Nina P Paynter

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3
    Nina P Paynter
    Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Ann Intern Med 150:65-72. 2009
  2. pmc A bias-corrected net reclassification improvement for clinical subgroups
    Nina P Paynter
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
    Med Decis Making 33:154-62. 2013
  3. pmc Effect of correcting for long-term variation in major coronary heart disease risk factors: relative hazard estimation and risk prediction in the Atherosclerosis Risk in Communities Study
    Nina P Paynter
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    Ann Epidemiol 22:191-7. 2012
  4. pmc Association between a literature-based genetic risk score and cardiovascular events in women
    Nina P Paynter
    Center for Cardiovascular Disease Prevention and the Divisions of Preventive Medicine and Cardiovascular Diseases, Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
    JAMA 303:631-7. 2010
  5. pmc Cardiovascular risk prediction in diabetic men and women using hemoglobin A1c vs diabetes as a high-risk equivalent
    Nina P Paynter
    Brigham and Women s Hospital, Division of Preventive Medicine, 900 Commonwealth Ave, Boston, MA 02215, USA
    Arch Intern Med 171:1712-8. 2011
  6. pmc Lipoprotein subclass abnormalities and incident hypertension in initially healthy women
    Nina P Paynter
    Divisions of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Clin Chem 57:1178-87. 2011
  7. pmc Prediction of incident hypertension risk in women with currently normal blood pressure
    Nina P Paynter
    The Center for Cardiovascular Disease Prevention and the Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Mass 02215, USA
    Am J Med 122:464-71. 2009
  8. pmc Paired comparison of observed and expected coronary heart disease rates over 12 years from the Atherosclerosis Risk in Communities Study
    Nina P Paynter
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, USA
    Ann Epidemiol 20:683-90. 2010
  9. pmc C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for men
    Paul M Ridker
    Donald W Reynolds Center for Cardiovascular Research, Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Circulation 118:2243-51, 4p following 2251. 2008
  10. pmc Clinical utility of lipoprotein-associated phospholipase A₂ for cardiovascular disease prediction in a multiethnic cohort of women
    Nancy R Cook
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Clin Chem 58:1352-63. 2012

Detail Information

Publications21

  1. pmc Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3
    Nina P Paynter
    Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Ann Intern Med 150:65-72. 2009
    ..Although genetic variation at chromosome 9p21.3 is associated with incident cardiovascular disease, it is unclear whether screening for this polymorphism improves risk prediction...
  2. pmc A bias-corrected net reclassification improvement for clinical subgroups
    Nina P Paynter
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
    Med Decis Making 33:154-62. 2013
    ..Comparing prediction models using reclassification within subgroups at intermediate risk is often of clinical interest...
  3. pmc Effect of correcting for long-term variation in major coronary heart disease risk factors: relative hazard estimation and risk prediction in the Atherosclerosis Risk in Communities Study
    Nina P Paynter
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    Ann Epidemiol 22:191-7. 2012
    ..To examine the effect of correcting coronary heart disease (CHD) risk factors for long-term within-person variation on CHD risk...
  4. pmc Association between a literature-based genetic risk score and cardiovascular events in women
    Nina P Paynter
    Center for Cardiovascular Disease Prevention and the Divisions of Preventive Medicine and Cardiovascular Diseases, Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
    JAMA 303:631-7. 2010
    ..While multiple genetic markers associated with cardiovascular disease have been identified by genome-wide association studies, their aggregate effect on risk beyond traditional factors is uncertain, particularly among women...
  5. pmc Cardiovascular risk prediction in diabetic men and women using hemoglobin A1c vs diabetes as a high-risk equivalent
    Nina P Paynter
    Brigham and Women s Hospital, Division of Preventive Medicine, 900 Commonwealth Ave, Boston, MA 02215, USA
    Arch Intern Med 171:1712-8. 2011
    ....
  6. pmc Lipoprotein subclass abnormalities and incident hypertension in initially healthy women
    Nina P Paynter
    Divisions of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Clin Chem 57:1178-87. 2011
    ..Whether lipoprotein particle size or subclass concentrations play a role in the development of hypertension is unknown...
  7. pmc Prediction of incident hypertension risk in women with currently normal blood pressure
    Nina P Paynter
    The Center for Cardiovascular Disease Prevention and the Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Mass 02215, USA
    Am J Med 122:464-71. 2009
    ..We examined whether a hypertension risk prediction model based on clinical characteristics and blood biomarkers might improve on risk prediction based on current blood pressure alone...
  8. pmc Paired comparison of observed and expected coronary heart disease rates over 12 years from the Atherosclerosis Risk in Communities Study
    Nina P Paynter
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, USA
    Ann Epidemiol 20:683-90. 2010
    ..To quantify the relationship between coronary heart disease (CHD) risk factor levels and changes over time and population-wide CHD morbidity and mortality...
  9. pmc C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for men
    Paul M Ridker
    Donald W Reynolds Center for Cardiovascular Research, Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Circulation 118:2243-51, 4p following 2251. 2008
    ....
  10. pmc Clinical utility of lipoprotein-associated phospholipase A₂ for cardiovascular disease prediction in a multiethnic cohort of women
    Nancy R Cook
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Clin Chem 58:1352-63. 2012
    ..Findings regarding the association of lipoprotein-associated phospholipase A₂ (Lp-PLA2) activity and mass with incident cardiovascular disease (CVD) have been inconsistent, and their role in risk prediction is uncertain...
  11. pmc Socioeconomic status and incident type 2 diabetes mellitus: data from the Women's Health Study
    Timothy C Lee
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 6:e27670. 2011
    ..We prospectively examined whether socioeconomic status (SES) predicts incident type II diabetes (diabetes), a cardiovascular risk equivalent and burgeoning public health epidemic among women...
  12. pmc Performance of reclassification statistics in comparing risk prediction models
    Nancy R Cook
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Biom J 53:237-58. 2011
    ..The relative power of the RC statistic, a test of calibration, and the NRI, a test of discrimination, varied depending on the model assumptions. These tools provide unique but complementary information...
  13. pmc Cardiovascular disease risk prediction in women: is there a role for novel biomarkers?
    Nina P Paynter
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA
    Clin Chem 60:88-97. 2014
    ..The incidence of CVD is lower in women than men, and the effects of a number of traditional biomarkers on CVD risk differ in women compared to men. Both of these factors influence the ability to accurately predict CVD risk...
  14. pmc Novel locus including FGF21 is associated with dietary macronutrient intake
    Audrey Y Chu
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Hum Mol Genet 22:1895-902. 2013
    ..9 × 10(-9)). A cytokine involved in cellular metabolism, FGF21 is a potential susceptibility gene for obesity and type 2 diabetes. Our results highlight the potential of genetic variation for determining dietary macronutrient intake...
  15. pmc Comparison of the Framingham and Reynolds Risk scores for global cardiovascular risk prediction in the multiethnic Women's Health Initiative
    Nancy R Cook
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA
    Circulation 125:1748-56, S1-11. 2012
    ..Framingham-based and Reynolds Risk scores for cardiovascular disease (CVD) prediction have not been directly compared in an independent validation cohort...
  16. pmc Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study
    Caroline S Fox
    National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts, USA
    Diabetes Care 31:1582-4. 2008
    ..We assessed the lifetime risk of cardiovascular disease (CVD) among individuals with and without obesity and diabetes...
  17. doi request reprint Prognostic factors in pediatric high-grade astrocytoma: the importance of accurate pathologic diagnosis
    Russell K Hales
    Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, 401 North Broadway, Suite 1440, Baltimore, MD 21231, USA
    J Neurooncol 99:65-71. 2010
    ..Pathologic misdiagnosis should be suspected in patients who are long term survivors of a pediatric high grade astrocytoma...
  18. doi request reprint High-density lipoprotein particle subclass heterogeneity and incident coronary heart disease
    Akintunde O Akinkuolie
    Divisions of Preventive Medicine and Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    Circ Cardiovasc Qual Outcomes 7:55-63. 2014
    ..We prospectively evaluated the association of HDL subclasses, defined by a recently proposed nomenclature, with incident coronary heart disease (CHD)...
  19. ncbi request reprint A double blind randomized placebo control trial of levetiracetam in Tourette syndrome
    Constance L Smith-Hicks
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Mov Disord 22:1764-70. 2007
    ..There was no significant difference between treatments and no evidence of sequence or cross-over effects. In conclusion, Levetiracetam is not more beneficial than placebo in suppressing tics in children with TS...
  20. ncbi request reprint The effect of weight loss on C-reactive protein: a systematic review
    Elizabeth Selvin
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21287, USA
    Arch Intern Med 167:31-9. 2007
    ..Our objective was to test the hypothesis that weight loss is directly related to a decline in CRP level...
  21. ncbi request reprint Coffee and sweetened beverage consumption and the risk of type 2 diabetes mellitus: the atherosclerosis risk in communities study
    Nina P Paynter
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Am J Epidemiol 164:1075-84. 2006
    ..In summary, increased coffee consumption was significantly associated with a decreased risk of diagnosed type 2 diabetes mellitus in community-based US adults...