Yasuko Nagasaka

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. pmc Brief periods of nitric oxide inhalation protect against myocardial ischemia-reperfusion injury
    Yasuko Nagasaka
    Anesthesia Center for Critical Care Research, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Anesthesiology 109:675-82. 2008
  2. pmc Soluble guanylate cyclase-α1 is required for the cardioprotective effects of inhaled nitric oxide
    Yasuko Nagasaka
    Department of Anesthesia, Critical Care, and Pain Medicine, Anesthesia Center for Critical Care Research, Massachusetts General Hospital, Harvard Medical School, Boston, 02114, USA
    Am J Physiol Heart Circ Physiol 300:H1477-83. 2011
  3. pmc Nitric oxide regulates pulmonary vascular smooth muscle cell expression of the inducible cAMP early repressor gene
    Andrea U Steinbicker
    Anesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, 55 Fruit Street, Boston, MA 02114, USA
    Nitric Oxide 25:294-302. 2011
  4. pmc Bone marrow MyD88 signaling modulates neutrophil function and ischemic myocardial injury
    Yan Feng
    Department of Anesthesia and Critical Care, Massachusetts General Hospital, GRJ 4 444, 55 Fruit St, Boston, MA 02114, USA
    Am J Physiol Cell Physiol 299:C760-9. 2010

Detail Information

Publications4

  1. pmc Brief periods of nitric oxide inhalation protect against myocardial ischemia-reperfusion injury
    Yasuko Nagasaka
    Anesthesia Center for Critical Care Research, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Anesthesiology 109:675-82. 2008
    ..Prolonged breathing of nitric oxide reduces myocardial ischemia-reperfusion injury, but the precise mechanisms responsible for the cardioprotective effects of inhaled nitric oxide are incompletely understood...
  2. pmc Soluble guanylate cyclase-α1 is required for the cardioprotective effects of inhaled nitric oxide
    Yasuko Nagasaka
    Department of Anesthesia, Critical Care, and Pain Medicine, Anesthesia Center for Critical Care Research, Massachusetts General Hospital, Harvard Medical School, Boston, 02114, USA
    Am J Physiol Heart Circ Physiol 300:H1477-83. 2011
    ..The cardioprotective effects of inhaled NO require the presence of sGCα(1). Moreover, our studies suggest that BM-derived cells are key mediators of the ability of NO to reduce cardiac ischemia-reperfusion injury...
  3. pmc Nitric oxide regulates pulmonary vascular smooth muscle cell expression of the inducible cAMP early repressor gene
    Andrea U Steinbicker
    Anesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, 55 Fruit Street, Boston, MA 02114, USA
    Nitric Oxide 25:294-302. 2011
    ..The induction of ICER in GSNO-treated RPaSMC highlights a novel cross-talk mechanism between cGMP and cAMP signaling pathways...
  4. pmc Bone marrow MyD88 signaling modulates neutrophil function and ischemic myocardial injury
    Yan Feng
    Department of Anesthesia and Critical Care, Massachusetts General Hospital, GRJ 4 444, 55 Fruit St, Boston, MA 02114, USA
    Am J Physiol Cell Physiol 299:C760-9. 2010
    ..MyD88 signaling in bone marrow-derived circulating cells may play a specific and critical role in the development of myocardial I/R-induced injury...