Esther Oliva

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Mixed tumors of the vagina: an immunohistochemical study of 13 cases with emphasis on the cell of origin and potential aid in differential diagnosis
    Esther Oliva
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Mod Pathol 17:1243-50. 2004
  2. ncbi request reprint CD10 expression in the female genital tract: does it have useful diagnostic applications?
    Esther Oliva
    Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Adv Anat Pathol 11:310-5. 2004
  3. doi request reprint Immunohistochemistry as an adjunct in the differential diagnosis of radiation-induced atypia versus urothelial carcinoma in situ of the bladder: a study of 45 cases
    Esther Oliva
    Pathology Department, Massachusetts General Hospital, Boston, MA 02118, USA
    Hum Pathol 44:860-6. 2013
  4. ncbi request reprint High frequency of JAZF1-JJAZ1 gene fusion in endometrial stromal tumors with smooth muscle differentiation by interphase FISH detection
    Esther Oliva
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Surg Pathol 31:1277-84. 2007
  5. ncbi request reprint CD10 expression in pure stromal and sex cord-stromal tumors of the ovary: an immunohistochemical analysis of 101 cases
    Esther Oliva
    Pathology Department, Massachusetts General Hospital, Boston, MA 02114, USA
    Int J Gynecol Pathol 26:359-67. 2007
  6. ncbi request reprint Sertoli cell tumors of the ovary: a clinicopathologic and immunohistochemical study of 54 cases
    Esther Oliva
    James Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 29:143-56. 2005
  7. ncbi request reprint An immunohistochemical analysis of endometrial stromal and smooth muscle tumors of the uterus: a study of 54 cases emphasizing the importance of using a panel because of overlap in immunoreactivity for individual antibodies
    Esther Oliva
    James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Surg Pathol 26:403-12. 2002
  8. ncbi request reprint Clear cell carcinoma of the urinary bladder: a report and comparison of four tumors of mullerian origin and nine of probable urothelial origin with discussion of histogenesis and diagnostic problems
    Esther Oliva
    James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Fruit Street, Boston, MA 02114, USA
    Am J Surg Pathol 26:190-7. 2002
  9. doi request reprint Clinicopathological and molecular analysis of endometrial carcinoma associated with tamoxifen
    Julia Turbiner
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Mod Pathol 21:925-36. 2008
  10. doi request reprint Decreased survival in EGFR gene amplified vulvar carcinoma
    Whitfield B Growdon
    Vincent Center for Reproductive Biology, Vincent Obstetrics and Gynecology Service, Massachusetts General Hospital, THR 901A, 55 Fruit Street, Boston, Massachusetts 02114, USA
    Gynecol Oncol 111:289-97. 2008

Detail Information

Publications89

  1. ncbi request reprint Mixed tumors of the vagina: an immunohistochemical study of 13 cases with emphasis on the cell of origin and potential aid in differential diagnosis
    Esther Oliva
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Mod Pathol 17:1243-50. 2004
    ..MTsV are positive for h-Caldesmon and CD10, two markers that have been used in gynecologic pathology primarily to aid in establishing the smooth muscle or endometrial stromal phenotype of a neoplasm...
  2. ncbi request reprint CD10 expression in the female genital tract: does it have useful diagnostic applications?
    Esther Oliva
    Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Adv Anat Pathol 11:310-5. 2004
    ....
  3. doi request reprint Immunohistochemistry as an adjunct in the differential diagnosis of radiation-induced atypia versus urothelial carcinoma in situ of the bladder: a study of 45 cases
    Esther Oliva
    Pathology Department, Massachusetts General Hospital, Boston, MA 02118, USA
    Hum Pathol 44:860-6. 2013
    ..Our data suggest that a CK20(-) p53(-) CD44a panel proves to be very helpful (CK20 more reliable than p53 or CD44s) in the diagnosis of RAD-Ch...
  4. ncbi request reprint High frequency of JAZF1-JJAZ1 gene fusion in endometrial stromal tumors with smooth muscle differentiation by interphase FISH detection
    Esther Oliva
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Surg Pathol 31:1277-84. 2007
    ..Our results indicate that the detection of this chromosomal abnormality can be used to diagnose ESTs with smooth muscle differentiation when the smooth muscle component is predominant...
  5. ncbi request reprint CD10 expression in pure stromal and sex cord-stromal tumors of the ovary: an immunohistochemical analysis of 101 cases
    Esther Oliva
    Pathology Department, Massachusetts General Hospital, Boston, MA 02114, USA
    Int J Gynecol Pathol 26:359-67. 2007
    ..CD10 may play a useful role in aiding the differential between endometrial stromal tumors in the ovary and SCST and stromal tumors...
  6. ncbi request reprint Sertoli cell tumors of the ovary: a clinicopathologic and immunohistochemical study of 54 cases
    Esther Oliva
    James Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 29:143-56. 2005
    ..The tumors typically occur in young females, sometimes children who typically present with sexual precocity, and occasional patients have Peutz-Jeghers syndrome...
  7. ncbi request reprint An immunohistochemical analysis of endometrial stromal and smooth muscle tumors of the uterus: a study of 54 cases emphasizing the importance of using a panel because of overlap in immunoreactivity for individual antibodies
    Esther Oliva
    James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Surg Pathol 26:403-12. 2002
    ..8) CD34, CD99, and keratin have no or minimal role in this area, but keratin positivity in smooth muscle tumors should not lead to their confusion with epithelial tumors...
  8. ncbi request reprint Clear cell carcinoma of the urinary bladder: a report and comparison of four tumors of mullerian origin and nine of probable urothelial origin with discussion of histogenesis and diagnostic problems
    Esther Oliva
    James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Fruit Street, Boston, MA 02114, USA
    Am J Surg Pathol 26:190-7. 2002
    ....
  9. doi request reprint Clinicopathological and molecular analysis of endometrial carcinoma associated with tamoxifen
    Julia Turbiner
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Mod Pathol 21:925-36. 2008
    ..In conclusion, there was a direct relationship between tamoxifen exposure and overexpression of beta-catenin oncoprotein, which is known to play a major role in the pathogenesis of estrogen-driven, type I endometrial adenocarcinoma...
  10. doi request reprint Decreased survival in EGFR gene amplified vulvar carcinoma
    Whitfield B Growdon
    Vincent Center for Reproductive Biology, Vincent Obstetrics and Gynecology Service, Massachusetts General Hospital, THR 901A, 55 Fruit Street, Boston, Massachusetts 02114, USA
    Gynecol Oncol 111:289-97. 2008
    ....
  11. ncbi request reprint Primary endometrioid stromal sarcoma of the ovary: a clinicopathologic study of 27 cases with morphologic and behavioral features similar to those of uterine low-grade endometrial stromal sarcoma
    Esther Oliva
    James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Department of Pathology, Harvard Medical School, Boston, MA Viollier Weintraub Laboratory, Pathology Department, Geneva, Switzerland
    Am J Surg Pathol 38:305-15. 2014
    ..When a primary ovarian origin is determined, the differential diagnosis is most often with a sex cord-stromal tumor, particularly a granulosa cell tumor because of a diffuse growth of cells with scant cytoplasm...
  12. ncbi request reprint Uterine tumors resembling ovarian sex cord tumors (UTROSCT) lack the JAZF1-JJAZ1 translocation frequently seen in endometrial stromal tumors
    Paul N Staats
    Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Surg Pathol 33:1206-12. 2009
    ....
  13. ncbi request reprint Frequency of known gene rearrangements in endometrial stromal tumors
    Sarah Chiang
    Department of Pathology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Am J Surg Pathol 35:1364-72. 2011
    ..The presence of identical gene rearrangements in both uterine and extrauterine ESTs suggests a similar pathogenesis. The presence of detectable gene rearrangements in uterine ESS may predict better patient outcome...
  14. doi request reprint Recent developments in uterine mesenchymal neoplasms
    Sarah Chiang
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Histopathology 62:124-37. 2013
    ..In this review, we discuss the core updates in the diagnosis and classification of uterine leiomyosarcomas and endometrial stromal sarcomas, highlighting new and important molecular genetic findings that may drive pathogenesis...
  15. doi request reprint Mullerian adenosarcomas: an immunophenotypic analysis of 35 cases
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 32:1013-21. 2008
    ..ER, PR, and CD10 expression was lost in MA-SOs relative to conventional low-grade stromal areas of mullerian/mesodermal adenosarcomas, reflecting the "dedifferentiation" of this component...
  16. ncbi request reprint Mechanisms of Cables 1 gene inactivation in human ovarian cancer development
    Hideo Sakamoto
    Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachussetts 02114, USA
    Cancer Biol Ther 7:180-88. 2008
    ..Together these findings suggest that multiple mechanisms underlie the loss of Cables 1 expression in ovarian cancer cells, supporting the hypothesis that Cables 1 is a tumor suppressor in human ovarian cancer...
  17. pmc The Li-Fraumeni syndrome (LFS): a model for the initiation of p53 signatures in the distal Fallopian tube
    Wa Xian
    Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Pathol 220:17-23. 2010
    ..This is in keeping with a general model of carcinogenesis, in which different and often independent risk factors operate at multiple points in the serous carcinogenic spectrum...
  18. ncbi request reprint Case records of the Massachusetts General Hospital. Case 11-2006. A 54-year-old woman with a mass in the pelvis
    Carolyn N Krasner
    Gillette Center for Women s Cancers, Massachusetts General Hospital, USA
    N Engl J Med 354:1615-25. 2006
  19. ncbi request reprint Functional analyses of the cancer stem cell-like properties of human endometrial tumor initiating cells
    Anne M Friel
    Vincent Center for Reproductive Biology, Vincent Obstetrics and Gynecology Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Cell Cycle 7:242-9. 2008
    ..Additionally, we identified SP fractions in primary EnCa. Together these results are consistent with the hypothesis that EnCa contain a subpopulation of tumor initiating cells with stem like properties...
  20. ncbi request reprint Uterine tumors resembling ovarian sex cord tumors: an ultrastructural analysis of 13 cases
    Mamta Gupta
    Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
    Ultrastruct Pathol 34:16-24. 2010
    ....
  21. ncbi request reprint Influence of histologic criteria and confounding factors in staging equivocal cases for microscopic perivesical tissue invasion (pT3a): an interobserver study among genitourinary pathologists
    Vijayalakshmi Ananthanarayanan
    Department of Pathology, University of Chicago, Chicago, IL Department of Biostatistics and Bioinformatics, Rollins School of Public Health Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN Department of Pathology, Johns Hopkins Hospital, Baltimore, MD Department of Pathology, University of California, San Diego, CA Division of Anatomic Pathology, Mayo Clinic, Rochester, MN Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH Department of Pathology, Massachusetts General Hospital, Boston, MA Department of Pathology, MD Anderson Cancer Center Department of Pathology, Methodist Hospital, Houston, TX Department of Pathology, Memorial Sloan Kettering Cancer Center, New York Department of Pathology, University of Rochester Medical Center, Rochester, NY Section of Pathological Anatomy, Polytechnic University of the Marche Region, Ancona, Italy Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada Department of Pathology, Nagoya Daini Red Cross Hospital, Nagoya
    Am J Surg Pathol 38:167-75. 2014
    ..This study highlights the need to adopt common criteria in defining the outer MP boundary. Future studies may identify the most clinically relevant histoanatomic criteria for MPVTI. ..
  22. ncbi request reprint Clinicopathologic analysis of 187 high-grade endometrial carcinomas of different histologic subtypes: similar outcomes belie distinctive biologic differences
    Robert A Soslow
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 31:979-87. 2007
    ....
  23. ncbi request reprint Pathogenetic pathways in ovarian endometrioid adenocarcinoma: a molecular study of 29 cases
    Julia Turbiner Geyer
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Surg Pathol 33:1157-63. 2009
    ..On the basis of these results, we suggest that there may also be a dual pathogenetic pathway for EOC...
  24. ncbi request reprint Defining the extent of cables loss in endometrial cancer subtypes and its effectiveness as an inhibitor of cell proliferation in malignant endometrial cells in vitro and in vivo
    Robert L DeBernardo
    Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Cancer Biol Ther 4:103-7. 2005
    ..Collectively these results suggest that Cables is an important regulator of cell proliferation and loss of Cables expression contributes to the development of all types of EC...
  25. ncbi request reprint Uterine malignant mixed mullerian tumors should not be included in studies of endometrial carcinoma
    Ami P Vaidya
    Division of Gynecologic Oncology, Gillette Center for Women s Cancers, Massachusetts General Hospital, Boston, MA 02114, USA
    Gynecol Oncol 103:684-7. 2006
    ..The current study was undertaken to compare outcomes, stage for stage, of uterine MMMT with poor prognosis endometrial adenocarcinomas...
  26. pmc A role for BRCA1 in uterine leiomyosarcoma
    Deyin Xing
    Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Cancer Res 69:8231-5. 2009
    ..These data indicate that the loss of BRCA1 function may be an important step in the progression of ULMS. Our findings provide a rationale for investigating therapies that target BRCA1 deficiency in ULMS...
  27. doi request reprint Cytogenetic and molecular aberrations in endometrial stromal tumors
    Sarah Chiang
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Hum Pathol 42:609-17. 2011
    ..In this review, we summarize the recent advances in the molecular pathology of endometrial stromal tumors...
  28. doi request reprint Morphologic spectrum of immunohistochemically characterized clear cell carcinoma of the ovary: a study of 155 cases
    Deborah DeLair
    Department of Pathology, Memorial Sloan Kettering Cancer Center, Vancouver General Hospital, NY, USA
    Am J Surg Pathol 35:36-44. 2011
    ..Clear cell-rich tumors with features that depart from the classical morphologic appearances described herein should suggest the possibility of an alternative diagnosis...
  29. ncbi request reprint Endometrial stromal nodules and endometrial stromal tumors with limited infiltration: a clinicopathologic study of 50 cases
    Adriana Dionigi
    James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Surg Pathol 26:567-81. 2002
    ....
  30. ncbi request reprint Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: a study in serial samples
    Richard T Penson
    Division of Hematology Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Gynecol Oncol 93:98-106. 2004
    ....
  31. doi request reprint Interobserver agreement for assessing invasion in stage 1A vulvar squamous cell carcinoma
    Amal Abdel-Mesih
    Department of Pathology and Molecular Medicine Department of Pathology and Molecular Medicine, Juravinski Hospital School of Nursing Department of Clinical Epidemiology and Biostatistics Department of Pathology and Molecular Medicine, McMaster University Medical Centre, McMaster University, Hamilton Department of Pathology, St Joseph s Hospital Department of Pathology, Mt Sinai Hospital, University of Toronto, Toronto, ON British Columbia Cancer Agency, University of British Columbia, Vancouver, BC, Canada Department of Pathology, Brigham and Women s Hospital Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
    Am J Surg Pathol 37:1336-41. 2013
    ....
  32. ncbi request reprint The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor
    Cheng Han Lee
    Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
    Am J Surg Pathol 36:641-53. 2012
    ..Thus, their distinction from typical JAZF1 ESS is important for prognostic and therapeutic purposes...
  33. doi request reprint Solid pseudopapillary neoplasm of the ovary: a report of 3 primary ovarian tumors resembling those of the pancreas
    Vikram Deshpande
    Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Am J Surg Pathol 34:1514-20. 2010
    ..The morphologic and immunohistochemical similarity to pancreatic solid pseudopapillary neoplasm facilitates the accurate diagnosis of this rare ovarian neoplasm...
  34. ncbi request reprint Smooth muscle tumors of the ovary: a clinicopathologic study of 54 cases emphasizing prognostic criteria, histologic variants, and differential diagnosis
    Melinda F Lerwill
    James Homer Wright Pathology Laboratories of the Massachusetts General Hospital and the Department of Pathology, Harvard Medical School, Boston, MA 021114, USA
    Am J Surg Pathol 28:1436-51. 2004
    ..The main tumors in the differential diagnosis are those in the fibroma/thecoma category, spindle cell carcinomas, and metastatic gastrointestinal stromal tumors...
  35. doi request reprint Liposarcoma arising in uterine lipoleiomyoma: a report of 3 cases and review of the literature
    Anna Greene McDonald
    Department of Pathology, Massachusetts General Hospital, Boston, 02114, USA
    Am J Surg Pathol 35:221-7. 2011
    ..Most uterine sarcomas arise de novo, with malignant transformation of a benign mesenchymal tumor being a very rare event, and is reported only in leiomyomata...
  36. doi request reprint Histopathologic prognostic factors in stage I leiomyosarcoma of the uterus: a detailed analysis of 27 cases
    Wei Lien Wang
    Massachusetts General Hospital, Boston, MA, USA
    Am J Surg Pathol 35:522-9. 2011
    ....
  37. ncbi request reprint Case records of the Massachusetts General Hospital. Case 13-2007. A 46-year-old woman with gynecologic and intestinal cancers
    Michael V Seiden
    Department of Medicine, Massachusetts General Hospital, USA
    N Engl J Med 356:1760-9. 2007
  38. ncbi request reprint Interobserver reproducibility in the diagnosis of invasive micropapillary carcinoma of the urinary tract among urologic pathologists
    Ankur R Sangoi
    Department of Pathology, Stanford University, Stanford, CA, USA
    Am J Surg Pathol 34:1367-76. 2010
    ..These findings suggest that more study of IMPC is needed to identify the individual pathologic features that might potentially correlate with an aggressive outcome and response to intravesical therapy...
  39. ncbi request reprint Molecular profile of grade 3 endometrioid endometrial carcinoma: is it a type I or type II endometrial carcinoma?
    Teresa Alvarez
    The James Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Am J Surg Pathol 36:753-61. 2012
    ....
  40. ncbi request reprint beta tubulin mutations are rare in human ovarian carcinoma
    Diana E Lamendola
    Department of Hematology Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Anticancer Res 23:681-6. 2003
    ..The interaction between paclitaxel and its target, beta tubulin, is essential for effective cytotoxicity. Alterations or mutation of beta tubulin have the potential to alter paclitaxel binding and confer a drug resistant phenotype...
  41. ncbi request reprint Uterine smooth-muscle tumors with unusual growth patterns: imaging with pathologic correlation
    Daniel T Cohen
    Department of Radiology, Massachusetts General Hospital, 55 Fruit St, White 270, Boston, MA 02114, USA
    AJR Am J Roentgenol 188:246-55. 2007
    ..In the appropriate clinical setting, the radiologist should include these unusual lesions in the broader differential diagnosis of smooth-muscle tumors and, in certain cases, aid in surgical planning...
  42. ncbi request reprint Epithelioid endometrial and endometrioid stromal tumors: a report of four cases emphasizing their distinction from epithelioid smooth muscle tumors and other oxyphilic uterine and extrauterine tumors
    Esther Oliva
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Int J Gynecol Pathol 21:48-55. 2002
    ..Immunohistochemical evaluation may potentially provide major aid in diagnosis...
  43. doi request reprint Case records of the Massachusetts General Hospital. Case 17-2008. A 63-year-old man with metastatic renal-cell carcinoma
    M Dror Michaelson
    Division of Hematology Oncology, Massachusetts General Hospital, Boston, USA
    N Engl J Med 358:2389-96. 2008
  44. doi request reprint Stage II endometrioid adenocarcinoma of the endometrium: clinical implications of cervical stromal invasion
    Jorge P Orezzoli
    Department of Obstetrics and Gynecology, Tufts Medical Center, Boston, MA, USA
    Gynecol Oncol 113:316-23. 2009
    ..However, the impact on prognosis of sub-stages IIA vs IIB is unclear. The purpose of this study was to investigate the prognostic significance of cervical involvement as well as its substaging in patients diagnosed with EEC...
  45. ncbi request reprint Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term
    Julia Turbiner
    Pathology Department, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Surg Pathol 31:489-500. 2007
    ....
  46. ncbi request reprint Synergism of epidermal growth factor receptor-targeted immunotherapy with photodynamic treatment of ovarian cancer in vivo
    Marcela G del Carmen
    Wellman Center for Photomedicine, Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA
    J Natl Cancer Inst 97:1516-24. 2005
    ....
  47. ncbi request reprint Association of clear cell carcinoma of the endometrium with a high rate of venous thromboembolism
    Lisa Lee
    Division of Gynecologic Oncology, Biostatistics Center, Massachusetts General Hospital, Boston, USA
    J Reprod Med 54:133-8. 2009
    ..To document the rate of clinically significant venous thromboembolism (VTE) in patients with clear cell carcinoma of the endometrium (CCC-E)...
  48. doi request reprint Endometrial stromal sarcomas: a review of potential prognostic factors
    Ivy Chew
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Adv Anat Pathol 17:113-21. 2010
    ..The impact of other prognostic factors on survival is unclear or controversial, especially in patients with stage I tumors...
  49. ncbi request reprint Calretinin: diagnostic utility in the female genital tract
    Raquel Portugal
    Massachusetts General Hospital, 55 Fruit Street, Boston, MA, USA
    Adv Anat Pathol 16:118-24. 2009
    ....
  50. doi request reprint p16 expression in squamous and trophoblastic lesions of the upper female genital tract
    Ivy Chew
    Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
    Int J Gynecol Pathol 29:513-22. 2010
    ..Thus, when considering the differential diagnosis of cervical SCC and trophoblastic lesions, only strong diffuse p16 staining should be considered helpful...
  51. pmc Upregulation of MUC4 in cervical squamous cell carcinoma: pathologic significance
    Elizabeth G Munro
    Vincent Center for Reproductive Biology, Vincent Obstetrics and Gynecology Service, Massachusetts General Hospital, Boston, MA, USA
    Int J Gynecol Pathol 28:127-33. 2009
    ..Further studies may elucidate the role of MUC4 in the development of squamous cell cervical cancer...
  52. doi request reprint Smooth muscle tumors of the uterus: a practical approach
    Gemma Toledo
    Department of Pathology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    Arch Pathol Lab Med 132:595-605. 2008
    ....
  53. ncbi request reprint Hepatocyte paraffin 1 antibody does not distinguish primary ovarian tumors with hepatoid differentiation from metastatic hepatocellular carcinoma
    Martha B Pitman
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Int J Gynecol Pathol 23:58-64. 2004
    ..Hepatocyte paraffin 1, however, is not useful in distinguishing metastatic hepatocellular carcinoma from primary ovarian hepatoid carcinoma or hepatoid yolk sac tumor...
  54. ncbi request reprint Reclassification of a tubal leiomyosarcoma as an eGIST by molecular evaluation of c-KIT
    Rosemary Foster
    Division of Hematology Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Gynecol Oncol 101:363-6. 2006
    ..eGISTs are often histologically confused with leiomyosarcoma. Distinction between eGIST and leiomyosarcoma is critical because of the unique responsiveness of eGISTs to the molecularly targeted agent imatinib...
  55. ncbi request reprint Loss of cables, a novel gene on chromosome 18q, in ovarian cancer
    Qun Dong
    Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Mod Pathol 16:863-8. 2003
    ..In conclusion, our results indicate that loss of Cables is common in ovarian serous and endometrioid carcinomas and imply that Cables may be involved in the pathogenesis of these two types of ovarian carcinomas...
  56. ncbi request reprint Recommendations for the reporting of fallopian tube neoplasms
    Teri A Longacre
    Department of Pathology, Stanford University, Stanford, CA 94305, USA
    Hum Pathol 38:1160-3. 2007
    ....
  57. ncbi request reprint Potential utility of uroplakin III, thrombomodulin, high molecular weight cytokeratin, and cytokeratin 20 in noninvasive, invasive, and metastatic urothelial (transitional cell) carcinomas
    Douglas C Parker
    Department of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA
    Am J Surg Pathol 27:1-10. 2003
    ..The results of the study indicate a role for an antibody panel that includes UROIII, THR, HMWCK, and CK20 in the diagnosis of urothelial tumors...
  58. ncbi request reprint Paclitaxel and platinum chemotherapy for malignant mixed müllerian tumors of the ovary
    Linda R Duska
    Vincent Gynecology Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Gynecol Oncol 85:459-63. 2002
    ..The current study was undertaken to characterize a group of patients treated as if they had aggressive epithelial ovarian tumors, with cytoreductive surgery and combination paclitaxel/platinum chemotherapy...
  59. ncbi request reprint Clinical significance of placental examination in perinatal medicine
    Drucilla J Roberts
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    J Matern Fetal Neonatal Med 19:255-64. 2006
    ..This review will focus on the utility of the placental examination for fetal and maternal well-being. This review will be restricted to singleton births...
  60. ncbi request reprint Epithelioid angiomyolipoma of the kidney: pathological features and clinical outcome in a series of consecutively resected tumors
    Wenlei He
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Mod Pathol 26:1355-64. 2013
    ....
  61. ncbi request reprint Intestinal-type endocervical adenocarcinoma in situ: an immunophenotypically distinct subset of AIS affecting older women
    Brooke E Howitt
    Department of Pathology, Brigham and Women s Hospital, Division of Women s and Perinatal Pathology, Beth Israel Deaconess Medical Center and Massachusetts General Hospital, Boston, MA, USA
    Am J Surg Pathol 37:625-33. 2013
    ..Awareness that iAIS can show variable staining for p16 and Ki67 is important when resolving problematic endocervical lesions, particularly in small biopsies with unusual p16 staining patterns...
  62. ncbi request reprint Nephrogenic adenoma: an update on an innocuous but troublesome entity
    Aliyah Rahemtullah
    Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Adv Anat Pathol 13:247-55. 2006
    ..Clinicopathologic correlation with careful attention to morphology remains the pillar in establishing the correct diagnosis...
  63. pmc Endometrial cancer is a receptor-mediated target for Mullerian Inhibiting Substance
    Elizabeth J Renaud
    Pediatric Surgical Research Laboratories, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Proc Natl Acad Sci U S A 102:111-6. 2005
    ..This work broadens the scope of tumors that MIS can potentially control and, by elucidating the MIS signaling pathway, identifies other potential avenues for intervention...
  64. ncbi request reprint Choriocarcinoma involving the pancreas as first manifestation of a metastatic regressing mixed testicular germ cell tumor
    Lan Wang
    Department of Pathology, Harvard Medical School, Boston, MA 02114, USA
    Mod Pathol 17:1573-80. 2004
    ..Subsequent resection of the testicular mass confirmed the presence of a cystic and scarring (regressing) mixed germ cell tumor but without evidence of choriocarcinoma...
  65. doi request reprint Malignant tumors of the female pelvic floor: self-assessment module
    Susanna I Lee
    Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, White 270, Boston, MA 02114, USA
    AJR Am J Roentgenol 196:S24-7. 2011
    ....
  66. doi request reprint WT1 expression in the female genital tract
    Carmen Bárcena
    Pathology Department, Massachusetts General Hospital, Boston, USA
    Adv Anat Pathol 18:454-65. 2011
    ....
  67. ncbi request reprint Distinct molecular alterations in complex endometrial hyperplasia (CEH) with and without immature squamous metaplasia (squamous morules)
    Elena F Brachtel
    Department of Pathology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Am J Surg Pathol 29:1322-9. 2005
    ..In our series, cases of CEH-A with SM and beta-catenin alterations appeared to have a less aggressive behavior when compared with CEH-A without SM and with K-ras and PTEN mutations...
  68. doi request reprint Unusual endocervical adenocarcinomas: an immunohistochemical analysis with molecular detection of human papillomavirus
    Kay J Park
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York Presbyterian Hospital Weill Cornell Medical Center, New York, NY, USA
    Am J Surg Pathol 35:633-46. 2011
    ..The goal of our study was to determine the HPV status and immunohistochemical profiles of unusual histologic subtypes of endocervical adenocarcinoma...
  69. ncbi request reprint Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium
    Nelson A Arango
    Pediatric Surgical Research Laboratories CPZN6202, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge St, Boston, MA 02114, USA
    Dev Biol 288:276-83. 2005
    ..These results describe the first molecular evidence linking disruption of beta-catenin expression in mesenchymal cells with a switch from myogenesis to adipogenesis in vivo...
  70. ncbi request reprint Recommendations for the reporting of fallopian tube neoplasms
    Teri A Longacre
    Department of Pathology, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA
    Virchows Arch 450:25-9. 2007
  71. ncbi request reprint Borderline ovarian tumors: diverse contemporary viewpoints on terminology and diagnostic criteria with illustrative images
    Jeffrey D Seidman
    Department of Pathology, Washington Hospital Center, Washington DC 20010, USA
    Hum Pathol 35:918-33. 2004
    ..For those issues where there is disagreement, the terminology and diagnostic approaches reflecting the differing views are presented...
  72. ncbi request reprint HMGA2 rearrangement in a case of vulvar aggressive angiomyxoma
    Joseph T Rabban
    Department of Pathology, University of California, San Francisco, 94193, USA
    Int J Gynecol Pathol 25:403-7. 2006
    ..HMGA2 involvement has also been described in a variety of benign gynecologic mesenchymal neoplasms. We report an additional case of HMGA2 rearrangement in vulvar aggressive angiomyxoma, using fluorescence in situ hybridization...
  73. ncbi request reprint Nonendometrioid endometrial carcinomas
    Diana Lim
    Pathology Department, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Semin Diagn Pathol 27:241-60. 2010
    ....
  74. ncbi request reprint Protocol for the examination of specimens from patients with invasive carcinomas of the appendix
    Joseph Misdraji
    Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Pathol Lab Med 130:1433-9. 2006
  75. ncbi request reprint Case records of the Massachusetts General Medicine. Weekly clinicopathological exercises. Case 9-2003. An 18-year-old man with back and leg pain and a nondiagnostic biopsy specimen
    Alison M Friedmann
    Department of Pediatric Hematology Oncology, Massachusetts General Hospital, Boston, USA
    N Engl J Med 348:1150-8. 2003
  76. ncbi request reprint Case records of the Massachusetts General Hospital. Case 18-2005. A 45-year-old woman with a painful mass in the abdomen
    Michael G Muto
    Division of Gynecologic Oncology, Gillette Center for Women s Cancers, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, USA
    N Engl J Med 352:2535-42. 2005
  77. ncbi request reprint A renal cell carcinoma with components of both chromophobe and papillary carcinoma
    Michael H A Roehrl
    Department of Pathology and Laboratory Medicine, James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Warren 2, 55 Fruit Street, Boston, MA 02114, USA
    Virchows Arch 450:93-101. 2007
    ..This case illustrates the rare coexistence of two distinct and admixed histologic types of renal cell carcinoma...
  78. ncbi request reprint Prostatic tissue in mature cystic teratomas of the ovary: a report of four cases, including one with features of prostatic adenocarcinoma, and cytogenetic studies
    Milad Halabi
    Department of Pathology, General Hospital of Ried, Austria
    Int J Gynecol Pathol 21:261-7. 2002
    ..A small number of cases of prostatic tissue in ovarian teratomas have previously been documented but none had morphologic features of carcinoma...
  79. pmc Endometrial stromal tumours of the uterus: a practical approach using conventional morphology and ancillary techniques
    Patricia Baker
    Pathology Department, Health Sciences Centre, Winnipeg, Manitoba, Canada
    J Clin Pathol 60:235-43. 2007
    ..A practical approach is provided for the diagnosis of ESTs on the basis of systematic assessment of histological and immunohistochemical parameters, and recent developments related to these tumours are highlighted...
  80. ncbi request reprint Immunoprofile of ovarian tumors with putative transitional cell (urothelial) differentiation using novel urothelial markers: histogenetic and diagnostic implications
    Sanjay Logani
    Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Am J Surg Pathol 27:1434-41. 2003
    ..They also indicate that the morphologic similarity between TCC-O and TCC-B does not indicate any histogenic similarity and, as others have noted, TCC-O is a variant morphology in the spectrum of surface epithelial carcinomas...
  81. ncbi request reprint Expression of alpha-methylacyl-CoA racemase (P504S) in nephrogenic adenoma: a significant immunohistochemical pitfall compounding the differential diagnosis with prostatic adenocarcinoma
    Brian F Skinnider
    Department of Pathology, Vancouver Hospital and Health Sciences Center and University of British Columbia, Vancouver, BC, Canada
    Am J Surg Pathol 28:701-5. 2004
    ....
  82. ncbi request reprint Use of histone deacetylase 8 (HDAC8), a new marker of smooth muscle differentiation, in the classification of mesenchymal tumors of the uterus
    Laurence de Leval
    Department of Pathology, Center for Experimental Cancer Research, University of Liege, Liege, Belgium
    Am J Surg Pathol 30:319-27. 2006
    ..CD10 was expressed in most ESTs (14 of 17), but it was also positive in 15 of 45 SMTs...
  83. ncbi request reprint Immunohistochemistry as a tool in the differential diagnosis of ovarian tumors: an update
    Patricia M Baker
    Pathology Department, Health Sciences Centre, Winnipeg, Canada
    Int J Gynecol Pathol 24:39-55. 2005
    ..The uses of OCT-4 (POU5F1) (a new highly sensitive and specific marker of dysgerminoma and embryonal carcinoma), CD30, and c-kit are also discussed...
  84. ncbi request reprint Unusual morphologic features of endometrial stromal tumors: a report of 2 cases
    Patricia M Baker
    Pathology Department, Health Sciences Centre, Winnipeg, Canada
    Am J Surg Pathol 29:1394-8. 2005
    ..The differential diagnosis in the first case included cellular intravenous leiomyomatosis/lipoleiomyomatosis with skeletal muscle differentiation; and in the second case, a cellular smooth muscle tumor with bizarre nuclei was considered...
  85. ncbi request reprint Placental histopathologic features in patients with thrombophilic mutations
    Maria Rosaria Raspollini
    Department of Human Pathology and Oncology, University of Florence School of Medicine, Florence, Italy
    J Matern Fetal Neonatal Med 20:113-23. 2007
    ..This may assist clinicians in their consultation with patients and optimize management in future pregnancies...
  86. ncbi request reprint Use of novel immunohistochemical markers expressed in colonic adenocarcinoma to distinguish primary ovarian tumors from metastatic colorectal carcinoma
    Sanjay Logani
    Emory University School of Medicine, Atlanta, GA, USA
    Mod Pathol 18:19-25. 2005
    ..Diffuse expression of all three markers (CDX2, beta-catenin and P504S) in a tumor in the ovary was found to be virtually diagnostic of metastasis from a colorectal primary in this study...
  87. pmc Hepsin colocalizes with desmosomes and induces progression of ovarian cancer in a mouse model
    Jiangyong Miao
    Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA
    Int J Cancer 123:2041-7. 2008
    ..The ability of ectopic hepsin to induce tumor growth in mice is abrogated by the mutation of 3 critical residues in the catalytic domain, thus implicating the enzymatic activity of hepsin in promoting tumor progression...
  88. doi request reprint A practical approach to intraoperative consultation in gynecological pathology
    Patricia Baker
    Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    Int J Gynecol Pathol 27:353-65. 2008
    ..Lastly, intraoperative evaluation of lymph nodes including the role of sentinel lymph nodes is discussed...
  89. ncbi request reprint Administration of recombinant human erythropoietin alpha before autologous stem cell transplantation reduces transfusion requirement in multiple myeloma patients
    Massimo Martino
    Bone Marrow Transplantation Unit, Azienda Ospedaliera Bianchi Melacrino Morelli, 89100, Reggio, Calabria, Italy
    Support Care Cancer 13:182-7. 2005
    ..008). Independently of Hb levels at PBSCT, rHuEPO therapy was significantly associated with a lower risk of transfusion requirement. In conclusion, rHuEPO is shown to be effective when administered prior to high-dose therapy in MM...