Michael F Murray

Summary

Affiliation: Massachusetts General Hospital
Country: USA

Publications

  1. ncbi Nicotinamide: an oral antimicrobial agent with activity against both Mycobacterium tuberculosis and human immunodeficiency virus
    Michael F Murray
    Department of Medicine, Brigham and Women s Hospital, Harvard University, Boston, MA 02115, USA
    Clin Infect Dis 36:453-60. 2003
  2. ncbi Tryptophan depletion and HIV infection: a metabolic link to pathogenesis
    Michael F Murray
    Department of Medicine, Brigham and Women s Hospital, Harvard University, Boston, MA 02115 6110, USA
    Lancet Infect Dis 3:644-52. 2003
  3. ncbi The human indoleamine 2,3-dioxygenase gene and related human genes
    Michael F Murray
    Clinical Chief, Genetics Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Curr Drug Metab 8:197-200. 2007
  4. doi Insights into therapy: tryptophan oxidation and HIV infection
    Michael F Murray
    Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Sci Transl Med 2:32ps23. 2010
  5. ncbi siRNA-directed inhibition of HIV-1 infection
    Carl D Novina
    Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Nat Med 8:681-6. 2002

Research Grants

  1. RNA directed silencing of HIV and SIV receptors
    Michael Murray; Fiscal Year: 2004

Collaborators

  • J Lieberman
  • Carl D Novina
  • Derek M Dykxhoorn
  • Paul J Beresford
  • Phillip A Sharp
  • Jonathan Riess
  • Ronald G Collman
  • Sang Kyung Lee
  • Premlata Shankar

Detail Information

Publications5

  1. ncbi Nicotinamide: an oral antimicrobial agent with activity against both Mycobacterium tuberculosis and human immunodeficiency virus
    Michael F Murray
    Department of Medicine, Brigham and Women s Hospital, Harvard University, Boston, MA 02115, USA
    Clin Infect Dis 36:453-60. 2003
    ..tuberculosis and HIV...
  2. ncbi Tryptophan depletion and HIV infection: a metabolic link to pathogenesis
    Michael F Murray
    Department of Medicine, Brigham and Women s Hospital, Harvard University, Boston, MA 02115 6110, USA
    Lancet Infect Dis 3:644-52. 2003
    ..Additional study of this metabolism could lead to improved treatment strategies for patients with HIV infection. In this review I focus on the potential links between disturbed tryptophan metabolism and pathogenesis...
  3. ncbi The human indoleamine 2,3-dioxygenase gene and related human genes
    Michael F Murray
    Clinical Chief, Genetics Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Curr Drug Metab 8:197-200. 2007
    ..In addition to INDO and TDO2 a third related gene, the Indoleamine-Pyrrole 2,3 Dioxygenase-like 1 (INDOL1) gene will be discussed. INDOL1 is a gene of unknown function that lies adjacent to INDO on chromosome 8...
  4. doi Insights into therapy: tryptophan oxidation and HIV infection
    Michael F Murray
    Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Sci Transl Med 2:32ps23. 2010
    ..TOx regulation is a therapeutic target for other diseases, such as cancer and autoimmune disorders. Here TOx control is examined with an eye to eventual therapeutic intervention in HIV disease...
  5. ncbi siRNA-directed inhibition of HIV-1 infection
    Carl D Novina
    Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Nat Med 8:681-6. 2002
    ..siRNAs effectively inhibit pre- and/or post-integration infection events in the HIV-1 life cycle. Thus, siRNAs may have potential for therapeutic intervention in HIV-1 and other viral infections...

Research Grants1

  1. RNA directed silencing of HIV and SIV receptors
    Michael Murray; Fiscal Year: 2004
    ..abstract_text> ..