Research Topics
| Page B PennellSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
| Collaborators
|
Detail Information
Publications
Differential effects of antiepileptic drugs on neonatal outcomesP B Pennell
Harvard Medical School, Brigham and Women s Hospital, 75 Francis Street, Brigham and Women s Hospital, Boston, MA 02115, USA
Epilepsy Behav 24:449-56. 2012..Differential risks among the AEDs can help inform decisions about AED selection for women during childbearing years...
Hormonal aspects of epilepsyPage B Pennell
Division of Epilepsy, Department of Neurology, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
Neurol Clin 27:941-65. 2009..Additionally, development of the neurosteroid analog ganaxolone provides a novel approach that can potentially be used across both genders and all age groups...
Relationship of child IQ to parental IQ and education in children with fetal antiepileptic drug exposureKimford J Meador
Department of Neurology, Emory University, Atlanta, GA 30322, USA
Epilepsy Behav 21:147-52. 2011....
Foetal antiepileptic drug exposure and verbal versus non-verbal abilities at three years of ageKimford J Meador
Department of Neurology, Emory University, Atlanta, GA 30322, USA
Brain 134:396-404. 2011..Additional research is needed to confirm these findings, extend the study to other drugs, define the risks associated with drug treatment for seizures in the neonates, and understand the underlying mechanisms...
Differential effects of antiepileptic drugs on neuroactive steroids in men with epilepsyAndrew G Herzog
Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
Epilepsia 47:1945-8. 2006..To compare serum levels of neuroactive steroids among men with epilepsy who take various antiepileptic drugs, untreated men with epilepsy and normal controls (NC)...
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugsKimford J Meador
Department of Neurology, Emory University, Woodruff Memorial Research Bldg, 101 Woodruff Cir, Suite 6000, Atlanta, GA 30322, USA
N Engl J Med 360:1597-605. 2009....
Gender-specific psychosocial impact of living with epilepsyPage B Pennell
Department of Neurology, Emory University School of Medicine, 101 Woodruff Circle, Suite 6000, Atlanta, GA 30322, USA
Epilepsy Behav 15:S20-5. 2009..These gender-specific factors should be a key consideration when counseling and treating patients with epilepsy...
Variation of seizure frequency with ovulatory status of menstrual cyclesAndrew G Herzog
Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Epilepsia 52:1843-8. 2011..To determine if seizure frequency differs between anovulatory and ovulatory cycles...
Antiepileptic drug use in women of childbearing ageKimford J Meador
Department of Neurology, Emory University, Woodruff Memorial Research Building, 101 Woodruff Circle, Suite 6000, Mail Stop 1930 001 1AN, Atlanta, GA 30322, USA
Epilepsy Behav 15:339-43. 2009..Except for the top two AED monotherapies, there were marked differences in other monotherapies and in polytherapies between U.S. and UK centers. Future investigations are needed to examine reasons for drug choice...
Pharmacology of antiepileptic drugs during pregnancy and lactationPage B Pennell
Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA
Epilepsy Behav 11:263-9. 2007..The report provides an overview of these key topics, highlights gaps in the current knowledge, and provides future directions for needed research...
Efficacy of safety signals in the epilepsy monitoring unit (EMU): should we worry?Hae W Shin
Edward B Bromfield Epilepsy Program, Department of Neurology, Brigham and Women s Hospital, Boston, MA, USA
Epilepsy Behav 23:458-61. 2012..Future studies investigating more effective techniques to capture every epileptic seizure are warranted as 24/7 monitoring by healthcare professionals is not feasible in many settings...
Female reproductive factors and risk of seizure or epilepsy: data from the Nurses' Health Study IIBarbara A Dworetzky
Department of Neurology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Epilepsia 53:e1-4. 2012..76, 95% CI 1.10-2.81) increased the risk of isolated seizure. Oral contraceptive use and parity were not associated with isolated seizure or epilepsy. Therefore, menstrual factors were associated with risk of seizure and epilepsy...
Pregnancy in women who have epilepsyPage B Pennell
Emory Epilepsy Program, Department of Neurology, Emory University School of Medicine, 101 Woodruff Circle, Suite 6000 Atlanta, GA 30322, USA
Neurol Clin 22:799-820. 2004....
Antiepileptic drug pharmacokinetics during pregnancy and lactationPage B Pennell
Department of Neurology, Emory Epilepsy Center, Emory University School of Medicine, Atlanta, GA 30322, USA
Neurology 61:S35-42. 2003....
The importance of monotherapy in pregnancyPage B Pennell
Epilepsy Monitoring Unit, Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA
Neurology 60:S31-8. 2003..Prenatal screening for major malformations should be offered. Careful planning and management of any pregnancy in women with epilepsy is essential to increase the likelihood of a healthy outcome for mother and infant...
Differential effects of antiepileptic drugs on sexual function and reproductive hormones in men with epilepsy: interim analysis of a comparison between lamotrigine and enzyme-inducing antiepileptic drugsAndrew G Herzog
Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
Epilepsia 45:764-8. 2004..We compared sexual function and reproductive hormone levels among men with localization-related epilepsy (LRE) taking various antiepileptic drugs (AEDs) and normal controls (NC)...
Disparities in NIH funding for epilepsy researchKimford J Meador
Department of Neurology, Emory University, Woodruff Memorial Research Building, 101 Woodruff Circle, Suite 6000, Atlanta, GA 30322, USA
Neurology 77:1305-7. 2011..The disparity cannot be explained by differences in the overall impact of these diseases on US citizens. Greater transparency in the review and funding process is needed to disclose the reason for this disparity...
