Olivia I Okereke

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Ten-year change in plasma amyloid beta levels and late-life cognitive decline
    Olivia I Okereke
    Division of Aging and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Third Floor, Boston, MA 02115, USA
    Arch Neurol 66:1247-53. 2009
  2. pmc Phobic anxiety and cognitive performance over 4 years among community-dwelling older women in the nurses' health study
    Olivia I Okereke
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA Department of Epidemiology, Harvard School of Public Health, Boston, MA Electronic address
    Am J Geriatr Psychiatry 21:1125-34. 2013
  3. pmc The SIST-M: predictive validity of a brief structured clinical dementia rating interview
    Olivia I Okereke
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Alzheimer Dis Assoc Disord 26:225-31. 2012
  4. pmc Performance characteristics of plasma amyloid-beta 40 and 42 assays
    Olivia I Okereke
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    J Alzheimers Dis 16:277-85. 2009
  5. pmc A profile of impaired insulin degradation in relation to late-life cognitive decline: a preliminary investigation
    Olivia I Okereke
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Geriatr Psychiatry 24:177-82. 2009
  6. pmc Fasting plasma insulin, C-peptide and cognitive change in older men without diabetes: results from the Physicians' Health Study II
    Olivia I Okereke
    Divisions of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Neuroepidemiology 34:200-7. 2010
  7. ncbi request reprint Type 2 diabetes mellitus and cognitive decline in two large cohorts of community-dwelling older adults
    Olivia I Okereke
    Division of Aging and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Geriatr Soc 56:1028-36. 2008
  8. pmc Plasma C-peptide levels and rates of cognitive decline in older, community-dwelling women without diabetes
    Olivia I Okereke
    Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Psychoneuroendocrinology 33:455-61. 2008
  9. ncbi request reprint Plasma C-peptide and cognitive performance in older men without diabetes
    Olivia Okereke
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Am J Geriatr Psychiatry 14:1041-50. 2006
  10. ncbi request reprint Midlife plasma insulin-like growth factor I and cognitive function in older men
    Olivia I Okereke
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Clin Endocrinol Metab 91:4306-12. 2006

Detail Information

Publications38

  1. pmc Ten-year change in plasma amyloid beta levels and late-life cognitive decline
    Olivia I Okereke
    Division of Aging and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Third Floor, Boston, MA 02115, USA
    Arch Neurol 66:1247-53. 2009
    ..Plasma levels of amyloid beta peptide (Abeta) are potential biomarkers of early cognitive impairment and decline and of Alzheimer disease risk...
  2. pmc Phobic anxiety and cognitive performance over 4 years among community-dwelling older women in the nurses' health study
    Olivia I Okereke
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA Department of Epidemiology, Harvard School of Public Health, Boston, MA Electronic address
    Am J Geriatr Psychiatry 21:1125-34. 2013
    ..To examine the relation of phobic anxiety to late-life cognitive trajectory...
  3. pmc The SIST-M: predictive validity of a brief structured clinical dementia rating interview
    Olivia I Okereke
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Alzheimer Dis Assoc Disord 26:225-31. 2012
    ....
  4. pmc Performance characteristics of plasma amyloid-beta 40 and 42 assays
    Olivia I Okereke
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    J Alzheimers Dis 16:277-85. 2009
    ..While these preliminary findings suggest that measuring plasma Abeta(40) and Abeta(42) may be feasible in varied research settings, additional work in this area is necessary...
  5. pmc A profile of impaired insulin degradation in relation to late-life cognitive decline: a preliminary investigation
    Olivia I Okereke
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Int J Geriatr Psychiatry 24:177-82. 2009
    ..In preliminary analyses, we considered the relation of combined lower insulin secretion (c-peptide) and higher insulin--possibly a phenotype for impaired insulin degradation--to cognitive decline...
  6. pmc Fasting plasma insulin, C-peptide and cognitive change in older men without diabetes: results from the Physicians' Health Study II
    Olivia I Okereke
    Divisions of Aging, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Neuroepidemiology 34:200-7. 2010
    ..We examined prospectively relations of fasting insulin levels and insulin secretion to cognitive decline among healthy, community-dwelling older men without diabetes...
  7. ncbi request reprint Type 2 diabetes mellitus and cognitive decline in two large cohorts of community-dwelling older adults
    Olivia I Okereke
    Division of Aging and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Geriatr Soc 56:1028-36. 2008
    ..To relate diabetes mellitus (DM) status and duration to late-life cognitive impairment and decline in men and women...
  8. pmc Plasma C-peptide levels and rates of cognitive decline in older, community-dwelling women without diabetes
    Olivia I Okereke
    Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Psychoneuroendocrinology 33:455-61. 2008
    ....
  9. ncbi request reprint Plasma C-peptide and cognitive performance in older men without diabetes
    Olivia Okereke
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA, USA
    Am J Geriatr Psychiatry 14:1041-50. 2006
    ..Emerging evidence suggests that type 2 diabetes may be related to diminished cognition, but little data are available directly regarding the role of insulin levels...
  10. ncbi request reprint Midlife plasma insulin-like growth factor I and cognitive function in older men
    Olivia I Okereke
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Clin Endocrinol Metab 91:4306-12. 2006
    ..Emerging biological and epidemiological evidence suggests possible benefits of higher IGF-I levels in cognitive aging...
  11. ncbi request reprint Plasma IGF-I levels and cognitive performance in older women
    Olivia Okereke
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, 3rd Floor, 181 Longwood Avenue, Boston, MA 02115, USA
    Neurobiol Aging 28:135-42. 2007
    ..Emerging biologic and epidemiologic evidence suggests benefits of insulin-like growth factor-I (IGF-I) in cognitive aging...
  12. ncbi request reprint Plasma C peptide level and cognitive function among older women without diabetes mellitus
    Olivia Okereke
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
    Arch Intern Med 165:1651-6. 2005
    ..To help differentiate between the effects of diabetes and insulin, we examined the relation of insulin to cognitive function among nondiabetic participants of the Nurses' Health Study...
  13. pmc The Structured Interview & Scoring Tool-Massachusetts Alzheimer's Disease Research Center (SIST-M): development, reliability, and cross-sectional validation of a brief structured clinical dementia rating interview
    Olivia I Okereke
    Department of Psychiatry, Gerontology Research Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Arch Neurol 68:343-50. 2011
    ..The Clinical Dementia Rating (CDR) and CDR Sum-of-Boxes can be used to grade mild but clinically important cognitive symptoms of Alzheimer disease. However, sensitive clinical interview formats are lengthy...
  14. pmc Isotemporal substitution analysis for physical activity, television watching, and risk of depression
    Rania A Mekary
    Harvard School of Public Health, Building 2, 665 Huntington Avenue, Boston, MA 02115, USA
    Am J Epidemiol 178:474-83. 2013
    ..95) was found when 60 minutes/day of brisk walking replaced 60 minutes/day of television watching. Thus, the ISM could offer a more meaningful alternative to the standard nonsubstitution models to support public health recommendations. ..
  15. pmc Dietary fat types and 4-year cognitive change in community-dwelling older women
    Olivia I Okereke
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Ann Neurol 72:124-34. 2012
    ..A study was undertaken to relate dietary fat types to cognitive change in healthy community-based elders...
  16. pmc Seafood types and age-related cognitive decline in the Women's Health Study
    Dae Hyun Kim
    SM, Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Ave, Boston, MA 02115
    J Gerontol A Biol Sci Med Sci 68:1255-62. 2013
    ..However, benefits may vary by nutrient contents in different seafood types. We examined associations between total seafood consumption and cognitive decline and whether these associations differ by seafood types...
  17. pmc Relation between clinical depression risk and physical activity and time spent watching television in older women: a 10-year prospective follow-up study
    Michel Lucas
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    Am J Epidemiol 174:1017-27. 2011
    ..13 (95% confidence interval: 1.00, 1.27; P(trend) = 0.01). Analyses simultaneously considering PA and television watching suggested that both contributed independently to depression risk...
  18. pmc Depression and incident stroke in women
    An Pan
    Department of Nutrition and Epidemiology, Harvard School of Public Health, and Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
    Stroke 42:2770-5. 2011
    ..Depression has been associated with an increased risk of coronary heart disease, but prospective data for the association with stroke are limited...
  19. pmc Physical activity at midlife in relation to successful survival in women at age 70 years or older
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Ave, Boston, MA 02115, USA
    Arch Intern Med 170:194-201. 2010
    ..Physical activity is associated with reduced risks of chronic diseases and premature death. Whether physical activity is also associated with improved overall health among those who survive to older ages is unclear...
  20. pmc Mediterranean diet and cognitive function in older age
    Cecilia Samieri
    Department of Medicine, Channing Division of Network Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Epidemiology 24:490-9. 2013
    ..Adherence to a Mediterranean diet may help prevent cognitive decline in older age, but studies are limited. We examined the association of adherence to the Mediterranean diet with cognitive function and decline...
  21. pmc Alcohol consumption at midlife and successful ageing in women: a prospective cohort analysis in the nurses' health study
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Med 8:e1001090. 2011
    ..In this study, we prospectively examined alcohol use assessed at midlife in relation to successful ageing in a cohort of US women...
  22. pmc Plasma amyloid-β as a predictor of dementia and cognitive decline: a systematic review and meta-analysis
    Alain Koyama
    Department of Psychiatry, University of California at San Francisco, USA
    Arch Neurol 69:824-31. 2012
    ....
  23. pmc Relation between insulin, insulin-related factors, and plasma amyloid beta peptide levels at midlife in a population-based study
    Mary K Townsend
    Department of Epidemiology, Harvard School of Public Health, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Alzheimer Dis Assoc Disord 26:50-4. 2012
    ....
  24. pmc Cigarette smoking and completed suicide: results from 3 prospective cohorts of American adults
    Michel Lucas
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA Electronic address
    J Affect Disord 151:1053-8. 2013
    ..Prior reports have indicated a potential dose-response relationship between smoking and suicide. However, this relationship is controversial...
  25. ncbi request reprint C-reactive protein, interleukin-6, soluble tumor necrosis factor α receptor 2 and incident clinical depression
    Patricia O Chocano-Bedoya
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA Electronic address
    J Affect Disord 163:25-32. 2014
    ..Despite an extensive literature on the role of inflammation and depression, few studies have evaluated the association between inflammatory biomarkers and depression in a prospective manner, and results are inconclusive...
  26. doi request reprint Inflammatory dietary pattern and risk of depression among women
    Michel Lucas
    Department of Nutrition, Harvard School of Public Health, MA 02115, USA Department of Social and Preventive Medicine, Laval University, Québec G1V 2M2, Canada Electronic address
    Brain Behav Immun 36:46-53. 2014
    ..Inflammation is considered as a mechanism leading to depression, but the association between inflammatory dietary pattern and depression risk is unknown...
  27. pmc Prospective study on long-term dietary patterns and incident depression in middle-aged and older women
    Patricia O Chocano-Bedoya
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 98:813-20. 2013
    ..Although individual nutrients have been investigated in relation to depression risk, little is known about the overall role of diet in depression...
  28. pmc Long-term adherence to the Mediterranean diet is associated with overall cognitive status, but not cognitive decline, in women
    Cecilia Samieri
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    J Nutr 143:493-9. 2013
    ..These associations were similar to those observed in women 1-1.5 y apart in age. In summary, long-term MeDi adherence was related to moderately better cognition but not with cognitive change in this very large cohort of older women...
  29. pmc Bidirectional association between depression and metabolic syndrome: a systematic review and meta-analysis of epidemiological studies
    An Pan
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Diabetes Care 35:1171-80. 2012
    ..However, the results have been inconsistent. This meta-analysis aimed to summarize the current evidence from cross-sectional and prospective cohort studies that evaluated this association...
  30. pmc Depression and risk of stroke morbidity and mortality: a meta-analysis and systematic review
    An Pan
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Ave, Boston, MA 02115, USA
    JAMA 306:1241-9. 2011
    ..Several studies have suggested that depression is associated with an increased risk of stroke; however, the results are inconsistent...
  31. pmc Adiposity and weight change in mid-life in relation to healthy survival after age 70 in women: prospective cohort study
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, United States
    BMJ 339:b3796. 2009
    ..To examine the hypothesis that mid-life adiposity is associated with a reduced probability of maintaining an optimal health status among those who survive to older ages...
  32. ncbi request reprint Urinary incontinence and prevalence of high depressive symptoms in older black versus white women
    Mary K Townsend
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA
    Int Urogynecol J 25:823-9. 2014
    ..Thus, UI-related mental health issues could be a key consideration among black women. We hypothesized that the association between UI and depression might be stronger in black versus white women...
  33. doi request reprint Phobic anxiety symptom scores and incidence of type 2 diabetes in US men and women
    Maryam S Farvid
    Department of Nutrition, Harvard School of Public Health, Boston, MA, United States Electronic address
    Brain Behav Immun 36:176-82. 2014
    ..Emotional stress may be a risk factor for type 2 diabetes (T2D), but the relation between phobic anxiety symptoms and risk of T2D is uncertain...
  34. pmc High phobic anxiety is related to lower leukocyte telomere length in women
    Olivia I Okereke
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 7:e40516. 2012
    ..Yet, little is known about relations of anxiety to telomeres. We examined whether a typically chronic form of anxiety--phobic anxiety--is related to telomere length...
  35. pmc Coffee, caffeine, and risk of depression among women
    Michel Lucas
    Department of Nutrition, Harvard School of Public Health, and Department of Medicine, Brigham and Women s Hospital, 655 Huntington Ave, Boston, MA 02115, USA
    Arch Intern Med 171:1571-8. 2011
    ..However, studies that analyze prospectively the relationship between coffee or caffeine consumption and depression risk are scarce...
  36. pmc Physical activity levels and cognition in women with type 2 diabetes
    ELIZABETH E DEVORE
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Am J Epidemiol 170:1040-7. 2009
    ..Results were similar for cognitive decline. These findings indicate little overall association between physical activity and cognition after adjustment for disability factors in older women with type 2 diabetes...
  37. pmc Fasting insulin levels and cognitive decline in older women without diabetes
    Marieke van Oijen
    Department of Epidemiology Biostatistics and Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    Neuroepidemiology 30:174-9. 2008
    ..Type 2 diabetes has been associated with an increased risk of dementia. To assess possible independent effects of insulin, we investigated the relation of insulin levels to cognitive decline in nondiabetic women...
  38. ncbi request reprint Medical comorbidity in geriatric psychiatry
    Olivia I Okereke
    Am J Geriatr Psychiatry 13:177-9. 2005