Research Topics
Genomes and GenesSpecies | Marisa R NucciSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Detail Information
Publications
Distinctive cytogenetic profile in benign metastasizing leiomyoma: pathogenetic implicationsMarisa R Nucci
Department of Pathology, Divisions of Women s and Perinatal Pathology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Am J Surg Pathol 31:737-43. 2007....- Redefining early cervical neoplasia: recent progressMarisa R Nucci
Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital, Boston, MA 02445, USA
Adv Anat Pathol 14:1-10. 2007..In addition, practical issues in the diagnosis and management of squamous epithelial lesions, particularly the recognition of nonconventional variants and the application of biomarkers, are discussed... - Molecular analysis of the JAZF1-JJAZ1 gene fusion by RT-PCR and fluorescence in situ hybridization in endometrial stromal neoplasmsMarisa R Nucci
Division of Molecular Oncology, Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
Am J Surg Pathol 31:65-70. 2007..In addition, the detection of the fusion by reverse transcriptase-polymerase chain reaction or FISH for JJAZ1 at 7p15 may be diagnostically useful... - Arias-Stella reaction of the endocervix: a report of 18 cases with emphasis on its varied histology and differential diagnosisMarisa R Nucci
Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Am J Surg Pathol 28:608-12. 2004.... 
Serous tubal intraepithelial carcinoma: diagnostic reproducibility and its implicationsJoseph W Carlson
Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Int J Gynecol Pathol 29:310-4. 2010..In view of these findings, a diagnosis of STIC should be corroborated by a second pathologist, if feasible...- Coexisting intraepithelial serous carcinomas of the endometrium and fallopian tube: frequency and potential significanceElke A Jarboe
Department of Pathology, Division of Women s and Perinatal Pathology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
Int J Gynecol Pathol 28:308-15. 2009.... - Clinical outcome in diagnostically ambiguous foci of 'gland crowding' in the endometriumEric C Huang
Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Mod Pathol 23:1486-91. 2010..It underscores the importance of follow-up when some but not all of the criteria for EIN are encountered in the appropriate clinical setting... 
Intercepting early pelvic serous carcinoma by routine pathological examination of the fimbriaDana R Semmel
Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
Mod Pathol 22:985-8. 2009..The rationale for this strategy, and its potential effect on early detection and in uncovering persons or families potentially at risk for ovarian cancer, is discussed...- Histologic and immunohistochemical decision-making in endometrial adenocarcinomaLesley Lomo
Department of Pathology, Division of Women s and Perinatal Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
Mod Pathol 21:937-42. 2008..Because p53 is an important marker for endometrial adenocarcinoma outcome, and cannot be predicted in advance in indeterminate cases, p53 immunostaining should be employed in cases with observer disagreement in a binary system... - Biomarkers in diagnostic obstetric and gynecologic pathology: a reviewMarisa R Nucci
Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachussetts 02115, USA
Adv Anat Pathol 10:55-68. 2003.... - Embryonic stem cell transcription factors and D2-40 (podoplanin) as diagnostic immunohistochemical markers in ovarian germ cell tumorsMartin C Chang
Department of Pathology, Division of Women s and Perinatal Pathology, Brigham and Women s Hospital, Children s Hospital Boston, Massachusetts 02115, USA
Int J Gynecol Pathol 28:347-55. 2009..The inclusion of these markers should therefore be considered in cases of pure or mixed ovarian germ cell tumors that are difficult to classify, and to exclude nongerm cell tumor mimics... - High-grade fimbrial-ovarian carcinomas are unified by altered p53, PTEN and PAX2 expressionMichael H Roh
Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA
Mod Pathol 23:1316-24. 2010..PAX2 and PTEN, in addition to p53 and p16(ink4), comprise a potentially important gene combination in high-grade pelvic carcinogenesis... - Adenofibroma of the fimbria: a common entity that is indistinguishable from ovarian adenofibromaVeerle Bossuyt
Department of Pathology, Division of Women s and Perinatal Pathology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Int J Gynecol Pathol 27:390-7. 2008..Whether the shared tumor phenotype in these 2 organs is coincidental or interdependent bears further investigation... - The role of CD10 staining in distinguishing invasive endometrial adenocarcinoma from adenocarcinoma involving adenomyosisAlessandra F Nascimento
Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Mod Pathol 16:22-7. 2003..In contrast, absence of CD10 expression excludes involvement of adenomyosis by adenocarcinoma... - Fallopian tube correlates of ovarian serous borderline tumorsAnna R Laury
Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
Am J Surg Pathol 35:1759-65. 2011..Further study is warranted to clarify the relationship of the oviduct to serous neoplasia... - Meningothelial proliferations in mature cystic teratoma of the ovary: evidence for the common presence of cranially derived tissues paralleling anterior embryonic plate development. An analysis of 25 consecutive casesEleanor Chen
Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Am J Surg Pathol 34:1014-8. 2010.... - Stathmin-1 expression as a complement to p16 helps identify high-grade cervical intraepithelial neoplasia with increased specificityBrooke E Howitt
Department of Pathology, Division of Women s and Perinatal Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Am J Surg Pathol 37:89-97. 2013..Further studies correlating STMN staining with lesion persistence or morphologic progression, in the context of CIN grade, are warranted... - Peritoneal dissemination complicating morcellation of uterine mesenchymal neoplasmsMichael A Seidman
Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital Harvard Medical School, Boston, Massachussetts, United States of America
PLoS ONE 7:e50058. 2012..This study was undertaken to determine the frequency and clinical consequence of intraperitoneal dissemination of these neoplasms... - Low-grade, low-stage endometrioid endometrial adenocarcinoma: a clinicopathologic analysis of 324 cases focusing on frequency and pattern of myoinvasionCharles M Quick
Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
Int J Gynecol Pathol 31:337-43. 2012.... - A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancerMichael Herfs
Division of Women s and Perinatal Pathology, Department of Pathology, Brigham and Women s Hospital, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 109:10516-21. 2012.... - Atypical genital nevi. A clinicopathologic analysis of 56 casesBriana C Gleason
Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
Am J Surg Pathol 32:51-7. 2008..Awareness and recognition of this group of melanocytic lesions is important to avoid over diagnosis as melanoma with subsequent wide excision and possibly sentinel lymph node biopsy... - Serous carcinogenesis in the fallopian tube: a descriptive classificationElke Jarboe
Department of Pathology, Division of Women s and Perinatal Pathology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Int J Gynecol Pathol 27:1-9. 2008..Combined with recent reports associating STICs with pelvic serous cancer, this continuum of epithelial change validates the SCAT sequence and the fimbrial secretory cell as the site of origin for many serous carcinomas... - Hertig and beyond: a systematic and practical approach to the endometrial biopsyChristopher P Crum
Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Adv Anat Pathol 10:301-18. 2003..Algorithms for the laboratory management of cyclic changes, dysfunctional bleeding, and mixed-pattern endometria are provided, as are pitfalls in interpretation and exclusion of neoplasia... - The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumorCheng Han Lee
Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
Am J Surg Pathol 36:641-53. 2012..Thus, their distinction from typical JAZF1 ESS is important for prognostic and therapeutic purposes... - Fertility-sparing treatment in younger women with adenocarcinoma in situ of the cervixNehalennia VAN Hanegem
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
Gynecol Oncol 124:72-7. 2012..In women who desire future fertility, however, conservative therapy is an acceptable alternative. In this study we compare the outcomes for young women who underwent loop conization or were treated with cold knife conization... - Symposium part III: tumor-like glandular lesions of the uterine cervixMarisa R Nucci
Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Int J Gynecol Pathol 21:347-59. 2002..The entities that will be discussed include tunnel clusters, microglandular hyperplasia, mesonephric hyperplasia, endocervical glandular hyperplasia, and the Arias-Stella reaction... - Predictive value of FIGO and AJCC staging systems in patients with uterine leiomyosarcomaChandrajit P Raut
Department of Surgery, Brigham and Women s Hospital, Dana Farber Cancer Institute, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States
Eur J Cancer 45:2818-24. 2009..Neither has been validated in ULMS. We critically evaluated both systems to determine if either identified patient groups with distinct outcomes... - Distinction between endometrial and endocervical adenocarcinoma: an immunohistochemical studyDiego H Castrillon
Women's and Perinatal Pathology Division, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Int J Gynecol Pathol 21:4-10. 2002..EMA positivity was present in all 30 EMCAs and in 26 of 29 (90%) CCAs. We conclude that VIM and CEA are useful immunohistochemical markers in distinguishing EMCAs and CCAs, but CK7, CK20, and EMA are not useful in this distinction... - Ovarian mucinous and mixed epithelial carcinomas of mullerian (endocervical-like) type: a clinicopathologic analysis of four cases of an uncommon variant associated with endometriosisKenneth R Lee
Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Int J Gynecol Pathol 22:42-51. 2003..To better understand their clinicopathologic features and pathogenesis, this uncommon variant should be separated from the usual type in future studies of mucinous carcinomas of the ovary... - Fallopian tube prolapse mimicking aggressive angiomyxomaHeike Varnholt
Department of Pathology, Baystate Medical Center, Tufts University School of Medicine, Springfield, Massachusetts 01199, USA
Int J Gynecol Pathol 24:292-4. 2005..Condensation of eosinophilic fibrils around medium sized vessels was marked. This case of fallopian tube prolapse shows an unusual resemblance of aggressive angiomyxoma and thus poses a diagnostic pitfall... - Complete hydatidiform mole retaining a chromosome 11 of maternal origin: molecular genetic analysis of a caseRosemary A Fisher
Department of Cancer Medicine, Faculty of Medicine, Imperial College London, Charing Cross Hospital, London, UK
Mod Pathol 17:1155-60. 2004..Furthermore, these results provide an explanation for rare false negatives that can arise when p57(KIP2) is used as a diagnostic marker for complete moles... - Ewing family of tumours involving the vulva and vagina: report of a series of four casesW Glenn McCluggage
Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland
J Clin Pathol 60:674-80. 2007..In this study, four new cases of EFTs involving the vulva (three cases) or vagina (one case) are reported... - Risk of subsequent endometrial carcinoma associated with endometrial intraepithelial neoplasia classification of endometrial biopsiesJames V Lacey
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20852 7234, USA
Cancer 113:2073-81. 2008..The authors estimated progression risk associated with EIN among endometrial biopsies in a nested case-control study of EH progression...