G P Nielsen

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc CDKN2A gene deletions and loss of p16 expression occur in osteosarcomas that lack RB alterations
    G P Nielsen
    James Homer Wright Pathology Laboratories, Department of Pathology and Neurosurgical Service, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
    Am J Pathol 153:159-63. 1998
  2. doi request reprint Epithelioid hemangioma of bone revisited: a study of 50 cases
    G Petur Nielsen
    Department of Pathology and James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Surg Pathol 33:270-7. 2009
  3. ncbi request reprint Soft tissue aneurysmal bone cyst: a clinicopathologic study of five cases
    G Petur Nielsen
    James Homer Wright Pathology Laboratories, Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Am J Surg Pathol 26:64-9. 2002
  4. ncbi request reprint Tumors and diseases of the joint
    G Petur Nielsen
    Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Semin Diagn Pathol 28:37-52. 2011
  5. pmc Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation
    G P Nielsen
    Molecular Neuro Oncology Laboratory and the James Homer Wright Pathology Laboratories, Department of Pathology and Neurosurgical Service, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Pathol 155:1879-84. 1999
  6. ncbi request reprint Hyalinizing spindle cell tumor with giant rosettes: a report of three cases with ultrastructural analysis
    G P Nielsen
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    Am J Surg Pathol 23:1227-32. 1999
  7. ncbi request reprint Chordoma periphericum: a case report
    G P Nielsen
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    Am J Surg Pathol 25:263-7. 2001
  8. ncbi request reprint Primary pulmonary sarcoma: a clinicopathologic study of 26 cases
    S B Keel
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    Mod Pathol 12:1124-31. 1999
  9. ncbi request reprint Reticular perineurioma: a distinctive variant of soft tissue perineurioma
    J F Graadt van Roggen
    Departments of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Surg Pathol 25:485-93. 2001
  10. ncbi request reprint Chondroblastoma-like chondroma of soft tissue: an underrecognized variant and its differential diagnosis
    J M Cates
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School Boston, Massachusetts, USA
    Am J Surg Pathol 25:661-6. 2001

Collaborators

Detail Information

Publications15

  1. pmc CDKN2A gene deletions and loss of p16 expression occur in osteosarcomas that lack RB alterations
    G P Nielsen
    James Homer Wright Pathology Laboratories, Department of Pathology and Neurosurgical Service, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
    Am J Pathol 153:159-63. 1998
    ..This study suggests that CDKN2A is a tumor suppressor inactivated in osteosarcomas that lack RB mutations and that the p16-pRb cell-cycle control pathway is deregulated in a large number of high-grade osteosarcomas...
  2. doi request reprint Epithelioid hemangioma of bone revisited: a study of 50 cases
    G Petur Nielsen
    Department of Pathology and James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Surg Pathol 33:270-7. 2009
    ..Epithelioid hemangioma of bone is a benign lesion that may be multifocal and affect separate tissue and is successfully treated with curettage or marginal en bloc excision...
  3. ncbi request reprint Soft tissue aneurysmal bone cyst: a clinicopathologic study of five cases
    G Petur Nielsen
    James Homer Wright Pathology Laboratories, Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Am J Surg Pathol 26:64-9. 2002
    ..Soft tissue aneurysmal bone cyst is an uncommon benign tumor that can be treated by simple excision, and it should be distinguished from a variety of other reactive and neoplastic processes...
  4. ncbi request reprint Tumors and diseases of the joint
    G Petur Nielsen
    Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Semin Diagn Pathol 28:37-52. 2011
    ..These crystal deposits may be asymptomatic or cause severe pain or chronic joint destruction. Their accurate identification is important to guide appropriate therapy...
  5. pmc Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation
    G P Nielsen
    Molecular Neuro Oncology Laboratory and the James Homer Wright Pathology Laboratories, Department of Pathology and Neurosurgical Service, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Pathol 155:1879-84. 1999
    ....
  6. ncbi request reprint Hyalinizing spindle cell tumor with giant rosettes: a report of three cases with ultrastructural analysis
    G P Nielsen
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    Am J Surg Pathol 23:1227-32. 1999
    ..There was no ultrastructural evidence of neural differentiation to explain the focal S-100 protein and Leu-7 staining of the tumor cells...
  7. ncbi request reprint Chordoma periphericum: a case report
    G P Nielsen
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    Am J Surg Pathol 25:263-7. 2001
    ..Chordoma periphericum, a tumor that has the potential to metastasize, needs to be distinguished from parachordoma because no classic parachordoma has been reported to disseminate...
  8. ncbi request reprint Primary pulmonary sarcoma: a clinicopathologic study of 26 cases
    S B Keel
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA
    Mod Pathol 12:1124-31. 1999
    ..Immunohistochemistry and electron microscopy can be helpful in distinguishing primary pulmonary sarcoma from other tumors in the differential diagnosis...
  9. ncbi request reprint Reticular perineurioma: a distinctive variant of soft tissue perineurioma
    J F Graadt van Roggen
    Departments of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Surg Pathol 25:485-93. 2001
    ..Reticular perineurioma of soft tissue represents an unusual morphologic variant within the perineurioma group, which should be distinguished from myoepithelial tumors, extraskeletal myxoid chondrosarcoma, and myxoid synovial sarcoma...
  10. ncbi request reprint Chondroblastoma-like chondroma of soft tissue: an underrecognized variant and its differential diagnosis
    J M Cates
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Harvard Medical School Boston, Massachusetts, USA
    Am J Surg Pathol 25:661-6. 2001
    ..The clinicopathologic features of these chondroblastoma-like chondromas are discussed, emphasizing the characteristics that facilitate their accurate identification...
  11. pmc NHE-RF, a merlin-interacting protein, is primarily expressed in luminal epithelia, proliferative endometrium, and estrogen receptor-positive breast carcinomas
    A O Stemmer-Rachamimov
    Molecular Neuro-Oncology Laboratory, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Am J Pathol 158:57-62. 2001
    ..Furthermore, estrogen receptor status and NHE-RF expression correlate closely in breast carcinoma specimens. These findings support a role for NHE-RF in estrogen signaling...
  12. doi request reprint Use of electron microscopy in core biopsy diagnosis of oncocytic renal tumors
    N B Johnson
    Beth Israel Deaconess Medical Center, Department of Pathology, Boston, MA 02114, USA
    Ultrastruct Pathol 34:189-94. 2010
    ..Twenty renal needle core biopsies were evaluated. Despite formalin fixation and paraffin embedding, the classic ultrastructural features of these neoplasms were retained, revealing 80% sensitivity and 100% specificity by initial work-up...
  13. ncbi request reprint Long-term results of combined modality therapy in primary bone lymphomas
    P Fidias
    Department of Medical Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    Int J Radiat Oncol Biol Phys 45:1213-8. 1999
    ..To report the Massachusetts General Hospital experience in the management of patients with primary bone lymphoma (PBL) treated with combined modality therapy (CMT)...
  14. ncbi request reprint Radiation therapy for control of soft-tissue sarcomas resected with positive margins
    Thomas F DeLaney
    Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Int J Radiat Oncol Biol Phys 67:1460-9. 2007
    ..Positive margins (PM) remain after surgery in some soft-tissue sarcoma (STS) patients. We investigated the efficacy of radiation therapy (RT) in STS patients with PM...
  15. ncbi request reprint A spatially and temporally restricted mouse model of soft tissue sarcoma
    David G Kirsch
    Center for Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA
    Nat Med 13:992-7. 2007
    ..Therefore, the intrinsic pathway of apoptosis seems sufficient to mediate p53 tumor suppression in an epithelial cancer, but not in this model of soft tissue sarcoma...