Research Topics
Species | Nina P PaynterSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Detail Information
Publications
Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3Nina P Paynter
Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Ann Intern Med 150:65-72. 2009..Although genetic variation at chromosome 9p21.3 is associated with incident cardiovascular disease, it is unclear whether screening for this polymorphism improves risk prediction...
A bias-corrected net reclassification improvement for clinical subgroupsNina P Paynter
Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
Med Decis Making 33:154-62. 2013..Comparing prediction models using reclassification within subgroups at intermediate risk is often of clinical interest...
Effect of correcting for long-term variation in major coronary heart disease risk factors: relative hazard estimation and risk prediction in the Atherosclerosis Risk in Communities StudyNina P Paynter
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
Ann Epidemiol 22:191-7. 2012..To examine the effect of correcting coronary heart disease (CHD) risk factors for long-term within-person variation on CHD risk...
Cardiovascular risk prediction in diabetic men and women using hemoglobin A1c vs diabetes as a high-risk equivalentNina P Paynter
Brigham and Women s Hospital, Division of Preventive Medicine, 900 Commonwealth Ave, Boston, MA 02215, USA
Arch Intern Med 171:1712-8. 2011....
Lipoprotein subclass abnormalities and incident hypertension in initially healthy womenNina P Paynter
Divisions of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Clin Chem 57:1178-87. 2011..Whether lipoprotein particle size or subclass concentrations play a role in the development of hypertension is unknown...
Paired comparison of observed and expected coronary heart disease rates over 12 years from the Atherosclerosis Risk in Communities StudyNina P Paynter
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, USA
Ann Epidemiol 20:683-90. 2010..To quantify the relationship between coronary heart disease (CHD) risk factor levels and changes over time and population-wide CHD morbidity and mortality...
Association between a literature-based genetic risk score and cardiovascular events in womenNina P Paynter
Center for Cardiovascular Disease Prevention and the Divisions of Preventive Medicine and Cardiovascular Diseases, Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
JAMA 303:631-7. 2010..While multiple genetic markers associated with cardiovascular disease have been identified by genome-wide association studies, their aggregate effect on risk beyond traditional factors is uncertain, particularly among women...
Prediction of incident hypertension risk in women with currently normal blood pressureNina P Paynter
The Center for Cardiovascular Disease Prevention and the Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Mass 02215, USA
Am J Med 122:464-71. 2009..We examined whether a hypertension risk prediction model based on clinical characteristics and blood biomarkers might improve on risk prediction based on current blood pressure alone...
C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for menPaul M Ridker
Donald W Reynolds Center for Cardiovascular Research, Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
Circulation 118:2243-51, 4p following 2251. 2008....
Clinical utility of lipoprotein-associated phospholipase A₂ for cardiovascular disease prediction in a multiethnic cohort of womenNancy R Cook
Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
Clin Chem 58:1352-63. 2012..Findings regarding the association of lipoprotein-associated phospholipase A₂ (Lp-PLA2) activity and mass with incident cardiovascular disease (CVD) have been inconsistent, and their role in risk prediction is uncertain...
Socioeconomic status and incident type 2 diabetes mellitus: data from the Women's Health StudyTimothy C Lee
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
PLoS ONE 6:e27670. 2011..We prospectively examined whether socioeconomic status (SES) predicts incident type II diabetes (diabetes), a cardiovascular risk equivalent and burgeoning public health epidemic among women...
Performance of reclassification statistics in comparing risk prediction modelsNancy R Cook
Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA, USA
Biom J 53:237-58. 2011..The relative power of the RC statistic, a test of calibration, and the NRI, a test of discrimination, varied depending on the model assumptions. These tools provide unique but complementary information...
Comparison of the Framingham and Reynolds Risk scores for global cardiovascular risk prediction in the multiethnic Women's Health InitiativeNancy R Cook
Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
Circulation 125:1748-56, S1-11. 2012..Framingham-based and Reynolds Risk scores for cardiovascular disease (CVD) prediction have not been directly compared in an independent validation cohort...
Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart studyCaroline S Fox
National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts, USA
Diabetes Care 31:1582-4. 2008..We assessed the lifetime risk of cardiovascular disease (CVD) among individuals with and without obesity and diabetes...
Prognostic factors in pediatric high-grade astrocytoma: the importance of accurate pathologic diagnosisRussell K Hales
Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, 401 North Broadway, Suite 1440, Baltimore, MD 21231, USA
J Neurooncol 99:65-71. 2010..Pathologic misdiagnosis should be suspected in patients who are long term survivors of a pediatric high grade astrocytoma...
A double blind randomized placebo control trial of levetiracetam in Tourette syndromeConstance L Smith Hicks
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Mov Disord 22:1764-70. 2007..There was no significant difference between treatments and no evidence of sequence or cross-over effects. In conclusion, Levetiracetam is not more beneficial than placebo in suppressing tics in children with TS...
The effect of weight loss on C-reactive protein: a systematic reviewElizabeth Selvin
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21287, USA
Arch Intern Med 167:31-9. 2007..Our objective was to test the hypothesis that weight loss is directly related to a decline in CRP level...
Coffee and sweetened beverage consumption and the risk of type 2 diabetes mellitus: the atherosclerosis risk in communities studyNina P Paynter
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Am J Epidemiol 164:1075-84. 2006..In summary, increased coffee consumption was significantly associated with a decreased risk of diagnosed type 2 diabetes mellitus in community-based US adults...
