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Genomes and Genes | Esther OlivaSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Publications
Mixed tumors of the vagina: an immunohistochemical study of 13 cases with emphasis on the cell of origin and potential aid in differential diagnosisEsther Oliva
James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, USA
Mod Pathol 17:1243-50. 2004..MTsV are positive for h-Caldesmon and CD10, two markers that have been used in gynecologic pathology primarily to aid in establishing the smooth muscle or endometrial stromal phenotype of a neoplasm...
CD10 expression in the female genital tract: does it have useful diagnostic applications?Esther Oliva
Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Adv Anat Pathol 11:310-5. 2004....
Sertoli cell tumors of the ovary: a clinicopathologic and immunohistochemical study of 54 casesEsther Oliva
James Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Am J Surg Pathol 29:143-56. 2005..The tumors typically occur in young females, sometimes children who typically present with sexual precocity, and occasional patients have Peutz-Jeghers syndrome...
High frequency of JAZF1-JJAZ1 gene fusion in endometrial stromal tumors with smooth muscle differentiation by interphase FISH detectionEsther Oliva
Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
Am J Surg Pathol 31:1277-84. 2007..Our results indicate that the detection of this chromosomal abnormality can be used to diagnose ESTs with smooth muscle differentiation when the smooth muscle component is predominant...
CD10 expression in pure stromal and sex cord-stromal tumors of the ovary: an immunohistochemical analysis of 101 casesEsther Oliva
Pathology Department, Massachusetts General Hospital, Boston, MA 02114, USA
Int J Gynecol Pathol 26:359-67. 2007..CD10 may play a useful role in aiding the differential between endometrial stromal tumors in the ovary and SCST and stromal tumors...
An immunohistochemical analysis of endometrial stromal and smooth muscle tumors of the uterus: a study of 54 cases emphasizing the importance of using a panel because of overlap in immunoreactivity for individual antibodiesEsther Oliva
James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Am J Surg Pathol 26:403-12. 2002..8) CD34, CD99, and keratin have no or minimal role in this area, but keratin positivity in smooth muscle tumors should not lead to their confusion with epithelial tumors...
Clear cell carcinoma of the urinary bladder: a report and comparison of four tumors of mullerian origin and nine of probable urothelial origin with discussion of histogenesis and diagnostic problemsEsther Oliva
James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Fruit Street, Boston, MA 02114, USA
Am J Surg Pathol 26:190-7. 2002....
Clinicopathological and molecular analysis of endometrial carcinoma associated with tamoxifenJulia Turbiner
Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
Mod Pathol 21:925-36. 2008..In conclusion, there was a direct relationship between tamoxifen exposure and overexpression of beta-catenin oncoprotein, which is known to play a major role in the pathogenesis of estrogen-driven, type I endometrial adenocarcinoma...
Uterine tumors resembling ovarian sex cord tumors (UTROSCT) lack the JAZF1-JJAZ1 translocation frequently seen in endometrial stromal tumorsPaul N Staats
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Am J Surg Pathol 33:1206-12. 2009....
Decreased survival in EGFR gene amplified vulvar carcinomaWhitfield B Growdon
Vincent Center for Reproductive Biology, Vincent Obstetrics and Gynecology Service, Massachusetts General Hospital, THR 901A, 55 Fruit Street, Boston, Massachusetts 02114, USA
Gynecol Oncol 111:289-97. 2008....
Frequency of known gene rearrangements in endometrial stromal tumorsSarah Chiang
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
Am J Surg Pathol 35:1364-72. 2011..The presence of identical gene rearrangements in both uterine and extrauterine ESTs suggests a similar pathogenesis. The presence of detectable gene rearrangements in uterine ESS may predict better patient outcome...
Case records of the Massachusetts General Hospital. Case 11-2006. A 54-year-old woman with a mass in the pelvisCarolyn N Krasner
Gillette Center for Women's Cancers, Massachusetts General Hospital, USA
N Engl J Med 354:1615-25. 2006
The Li-Fraumeni syndrome (LFS): a model for the initiation of p53 signatures in the distal Fallopian tubeWa Xian
Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
J Pathol 220:17-23. 2010..This is in keeping with a general model of carcinogenesis, in which different and often independent risk factors operate at multiple points in the serous carcinogenic spectrum...
Uterine tumors resembling ovarian sex cord tumors: an ultrastructural analysis of 13 casesMamta Gupta
Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
Ultrastruct Pathol 34:16-24. 2010....
Functional analyses of the cancer stem cell-like properties of human endometrial tumor initiating cellsAnne M Friel
Vincent Center for Reproductive Biology, Vincent Obstetrics and Gynecology Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Cell Cycle 7:242-9. 2008..Additionally, we identified SP fractions in primary EnCa. Together these results are consistent with the hypothesis that EnCa contain a subpopulation of tumor initiating cells with stem like properties...
Mechanisms of Cables 1 gene inactivation in human ovarian cancer developmentHideo Sakamoto
Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachussetts 02114, USA
Cancer Biol Ther 7:180-88. 2008..Together these findings suggest that multiple mechanisms underlie the loss of Cables 1 expression in ovarian cancer cells, supporting the hypothesis that Cables 1 is a tumor suppressor in human ovarian cancer...
Mullerian adenosarcomas: an immunophenotypic analysis of 35 casesRobert A Soslow
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Am J Surg Pathol 32:1013-21. 2008..ER, PR, and CD10 expression was lost in MA-SOs relative to conventional low-grade stromal areas of mullerian/mesodermal adenosarcomas, reflecting the "dedifferentiation" of this component...
Defining the extent of cables loss in endometrial cancer subtypes and its effectiveness as an inhibitor of cell proliferation in malignant endometrial cells in vitro and in vivoRobert L DeBernardo
Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Cancer Biol Ther 4:103-7. 2005..Collectively these results suggest that Cables is an important regulator of cell proliferation and loss of Cables expression contributes to the development of all types of EC...
Pathogenetic pathways in ovarian endometrioid adenocarcinoma: a molecular study of 29 casesJulia Turbiner Geyer
Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
Am J Surg Pathol 33:1157-63. 2009..On the basis of these results, we suggest that there may also be a dual pathogenetic pathway for EOC...
Clinicopathologic analysis of 187 high-grade endometrial carcinomas of different histologic subtypes: similar outcomes belie distinctive biologic differencesRobert A Soslow
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Am J Surg Pathol 31:979-87. 2007....
Cytogenetic and molecular aberrations in endometrial stromal tumorsSarah Chiang
Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
Hum Pathol 42:609-17. 2011..In this review, we summarize the recent advances in the molecular pathology of endometrial stromal tumors...
Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: a study in serial samplesRichard T Penson
Division of Hematology/Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
Gynecol Oncol 93:98-106. 2004..However, P-gp over-expression is a significant prognostic factor, and at the time of disease, relapse is inversely correlated with tumor response to paclitaxel...
A role for BRCA1 in uterine leiomyosarcomaDeyin Xing
Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USA
Cancer Res 69:8231-5. 2009..These data indicate that the loss of BRCA1 function may be an important step in the progression of ULMS. Our findings provide a rationale for investigating therapies that target BRCA1 deficiency in ULMS...
Morphologic spectrum of immunohistochemically characterized clear cell carcinoma of the ovary: a study of 155 casesDeborah DeLair
Department of Pathology, Memorial Sloan Kettering Cancer Center, Vancouver General Hospital, NY, USA
Am J Surg Pathol 35:36-44. 2011..Clear cell-rich tumors with features that depart from the classical morphologic appearances described herein should suggest the possibility of an alternative diagnosis...
Endometrial stromal nodules and endometrial stromal tumors with limited infiltration: a clinicopathologic study of 50 casesAdriana Dionigi
James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Am J Surg Pathol 26:567-81. 2002....
Uterine malignant mixed mullerian tumors should not be included in studies of endometrial carcinomaAmi P Vaidya
Division of Gynecologic Oncology, Gillette Center for Women's Cancers, Massachusetts General Hospital, Boston, MA 02114, USA
Gynecol Oncol 103:684-7. 2006..Given the discrepancy in survival, these patients should not be included in studies of endometrial carcinoma. Further investigations are necessary to identify factors to improve survival of these patients...
The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumorCheng Han Lee
Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
Am J Surg Pathol 36:641-53. 2012..Thus, their distinction from typical JAZF1 ESS is important for prognostic and therapeutic purposes...
Liposarcoma arising in uterine lipoleiomyoma: a report of 3 cases and review of the literatureAnna Greene McDonald
Department of Pathology, Massachusetts General Hospital, Boston, 02114, USA
Am J Surg Pathol 35:221-7. 2011..Most uterine sarcomas arise de novo, with malignant transformation of a benign mesenchymal tumor being a very rare event, and is reported only in leiomyomata...
Histopathologic prognostic factors in stage I leiomyosarcoma of the uterus: a detailed analysis of 27 casesWei Lien Wang
Massachusetts General Hospital, Boston, MA, USA
Am J Surg Pathol 35:522-9. 2011....
Solid pseudopapillary neoplasm of the ovary: a report of 3 primary ovarian tumors resembling those of the pancreasVikram Deshpande
Massachusetts General Hospital, Harvard Medical School, Boston, USA
Am J Surg Pathol 34:1514-20. 2010..The morphologic and immunohistochemical similarity to pancreatic solid pseudopapillary neoplasm facilitates the accurate diagnosis of this rare ovarian neoplasm...
Smooth muscle tumors of the ovary: a clinicopathologic study of 54 cases emphasizing prognostic criteria, histologic variants, and differential diagnosisMelinda F Lerwill
James Homer Wright Pathology Laboratories of the Massachusetts General Hospital and the Department of Pathology, Harvard Medical School, Boston, MA 021114, USA
Am J Surg Pathol 28:1436-51. 2004..The main tumors in the differential diagnosis are those in the fibroma/thecoma category, spindle cell carcinomas, and metastatic gastrointestinal stromal tumors...
Molecular profile of grade 3 endometrioid endometrial carcinoma: is it a type I or type II endometrial carcinoma?Teresa Alvarez
The James Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, USA
Am J Surg Pathol 36:753-61. 2012....
Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying termJulia Turbiner
Pathology Department, Massachusetts General Hospital, Boston, MA 02114, USA
Am J Surg Pathol 31:489-500. 2007....
beta tubulin mutations are rare in human ovarian carcinomaDiana E Lamendola
Department of Hematology/Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
Anticancer Res 23:681-6. 2003..CONCLUSION: This result suggests that mutations within exon four of human beta tubulin are rare in newly-diagnosed and recurrent paclitaxel resistant human ovarian cancer...
Epithelioid endometrial and endometrioid stromal tumors: a report of four cases emphasizing their distinction from epithelioid smooth muscle tumors and other oxyphilic uterine and extrauterine tumorsEsther Oliva
James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Int J Gynecol Pathol 21:48-55. 2002..Immunohistochemical evaluation may potentially provide major aid in diagnosis...
Association of clear cell carcinoma of the endometrium with a high rate of venous thromboembolismLisa Lee
Division of Gynecologic Oncology, Biostatistics Center, Massachusetts General Hospital, Boston, USA
J Reprod Med 54:133-8. 2009..To document the rate of clinically significant venous thromboembolism (VTE) in patients with clear cell carcinoma of the endometrium (CCC-E)...
Case records of the Massachusetts General Hospital. Case 17-2008. A 63-year-old man with metastatic renal-cell carcinomaM Dror Michaelson
Division of Hematology-Oncology, Massachusetts General Hospital, Boston, USA
N Engl J Med 358:2389-96. 2008
Stage II endometrioid adenocarcinoma of the endometrium: clinical implications of cervical stromal invasionJorge P Orezzoli
Department of Obstetrics and Gynecology, Tufts Medical Center, Boston, MA, USA
Gynecol Oncol 113:316-23. 2009..However, the impact on prognosis of sub-stages IIA vs IIB is unclear. The purpose of this study was to investigate the prognostic significance of cervical involvement as well as its substaging in patients diagnosed with EEC...
Synergism of epidermal growth factor receptor-targeted immunotherapy with photodynamic treatment of ovarian cancer in vivoMarcela G del Carmen
Wellman Center for Photomedicine, Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA
J Natl Cancer Inst 97:1516-24. 2005..2% to 44%]) groups. CONCLUSION: A mechanistically nonoverlapping combination modality consisting of receptor tyrosine kinase inhibition with C225 and BPD-PDT is well tolerated, effective, and synergistic in mice...
Uterine smooth-muscle tumors with unusual growth patterns: imaging with pathologic correlationDaniel T Cohen
Department of Radiology, Massachusetts General Hospital, 55 Fruit St, White 270, Boston, MA 02114, USA
AJR Am J Roentgenol 188:246-55. 2007..In the appropriate clinical setting, the radiologist should include these unusual lesions in the broader differential diagnosis of smooth-muscle tumors and, in certain cases, aid in surgical planning...
Recommendations for the reporting of fallopian tube neoplasmsTeri A Longacre
Department of Pathology, Stanford University, Stanford, CA 94305, USA
Hum Pathol 38:1160-3. 2007....
Upregulation of MUC4 in cervical squamous cell carcinoma: pathologic significanceElizabeth G Munro
Vincent Center for Reproductive Biology, Vincent Obstetrics and Gynecology Service, Massachusetts General Hospital, Boston, MA, USA
Int J Gynecol Pathol 28:127-33. 2009..Further studies may elucidate the role of MUC4 in the development of squamous cell cervical cancer...
Reclassification of a tubal leiomyosarcoma as an eGIST by molecular evaluation of c-KITRosemary Foster
Division of Hematology Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
Gynecol Oncol 101:363-6. 2006..eGISTs are often histologically confused with leiomyosarcoma. Distinction between eGIST and leiomyosarcoma is critical because of the unique responsiveness of eGISTs to the molecularly targeted agent imatinib...
Smooth muscle tumors of the uterus: a practical approachGemma Toledo
Department of Pathology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
Arch Pathol Lab Med 132:595-605. 2008....
p16 expression in squamous and trophoblastic lesions of the upper female genital tractIvy Chew
Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
Int J Gynecol Pathol 29:513-22. 2010..Thus, when considering the differential diagnosis of cervical SCC and trophoblastic lesions, only strong diffuse p16 staining should be considered helpful...
Potential utility of uroplakin III, thrombomodulin, high molecular weight cytokeratin, and cytokeratin 20 in noninvasive, invasive, and metastatic urothelial (transitional cell) carcinomasDouglas C Parker
Department of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA
Am J Surg Pathol 27:1-10. 2003..The results of the study indicate a role for an antibody panel that includes UROIII, THR, HMWCK, and CK20 in the diagnosis of urothelial tumors...
Endometrial stromal sarcomas: a review of potential prognostic factorsIvy Chew
Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
Adv Anat Pathol 17:113-21. 2010..The impact of other prognostic factors on survival is unclear or controversial, especially in patients with stage I tumors...
Loss of cables, a novel gene on chromosome 18q, in ovarian cancerQun Dong
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Mod Pathol 16:863-8. 2003..In conclusion, our results indicate that loss of Cables is common in ovarian serous and endometrioid carcinomas and imply that Cables may be involved in the pathogenesis of these two types of ovarian carcinomas...
Hepatocyte paraffin 1 antibody does not distinguish primary ovarian tumors with hepatoid differentiation from metastatic hepatocellular carcinomaMartha B Pitman
James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Int J Gynecol Pathol 23:58-64. 2004..Hepatocyte paraffin 1, however, is not useful in distinguishing metastatic hepatocellular carcinoma from primary ovarian hepatoid carcinoma or hepatoid yolk sac tumor...
Case records of the Massachusetts General Hospital. Case 13-2007. A 46-year-old woman with gynecologic and intestinal cancersMichael V Seiden
Department of Medicine, Massachusetts General Hospital, USA
N Engl J Med 356:1760-9. 2007
Calretinin: diagnostic utility in the female genital tractRaquel Portugal
Massachusetts General Hospital, 55 Fruit Street, Boston, MA, USA
Adv Anat Pathol 16:118-24. 2009....
Interobserver reproducibility in the diagnosis of invasive micropapillary carcinoma of the urinary tract among urologic pathologistsAnkur R Sangoi
Department of Pathology, Stanford University, Stanford, CA, USA
Am J Surg Pathol 34:1367-76. 2010..These findings suggest that more study of IMPC is needed to identify the individual pathologic features that might potentially correlate with an aggressive outcome and response to intravesical therapy...
Paclitaxel and platinum chemotherapy for malignant mixed müllerian tumors of the ovaryLinda R Duska
Vincent Gynecology Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Gynecol Oncol 85:459-63. 2002..The current study was undertaken to characterize a group of patients treated as if they had aggressive epithelial ovarian tumors, with cytoreductive surgery and combination paclitaxel/platinum chemotherapy...
Clinical significance of placental examination in perinatal medicineDrucilla J Roberts
Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
J Matern Fetal Neonatal Med 19:255-64. 2006..This review will focus on the utility of the placental examination for fetal and maternal well-being. This review will be restricted to singleton births...
WT1 expression in the female genital tractCarmen Bárcena
Pathology Department, Massachusetts General Hospital, Boston, USA
Adv Anat Pathol 18:454-65. 2011....
Malignant tumors of the female pelvic floor: self-assessment moduleSusanna I Lee
Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, White 270, Boston, MA 02114, USA
AJR Am J Roentgenol 196:S24-7. 2011....
Choriocarcinoma involving the pancreas as first manifestation of a metastatic regressing mixed testicular germ cell tumorLan Wang
Department of Pathology, Harvard Medical School, Boston, MA 02114, USA
Mod Pathol 17:1573-80. 2004..Subsequent resection of the testicular mass confirmed the presence of a cystic and scarring (regressing) mixed germ cell tumor but without evidence of choriocarcinoma...
Unusual endocervical adenocarcinomas: an immunohistochemical analysis with molecular detection of human papillomavirusKay J Park
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York Presbyterian Hospital Weill Cornell Medical Center, New York, NY, USA
Am J Surg Pathol 35:633-46. 2011..The goal of our study was to determine the HPV status and immunohistochemical profiles of unusual histologic subtypes of endocervical adenocarcinoma...
Distinct molecular alterations in complex endometrial hyperplasia (CEH) with and without immature squamous metaplasia (squamous morules)Elena F Brachtel
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
Am J Surg Pathol 29:1322-9. 2005..In our series, cases of CEH-A with SM and beta-catenin alterations appeared to have a less aggressive behavior when compared with CEH-A without SM and with K-ras and PTEN mutations...
Endometrial cancer is a receptor-mediated target for Mullerian Inhibiting SubstanceElizabeth J Renaud
Pediatric Surgical Research Laboratories, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
Proc Natl Acad Sci U S A 102:111-6. 2005..This work broadens the scope of tumors that MIS can potentially control and, by elucidating the MIS signaling pathway, identifies other potential avenues for intervention...
Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometriumNelson A Arango
Pediatric Surgical Research Laboratories CPZN6202, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge St, Boston, MA 02114, USA
Dev Biol 288:276-83. 2005..These results describe the first molecular evidence linking disruption of beta-catenin expression in mesenchymal cells with a switch from myogenesis to adipogenesis in vivo...
Recommendations for the reporting of fallopian tube neoplasmsTeri A Longacre
Department of Pathology, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
Virchows Arch 450:25-9. 2007
Nonendometrioid endometrial carcinomasDiana Lim
Pathology Department, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Semin Diagn Pathol 27:241-60. 2010....
Borderline ovarian tumors: diverse contemporary viewpoints on terminology and diagnostic criteria with illustrative imagesJeffrey D Seidman
Department of Pathology, Washington Hospital Center, Washington DC 20010, USA
Hum Pathol 35:918-33. 2004..For those issues where there is disagreement, the terminology and diagnostic approaches reflecting the differing views are presented...
HMGA2 rearrangement in a case of vulvar aggressive angiomyxomaJoseph T Rabban
Department of Pathology, University of California, San Francisco, 94193, USA
Int J Gynecol Pathol 25:403-7. 2006..HMGA2 involvement has also been described in a variety of benign gynecologic mesenchymal neoplasms. We report an additional case of HMGA2 rearrangement in vulvar aggressive angiomyxoma, using fluorescence in situ hybridization...
Nephrogenic adenoma: an update on an innocuous but troublesome entityAliyah Rahemtullah
Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Adv Anat Pathol 13:247-55. 2006..Clinicopathologic correlation with careful attention to morphology remains the pillar in establishing the correct diagnosis...
Protocol for the examination of specimens from patients with invasive carcinomas of the appendixJoseph Misdraji
Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
Arch Pathol Lab Med 130:1433-9. 2006
A renal cell carcinoma with components of both chromophobe and papillary carcinomaMichael H A Roehrl
Department of Pathology and Laboratory Medicine, James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Warren 2, 55 Fruit Street, Boston, MA 02114, USA
Virchows Arch 450:93-101. 2007..This case illustrates the rare coexistence of two distinct and admixed histologic types of renal cell carcinoma...
Case records of the Massachusetts General Medicine. Weekly clinicopathological exercises. Case 9-2003. An 18-year-old man with back and leg pain and a nondiagnostic biopsy specimenAlison M Friedmann
Department of Pediatric Hematology/Oncology, Massachusetts General Hospital, Boston, USA
N Engl J Med 348:1150-8. 2003
Case records of the Massachusetts General Hospital. Case 18-2005. A 45-year-old woman with a painful mass in the abdomenMichael G Muto
Division of Gynecologic Oncology, Gillette Center for Women's Cancers, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, USA
N Engl J Med 352:2535-42. 2005
Immunoprofile of ovarian tumors with putative transitional cell (urothelial) differentiation using novel urothelial markers: histogenetic and diagnostic implicationsSanjay Logani
Emory University School of Medicine, Atlanta, Georgia 30322, USA
Am J Surg Pathol 27:1434-41. 2003..They also indicate that the morphologic similarity between TCC-O and TCC-B does not indicate any histogenic similarity and, as others have noted, TCC-O is a variant morphology in the spectrum of surface epithelial carcinomas...
Expression of alpha-methylacyl-CoA racemase (P504S) in nephrogenic adenoma: a significant immunohistochemical pitfall compounding the differential diagnosis with prostatic adenocarcinomaBrian F Skinnider
Department of Pathology, Vancouver Hospital and Health Sciences Center and University of British Columbia, Vancouver, BC, Canada
Am J Surg Pathol 28:701-5. 2004....
Immunohistochemistry as a tool in the differential diagnosis of ovarian tumors: an updatePatricia M Baker
Pathology Department, Health Sciences Centre, Winnipeg, Canada
Int J Gynecol Pathol 24:39-55. 2005..The uses of OCT-4 (POU5F1) (a new highly sensitive and specific marker of dysgerminoma and embryonal carcinoma), CD30, and c-kit are also discussed...
Prostatic tissue in mature cystic teratomas of the ovary: a report of four cases, including one with features of prostatic adenocarcinoma, and cytogenetic studiesMilad Halabi
Department of Pathology, General Hospital of Ried, Austria
Int J Gynecol Pathol 21:261-7. 2002..A small number of cases of prostatic tissue in ovarian teratomas have previously been documented but none had morphologic features of carcinoma...
Unusual morphologic features of endometrial stromal tumors: a report of 2 casesPatricia M Baker
Pathology Department, Health Sciences Centre, Winnipeg, Canada
Am J Surg Pathol 29:1394-8. 2005..The differential diagnosis in the first case included cellular intravenous leiomyomatosis/lipoleiomyomatosis with skeletal muscle differentiation; and in the second case, a cellular smooth muscle tumor with bizarre nuclei was considered...
Endometrial stromal tumours of the uterus: a practical approach using conventional morphology and ancillary techniquesPatricia Baker
Pathology Department, Health Sciences Centre, Winnipeg, Manitoba, Canada
J Clin Pathol 60:235-43. 2007..A practical approach is provided for the diagnosis of ESTs on the basis of systematic assessment of histological and immunohistochemical parameters, and recent developments related to these tumours are highlighted...
Use of histone deacetylase 8 (HDAC8), a new marker of smooth muscle differentiation, in the classification of mesenchymal tumors of the uterusLaurence de Leval
Department of Pathology, Center for Experimental Cancer Research, University of Liege, Liege, Belgium
Am J Surg Pathol 30:319-27. 2006..Thus, HDAC8 detection may be useful in helping the differential diagnosis of uterine mesenchymal tumors...
Administration of recombinant human erythropoietin alpha before autologous stem cell transplantation reduces transfusion requirement in multiple myeloma patientsMassimo Martino
Bone Marrow Transplantation Unit, Azienda Ospedaliera Bianchi-Melacrino-Morelli, 89100, Reggio, Calabria, Italy
Support Care Cancer 13:182-7. 2005..008). Independently of Hb levels at PBSCT, rHuEPO therapy was significantly associated with a lower risk of transfusion requirement. In conclusion, rHuEPO is shown to be effective when administered prior to high-dose therapy in MM...
Use of novel immunohistochemical markers expressed in colonic adenocarcinoma to distinguish primary ovarian tumors from metastatic colorectal carcinomaSanjay Logani
Emory University School of Medicine, Atlanta, GA, USA
Mod Pathol 18:19-25. 2005..Diffuse expression of all three markers (CDX2, beta-catenin and P504S) in a tumor in the ovary was found to be virtually diagnostic of metastasis from a colorectal primary in this study...
Placental histopathologic features in patients with thrombophilic mutationsMaria Rosaria Raspollini
Department of Human Pathology and Oncology, University of Florence School of Medicine, Florence, Italy
J Matern Fetal Neonatal Med 20:113-23. 2007..This may assist clinicians in their consultation with patients and optimize management in future pregnancies...
A practical approach to intraoperative consultation in gynecological pathologyPatricia Baker
Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
Int J Gynecol Pathol 27:353-65. 2008..Lastly, intraoperative evaluation of lymph nodes including the role of sentinel lymph nodes is discussed...
Hepsin colocalizes with desmosomes and induces progression of ovarian cancer in a mouse modelJiangyong Miao
Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA
Int J Cancer 123:2041-7. 2008..The ability of ectopic hepsin to induce tumor growth in mice is abrogated by the mutation of 3 critical residues in the catalytic domain, thus implicating the enzymatic activity of hepsin in promoting tumor progression...
