Kiran Musunuru

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi request reprint Current role of pharmacogenomics in cardiovascular medicine
    Kiran Musunuru
    Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, 185 Cambridge St CPZN 5th floor, Boston, MA, USA
    Curr Treat Options Cardiovasc Med 13:302-12. 2011
  2. pmc Atherogenic dyslipidemia: cardiovascular risk and dietary intervention
    Kiran Musunuru
    Cardiology Division, Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, CPZN 5th floor, Boston, MA 02114, USA
    Lipids 45:907-14. 2010
  3. pmc From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
    Kiran Musunuru
    Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Nature 466:714-9. 2010
  4. doi request reprint Defining the spectrum of alleles that contribute to blood lipid concentrations in humans
    Sekar Kathiresan
    Cardiovascular Disease Prevention Center, Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Curr Opin Lipidol 19:122-7. 2008
  5. pmc Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
    Sekar Kathiresan
    Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Nat Genet 41:334-41. 2009
  6. doi request reprint The clinical utility of high-sensitivity C-reactive protein in cardiovascular disease and the potential implication of JUPITER on current practice guidelines
    Samia Mora
    Divisions of Preventive and Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Clin Chem 55:219-28. 2009
  7. doi request reprint Genetics of coronary artery disease
    Kiran Musunuru
    Center for Human Genetic Research and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02108, USA
    Annu Rev Genomics Hum Genet 11:91-108. 2010
  8. pmc Common variants at 30 loci contribute to polygenic dyslipidemia
    Sekar Kathiresan
    Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Nat Genet 41:56-65. 2009
  9. pmc Clinical efficacy and safety of statins in managing cardiovascular risk
    Navin K Kapur
    Division of Cardiology, Tufts University, New England Medical Center, Boston, MA 02111, USA
    Vasc Health Risk Manag 4:341-53. 2008
  10. pmc Ion mobility analysis of lipoprotein subfractions identifies three independent axes of cardiovascular risk
    Kiran Musunuru
    Center for Human Genetic Research, Cardiology Division, Massachusetts General Hospital, Boston, MA, USA
    Arterioscler Thromb Vasc Biol 29:1975-80. 2009

Detail Information

Publications10

  1. ncbi request reprint Current role of pharmacogenomics in cardiovascular medicine
    Kiran Musunuru
    Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, 185 Cambridge St CPZN 5th floor, Boston, MA, USA
    Curr Treat Options Cardiovasc Med 13:302-12. 2011
    ....
  2. pmc Atherogenic dyslipidemia: cardiovascular risk and dietary intervention
    Kiran Musunuru
    Cardiology Division, Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, CPZN 5th floor, Boston, MA 02114, USA
    Lipids 45:907-14. 2010
    ..Achieving a better understanding of the genetic and dietary influences underlying atherogenic dyslipidemia may provide clues to improved interventions to reduce the risk of cardiovascular disease in high-risk individuals...
  3. pmc From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
    Kiran Musunuru
    Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Nature 466:714-9. 2010
    ..We also demonstrate that common noncoding DNA variants identified by GWASs can directly contribute to clinical phenotypes...
  4. doi request reprint Defining the spectrum of alleles that contribute to blood lipid concentrations in humans
    Sekar Kathiresan
    Cardiovascular Disease Prevention Center, Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Curr Opin Lipidol 19:122-7. 2008
    ..This review summarizes recent genome-wide association studies for lipid phenotypes, and evaluates the next steps needed to obtain a full picture of genotype-phenotype correlation and apply these findings to inform clinical practice...
  5. pmc Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
    Sekar Kathiresan
    Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Nat Genet 41:334-41. 2009
    ..SNPs at nine loci were reproducibly associated with myocardial infarction, but tests of common and rare CNVs failed to identify additional associations with myocardial infarction risk...
  6. doi request reprint The clinical utility of high-sensitivity C-reactive protein in cardiovascular disease and the potential implication of JUPITER on current practice guidelines
    Samia Mora
    Divisions of Preventive and Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Clin Chem 55:219-28. 2009
    ....
  7. doi request reprint Genetics of coronary artery disease
    Kiran Musunuru
    Center for Human Genetic Research and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02108, USA
    Annu Rev Genomics Hum Genet 11:91-108. 2010
    ..A key challenge now is to move from mapping loci to pinpointing causal genes and variants, and to develop a molecular understanding of how these genes lead to coronary disease...
  8. pmc Common variants at 30 loci contribute to polygenic dyslipidemia
    Sekar Kathiresan
    Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Nat Genet 41:56-65. 2009
    ..These results suggest that the cumulative effect of multiple common variants contributes to polygenic dyslipidemia...
  9. pmc Clinical efficacy and safety of statins in managing cardiovascular risk
    Navin K Kapur
    Division of Cardiology, Tufts University, New England Medical Center, Boston, MA 02111, USA
    Vasc Health Risk Manag 4:341-53. 2008
    ..This review provides a detailed understanding of the clinical efficacy and safety of statins with a particular emphasis on the third generation drug, rosuvastatin...
  10. pmc Ion mobility analysis of lipoprotein subfractions identifies three independent axes of cardiovascular risk
    Kiran Musunuru
    Center for Human Genetic Research, Cardiology Division, Massachusetts General Hospital, Boston, MA, USA
    Arterioscler Thromb Vasc Biol 29:1975-80. 2009
    ....