mammalian orders, with slight evolutionary modifications accounting for interspecies differences...
  5. pmc Revisiting spontaneous internal desynchrony using a quantitative model of sleep physiology
    Andrew J K Phillips
    Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Biol Rhythms 26:441-53. 2011
    ..Our findings suggest that feedback from behavioral choices to physiology could play an important role in spontaneous internal desynchrony...
  6. pmc A mathematical model of the circadian phase-shifting effects of exogenous melatonin
    Emily R Breslow
    Division of Sleep Medicine, Brigham and Women s Hospital, Harvard Medical School, MA 02115, USA
    J Biol Rhythms 28:79-89. 2013
    ..This model can simulate experimental protocols using oral melatonin, with potential application to guide dose size and timing to optimally shift and entrain circadian rhythms...
  7. doi request reprint Exploring sleepiness and entrainment on permanent shift schedules in a physiologically based model
    Svetlana Postnova
    School of Physics, University of Sydney, Sydney, NSW, Australia
    J Biol Rhythms 27:91-102. 2012
    ..Overall, the model supports experimental observations, providing new insights into the mechanisms and allowing the examination of conditions that are not accessible experimentally...
  8. doi request reprint A physiologically based model of orexinergic stabilization of sleep and wake
    Ben D Fulcher
    School of Physics, The University of Sydney, Sydney, New South Wales, Australia
    PLoS ONE 9:e91982. 2014
    ....
  9. pmc Sex difference in the near-24-hour intrinsic period of the human circadian timing system
    Jeanne F Duffy
    Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 108:15602-8. 2011
    ..0 h (35% vs. 14%; P < 0.01). The shorter average intrinsic circadian period observed in women may have implications for understanding sex differences in habitual sleep duration and insomnia prevalence...